-
1
-
-
0036889329
-
Cell-free replication of the hepatitis C virus subgenomic replicon
-
Ali N., Tardif K.D., and Siddiqui A. Cell-free replication of the hepatitis C virus subgenomic replicon. J. Virol. 76 23 (2002) 12001-12007
-
(2002)
J. Virol.
, vol.76
, Issue.23
, pp. 12001-12007
-
-
Ali, N.1
Tardif, K.D.2
Siddiqui, A.3
-
2
-
-
0030955346
-
Epidemiology of hepatitis C
-
Alter M.J. Epidemiology of hepatitis C. Hepatology 26 3 Suppl. 1 (1997) 62S-65S
-
(1997)
Hepatology
, vol.26
, Issue.3 SUPPL. 1
-
-
Alter, M.J.1
-
3
-
-
66149128094
-
Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication
-
Berger K.L., Cooper J.D., Heaton N.S., Yoon R., Oakland T.E., Jordan T.X., Mateu G., Grakoui A., and Randall G. Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication. Proc. Natl. Acad. Sci. U. S. A. 106 18 (2009) 7577-7582
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.18
, pp. 7577-7582
-
-
Berger, K.L.1
Cooper, J.D.2
Heaton, N.S.3
Yoon, R.4
Oakland, T.E.5
Jordan, T.X.6
Mateu, G.7
Grakoui, A.8
Randall, G.9
-
4
-
-
0036893332
-
Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
-
Blight K.J., McKeating J.A., and Rice C.M. Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J. Virol. 76 24 (2002) 13001-13014
-
(2002)
J. Virol.
, vol.76
, Issue.24
, pp. 13001-13014
-
-
Blight, K.J.1
McKeating, J.A.2
Rice, C.M.3
-
5
-
-
0036100578
-
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
-
Egger D., Wolk B., Gosert R., Bianchi L., Blum H.E., Moradpour D., and Bienz K. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76 12 (2002) 5974-5984
-
(2002)
J. Virol.
, vol.76
, Issue.12
, pp. 5974-5984
-
-
Egger, D.1
Wolk, B.2
Gosert, R.3
Bianchi, L.4
Blum, H.E.5
Moradpour, D.6
Bienz, K.7
-
6
-
-
4644222500
-
A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication
-
Einav S., Elazar M., Danieli T., and Glenn J.S. A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication. J. Virol. 78 20 (2004) 11288-11295
-
(2004)
J. Virol.
, vol.78
, Issue.20
, pp. 11288-11295
-
-
Einav, S.1
Elazar, M.2
Danieli, T.3
Glenn, J.S.4
-
7
-
-
51349138269
-
Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis
-
Einav S., Gerber D., Bryson P.D., Sklan E.H., Elazar M., Maerkl S.J., Glenn J.S., and Quake S.R. Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis. Nat. Biotechnol. 26 9 (2008) 1019-1027
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.9
, pp. 1019-1027
-
-
Einav, S.1
Gerber, D.2
Bryson, P.D.3
Sklan, E.H.4
Elazar, M.5
Maerkl, S.J.6
Glenn, J.S.7
Quake, S.R.8
-
8
-
-
40949100394
-
The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection
-
Einav S., Sklan E.H., Moon H.M., Gehrig E., Liu P., Hao Y., Lowe A.W., and Glenn J.S. The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection. Hepatology 47 3 (2008) 827-835
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 827-835
-
-
Einav, S.1
Sklan, E.H.2
Moon, H.M.3
Gehrig, E.4
Liu, P.5
Hao, Y.6
Lowe, A.W.7
Glenn, J.S.8
-
9
-
-
4644281168
-
An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication
-
Elazar M., Liu P., Rice C.M., and Glenn J.S. An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication. J. Virol. 78 20 (2004) 11393-11400
-
(2004)
J. Virol.
, vol.78
, Issue.20
, pp. 11393-11400
-
-
Elazar, M.1
Liu, P.2
Rice, C.M.3
Glenn, J.S.4
-
10
-
-
0141507081
-
Replication of hepatitis C virus RNA occurs in a membrane-bound replication complex containing nonstructural viral proteins and RNA
-
El-Hage N., and Luo G. Replication of hepatitis C virus RNA occurs in a membrane-bound replication complex containing nonstructural viral proteins and RNA. J. Gen. Virol. 84 Pt 10 (2003) 2761-2769
-
(2003)
