메뉴 건너뛰기




Volumn 13, Issue 9, 2009, Pages 929-934

Systemic administration of lidocaine suppresses the excitability of rat cervical dorsal horn neurons and tooth-pulp-evoked jaw-opening reflex

Author keywords

Jaw opening reflex; Lidocaine; Referred pain; Trigeminal system; Upper cervical dorsal horn; Wide dynamic rage neurons

Indexed keywords

LIDOCAINE;

EID: 70349239016     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2008.11.017     Document Type: Article
Times cited : (7)

References (50)
  • 1
    • 0028157262 scopus 로고
    • Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor driven spinal sensitization in the rat
    • Abram S.E., and Yaksh T.L. Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor driven spinal sensitization in the rat. Anesthesiology 80 (1994) 383-391
    • (1994) Anesthesiology , vol.80 , pp. 383-391
    • Abram, S.E.1    Yaksh, T.L.2
  • 2
    • 0025269948 scopus 로고
    • Augmentation of GABA-induced currents in frog sensory neurons by pentobarbital
    • Akaike N., Tokutomi N., and Ikemoto Y. Augmentation of GABA-induced currents in frog sensory neurons by pentobarbital. Am J Physiol 258 (1990) C452-460
    • (1990) Am J Physiol , vol.258
    • Akaike, N.1    Tokutomi, N.2    Ikemoto, Y.3
  • 3
    • 0025095419 scopus 로고
    • The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy
    • Bath F.W., Jensen T.S., Kastrup J., Stigsby B., and Dejgard A. The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy. Pain 40 (1990) 29-34
    • (1990) Pain , vol.40 , pp. 29-34
    • Bath, F.W.1    Jensen, T.S.2    Kastrup, J.3    Stigsby, B.4    Dejgard, A.5
  • 4
    • 0027447508 scopus 로고
    • Central effect of systemic lidocaine mediated by glycine spinal receptors: an iontophoretic study in the rat spinal cord
    • Biella G., and Sotgiu M.L. Central effect of systemic lidocaine mediated by glycine spinal receptors: an iontophoretic study in the rat spinal cord. Brain Res 603 (1993) 201-206
    • (1993) Brain Res , vol.603 , pp. 201-206
    • Biella, G.1    Sotgiu, M.L.2
  • 5
    • 0029092657 scopus 로고
    • Evidence that inhibitory mechanisms mask inappropriate somatotopic connections in the spinal cord of normal rat
    • Biella G., and Sotgiu M.L. Evidence that inhibitory mechanisms mask inappropriate somatotopic connections in the spinal cord of normal rat. J Neurophysiol 74 (1995) 495-505
    • (1995) J Neurophysiol , vol.74 , pp. 495-505
    • Biella, G.1    Sotgiu, M.L.2
  • 7
    • 0030131033 scopus 로고    scopus 로고
    • Effects of cardiac vagal afferent electrostimulation on the responses of trigeminal and trigeminothalamic neurons to noxious orofacial stimulation
    • Bossut D.F., and Maixner W. Effects of cardiac vagal afferent electrostimulation on the responses of trigeminal and trigeminothalamic neurons to noxious orofacial stimulation. Pain 65 (1996) 101-109
    • (1996) Pain , vol.65 , pp. 101-109
    • Bossut, D.F.1    Maixner, W.2
  • 8
    • 0000801907 scopus 로고    scopus 로고
    • NMDA receptor mechanisms contribute to neuoplasticity induced in caudaqlis nociceptive neurons by tooth pulp stimulation
    • Chiang C.Y., Park S.J., Kwan C.L., Hu J.W., and Sessle B.J. NMDA receptor mechanisms contribute to neuoplasticity induced in caudaqlis nociceptive neurons by tooth pulp stimulation. Neurophysiol 80 (1998) 2621-2631
