Cardiac expression of Tnnt1 requires the GATA4-FOG2 transcription complex

TheScientificWorldJournal

Volumn 9, Issue , 2009, Pages 575-587

  Manuylov, Nikolay L ^a   Tevosian, Sergei G ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

FOG2; GATA4; Heart; Tnnt1; Zfpm2

Indexed keywords

RNA; TRANSCRIPTION FACTOR GATA 4; TROPONIN T; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 2; DNA BINDING PROTEIN; GATA4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; ZFPM2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE CONTROL; GENE EXPRESSION; GENOMIC FRAGMENT; HEART ATRIUM; HEART DEVELOPMENT; HEART MUSCLE; HEART VENTRICLE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN INTERACTION; SKELETAL MUSCLE; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEART; IN SITU HYBRIDIZATION; MALE; METABOLISM; MOUSE MUTANT; PRENATAL DEVELOPMENT; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ANIMALS; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TROPONIN T;

EID: 70349336700     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2009.75     Document Type: Article

References (41)

1. Cantor, A.B. and Orkin, S.H. (2005) Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins. Semin. Cell Dev. Biol. 16, 117-128.
2. Sorrentino, R.P., Gajewski, K.M., and Schulz, R.A. (2005) GATA factors in Drosophila heart and blood cell development. Semin. Cell Dev. Biol. 16, 107-116. (Pubitemid 40126881)
3. Lu, J.R., McKinsey, T.A., Xu, H., Wang, D.Z., Richardson, J.A., and Olson, E.N. (1999) FOG-2, a heart- and brainenriched cofactor for GATA transcription factors. Mol. Cell Biol. 19, 4495-4502. (Pubitemid 29242022)
4. Svensson, E.C., Tufts, R.L., Polk, C.E., and Leiden, J.M. (1999) Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc. Natl. Acad. Sci. U. S. A. 96, 956-961. (Pubitemid 29072165)
5. Tevosian, S.G., Deconinck, A.E., Cantor, A.B., Rieff, H.I., Fujiwara, Y., Corfas, G., and Orkin, S.H. (1999) FOG-2: a novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped. Proc. Natl. Acad. Sci. U. S. A. 96, 950-955. (Pubitemid 29072164)
6. Svensson, E.C., Huggins, G.S., Lin, H., Clendenin, C., Jiang, F., Tufts, R., Dardik, F.B., and Leiden, J.M. (2000) A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nat. Genet. 25, 353-356. (Pubitemid 30437328)
7. Tevosian, S.G., Deconinck, A.E., Tanaka, M., Schinke, M., Litovsky, S.H., Izumo, S., Fujiwara, Y., and Orkin, S.H. (2000) FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell 101, 729-739.
8. Novak, K. (2000) Lost in the FOG. Nat. Med. 6, 864.
9. Shalaby, F., Rossant, J., Yamaguchi, T.P., Breitman, M.L., and Schuh, A.C. (1995) Failure of blood island formation and vasculogenesis in flk-1 deficient mice. Nature 376, 62-66.
10. Bautch, V.L. and Ambler, C.A. (2004) Assembly and patterning of vertebrate blood vessels. Trends Cardiovasc. Med. 14, 138-143.
11. Kuo, C.T., Morrisey, E.E., Anandappa, R., Sigrist, K., Lu, M.M., Parmacek, M.S., Soudais, C., and Leiden, J.M. (1997) GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11, 1048-1060. (Pubitemid 27199883)
12. Molkentin, J.D., Lin, Q., Duncan, S.A., and Olson, E.N. (1997) Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11, 1061-1072. (Pubitemid 27199884)
13. Narita, N., Bielinska, M., and Wilson, D.B. (1997) Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cells. Development 124, 3755-3764. (Pubitemid 27482972)
14. Crispino, J.D., Lodish, M.B., Thurberg, B.L., Litovsky, S.H., Collins, T., Molkentin, J.D., and Orkin, S.H. (2001) Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 15, 839-844. (Pubitemid 32295065)
15. Watt, A.J., Battle, M.A., Li, J., and Duncan, S.A. (2004) GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc. Natl. Acad. Sci. U. S. A. 101, 12573-12578. (Pubitemid 39122065)
16. Oka, T., Maillet, M., Watt, A.J., Schwartz, R.J., Aronow, B.J., Duncan, S.A., and Molkentin, J.D. (2006) Cardiacspecific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ. Res. 98, 837-845. (Pubitemid 43755268)
17. Zeisberg, E.M., Ma, Q., Juraszek, A.L., Moses, K., Schwartz, R.J., Izumo, S., and Pu, W.T. (2005) Morphogenesis of the right ventricle requires myocardial expression of Gata4. J. Clin. Invest. 115, 1522-1531. (Pubitemid 40814660)
18. Garg, V., Kathiriya, I.S., Barnes, R., Schluterman, M.K., King, I.N., Butler, C.A., Rothrock, C.R., Eapen, R.S., Hirayama-Yamada, K., Joo, K., Matsuoka, R., Cohen, J.C., and Srivastava, D. (2003) GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 6, 6.
19. Tevosian, S.G., Albrecht, K.H., Crispino, J.D., Fujiwara, Y., Eicher, E.M., and Orkin, S.H. (2002) Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development 129, 4627-4634. (Pubitemid 35203743)
