Origins of retinal intrinsic signals: A series of experiments on retinas of macaque monkeys

Japanese Journal of Ophthalmology

Volumn 53, Issue 4, 2009, Pages 297-314

  Tsunoda, Kazushige ^a,b   Hanazono, Gen ^a,b   Inomata, Koichi ^a,b   Kazato, Yoko ^a,b   Suzuki, Wataru ^b   Tanifuji, Manabu ^b  

^a National Hospital Organization   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Functional imaging; Intrinsic signals; Monkey; Optical imaging; Retina

Indexed keywords

DIAGNOSTIC IMAGING; ELECTRORETINOGRAM; EXPERIMENTAL MONKEY; INTRINSIC SIGNAL IMAGING; NONHUMAN; OPTIC DISK; PRIORITY JOURNAL; RETINA; RETINA MACULA LUTEA; REVIEW; VISUAL CORTEX;

ANIMALS; DARK ADAPTATION; ELECTRORETINOGRAPHY; EVOKED POTENTIALS, VISUAL; LASER-DOPPLER FLOWMETRY; MACACA; MACACA MULATTA; PHOTIC STIMULATION; REGIONAL BLOOD FLOW; RETINA; RETINAL VESSELS;

EID: 70349312284     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-009-0686-3     Document Type: Review

References (100)

