메뉴 건너뛰기




Volumn 66, Issue 18, 2009, Pages 1645-1651

Effect of the ABCB1 3435C>T polymorphism on tacrolimus concentrations and dosage requirements in liver transplant recipients

Author keywords

Blood levels; Dosage; Immunosuppressive agents; Mycophenolate mofetil; Pharmacokinetics; Polymorphisms; Steroids, cortico; Tacrolimus; Transplantation

Indexed keywords

CORTICOSTEROID; GLYCOPROTEIN P; METHYLPREDNISOLONE; MULTIDRUG RESISTANCE PROTEIN 1; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

EID: 70349304415     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp080396     Document Type: Article
Times cited : (9)

References (36)
  • 1
    • 0343416856 scopus 로고    scopus 로고
    • Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery
    • Hebert MF. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv Drug Deliv Rev. 1997; 27:201-214
    • (1997) Adv Drug Deliv Rev , vol.27 , pp. 201-214
    • Hebert, M.F.1
  • 2
    • 34248996167 scopus 로고    scopus 로고
    • Polymorphisms of multidrug resistance gene (MDR1) and cyclosporine absorption in de novo renal transplant patients
    • DOI 10.1097/01.tp.0000264197.88129.2e, PII 0000789020070527000015
    • Foote CJ, Greer W, Kiberd B et al. Polymorphisms of multidrug resistance gene (MDR1) and cyclosporine absorption in de novo renal transplant patients. Transplantation. 2007; 83:1380-1384 (Pubitemid 46800316)
    • (2007) Transplantation , vol.83 , Issue.10 , pp. 1380-1384
    • Foote, C.J.1    Greer, W.2    Kiberd, B.3    Fraser, A.4    Lawen, J.5    Nashan, B.6    Belitsky, P.7
  • 4
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. N Engl J Med. 2003; 348:538-549
    • (2003) N Engl J Med , vol.348 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 5
    • 0027945930 scopus 로고
    • Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA)
    • Gonschior A, Christians U, Braun F et al. Measurement of blood concentrations of FK 506 (tacrolimus) and its metabolites in seven liver graft patients after first dose by HPLC-MS and microparticulate enzyme immunoassay (MEIA). Br J Clin Pharmacol. 1994; 38:567-571 (Pubitemid 24365865)
    • (1994) British Journal of Clinical Pharmacology , vol.38 , Issue.6 , pp. 567-571
    • Gonschior, A.-K.1    Christians, U.2    Braun, F.3    Winkler, M.4    Linck, A.5    Baumann, J.6    Sewing -Fr, K.7
  • 6
    • 0028917496 scopus 로고
    • Pharmacokinetics of tacrolimus in liver transplant patients
    • Jusko WJ, Piekoszewski W, Klintmalm GB et al. Pharmacokinetics of tacrolimus in liver transplant patients. Clin Pharmacol Ther. 1995; 57:281-290
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 281-290
    • Jusko, W.J.1    Piekoszewski, W.2    Klintmalm, G.B.3
  • 7
    • 0035993643 scopus 로고    scopus 로고
    • Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation
    • DOI 10.1016/S0041-1345(02)03013-0, PII S0041134502030130
    • Böttiger Y, Undre NA, Säwe J et al. Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation. Transplant Proc. 2002; 34:1544-1555 (Pubitemid 34895224)
    • (2002) Transplantation Proceedings , vol.34 , Issue.5 , pp. 1544-1545
    • Bottiger, Y.1    Undre, N.A.2    Sawe, J.3    Stevenson, P.J.4    Ericzon, B.G.5
  • 8
    • 0032986187 scopus 로고    scopus 로고
    • Low systemic exposure to tacrolimus correlates with acute rejection
    • Undre NA, van Hooff J, Christiaans M et al. Low systemic exposure to tacrolimus correlates with acute rejection. Transplant Proc. 1999; 31:296-298
