Properties of pellets manufactured by wet extrusion/spheronization process using κ-carrageenan: Effect of process parameters

AAPS PharmSciTech

Volumn 8, Issue 4, 2007, Pages

  Thommes, Markus ^a   Kleinebudde, Peter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Carrageenan; Experimental design; Extrusion; Pellets; Process parameters; Spheronization

Indexed keywords

CARRAGEENAN; CHLORAMPHENICOL; DIMENHYDRINATE; GELLING AGENT; LIDOCAINE; PHENACETIN; SODIUM ION; DRUG; EXCIPIENT; WATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG MIXTURE; DRUG RELEASE; FACTORIAL ANALYSIS; HUMIDITY; PELLET EXTRUSION; SPHERONIZATION; TEMPERATURE; TENSILE STRENGTH; WATER CONTENT; CHEMISTRY; DRUG DOSAGE FORM; DRUG STABILITY; EVALUATION; KINETICS; METHODOLOGY; PARTICLE SIZE; PH; PHARMACEUTICS; SOLUBILITY; STATISTICAL MODEL;

CARRAGEENAN; CHEMISTRY, PHARMACEUTICAL; CHLORAMPHENICOL; DIMENHYDRINATE; DOSAGE FORMS; DRUG STABILITY; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; KINETICS; LIDOCAINE; MODELS, STATISTICAL; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; PHENACETIN; RESEARCH DESIGN; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TENSILE STRENGTH; WATER;

EID: 36849030685     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0804095     Document Type: Article

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