    • (1998) Neurophysiol , vol.80 , pp. 2621-2631
    • Chiang, C.Y.1    Park, S.J.2    Kwan, C.L.3    Hu, J.W.4    Sessle, B.J.5
  • 9
    • 0002891564 scopus 로고
    • Jaw and tongue reflex
    • Dubner R., Sessle B.J., and Storey A.T. (Eds), Plenum, New York
    • Dubner R., Sessle B.J., and Storey A.T. Jaw and tongue reflex. In: Dubner R., Sessle B.J., and Storey A.T. (Eds). The neural basis of oral function (1978), Plenum, New York 246-310
    • (1978) The neural basis of oral function , pp. 246-310
    • Dubner, R.1    Sessle, B.J.2    Storey, A.T.3
  • 10
    • 34047266824 scopus 로고    scopus 로고
    • Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory transmission in spinal substantia gelatinosa neurons of mouse
    • Ferrini F., Salio C., Vergnano A.M., and Merighi A. Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory transmission in spinal substantia gelatinosa neurons of mouse. Pain 129 (2007) 195-209
    • (2007) Pain , vol.129 , pp. 195-209
    • Ferrini, F.1    Salio, C.2    Vergnano, A.M.3    Merighi, A.4
  • 11
    • 0034003823 scopus 로고    scopus 로고
    • Integration of viscerosomatic sensory inputs at the spinal level
    • Foreman R.D. Integration of viscerosomatic sensory inputs at the spinal level. Prog Brain Res 122 (2000) 209-221
    • (2000) Prog Brain Res , vol.122 , pp. 209-221
    • Foreman, R.D.1
  • 12
    • 33749066345 scopus 로고    scopus 로고
    • Effect of NMDA and non-NMDA receptor antagonists on the superior sagital sinus-evoked C1 spinal neurons responding to tooth-pulp stimulation in rats
    • Fujimi Y., Takeda M., Tanimoto T., and Matsumoto S. Effect of NMDA and non-NMDA receptor antagonists on the superior sagital sinus-evoked C1 spinal neurons responding to tooth-pulp stimulation in rats. Odontology 94 (2006) 22-28
    • (2006) Odontology , vol.94 , pp. 22-28
    • Fujimi, Y.1    Takeda, M.2    Tanimoto, T.3    Matsumoto, S.4
  • 13
    • 0031961991 scopus 로고    scopus 로고
    • Systemic lidocaine induces expansion of the receptive field of spinal dorsal horn neurons in rats
    • Hao J.-.X., Kupers R., and Wiesenfeld-Hallin Z. Systemic lidocaine induces expansion of the receptive field of spinal dorsal horn neurons in rats. Exp Brain Res 118 (1998) 431-434
    • (1998) Exp Brain Res , vol.118 , pp. 431-434
    • Hao, J.-.X.1    Kupers, R.2    Wiesenfeld-Hallin, Z.3
  • 14
    • 0021895384 scopus 로고
    • Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurons
    • Harper A.A., and Lawson S.N. Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurons. J Physiol (Lond) 359 (1985) 31-46
    • (1985) J Physiol (Lond) , vol.359 , pp. 31-46
    • Harper, A.A.1    Lawson, S.N.2
  • 15
    • 37849037118 scopus 로고    scopus 로고
    • The role of TRPV1 receptors in the antinociceptive effect of anadamide at spinal level
    • Horvath G., Kekesi G., Nagy E., and Benedek G. The role of TRPV1 receptors in the antinociceptive effect of anadamide at spinal level. Pain 134 (2008) 277-284
    • (2008) Pain , vol.134 , pp. 277-284
    • Horvath, G.1    Kekesi, G.2    Nagy, E.3    Benedek, G.4
  • 16
    • 0023241524 scopus 로고
    • Intravenous lidocaine infusion-a new treatment of chronic painful diabetic neuropathy
    • Kastrup J., Petersen P., Dejard A., Angelo H.R., and Hilsted J. Intravenous lidocaine infusion-a new treatment of chronic painful diabetic neuropathy. Pain 28 (1987) 69-75