    • (1999) Transplant Proc , vol.31 , pp. 296-298
    • Undre, N.A.1    Van Hooff, J.2    Christiaans, M.3
  • 11
    • 34548640104 scopus 로고    scopus 로고
    • Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients
    • DOI 10.1111/j.1365-2710.2007.00850.x
    • Li D, Lu W, Zhu JY et al. Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients. J Clin Pharm Ther. 2007; 32:505-15. (Pubitemid 47404287)
    • (2007) Journal of Clinical Pharmacy and Therapeutics , vol.32 , Issue.5 , pp. 505-515
    • Li, D.1    Lu, W.2    Zhu, J.-Y.3    Gao, J.4    Lou, Y.-Q.5    Zhang, G.-L.6
  • 12
    • 42149176588 scopus 로고    scopus 로고
    • Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients
    • Fukudo M, Yano I, Yoshimura A et al. Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients. Pharmacogenet Genomics. 2008; 18:413-423
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 413-423
    • Fukudo, M.1    Yano, I.2    Yoshimura, A.3
  • 13
    • 3242779991 scopus 로고    scopus 로고
    • CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation
    • DOI 10.1097/01.fpc.0000114747.08559.49
    • Goto M, Masuda S, Kiuchi T et al. CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation. Pharmacogenetics. 2004; 14:471-478 (Pubitemid 38971237)
    • (2004) Pharmacogenetics , vol.14 , Issue.7 , pp. 471-478
    • Goto, M.1    Masuda, S.2    Kiuchi, T.3    Ogura, Y.4    Oike, F.5    Okuda, M.6    Tanaka, K.7    Inui, K.-I.8
  • 14
    • 0036667953 scopus 로고    scopus 로고
    • C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation
    • DOI 10.1097/00008571-200208000-00005
    • Goto M, Masuda S, Saito H et al. 3435C>T polymorphism in the gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation. Pharmacogenetics. 2002; 12:451-457 (Pubitemid 34913527)
    • (2002) Pharmacogenetics , vol.12 , Issue.6 , pp. 451-457
    • Goto, M.1    Masuda, S.2    Saito, H.3    Uemoto, S.4    Kiuchi, T.5    Tanaka, K.6    Inui, K.-I.7
  • 15
    • 33646439263 scopus 로고    scopus 로고
    • Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients
    • Wei-lin W, Jing J, Shu-sen Z et al. Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients. Liver Transpl. 2006; 12:775-780
    • (2006) Liver Transpl , vol.12 , pp. 775-780
    • Wei-lin, W.1    Jing, J.2    Shu-sen, Z.3
  • 16
    • 0033996572 scopus 로고    scopus 로고
    • Update of the international Banff schema for liver allograft rejection: Working recommendations for the histopathologic staging and reporting of chronic rejection. An international panel
    • Demetris A, Adams D, Bellamy C et al. Update of the international Banff schema for liver allograft rejection: working recommendations for the histopathologic staging and reporting of chronic rejection. An international panel. Hepatology. 2000; 31:792-799
    • (2000) Hepatology , vol.31 , pp. 792-799
    • Demetris, A.1    Adams, D.2    Bellamy, C.3
  • 17
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976; 16:31-41.
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 18
    • 42149136030 scopus 로고    scopus 로고
    • Biotransformation enzymes and drug transporters pharmacogenetics in relation to immunosuppressive drugs: Impact on pharmacokinetics and clinical outcome
