Evaluating neural activity of retinal ganglion cells by flash-evoked intrinsic signal imaging in macaque retina

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 10, 2008, Pages 4655-4663

  Hanazono, Gen ^a,b,c   Tsunoda, Kazushige ^a,b   Kazato, Yoko ^a,b,d   Tsubota, Kazuo ^e   Tanifuji, Manabu ^b  

^a National Hospital Organization   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c Kikkoman General Hospital   (Japan)

^d NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TETRODOTOXIN; SODIUM CHANNEL BLOCKING AGENT;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DOPPLER FLOWMETRY; EVOKED VISUAL RESPONSE; IMAGING; INJECTION; INTRINSIC SIGNAL IMAGING; LIGHT; MACACA; MONKEY; NERVE CELL; NONHUMAN; OPTIC DISK; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA; RETINA BLOOD FLOW; RETINA FOVEA; RETINA GANGLION CELL; SPECTRAL SENSITIVITY; VISUAL CORTEX; ANIMAL; BLOOD FLOW; BLOOD FLOW VELOCITY; DRUG EFFECT; ELECTROCARDIOGRAPHY; ELECTROENCEPHALOGRAPHY; ELECTRORETINOGRAPHY; LASER DOPPLER FLOWMETRY; PHOTOSTIMULATION; PHOTOTRANSDUCTION; PHYSIOLOGY; RADIATION EXPOSURE; RETINA BLOOD VESSEL; VITREOUS BODY;

ANIMALS; BLOOD FLOW VELOCITY; ELECTROCARDIOGRAPHY; ELECTROENCEPHALOGRAPHY; ELECTRORETINOGRAPHY; INJECTIONS; LASER-DOPPLER FLOWMETRY; MACACA; MACACA MULATTA; NEURONS; PHOTIC STIMULATION; PHOTOTRANSDUCTION; REGIONAL BLOOD FLOW; RETINA; RETINAL GANGLION CELLS; RETINAL VESSELS; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; VISUAL CORTEX; VITREOUS BODY;

EID: 53449097926     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-1936     Document Type: Article

References (35)

