Drug release from MCC- and carrageenan-based pellets: Experiment and theory

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 73, Issue 2, 2009, Pages 302-309

  Kranz, H ^a   Jurgens K ^a   Pinier, M ^a   Siepmann, J ^b  

^a BAYER PHARMA AG   (Germany)

^b UNIV LILLE   (France)

Author keywords

Carrageenan; Extrusion spheronisation; Microcrystalline cellulose; Pellets; Release mechanisms

Indexed keywords

3 [5 CHLORO 2 [2 [4 (4 FLUOROBENZYL) 2 METHYLPIPERAZIN 1 YL] 2 OXOETHOXY]PHENYL]URONIUM HYDROGEN SULFATE; CARRAGEENAN; CHEMOKINE RECEPTOR ANTAGONIST; CROSCARMELLOSE SODIUM; MACROGOL 6000; MICROCRYSTALLINE CELLULOSE; THEOPHYLLINE; UNCLASSIFIED DRUG; VATALANIB;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG PELLET; DRUG RELEASE; DRUG SOLUBILITY; PELLET EXTRUSION; POROSITY; SCANNING ELECTRON MICROSCOPY; SPHERONIZATION; SUSTAINED DRUG RELEASE; TENSILE STRENGTH;

CARBOXYMETHYLCELLULOSE SODIUM; CARRAGEENAN; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG COMPOUNDING; KINETICS; MODELS, CHEMICAL; PHTHALAZINES; POLYETHYLENE GLYCOLS; POROSITY; PYRIDINES; SOLUBILITY; THEOPHYLLINE;

EID: 70349303798     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.05.007     Document Type: Article

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