J. Gen. Virol.
, vol.84
, Issue.PART 10
, pp. 2761-2769
-
-
El-Hage, N.1
Luo, G.2
-
11
-
-
0345144016
-
Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
-
Gosert R., Egger D., Lohmann V., Bartenschlager R., Blum H.E., Bienz K., and Moradpour D. Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J. Virol. 77 9 (2003) 5487-5492
-
(2003)
J. Virol.
, vol.77
, Issue.9
, pp. 5487-5492
-
-
Gosert, R.1
Egger, D.2
Lohmann, V.3
Bartenschlager, R.4
Blum, H.E.5
Bienz, K.6
Moradpour, D.7
-
12
-
-
66149132203
-
Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B
-
Gouttenoire J., Castet V., Montserret R., Arora N., Raussens V., Ruysschaert J.M., Diesis E., Blum H.E., Penin F., and Moradpour D. Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B. J. Virol. 83 12 (2009) 6257-6268
-
(2009)
J. Virol.
, vol.83
, Issue.12
, pp. 6257-6268
-
-
Gouttenoire, J.1
Castet, V.2
Montserret, R.3
Arora, N.4
Raussens, V.5
Ruysschaert, J.M.6
Diesis, E.7
Blum, H.E.8
Penin, F.9
Moradpour, D.10
-
13
-
-
0242624460
-
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein
-
Hugle T., Fehrmann F., Bieck E., Kohara M., Krausslich H.G., Rice C.M., Blum H.E., and Moradpour D. The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein. Virology 284 1 (2001) 70-81
-
(2001)
Virology
, vol.284
, Issue.1
, pp. 70-81
-
-
Hugle, T.1
Fehrmann, F.2
Bieck, E.3
Kohara, M.4
Krausslich, H.G.5
Rice, C.M.6
Blum, H.E.7
Moradpour, D.8
-
14
-
-
0032489233
-
Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus
-
Ishido S., Fujita T., and Hotta H. Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus. Biochem. Biophys. Res. Commun. 244 1 (1998) 35-40
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.244
, Issue.1
, pp. 35-40
-
-
Ishido, S.1
Fujita, T.2
Hotta, H.3
-
15
-
-
60049083503
-
The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus
-
Jones D.M., Patel A.H., Targett-Adams P., and McLauchlan J. The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus. J. Virol. 83 5 (2009) 2163-2177
-
(2009)
J. Virol.
, vol.83
, Issue.5
, pp. 2163-2177
-
-
Jones, D.M.1
Patel, A.H.2
Targett-Adams, P.3
McLauchlan, J.4
-
16
-
-
17044411795
-
Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter
-
Kadoya H., Nagano-Fujii M., Deng L., Nakazono N., and Hotta H. Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter. Microbiol. Immunol. 49 3 (2005) 265-273
-
(2005)
Microbiol. Immunol.
, vol.49
, Issue.3
, pp. 265-273
-
-
Kadoya, H.1
Nagano-Fujii, M.2
Deng, L.3
Nakazono, N.4
Hotta, H.5
-
17
-
-
0025685188
-
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis
-
Kato N., Hijikata M., Ootsuyama Y., Nakagawa M., Ohkoshi S., Sugimura T., and Shimotohno K. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc. Natl. Acad. Sci. U. S. A. 87 24 (1990) 9524-9528
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, Issue.24
, pp. 9524-9528
-
-
Kato, N.1
Hijikata, M.2
Ootsuyama, Y.3
Nakagawa, M.4
Ohkoshi, S.5
Sugimura, T.6
Shimotohno, K.7
-
18
-
-
0036139053
-
Hepatitis C virus NS4A and NS4B proteins suppress translation in vivo
-
Kato J., Kato N., Yoshida H., Ono-Nita S.K., Shiratori Y., and Omata M. Hepatitis C virus NS4A and NS4B proteins suppress translation in vivo. J. Med. Virol. 66 2 (2002) 187-199
-
(2002)
J. Med. Virol.
, vol.66
, Issue.2
, pp. 187-199
-
-
Kato, J.1
Kato, N.2
Yoshida, H.3
Ono-Nita, S.K.4
Shiratori, Y.5
Omata, M.6
-
19
-
-
0032837572
-
Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B
-
Koch J.O., and Bartenschlager R. Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B. J. Virol. 73 9 (1999) 7138-7146
-
(1999)