1. Tsunoda K, Oguchi Y, Hanazono G, Tanifuji M. Mapping cone- and rod-induced retinal responsiveness in macaque retina by optical imaging. Invest Ophthalmol Vis Sci. 2004;45:3820-3826. (Pubitemid 39298602)
2. Hanazono G, Tsunoda K, Shinoda K, Tsubota K, Miyake Y, Tanifuji M. Intrinsic signal imaging in macaque retina reveals different types of flash-induced light reflectance changes of different origins. Invest Ophthalmol Vis Sci. 2007;48:2903-2912. (Pubitemid 351261248)
3. Inomata K, Tsunoda K, Hanazono G, et al. Distribution of retinal responses evoked by trans-scleral electrical stimulation detected by intrinsic signal imaging in macaque monkeys. Invest Ophthalmol Vis Sci. 2008;49:2193-2200.
4. Abramoff MD, Kwon YH, Ts'o D, et al. Visual stimulus-induced changes in human near-infrared fundus reflectance. Invest Ophthalmol Vis Sci. 2006;47:715-721. (Pubitemid 46768402)
5. Okawa Y, Fujikado T, Miyoshi T, et al. Optical imaging to evaluate retinal activation by electrical currents using suprachoroidal-transretinal stimulation. Invest Ophthalmol Vis Sci. 2007;48:4777-4784. (Pubitemid 351260998)
6. Duong TQ, Ngan SC, Ugurbil K, Kim SG. Functional magnetic resonance imaging of the retina. Invest Ophthalmol Vis Sci. 2002;43:1176-1181. (Pubitemid 34258290)
7. Cheng H, Nair G, Walker TA, et al. Structural and functional MRI reveals multiple retinal layers. Proc Natl Acad Sci U S A. 2006;103:17525-17530. (Pubitemid 44789002)
8. Bizheva K, Pflug R, Hermann B, et al. Optophysiology: depth-resolved probing of retinal physiology with functional ultrahighresolution optical coherence tomography. Proc Natl Acad Sci U S A. 2006;103:5066-5071.
9. Srinivasan VJ, Wojtkowski M, Fujimoto JG, Duker JS. In vivo measurement of retinal physiology with high-speed ultrahigh-resolution optical coherence tomography. Opt Lett. 2006;31:2308-2310. (Pubitemid 44391866)
10. Jonnal S, Rha J, Zhang Y, Cense B, Gao W, Miller D. In vivo functional imaging of human cone photoreceptors. Optics Express. 2007;15:16141-16159. (Pubitemid 350214428)
11. Zhang Y, Cense B, Rha J, et al. High-speed volumetric imaging of cone photoreceptors with adaptive optics spectral domain optical coherence tomography. Optics Express. 2006;14:4380-4394. (Pubitemid 43727628)
12. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80:389-393.
13. Quigley HA, Green WR. The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes. Ophthalmology. 1979;86:1803-1830.
14. Quigley HA, Addicks EM, Green WR. Optic nerve damage in human glaucoma, III: quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy. Arch Ophthalmol. 1982;100:135-146.
15. Quigley HA, Dunkelberger GR, Green WR. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol. 1989;107:453-464.
16. Bonhoeffer T, Grinvald A. Optical imaging based on intrinsic signals: the methodology. In: Toga AW, Mazziotta JC, eds. Brain Mapping. San Diego: Academic Press; 1996:55-97.
17. Tsunoda K, Yamane Y, Nishizaki M, Tanifuji M. Complex objects are represented in macaque inferotemporal cortex by the combination of feature columns. Nat Neurosci. 2001;4:832-838. (Pubitemid 32702516)
18. Viswanathan S, Frishman LJ, Robson JG, Harwerth RS, Smith EL 3rd. The photopic negative response of the macaque electroretinogram: reduction by experimental glaucoma. Invest Ophthalmol Vis Sci. 1999;40:1124-1136. (Pubitemid 29211449)
19. Viswanathan S, Frishman LJ, Robson JG, Walters JW. The photopic negative response of the flash electroretinogram in primary open angle glaucoma. Invest Ophthalmol Vis Sci. 2001;42:514-522. (Pubitemid 32121488)
20. Fukuda M, Rajagopalan UM, Homma R, Matsumoto M, Nishizaki M, Tanifuji M. Localization of activity-dependent changes in blood volume to submillimeter-scale functional domains in cat visual cortex. Cereb Cortex. 2005;15:823-833. (Pubitemid 40696121)
21. Riva CE, Harino S, Shonat RD, Petrig BL. Flicker evoked increase in optic nerve head blood flow in anesthetized cats. Neurosci Lett. 1991;128:291-296.
22. Riva CE, Logean E, Falsini B. Temporal dynamics and magnitude of the blood flow response at the optic disk in normal subjects during functional retinal flicker-stimulation. Neurosci Lett. 2004;356:75-78. (Pubitemid 38121472)
23. Riva CE, Falsini B, Logean E. Flicker-evoked responses of human optic nerve head blood flow: luminance versus chromatic modulation. Invest Ophthalmol Vis Sci. 2001;42:756-762. (Pubitemid 32206919)
24. Riva CE, Salgarello T, Logean E, Colotto A, Galan EM, Falsini B. Flicker-evoked response measured at the optic disc rim is reduced in ocular hypertension and early glaucoma. Invest Ophthalmol Vis Sci. 2004;45:3662-3668. (Pubitemid 39298584)
25. Narahashi T. Chemicals as tools in the study of excitable membranes. Physiol Rev. 1974;54:813-889.
26. Bloomfield SA. Effect of spike blockade on the receptive-field size of amacrine and ganglion cells in the rabbit retina. J Neurophysiol. 1996;75:1878-1893.
27. Glovinsky Y, Quigley HA, Dunkelberger GR. Retinal ganglion cell loss is size dependent in experimental glaucoma. Invest Ophthalmol Vis Sci. 1991;32:484-491. (Pubitemid 23072874)
28. Frishman LJ, Shen FF, Du L, et al. The scotopic electroretinogram of macaque after retinal ganglion cell loss from experimental glaucoma. Invest Ophthalmol Vis Sci. 1996;37:125-141. (Pubitemid 26036524)
29. Kerrigan-Baumrind LA, Quigley HA, Pease ME, Kerrigan DF, Mitchell RS. Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Invest Ophthalmol Vis Sci. 2000;41:741-748.
30. Sutter EE, Bearse MA Jr. The optic nerve head component of the human ERG. Vision Res. 1999;39:419-436. (Pubitemid 29051470)
31. Hood DC, Bearse MA Jr, Sutter EE, Viswanathan S, Frishman LJ. The optic nerve head component of the monkey's (Macaca mulatta) multifocal electroretinogram (mERg). Vision Res. 2001;41:2029-2041. (Pubitemid 32525759)
32. Kurtenbach A, Leo-Kottler B, Zrenner E. Inner retinal contributions to the multifocal electroretinogram: patients with Leber's hereditary optic neuropathy (LHON): multifocal ERG in patients with LHON. Doc Ophthalmol. 2004;108:231-240.
33. Buerk DG, Riva CE, Cranstoun SD. Nitric oxide has a vasodilatory role in cat optic nerve head during flicker stimuli. Microvasc Res. 1996;52:13-26.
34. Kondo M, Wang L, Bill A. The role of nitric oxide in hyperaemic response to flicker in the retina and optic nerve in cats. Acta Ophthalmol Scand. 1997;75:232-235. (Pubitemid 27315582)
35. Peppiatt CM, Howarth C, Mobbs P, Attwell D. Bidirectional control of CNS capillary diameter by pericytes. Nature. 2006;443:700-704. (Pubitemid 44564713)