Pectinic acid, a novel excipient for production of pellets by extrusion/spheronisation: Preliminary studies

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 54, Issue 1, 2002, Pages 95-99

  Tho, Ingunn ^a   Sande, Sverre Arne ^a   Kleinebudde, Peter ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Dissolution profiles; Extrusion spheronisation; Image analysis; Pectinic acid; Pellets

Indexed keywords

GRANULAC 200; LACTOSE; PECTIN; PECTINIC ACID; RIBOFLAVIN; UNCLASSIFIED DRUG; EXCIPIENT; MICROSPHERE;

ARTICLE; CHEMICAL REACTION; DRUG FORMULATION; DRUG MANUFACTURE; DRUG PELLET; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; INTESTINE FLUID; METHODOLOGY; MODEL; PELLET EXTRUSION; PH; SIMULATION; SPHERONIZATION; STOMACH ACID; CHEMISTRY;

CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; MICROSPHERES; PECTINS; SUPPORT, NON-U.S. GOV'T;

EID: 0035985902     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00048-6     Document Type: Article

References (10)

1. Application of low substituted hydroxypropylcellulose (L-HPC) in the production of pellets using extrusion/spheronization
2. Avicel RC-591/chitosan beads by extrusion-spheronization technology
3. Effect of common classes of excipients on extrusion-spheronization
4. Waxy corn starch: A potent cofiller in pellets produced by extrusion-spheronization
5. Formulation of ranitidine pellets by extrusion spheronization with little or no microcrystalline cellulose
6. Extrusion/spheronisation of pectin based formulations
7. Extrusion/spheronisation of pectin based formulations
8. The strength of microcrystalline cellulose pellets - The effect of granulating with water ethanol mixtures
9. Drug solubility effects on predicting optimum conditions for extrusion and spheronization of pellets