J. Virol.
, vol.73
, Issue.9
, pp. 7138-7146
-
-
Koch, J.O.1
Bartenschlager, R.2
-
20
-
-
0037744869
-
Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus
-
Konan K.V., Giddings Jr. T.H., Ikeda M., Li K., Lemon S.M., and Kirkegaard K. Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus. J. Virol. 77 14 (2003) 7843-7855
-
(2003)
J. Virol.
, vol.77
, Issue.14
, pp. 7843-7855
-
-
Konan, K.V.1
Giddings Jr., T.H.2
Ikeda, M.3
Li, K.4
Lemon, S.M.5
Kirkegaard, K.6
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 259 (1970) 680-685
-
(1970)
Nature
, vol.227
, Issue.259
, pp. 680-685
-
-
Laemmli, U.K.1
-
22
-
-
67650735846
-
Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain
-
Liefhebber J.M., Brandt B.W., Broer R., Spaan W.J., and van Leeuwen H.C. Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain. Virol. J. 6 1 (2009) 62
-
(2009)
Virol. J.
, vol.6
, Issue.1
, pp. 62
-
-
Liefhebber, J.M.1
Brandt, B.W.2
Broer, R.3
Spaan, W.J.4
van Leeuwen, H.C.5
-
23
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann V., Korner F., Koch J., Herian U., Theilmann L., and Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285 5424 (1999) 110-113
-
(1999)
Science
, vol.285
, Issue.5424
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
24
-
-
0344373790
-
Topology of the membrane-associated hepatitis C virus protein NS4B
-
Lundin M., Monne M., Widell A., Von Heijne G., and Persson M.A. Topology of the membrane-associated hepatitis C virus protein NS4B. J. Virol. 77 9 (2003) 5428-5438
-
(2003)
J. Virol.
, vol.77
, Issue.9
, pp. 5428-5438
-
-
Lundin, M.1
Monne, M.2
Widell, A.3
Von Heijne, G.4
Persson, M.A.5
-
25
-
-
33750249579
-
Dual topology of the processed hepatitis C virus protein NS4B is influenced by the NS5A protein
-
Lundin M., Lindstrom H., Gronwall C., and Persson M.A. Dual topology of the processed hepatitis C virus protein NS4B is influenced by the NS5A protein. J. Gen. Virol. 87 Pt 11 (2006) 3263-3272
-
(2006)
J. Gen. Virol.
, vol.87
, Issue.PART 11
, pp. 3263-3272
-
-
Lundin, M.1
Lindstrom, H.2
Gronwall, C.3
Persson, M.A.4
-
26
-
-
0025249362
-
Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups
-
Miller R.H., and Purcell R.H. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc. Natl. Acad. Sci. U. S. A. 87 6 (1990) 2057-2061
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, Issue.6
, pp. 2057-2061
-
-
Miller, R.H.1
Purcell, R.H.2
-
27
-
-
3142764760
-
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes
-
Moradpour D., Evans M.J., Gosert R., Yuan Z., Blum H.E., Goff S.P., Lindenbach B.D., and Rice C.M. Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes. J. Virol. 78 14 (2004) 7400-7409
-
(2004)
J. Virol.
, vol.78
, Issue.14
, pp. 7400-7409
-
-
Moradpour, D.1
Evans, M.J.2
Gosert, R.3
Yuan, Z.4
Blum, H.E.5
Goff, S.P.6
Lindenbach, B.D.7
Rice, C.M.8
-
28
-
-
55249106707
-
A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication
-
Paredes A.M., and Blight K.J. A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication. J. Virol. 82 21 (2008) 10671-10683
-
(2008)
J. Virol.
, vol.82
, Issue.21
, pp. 10671-10683
-
-
Paredes, A.M.1
Blight, K.J.2
-
29
-
-
0035148546
-
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs
-
Pietschmann T., Lohmann V., Rutter G., Kurpanek K., and Bartenschlager R. Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J. Virol. 75 3 (2001) 1252-1264
-
(2001)
J. Virol.
, vol.75
, Issue.3
, pp. 1252-1264
-
-
Pietschmann, T.1
Lohmann, V.2
Rutter, G.3
Kurpanek, K.4
Bartenschlager, R.5
-
30
-
-
0034763880
-
Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity
-
Qu L., McMullan L.K., and Rice C.M. Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity. J. Virol. 75 22 (2001) 10651-10662
-
(2001)