    • Mourad M, Wallemacq P, De Meyer M et al. Biotransformation enzymes and drug transporters pharmacogenetics in relation to immunosuppressive drugs: impact on pharmacokinetics and clinical outcome. Transplantation. 2008; 85(suppl 7):S19-24.
    • (2008) Transplantation , vol.85 , Issue.SUPPL. 7
    • Mourad, M.1    Wallemacq, P.2    De Meyer, M.3
  • 19
    • 0037307357 scopus 로고    scopus 로고
    • Frequency distribution of 3435C>T mutation in exon 26 of the gene in a Spanish population
    • Bernal ML, Sinues B, Fanlo A et al. Frequency distribution of 3435C>T mutation in exon 26 of the gene in a Spanish population. Ther Drug Monit. 2003; 25:107-111
    • (2003) Ther Drug Monit , vol.25 , pp. 107-111
    • Bernal, M.L.1    Sinues, B.2    Fanlo, A.3
  • 20
    • 3142734959 scopus 로고    scopus 로고
    • MDR1 3435C>T polymorphism influences cyclosporin a dose requirement in liver-transplant recipients
    • Bonhomme-Faivre L, Devocelle A, Saliba F et al. MDR1 3435C>T polymorphism influences cyclosporin A dose requirement in liver-transplant recipients. Transplantation. 2004; 78:21-25
    • (2004) Transplantation , vol.78 , pp. 21-25
    • Bonhomme-Faivre, L.1    Devocelle, A.2    Saliba, F.3
  • 22
    • 34648857526 scopus 로고    scopus 로고
    • 1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation
    • DOI 10.1097/FPC.0b013e3282e9a533, PII 0121301120071000000010
    • Elens L, Capron A, Kerckhove VV et al. 1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation. Pharmacogenet Genomics. 2007; 17:873-883 (Pubitemid 47462301)
    • (2007) Pharmacogenetics and Genomics , vol.17 , Issue.10 , pp. 873-883
    • Elens, L.1    Capron, A.2    Kerckhove, V.V.3    Lerut, J.4    Mourad, M.5    Lison, D.6    Wallemacq, P.7    Haufroid, V.8
  • 23
    • 4344656740 scopus 로고    scopus 로고
    • CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus
    • DOI 10.1111/j.1600-6143.2004.00539.x
    • Lemahieu WP, Maes BD, Verbeke K et al. CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporine vs. tacrolimus vs. sirolimus. Am J Transplant. 2004; 4:1514-1522 (Pubitemid 39159067)
    • (2004) American Journal of Transplantation , vol.4 , Issue.9 , pp. 1514-1522
    • Lemahieu, W.P.D.1    Maes, B.D.2    Verbeke, K.3    Vanrenterghem, Y.4
  • 24
    • 27844525007 scopus 로고    scopus 로고
    • Combined therapy with atorvastatin and calcineurin inhibitors: No interactions with tacrolimus
    • Lemahieu WP, Hermann M, Asberg A et al. Combined therapy with atorvastatin and calcineurin inhibitors: no interactions with tacrolimus. Am J Transplant. 2005; 5:2236-2243
    • (2005) Am J Transplant , vol.5 , pp. 2236-2243
    • Lemahieu, W.P.1    Hermann, M.2    Asberg, A.3
  • 26
    • 0031742968 scopus 로고    scopus 로고
    • Brain bilirubin content in P-glycoprotein-deficient transgenic null mutant mice
    • Watchko JF, Daood MJ, Hansen TW. Brain bilirubin content in P-glycoprotein-deficient transgenic null mutant mice. Pediatr Res. 1998; 44:763-766
    • (1998) Pediatr Res , vol.44 , pp. 763-766
    • Watchko, J.F.1    Daood, M.J.2    Hansen, T.W.3
  • 27
    • 0035680722 scopus 로고    scopus 로고
    • P-glycoprotein and bilirubin disposition
    • Watchko JF, Daood MJ, Mahmood B et al. P-glycoprotein and bilirubin disposition. J Perinatol. 2001; 21(suppl 1):S43-7.
    • (2001) J Perinatol , vol.21 , Issue.SUPPL. 1
    • Watchko, J.F.1    Daood, M.J.2    Mahmood, B.3
  • 28
    • 0035186907 scopus 로고    scopus 로고