1. R.H. Webb G.W. Hughes 1981 Scanning laser ophthalmoscope IEEE Trans Biomed Eng 28 488 492
2. M.A. Mainster G.T. Timberlake R.H. Webb G.W. Hughes 1982 Scanning laser ophthalmoscopy. Clinical applications Ophthalmology 89 852 857
3. D. Huang E.A. Swanson C.P. Lin 1991 Optical coherence tomography Science 254 1178 1181
4. M.R. Hee J.A. Izatt E.A. Swanson 1995 Optical coherence tomography of the human retina Arch Ophthalmol 113 325 332
5. W.A. Rushton 1956 The difference spectrum and the photosensitivity of rhodopsin in the living human eye J Physiol 134 11 29
6. C. Hood W.A. Rushton 1971 The Florida retinal densitometer J Physiol 217 213 229
7. W.A. Rushton 1963 Cone pigment kinetics in the protanope J Physiol 168 374 388
8. M. Alpern F. Maaseidvaag N. Oba 1971 The kinetics of cone visual pigments in man Vision Res 11 539 549
9. M. Alpern 1971 Rhodopsin kinetics in the human eye J Physiol 217 447 471
10. D. van Norren J. van de Kraats 1989 Retinal densitometer with the size of a fundus camera Vision Res 29 369 374
11. P.E. Kilbride J.S. Read G.A. Fishman M. Fishman 1983 Determination of human cone pigment density difference spectra in spatially resolved regions of the fovea Vision Res 23 1341 1350
12. P.E. Kilbride K.M. Keehan 1990 Visual pigments in the human macula assessed by imaging fundus reflectometry Appl Opt 29 1427 1435
13. D.J. Faulkner C.M. Kemp 1984 Human rhodopsin measurement using a T.V.-based imaging fundus reflectometer Vision Res 24 221 231
14. C.M. Kemp D.J. Faulkner S.G. Jacobson 1988 The distribution and kinetics of visual pigments in the cat retina Invest Ophthalmol Vis Sci 29 1056 1065
15. C.M. Kemp S.G. Jacobson D.J. Faulkner 1988 Two types of visual dysfunction in autosomal dominant retinitis pigmentosa Invest Ophthalmol Vis Sci 29 1235 1241
16. D. van Norren J. van de Kraats 1989 Imaging retinal densitometry with a confocal scanning laser ophthalmoscope Vis Res 29 1825 1830
17. A.E. Elsner S.A. Burns G.W. Hughes R.H. Webb 1992 Reflectometry with a scanning laser ophthalmoscope Appl Opt 31 3697 3710
18. A.E. Elsner S.A. Burns E. Beausencourt J.J. Weiter 1998 Foveal cone photopigment distribution: small alterations associated with macular pigment distribution Invest Ophthalmol Vis Sci 39 2394 2404
19. A. Zepeda C. Arias F. Sengpiel 2004 Optical imaging of intrinsic signals: recent developments in the methodology and its applications J Neurosci Methods 136 1 21
20. D.Y. Ts'o R.D. Frostig E.E. Lieke A. Grinvald 1990 Functional organization of primate visual cortex revealed by high resolution optical imaging Science 249 417 420
21. R.D. Frostig E.E. Lieke D.Y. Ts'o A. Grinvald 1990 Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals Proc Natl Acad Sci U S A 87 6082 6086
22. A.W. Roe D.Y. Ts'o 1995 Visual topography in primate V2: multiple representation across functional stripes J Neurosci 15 3689 3715
23. G.M. Ghose D.Y. Ts'o 1997 Form processing modules in primate area V4 J Neurophysiol 77 2191 2196
24. D. Malonek R.B. Tootell A. Grinvald 1994 Optical imaging reveals the functional architecture of neurons processing shape and motion in owl monkey area MT Proc R Soc Lond B Biol Sci 258 109 119
25. K. Tsunoda Y. Yamane M. Nishizaki M. Tanifuji 2001 Complex objects are represented in macaque inferotemporal cortex by the combination of feature columns Nat Neurosci 4 832 838
26. B.A. MacVicar D. Hochman 1991 Imaging of synaptically evoked intrinsic optical signals in hippocampal slices J Neurosci 11 1458 1469
27. T. Bonhoeffer A. Grinvald 1996
28. M. Weliky K. Kandler D. Fitzpatrick L.C. Katz 1995 Patterns of excitation and inhibition evoked by horizontal connections in visual cortex share a common relationship to orientation columns Neuron 15 541 552
29. A. Das C.D. Gilbert 1995 Long-range horizontal connections and their role in cortical reorganization revealed by optical recording of cat primary visual cortex Nature 375 780 784