J. Virol.
, vol.75
, Issue.22
, pp. 10651-10662
-
-
Qu, L.1
McMullan, L.K.2
Rice, C.M.3
-
31
-
-
33644781721
-
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus
-
Rouille Y., Helle F., Delgrange D., Roingeard P., Voisset C., Blanchard E., Belouzard S., McKeating J., Patel A.H., Maertens G., Wakita T., Wychowski C., and Dubuisson J. Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J. Virol. 80 6 (2006) 2832-2841
-
(2006)
J. Virol.
, vol.80
, Issue.6
, pp. 2832-2841
-
-
Rouille, Y.1
Helle, F.2
Delgrange, D.3
Roingeard, P.4
Voisset, C.5
Blanchard, E.6
Belouzard, S.7
McKeating, J.8
Patel, A.H.9
Maertens, G.10
Wakita, T.11
Wychowski, C.12
Dubuisson, J.13
-
32
-
-
34247559591
-
Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery
-
Stone M., Jia S., Heo W.D., Meyer T., and Konan K.V. Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery. J. Virol. 81 9 (2007) 4551-4563
-
(2007)
J. Virol.
, vol.81
, Issue.9
, pp. 4551-4563
-
-
Stone, M.1
Jia, S.2
Heo, W.D.3
Meyer, T.4
Konan, K.V.5
-
33
-
-
39749119301
-
Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication
-
Targett-Adams P., Boulant S., and McLauchlan J. Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication. J. Virol. 82 5 (2008) 2182-2195
-
(2008)
J. Virol.
, vol.82
, Issue.5
, pp. 2182-2195
-
-
Targett-Adams, P.1
Boulant, S.2
McLauchlan, J.3
-
34
-
-
61449111949
-
Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity
-
Thompson A.A., Zou A., Yan J., Duggal R., Hao W., Molina D., Cronin C.N., and Wells P.A. Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity. Biochemistry 48 5 (2009) 906-916
-
(2009)
Biochemistry
, vol.48
, Issue.5
, pp. 906-916
-
-
Thompson, A.A.1
Zou, A.2
Yan, J.3
Duggal, R.4
Hao, W.5
Molina, D.6
Cronin, C.N.7
Wells, P.A.8
-
35
-
-
0036433177
-
Physical interaction between hepatitis C virus NS4B protein and CREB-RP/ATF6beta
-
Tong W.Y., Nagano-Fujii M., Hidajat R., Deng L., Takigawa Y., and Hotta H. Physical interaction between hepatitis C virus NS4B protein and CREB-RP/ATF6beta. Biochem. Biophys. Res. Commun. 299 3 (2002) 366-372
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.299
, Issue.3
, pp. 366-372
-
-
Tong, W.Y.1
Nagano-Fujii, M.2
Hidajat, R.3
Deng, L.4
Takigawa, Y.5
Hotta, H.6
-
36
-
-
17544390782
-
Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo
-
Yanagi M., St Claire M., Shapiro M., Emerson S.U., Purcell R.H., and Bukh J. Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo. Virology 244 1 (1998) 161-172
-
(1998)
Virology
, vol.244
, Issue.1
, pp. 161-172
-
-
Yanagi, M.1
St Claire, M.2
Shapiro, M.3
Emerson, S.U.4
Purcell, R.H.5
Bukh, J.6
-
37
-
-
33744921881
-
Palmitoylation and polymerization of hepatitis C virus NS4B protein
-
Yu G.Y., Lee K.J., Gao L., and Lai M.M. Palmitoylation and polymerization of hepatitis C virus NS4B protein. J. Virol. 80 12 (2006) 6013-6023
-
(2006)
J. Virol.
, vol.80
, Issue.12
, pp. 6013-6023
-
-
Yu, G.Y.1
Lee, K.J.2
Gao, L.3
Lai, M.M.4
-
38
-
-
30744475504
-
Hepatitis C virus non-structural protein NS4B can modulate an unfolded protein response
-
Zheng Y., Gao B., Ye L., Kong L., Jing W., Yang X., Wu Z., and Ye L. Hepatitis C virus non-structural protein NS4B can modulate an unfolded protein response. J. Microbiol. 43 6 (2005) 529-536
-
(2005)
J. Microbiol.
, vol.43
, Issue.6
, pp. 529-536
-
-
Zheng, Y.1
Gao, B.2
Ye, L.3
Kong, L.4
Jing, W.5
Yang, X.6
Wu, Z.7
Ye, L.8
|