    • (1987) Pain , vol.28 , pp. 69-75
    • Kastrup, J.1    Petersen, P.2    Dejard, A.3    Angelo, H.R.4    Hilsted, J.5
  • 17
    • 33646046469 scopus 로고    scopus 로고
    • Effects of systemic administration of lidocaine and QX-314 on hyperexcitability of spinal dorsal horn neurons after incision in the rat
    • Kawamata M., Sugino S., Narimatsu E., Yamauchi M., Kiya T., Furuse S., and Namiki A. Effects of systemic administration of lidocaine and QX-314 on hyperexcitability of spinal dorsal horn neurons after incision in the rat. Pain 122 (2006) 68-80
    • (2006) Pain , vol.122 , pp. 68-80
    • Kawamata, M.1    Sugino, S.2    Narimatsu, E.3    Yamauchi, M.4    Kiya, T.5    Furuse, S.6    Namiki, A.7
  • 18
    • 34247330606 scopus 로고    scopus 로고
    • Activation of TRPA1 channel faclilitates excitatory synaptic transmission in the substantia gelatinosa neurons of the adult spinal cord
    • Kosugi M., Nakatukasa T., Fujita T., Kuroda Y., and Kumamoto E. Activation of TRPA1 channel faclilitates excitatory synaptic transmission in the substantia gelatinosa neurons of the adult spinal cord. J Neurosci 27 (2007) 4443-4451
    • (2007) J Neurosci , vol.27 , pp. 4443-4451
    • Kosugi, M.1    Nakatukasa, T.2    Fujita, T.3    Kuroda, Y.4    Kumamoto, E.5
  • 19
    • 28844471303 scopus 로고    scopus 로고
    • Distinct expression of TRPM8, TRPA1 and TRPV1mRNAs in rat primary afferent neurons with Aδ/C-fiber and colocalization with Trk receptors
    • Kobayashi K., FukudaT Obata.K., Yamanaka H., Dai Y., Tokunaga A., and Noguchi K. Distinct expression of TRPM8, TRPA1 and TRPV1mRNAs in rat primary afferent neurons with Aδ/C-fiber and colocalization with Trk receptors. J Comp Neurol 493 (2005) 596-606
    • (2005) J Comp Neurol , vol.493 , pp. 596-606
    • Kobayashi, K.1    FukudaT, Obata.K.2    Yamanaka, H.3    Dai, Y.4    Tokunaga, A.5    Noguchi, K.6
  • 20
    • 38849094740 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons
    • Leffler A., Fischer M.J., Rehner D., Kienei S., Kistner K., Sauer S., et al. The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons. J Clin Invest 118 (2008) 763-776
    • (2008) J Clin Invest , vol.118 , pp. 763-776
    • Leffler, A.1    Fischer, M.J.2    Rehner, D.3    Kienei, S.4    Kistner, K.5    Sauer, S.6
  • 21
    • 0028169159 scopus 로고
    • A antagonists reduce the inhibition of primate spinothalamic tract neurons produced by stimulation in periaqueductal gray
    • A antagonists reduce the inhibition of primate spinothalamic tract neurons produced by stimulation in periaqueductal gray. Brain Res 654 (1994) 286-302
    • (1994) Brain Res , vol.654 , pp. 286-302
    • Lin, Q.1    Peng, Y.2    Willis, W.D.3
  • 22
    • 0014901855 scopus 로고
    • Jaw depression elicited by tooth pulp stimulation
    • Mahan P., and Anderson K.V. Jaw depression elicited by tooth pulp stimulation. Exp Neurol 29 (1970) 439-448
    • (1970) Exp Neurol , vol.29 , pp. 439-448
    • Mahan, P.1    Anderson, K.V.2
  • 23
    • 0034237501 scopus 로고    scopus 로고
    • Systemic lidocaine for neuropathic pain relief
    • Mao J., and Chen L.L. Systemic lidocaine for neuropathic pain relief. Pain 87 (2000) 7-17
    • (2000) Pain , vol.87 , pp. 7-17
    • Mao, J.1    Chen, L.L.2
  • 24
    • 0022384521 scopus 로고
    • Is the jaw opening reflex a valid model of pain?