30. K. Tsunoda Y. Oguchi G. Hanazono M. Tanifuji 2004 Mapping cone- and rod-induced retinal responsiveness in macaque retina by optical imaging Invest Ophthalmol Vis Sci 45 3820 3826
31. M. Crittin C.E. Riva 2004 Functional imaging of the human papilla and peripapillary region based on flicker-induced reflectance changes Neurosci Lett 360 141 144
32. M.D. Abramoff Y.H. Kwon D. Ts'o 2006 Visual stimulus-induced changes in human near-infrared fundus reflectance Invest Ophthalmol Vis Sci 47 715 721
33. K. Grieve A. Roorda 2008 Intrinsic signals from human cone photoreceptors Invest Ophthalmol Vis Sci 49 713 719
34. D.A. Nelson S. Krupsky A. Pollack 2005 Special report: noninvasive multi-parameter functional optical imaging of the eye Ophthalmic Surg Lasers Imaging 36 57 66
35. H.H. Harary J.E. Brown L.H. Pinto 1978 Rapid light-induced changes in near infrared transmission of rods in Bufo marinus Science 202 1083 1085
36. X.C. Yao A. Yamauchi B. Perry J.S. George 2005 Rapid optical coherence tomography and recording functional scattering changes from activated frog retina Appl Opt 44 2019 2023
37. G. Hanazono K. Tsunoda K. Shinoda K. Tsubota Y. Miyake M. Tanifuji 2007 Intrinsic signal imaging in macaque retina reveals different types of flash-induced light reflectance changes of different origins Invest Ophthalmol Vis Sci 48 2903 2912
38. K. Inomata K. Tsunoda G. Hanazono 2008 Distribution of retinal responses evoked by transscleral electrical stimulation detected by intrinsic signal imaging in macaque monkeys Invest Ophthalmol Vis Sci 49 2193 2200
39. G. Hanazono K. Tsunoda Y. Kazato K. Tsubota M. Tanifuji 2008 Evaluating neural activity of retinal ganglion cells by flash-evoked intrinsic signal imaging in macaque retina Invest Ophthalmol Vis Sci 49 4655 4663
40. N. Wali L.E. Leguire 1992 The photopic hill: a new phenomenon of the light adapted electroretinogram Doc Ophthalmol 80 335 345
41. I.H. Wagman J. Waldman D. Naidoff L.B. Feinschil R. Cahan 1954 The recording of the electroretinogram in humans and in animals; investigation of retinal sensitivity following brief flashes of light Am J Ophthalmol 38 60 69
42. O.A. Mahroo T.D. Lamb 2004 Recovery of the human photopic electroretinogram after bleaching exposures: estimation of pigment regeneration kinetics J Physiol 554 417 437
43. R.S. Weinhaus J.M. Burke F.C. Delori D.M. Snodderly 1995 Comparison of fluorescein angiography with microvascular anatomy of macaque retinas Exp Eye Res 61 1 16
44. C. Roy C. Sherrington 1890 On the regulation of the blood supply of the brain J Physiol 11 85 108
45. A. Villringer U. Dirnagl 1995 Coupling of brain activity and cerebral blood flow: basis of functional neuroimaging Cerebrovasc Brain Metab Rev 7 240 276
46. K. Bizheva R. Pflug B. Hermann 2006 Optophysiology: depth-resolved probing of retinal physiology with functional ultrahigh-resolution optical coherence tomography Proc Natl Acad Sci U S A 103 5066 5071
47. W.W. Dawson G.L. Trick C.A. Litzkow 1979 Improved electrode for electroretinography Invest Ophthalmol Vis Sci 18 988 991
48. F. Gekeler A. Messias M. Ottinger K.U. Bartz-Schmidt E. Zrenner 2006 Phosphenes electrically evoked with DTL electrodes: a study in patients with retinitis pigmentosa, glaucoma, and homonymous visual field loss and normal subjects Invest Ophthalmol Vis Sci 47 4966 4974
49. D.R. Crapper W.K. Noell 1963 Retinal excitation and inhibition from direct electrical stimulation J Neurophysiol 26 924 947
50. R.W. Knighton 1975 An electrically evoked slow potential of the frog's retina. I. Properties of response J Neurophysiol 38 185 197
51. A. Stett W. Barth S. Weiss H. Haemmerle E. Zrenner 2000 Electrical multisite stimulation of the isolated chicken retina Vision Res 40 1785 1795
52. A. Kaneko T. Saito 1983 Ionic mechanisms underlying the responses of off-center bipolar cells in the carp retina. II. Studies on responses evoked by transretinal current stimulation J Gen Physiol 81 603 612 (Pubitemid 13130083)