    • Factors affecting the pharmacokinetics of tacrolimus (FK506) in hematopoietic cell transplant (HCT) patients
    • Jacobson P, Ng J, Ratanatharathorn V et al. Factors affecting the pharmacokinetics of tacrolimus (FK506) in hematopoietic cell transplant (HCT) patients. Bone Marrow Transplant. 2001; 28:753-758
    • (2001) Bone Marrow Transplant , vol.28 , pp. 753-758
    • Jacobson, P.1    Ng, J.2    Ratanatharathorn, V.3
  • 30
    • 1542373607 scopus 로고    scopus 로고
    • Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors
    • DOI 10.1097/00008571-200311000-00002
    • Hebert MF, Dowling AL, Gierwatowski C et al. Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors. Pharmacogenetics. 2003; 13:661-674 (Pubitemid 38316510)
    • (2003) Pharmacogenetics , vol.13 , Issue.11 , pp. 661-674
    • Hebert, M.F.1    Dowling, A.L.S.2    Gierwatowski, C.3    Lin, Y.S.4    Edwards, K.L.5    Davis, C.L.6    Marsh, C.L.7    Schuetz, E.G.8    Thummel, K.E.9
  • 31
    • 0037115210 scopus 로고    scopus 로고
    • Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome P4503a5 and P-glycoprotein correlate with dose requirement
    • DOI 10.1097/00007890-200212150-00002
    • Macphee IA, Fredericks S, Tai T et al. Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement. Transplantation. 2002; 74:1486-1489 (Pubitemid 36014218)
    • (2002) Transplantation , vol.74 , Issue.11 , pp. 1486-1489
    • Macphee, I.A.M.1    Fredericks, S.2    Tai, T.3    Syrris, P.4    Carter, N.D.5    Johnston, A.6    Goldberg, L.7    Holt, D.W.8
  • 32
    • 33745187536 scopus 로고    scopus 로고
    • The Effect of MDR1 (ABCB1) Polymorphism on the Pharmacokinetic of Tacrolimus in Turkish Renal Transplant Recipients
    • DOI 10.1016/j.transproceed.2006.02.079, PII S0041134506001692
    • Akbas SH, Bilgen T, Keser I et al. The effect of (ABCB1) polymorphism on the pharmacokinetics of tacrolimus in Turkish renal transplant recipients. Transpl Proc. 2006; 38:1290-1292 (Pubitemid 43912729)
    • (2006) Transplantation Proceedings , vol.38 , Issue.5 , pp. 1290-1292
    • Akbas, S.H.1    Bilgen, T.2    Keser, I.3    Tuncer, M.4    Yucetin, L.5    Tosun, O.6    Gultekin, M.7    Luleci, G.8
  • 34
    • 33748710224 scopus 로고    scopus 로고
    • Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements
    • DOI 10.1097/01.tp.0000234942.78716.c0, PII 0000789020060915000017
    • Fredericks S, Moreton M, Reboux S et al. Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements. Transplantation. 2006; 82:705-708 (Pubitemid 44395243)
    • (2006) Transplantation , vol.82 , Issue.5 , pp. 705-708
    • Fredericks, S.1    Moreton, M.2    Reboux, S.3    Carter, N.D.4    Goldberg, L.5    Holt, D.W.6    MacPhee, I.A.M.7
  • 35
    • 20344379217 scopus 로고    scopus 로고
    • Initial dosage adjustment for oral administration of tacrolimus using the intestinal MDR1 level in living-donor liver transplant recipients
    • DOI 10.1016/j.transproceed.2005.02.081, PII S0041134505001983
    • Masuda S, Goto M, Okuda M et al. Initial dosage adjustment for oral administration of tacrolimus using the intestinal level in living-donor liver transplant recipients. Transpl Proc. 2005; 37:1728-1729 (Pubitemid 40790811)
    • (2005) Transplantation Proceedings , vol.37 , Issue.4 , pp. 1728-1729
    • Masuda, S.1    Goto, M.2    Okuda, M.3    Ogura, Y.4    Oike, F.5    Kiuchi, T.6    Tanaka, K.7    Inui, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.