    • Mason P., Strassman A., and Maciewicz R. Is the jaw opening reflex a valid model of pain?. Brain Res Rev 10 (1985) 137-146
    • (1985) Brain Res Rev , vol.10 , pp. 137-146
    • Mason, P.1    Strassman, A.2    Maciewicz, R.3
  • 25
    • 0033045457 scopus 로고    scopus 로고
    • Effects of electrical stimulation of the tooth pulp and phrenic nerve fibers on the C1 spinal neurons in the rats
    • Matsumoto S., Takeda M., and Tanimoto T. Effects of electrical stimulation of the tooth pulp and phrenic nerve fibers on the C1 spinal neurons in the rats. Exp Brain Res 126 (1999) 351-358
    • (1999) Exp Brain Res , vol.126 , pp. 351-358
    • Matsumoto, S.1    Takeda, M.2    Tanimoto, T.3
  • 26
    • 0016802885 scopus 로고
    • Localization of masticatory motor neurons in the cat and rat by means of retrograde axonal transport of horse radish peroxydase
    • Mizuno N., Konishi A., and Sato M. Localization of masticatory motor neurons in the cat and rat by means of retrograde axonal transport of horse radish peroxydase. J Comp Neurol 164 (1975) 105-116
    • (1975) J Comp Neurol , vol.164 , pp. 105-116
    • Mizuno, N.1    Konishi, A.2    Sato, M.3
  • 27
    • 0034093843 scopus 로고    scopus 로고
    • Intravenous lidocaine inhibits visceral nociceptive reflex and spinal neurons in the rat
    • Ness T.J. Intravenous lidocaine inhibits visceral nociceptive reflex and spinal neurons in the rat. Anesthesiology 92 (2000) 1685-1691
    • (2000) Anesthesiology , vol.92 , pp. 1685-1691
    • Ness, T.J.1
  • 28
    • 33646392240 scopus 로고    scopus 로고
    • Which spinal cutaneous nociceptive neurons are inhibited by intravenous lidocaine in the rat ?
    • Ness T.J., and Randich A. Which spinal cutaneous nociceptive neurons are inhibited by intravenous lidocaine in the rat ?. Reg Anes Pain Med 31 (2006) 248-253
    • (2006) Reg Anes Pain Med , vol.31 , pp. 248-253
    • Ness, T.J.1    Randich, A.2
  • 29
    • 3042745441 scopus 로고    scopus 로고
    • Convergence of nociceptive information from temporomandibular joint and tooth pulp afferents on C1 spinal neurons in the rats
    • Nishikawa T., Takeda M., Tanimoto T., and Matsumoto S. Convergence of nociceptive information from temporomandibular joint and tooth pulp afferents on C1 spinal neurons in the rats. Life Sci 75 (2004) 1465-1478
    • (2004) Life Sci , vol.75 , pp. 1465-1478
    • Nishikawa, T.1    Takeda, M.2    Tanimoto, T.3    Matsumoto, S.4
  • 30
    • 0029923562 scopus 로고    scopus 로고
    • Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppress phase-2 activity
    • Puig S., and Sorkin L.S. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppress phase-2 activity. Pain 64 (1996) 345-355
    • (1996) Pain , vol.64 , pp. 345-355
    • Puig, S.1    Sorkin, L.S.2
  • 31
    • 0035214924 scopus 로고    scopus 로고
    • Strychnine alters responses properties of trigeminal nociceptive neurons in the rat
    • Ressot C., Collado V., Molat J.-L., and Dallel R. Strychnine alters responses properties of trigeminal nociceptive neurons in the rat. J Neurophysiol 86 (2001) 3069-3072
    • (2001) J Neurophysiol , vol.86 , pp. 3069-3072
    • Ressot, C.1    Collado, V.2    Molat, J.-L.3    Dallel, R.4
  • 32
    • 0029955764 scopus 로고    scopus 로고
    • A receptors by barbiturates in cultured rat hippocampal neurons
    • A receptors by barbiturates in cultured rat hippocampal neurons. J Physiol 497 (1996) 509-522
    • (1996) J Physiol , vol.497 , pp. 509-522
    • Rho, J.M.1    Donevan, S.D.2    Rogawski, M.A.3
  • 33
    • 0026095534 scopus 로고
    • Both intravenous lidocaine and morphine reduce the pain of post therapeutic neuralgia