53. J. Toyoda M. Fujimoto 1984 Application of transretinal current stimulation for the study of bipolar-amacrine transmission J Gen Physiol 84 915 925
54. K. Shimazu Y. Miyake S. Watanabe 1999 Retinal ganglion cell response properties in the transcorneal electrically evoked response of the visual system Vision Res 39 2251 2260
55. E. Margalit W.B. Thoreson 2006 Inner retinal mechanisms engaged by retinal electrical stimulation Invest Ophthalmol Vis Sci 47 2606 2612
56. A.L. Byzov J.A. Trifonov 1968 The response to electric stimulation of horizontal cells in the carp retina Vis Res 8 817 822
57. M. Murakami K. Takahashi 1987 Calcium action potential and its use for measurement of reversal potentials of horizontal cell responses in carp retina J Physiol 386 165 180
58. K. Takahashi M. Murakami 1988 Calcium action potential in ON-OFF transient amacrine cell of the carp retina Brain Res 456 29 37
59. L. Li Y. Hayashida T. Yagi 2005 Temporal properties of retinal ganglion cell responses to local transretinal current stimuli in the frog retina Vis Res 45 263 273
60. A.M. Potts J. Inoue D. Buffum 1968 The electrically evoked response of the visual system (EER) Invest Ophthalmol 7 269 278
61. A.M. Potts J. Inoue 1969 The electrically evoked response (EER) of the visual system. II. Effect of adaptation and retinitis pigmentosa Invest Ophthalmol 8 605 612
62. A.M. Potts J. Inoue 1970 The electrically evoked response of the visual system (EER). 3. Further contribution to the origin of the EER Invest Ophthalmol 9 814 819
63. Y. Miyake K. Yanagida K. Yagasaki 1980 Clinical application of EER (electrically evoked response). 1. Analysis of EER in normal subjects [in Japanese] Nippon Ganka Gakkai Zasshi 84 354 360 (Pubitemid 11241973)
64. Y. Miyake K. Yanagida K. Yagasaki 1980 Clinical application of EER (electrically evoked response). 2. Analysis of EER in patients with dysfunctional rod or cone visual pathway [in Japanese] Nippon Ganka Gakkai Zasshi 84 502 509 (Pubitemid 11237578)
65. Y. Miyake K. Yanagida K. Yagasaki 1980 Clinical application of EER (electrically evoked response). 3. Analysis of EER in patients with central retinal arterial occlusion [in Japanese] Nippon Ganka Gakkai Zasshi 84 587 593 (Pubitemid 10022805)
66. Y. Miyake K. Yanagida K. Yagasaki 1980 Clinical application of EER (electrically evoked response). Analysis of EER in patients with optic nerve disease [in Japanese] Nippon Ganka Gakkai Zasshi 84 2047 2052
67. G.S. Brindley 1955 The site of electrical excitation of the human eye J Physiol 127 189 200
68. V.V. Toi C.E. Riva 1994 Variations of blood flow at optic disc nerve head induced by sinusoidal flicker stimulation in cats J Physiol 482 189 202
69. B. Falsini C.E. Riva E. Logean 2002 Flicker-evoked changes in human optic nerve blood flow: relationship with retinal neural activity Invest Ophthalmol Vis Sci 43 2309 2316
70. C.E. Riva E. Logean B. Falsini 2004 Temporal dynamics and magnitude of the blood flow response at the optic disk in normal subjects during functional retinal flicker-stimulation Neurosci Lett 356 75 78
71. C.E. Riva T. Salgarello E. Logean A. Colotto E.M. Galan B. Falsini 2004 Flicker-evoked response measured at the optic disc rim is reduced in ocular hypertension and early glaucoma Invest Ophthalmol Vis Sci 45 3662 3668
72. D.H. Kelly 1961 Visual response to time-dependent stimuli. I. Amplitude sensitivity measurements J Opt Soc Am 51 422 429
73. J.W. Gebhard 1952 Thresholds of the human eye for electric stimulation by different wave forms J Exp Psychol 44 132 140
74. D. Regan 1968 A high frequency mechanism which underlies visual evoked potentials Electroencephalogr Clin Neurophysiol 25 231 237
75. T. Tanino S. Kato M. Kawasumi 1981 Studies on electrically evoked pupillary reflex-indirect reflex and its frequency characteristic Jpn J Ophthalmol 25 423 429