20. Chee, M., Yang, R., Hubbell, E., Berno, A., Huang, X.C., Stern, D., Winkler, J., Lockhart, D.J., Morris, M.S., and Fodor, S.P. (1996) Accessing genetic information with high-density DNA arrays. Science 274, 610-614. (Pubitemid 26360440)
21. Lipshutz, R.J., Fodor, S.P., Gingeras, T.R., and Lockhart, D.J. (1999) High density synthetic oligonucleotide arrays. Nat. Genet. 21, 20-24.
22. Adameyko, I.I., Mudry, R.E., Houston-Cummings, N.R., Veselov, A.P., Gregorio, C.C., and Tevosian, S.G. (2005) Expression and regulation of mouse SERDIN1, a highly conserved cardiac-specific leucine-rich repeat protein. Dev. Dyn. 233, 540-552.
23. Wilkinson, D.G. (1992) In Situ Hybridization. IRL Press, Oxford.
24. Manuylov, N.L., Manuylova, E., Avdoshina, V., and Tevosian, S. (2008) Serdin1/Lrrc10 is dispensable for mouse development. Genesis 46, 441-446.
25. Smagulova, F.O., Manuylov, N.L., Leach, L.L., and Tevosian, S.G. (2008) GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development. BMC Dev. Biol. 8, 67.
26. Krishan, K., Morgan, M.J., Zhao, W., and Dhoot, G.K. (2000) Slow troponin T mRNA in striated muscles is expressed in both cell type and developmental stage specific manner. J. Muscle Res. Cell Motil. 21, 527-536. (Pubitemid 32064043)
27. Wang, Q., Reiter, R.S., Huang, Q.Q., Jin, J.P., and Lin, J.J. (2001) Comparative studies on the expression patterns of three troponin T genes during mouse development. Anat. Rec. 263, 72-84.
28. Subbarayan, V., Mark, M., Messadeq, N., Rustin, P., Chambon, P., and Kastner, P. (2000) RXRalpha overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRalpha-null fetuses. J. Clin. Invest. 105, 387-394. (Pubitemid 30094459)
29. Palermo, J., Gulick, J., Colbert, M., Fewell, J., and Robbins, J. (1996) Transgenic remodeling of the contractile apparatus in the mammalian heart. Circ. Res. 78, 504-509. (Pubitemid 26068965)
30. Cullen, M.E., Dellow, K.A., and Barton, P.J. (2004) Structure and regulation of human troponin genes. Mol. Cell. Biochem. 263, 81-90. (Pubitemid 39256147)
31. Dutheil, N., Yoon-Robarts, M., Ward, P., Henckaerts, E., Skrabanek, L., Berns, K.I., Campagne, F., and Linden, R.M. (2004) Characterization of the mouse adeno-associated virus AAVS1 ortholog. J. Virol. 78, 8917-8921. (Pubitemid 39025157)
32. Tan, I., Ng, C.H., Lim, L., and Leung, T. (2001) Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton. J. Biol. Chem. 276, 21209-21216. (Pubitemid 37413109)
33. Ovcharenko, I., Nobrega, M.A., Loots, G.G., and Stubbs, L. (2004) ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res. 32, W280-286. (Pubitemid 38997344)
34. Barton, P.J., Felkin, L.E., Koban, M.U., Cullen, M.E., Brand, N.J., and Dhoot, G.K. (2004) The slow skeletal muscle troponin T gene is expressed in developing and diseased human heart. Mol. Cell. Biochem. 263, 91-97.
35. Bhattacharya, B., Miura, T., Brandenberger, R., Mejido, J., Luo, Y., Yang, A.X., Joshi, B.H., Ginis, I., Thies, R.S., Amit, M., Lyons, I., Condie, B.G., Itskovitz-Eldor, J., Rao, M.S., and Puri, R.K. (2004) Gene expression in human embryonic stem cell lines: unique molecular signature. Blood 103, 2956-2964. (Pubitemid 38451667)
36. Butte, A.J. and Kohane, I.S. (2006) Creation and implications of a phenome-genome network. Nat. Biotechnol. 24, 55-62.
37. Lee, C.K., Allison, D.B., Brand, J., Weindruch, R., and Prolla, T.A. (2002) Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc. Natl. Acad. Sci. U. S. A. 99, 14988-14993. (Pubitemid 35334597)
38. Lowe, X.R., Lu, X., Marchetti, F., and Wyrobek, A.J. (2007) The expression of Troponin T1 gene is induced by ketamine in adult mouse brain. Brain Res. 1174, 7-17. (Pubitemid 47451356)
39. Johnston, J.J., Kelley, R.I., Crawford, T.O., Morton, D.H., Agarwala, R., Koch, T., Schaffer, A.A., Francomano, C.A., and Biesecker, L.G. (2000) A novel nemaline myopathy in the Amish caused by a mutation in troponin T1. Am. J. Hum. Genet. 67, 814-821. (Pubitemid 30740134)
40. Ahmad, F., Banerjee, S.K., Lage, M.L., Huang, X.N., Smith, S.H., Saba, S., Rager, J., Conner, D.A., Janczewski, A.M., Tobita, K., Tinney, J.P., Moskowitz, I.P., Perez-Atayde, A.R., Keller, B.B., Mathier, M.A., Shroff, S.G., Seidman, C.E., and Seidman, J.G. (2008) The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. PLoS ONE 3, e2642.
41. Nishii, K., Morimoto, S., Minakami, R., Miyano, Y., Hashizume, K., Ohta, M., Zhan, D.Y., Lu, Q.W., and Shibata, Y. (2008) Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo. Dev. Biol. 322, 65-73.