    • Rowbotham M.C., Reisner-Keller L.A., and Fields H.L. Both intravenous lidocaine and morphine reduce the pain of post therapeutic neuralgia. Neurology 41 (1991) 1024-1028
    • (1991) Neurology , vol.41 , pp. 1024-1028
    • Rowbotham, M.C.1    Reisner-Keller, L.A.2    Fields, H.L.3
  • 34
    • 0030470074 scopus 로고    scopus 로고
    • Neuonal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a μ-opiate receptor agonist
    • Sorkin L.S., and Puig S. Neuonal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a μ-opiate receptor agonist. Pain 68 (1996) 283-292
    • (1996) Pain , vol.68 , pp. 283-292
    • Sorkin, L.S.1    Puig, S.2
  • 35
    • 0025823366 scopus 로고
    • Selective inhibition by systemic lidocaine of noxious evoked activity in rat dorsal horn neurons
    • Sotgiu M.L., Lacerenza M., and Marchetti P. Selective inhibition by systemic lidocaine of noxious evoked activity in rat dorsal horn neurons. Neuroreport 2 (1991) 425-428
    • (1991) Neuroreport , vol.2 , pp. 425-428
    • Sotgiu, M.L.1    Lacerenza, M.2    Marchetti, P.3
  • 36
    • 0026715144 scopus 로고
    • Effect of systemic lidocaine on dorsal horn neurons hyperactivity following chronic peripheral nerve injury in rats
    • Sotgiu M.L., Lacerenza M., and Marchetti P. Effect of systemic lidocaine on dorsal horn neurons hyperactivity following chronic peripheral nerve injury in rats. Somatsenses Mot Res 9 (1992) 227-233
    • (1992) Somatsenses Mot Res , vol.9 , pp. 227-233
    • Sotgiu, M.L.1    Lacerenza, M.2    Marchetti, P.3
  • 37
    • 0028329251 scopus 로고
    • Different time -courses of i.v. lidocaine effect on ganglionic and spinal units in neuropathc rats
    • Sotgiu M.L., Biella G., Castagna A., Lacerenza M., and Marchetti P. Different time -courses of i.v. lidocaine effect on ganglionic and spinal units in neuropathc rats. Neuroreport 5 (1994) 873-876
    • (1994) Neuroreport , vol.5 , pp. 873-876
    • Sotgiu, M.L.1    Biella, G.2    Castagna, A.3    Lacerenza, M.4    Marchetti, P.5
  • 38
    • 0027415775 scopus 로고
    • Tooth pulp primary neurons: Cell size analysis, central connection and carbonic anhydrase activity
    • Sugimoto T., and Takemura M. Tooth pulp primary neurons: Cell size analysis, central connection and carbonic anhydrase activity. Brain Res Bull 30 (1993) 221-226
    • (1993) Brain Res Bull , vol.30 , pp. 221-226
    • Sugimoto, T.1    Takemura, M.2
  • 39
    • 0037352328 scopus 로고    scopus 로고
    • Local anaesthetics have different mechanisms and sites of action at the recombinant N-methyl-d-aspartate (NMDA) receptors
    • Sugimoto M., Uchida I., and Mashimo T. Local anaesthetics have different mechanisms and sites of action at the recombinant N-methyl-d-aspartate (NMDA) receptors. Br J Pharmacol 138 (2003) 862-876
    • (2003) Br J Pharmacol , vol.138 , pp. 862-876
    • Sugimoto, M.1    Uchida, I.2    Mashimo, T.3
  • 40
    • 0032168705 scopus 로고    scopus 로고
    • Supppressive effect of vagal afferents on the activity of trigeminal spinal neurons related to the jaw-opening reflex in rats: involvement of the endogenous opioid system
    • Takeda M., Tanimoto T., and Matsumoto S. Supppressive effect of vagal afferents on the activity of trigeminal spinal neurons related to the jaw-opening reflex in rats: involvement of the endogenous opioid system. Brain Res Bull 47 (1998) 49-56
    • (1998) Brain Res Bull , vol.47 , pp. 49-56
    • Takeda, M.1    Tanimoto, T.2    Matsumoto, S.3
  • 41
    • 0032843296 scopus 로고    scopus 로고
    • Effects of N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists on the tooth pulp-evoked C1 neurons in the rat