76. D. Malonek A. Grinvald 1996 Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping Science 272 551 554
77. N. Pouratian A. Toga 2002
78. E.S. Barriga M. Pattichis D. Ts'o 2007 Spatiotemporal independent component analysis for the detection of functional responses in cat retinal images IEEE Trans Med Imaging 26 1035 1045
79. M. Fukuda U.M. Rajagopalan R. Homma M. Matsumoto M. Nishizaki M. Tanifuji 2005 Localization of activity-dependent changes in blood volume to submillimeter-scale functional domains in cat visual cortex Cereb Cortex 15 823 833
80. A. Longo M. Geiser C.E. Riva 2000 Subfoveal choroidal blood flow in response to light-dark exposure Invest Ophthalmol Vis Sci 41 2678 2683
81. C.E. Riva S. Harino R.D. Shonat B.L. Petrig 1991 Flicker evoked increase in optic nerve head blood flow in anesthetized cats Neurosci Lett 128 291 296
82. C.E. Riva B. Falsini E. Logean 2001 Flicker-evoked responses of human optic nerve head blood flow: luminance versus chromatic modulation Invest Ophthalmol Vis Sci 42 756 762
83. S. Viswanathan L.J. Frishman J.G. Robson R.S. Harwerth E.L. Smith 3rd 1999 The photopic negative response of the macaque electroretinogram: reduction by experimental glaucoma Invest Ophthalmol Vis Sci 40 1124 1136
84. S. Viswanathan L.J. Frishman J.G. Robson J.W. Walters 2001 The photopic negative response of the flash electroretinogram in primary open angle glaucoma Invest Ophthalmol Vis Sci 42 514 522
85. T. Narahashi 1974 Chemicals as tools in the study of excitable membranes Physiol Rev 54 813 889
86. S.A. Bloomfield 1996 Effect of spike blockade on the receptive-field size of amacrine and ganglion cells in the rabbit retina J Neurophysiol 75 1878 1893
87. H.A. Quigley W.R. Green 1979 The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes Ophthalmology 86 1803 1830
88. H.A. Quigley E.M. Addicks W.R. Green 1982 Optic nerve damage in human glaucoma. III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy Arch Ophthalmol 100 135 146
89. H.A. Quigley G.R. Dunkelberger W.R. Green 1989 Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma Am J Ophthalmol 107 453 464
90. Y. Glovinsky H.A. Quigley G.R. Dunkelberger 1991 Retinal ganglion cell loss is size dependent in experimental glaucoma Invest Ophthalmol Vis Sci 32 484 491
91. L.J. Frishman F.F. Shen L. Du 1996 The scotopic electroretinogram of macaque after retinal ganglion cell loss from experimental glaucoma Invest Ophthalmol Vis Sci 37 125 141
92. L.A. Kerrigan-Baumrind H.A. Quigley M.E. Pease D.F. Kerrigan R.S. Mitchell 2000 Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons Invest Ophthalmol Vis Sci 41 741 748
93. J.T. Mcilwain 1964 Receptive fields of optic tract axons and lateral geniculate cells: peripheral extent and barbiturate sensitivity J Neurophysiol 27 1154 1173
94. J.T. Mcilwain 1966 Some evidence concerning physiological basis of periphery effect in cats retina Exp Brain Res 1 265 271
95. A.M. Derrington P. Lennie M.J. Wright 1979 Mechanism of peripherally evoked-responses in retinal ganglion-cells J Physiol 289 299 310
96. L.J. Toth S.C. Rao D.S. Kim D. Somers M. Sur 1996 Subthreshold facilitation and suppression in primary visual cortex revealed by intrinsic signal imaging Proc Natl Acad Sci U S A 93 9869 9874
97. E. Kaplan E. Benardete 2001 The dynamics of primate retinal ganglion cells Prog Brain Res 134 17 34
98. X.C. Yao Y.B. Zhao 2008 Optical dissection of stimulus-evoked retinal activation Opt Exp 16 12446 12459
99. Y.B. Zhao X.C. Yao 2008 Intrinsic optical imaging of stimulus-modulated physiological responses in amphibian retina Opt Lett 33 342 344
100. V.J. Srinivasan M. Wojtkowski J.G. Fujimoto J.S. Duker 2006 In vivo measurement of retinal physiology with high-speed ultrahigh-resolution optical coherence tomography Opt Lett 31 2308 2310 (Pubitemid 44391866)