    • Takeda M., Tanimoto T., and Matsumoto S. Effects of N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists on the tooth pulp-evoked C1 neurons in the rat. Exp Brain Res 128 (1999) 303-308
    • (1999) Exp Brain Res , vol.128 , pp. 303-308
    • Takeda, M.1    Tanimoto, T.2    Matsumoto, S.3
  • 42
    • 0033769977 scopus 로고    scopus 로고
    • A receptor activation in the trigeminal spinal nucleus caudalis neurons in rats
    • A receptor activation in the trigeminal spinal nucleus caudalis neurons in rats. Exp Brain Res 134 (2000) 409-416
    • (2000) Exp Brain Res , vol.134 , pp. 409-416
    • Takeda, M.1    Tanimoto, T.2    Matsumoto, S.3
  • 43
    • 11244283288 scopus 로고    scopus 로고
    • Role of capsaicin sensitive primary afferent fiber input from masseter muscle into C1 spinal neuron responding to tooth-pulp stimulation in rats
    • Takeda M., Tanimoto T., Ito M., Nasu M., and Matsumoto S. Role of capsaicin sensitive primary afferent fiber input from masseter muscle into C1 spinal neuron responding to tooth-pulp stimulation in rats. Exp Brain Res 160 (2005) 107-117
    • (2005) Exp Brain Res , vol.160 , pp. 107-117
    • Takeda, M.1    Tanimoto, T.2    Ito, M.3    Nasu, M.4    Matsumoto, S.5
  • 44
    • 33748871152 scopus 로고    scopus 로고
    • 2 adrenoreceptors suppresses the excitability of C1 spinal neurons having convergent inputs from tooth-pulp and superior sagital sinus in rats
    • 2 adrenoreceptors suppresses the excitability of C1 spinal neurons having convergent inputs from tooth-pulp and superior sagital sinus in rats. Exp Brain Res 74 (2006) 210-220
    • (2006) Exp Brain Res , vol.74 , pp. 210-220
    • Takeda, M.1    Tanimoto, T.2    Takahashi, M.3    Kadoi, J.4    Kadoi, J.5    Matsumoto, S.6
  • 45
    • 0036041651 scopus 로고    scopus 로고
    • Suppressive effect of vagal afferents on cervical dorsal horn neurons responding to tooth-pulp electrical stimulation in the rats
    • Tanimoto T., Takeda M., and Matsumoto S. Suppressive effect of vagal afferents on cervical dorsal horn neurons responding to tooth-pulp electrical stimulation in the rats. Exp Brain Res 145 (2002) 468-479
    • (2002) Exp Brain Res , vol.145 , pp. 468-479
    • Tanimoto, T.1    Takeda, M.2    Matsumoto, S.3
  • 46
    • 0025368953 scopus 로고
    • Light microscope study of the co-existence of GABA-like immunoreactivity in the spinal cord of the rat
    • Todd A.J., and Sullivan A.C. Light microscope study of the co-existence of GABA-like immunoreactivity in the spinal cord of the rat. J Comp Neurol 296 (1990) 496-505
    • (1990) J Comp Neurol , vol.296 , pp. 496-505
    • Todd, A.J.1    Sullivan, A.C.2
  • 48
    • 0022351051 scopus 로고
    • The systemic administration of local anesthetics produces a selective depression of C-afferent fiber evoked activity in the spinal cord
    • Woolf C.J., and Wiesenfeld-Hallin Z. The systemic administration of local anesthetics produces a selective depression of C-afferent fiber evoked activity in the spinal cord. Pain 23 (1985) 361-374
    • (1985) Pain , vol.23 , pp. 361-374
    • Woolf, C.J.1    Wiesenfeld-Hallin, Z.2
  • 49
    • 0019796609 scopus 로고
    • Glycine receptor. Light microscopic autoradiographic localization with [3H] strychnine
    • Zarbin M.A., Wamsley J.K., and Kuhar M.J. Glycine receptor. Light microscopic autoradiographic localization with [3H] strychnine. J Neurosci 1 (1981) 532-547
    • (1981) J Neurosci , vol.1 , pp. 532-547
    • Zarbin, M.A.1    Wamsley, J.K.2    Kuhar, M.J.3
  • 50
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.