Neuronal model of tactile allodynia produced by spinal strychnine: Effects of excitatory amino acid receptor antagonists and a μ-opiate receptor agonist

Pain

Volumn 68, Issue 2-3, 1996, Pages 283-292

  Sorkin, Linda S ^a   Puig, Sylvie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cat; glycine; neuropathic pain; pain; spinal cord

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR STIMULATING AGENT; GLYCINE; MU OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE AGONIST; STRYCHNINE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAT; CONTROLLED STUDY; DRUG EFFECT; INTRASPINAL DRUG ADMINISTRATION; NEUROPATHY; NONHUMAN; PAIN; PRIORITY JOURNAL; SPINAL CORD;

2-AMINO-5-PHOSPHONOVALERATE; ALFENTANIL; ANALGESICS, OPIOID; ANIMALS; CATS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLYCINE AGENTS; INJECTIONS, SPINAL; MALE; MODELS, NEUROLOGICAL; NERVE FIBERS; NEURONS; PRESSURE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, OPIOID, MU; SENSORY THRESHOLDS; STRYCHNINE;

EID: 0030470074     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(96)03130-2     Document Type: Article

References (48)

1. Arnér, S. and Meyerson, B.A., Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain, Pain, 33 (1988) 11-23.
2. Basbaum, A.I., Distribution of glycine receptor immunoreactivity in the spinal cord of the rat: cytochemical evidence for a differential glycinergic control of lamina I and V nociceptive neurons, J. Comp. Neurol., 278 (1988) 330-336.
3. Beyer, C., Roberts, L. and Komisaruk, B.R., Hyperalgesia induced by altered glycinergic activity at the spinal cord, Life Sci., 37 (1985) 875-882.
4. Chung, J.M., Surmeier, D.J., Lee, K.H., Sorkin, L.S., Honda, C.N., Tsong, Y. and Willis, W.D., Classification of primate spinothalamic and somatosensory thalamic neurons based on cluster analysis, J. Neurophysiol., 56 (1986) 308-327.
5. Collins, J.G., Ren, K., Saito, Y., Iwasaki, H. and Tang, J., Plasticity of some spinal dorsal horn neurons as revealed by pentobarbital-induced disinhibition, Brain Res., 525 (1990) 189-197.
6. Curtis, D.R., Duggan, A.W. and Johnston, G.A.R., The specificity of strychnine as a glycine receptor antagonist, Exp. Brain Res., 12 (1971) 547-565.
7. Curtis, D.R., Hösli, L. and Johnston, G.A.R., Inhibition of spinal neurones by glycine, Nature, 215 (1967) 1502-1503.
8. Davidoff, R.A., Graham, L.T., Shank, R.P., Werman, R. and Aprison, M.H., Changes in amino acid concentration associated with loss of spinal interneurons, J. Neurochem., 14 (1967) 1025-1031.
9. Dougherty, P.M., Palecek, J., Paleckova, V., Sorkin, L.S. and Willis, W.D., The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal and electrical stimuli, J. Neurosci., 12 (1992) 3025-3041.
10. Eccles, J.C., The Physiology of Synapses, Springer Verlag, Berlin, 1959.
11. A receptor gamma subunit mRNA in the rat dorsal root ganglion cells, Mol. Brain Res., 12 (1992) 335-338.
12. Game, C.J.A. and Lodge, D., The pharmacology of the inhibition of dorsal horn neurones by impulses in myelinated cutaneous afferents in the cat, Exp. Brain Res., 23 (1975) 75-84.
13. Gamse, R., Holzer, P. and Lembeck, F., Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurons, Arch. Pharmacol., 308 (1979) 281-285.
14. Hao, J.-X., Xu, X.-J., Aldskogius, H., Seiger, Å. and Wiesenfeld-Hallin, Z., Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation, Pain, 45 (1991a) 175-185.
15. Hao, J.-X., Xu, X.-J., Aldskogius, H., Seiger, A. and Wiesenfeld-Hallin, Z., The excitatory amino acid receptor antagonist MK-801 prevents the hypersensitivity induced by spinal cord ischemia in the rat, Exp. Neurol., 113 (1991b) 182-191.
16. Hao, J.-X., Xu, X.-J., Yu, Y.-X., Seiger, Å. and Wiesenfeld-Hallin, Z., Transient spinal cord ischemia induces temporary hypersensitivity of dorsal horn wide dynamic range neurons to myelinated, but not unmyelinated, fiber input, J. Neurophysiol., 68 (1992a) 384-391.
17. Hao, J.-X., Watson, B.D., Xu, X.-J., Wiesenfeld-Hallin, Z., Seiger, A. and Sundstrom, E., Protective effect of the NMDA antagonist MK-801 on photochemically induced spinal lesions in the rat, Exp. Neurol., 118 (1992b) 143-152.
18. Kenshalo, Jr., D.R., Anton, F. and Dubner, R., The detection and perceived intensity of noxious thermal stimuli in monkey and man, J. Neurophysiol., 62 (1989) 429-436.
19. Khayyat, G.F., Yu, Y.J. and King, R.B., Response patterns to noxious and non-noxious stimuli in rostral trigeminal relay nuclei, Brain Res., 97 (1957) 47-60.
20. King, R.B. and Barnett, J.C., Studies of the trigeminal nerve potentials: overreaction to tactile facial stimulation in acute laboratory preparations, J. Neurosurg., 14 (1957) 617-627.
21. Minami, T., Uda, R., Horiguchi, S., Ito, S., Hyodo, M. and Hayaishi, O., Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice, Pain, 57 (1994) 217-223.
22. Owens, C.M., Zhang, D. and Willis, W.D., Changes in the response states of primate spinothalamic tract cells caused by mechanical damage of the skin or activation of descending controls, J. Neurophysiol., 67 (1992) 1509-1527.
23. Pohl, M., Lombard, M.C., Bourgoin, S., Carayon, A., Benoliel, J.J., Mauborge, A., Besson, J.M., Hamon, M, and Cesselin, F., Opioid control of the in vitro release of calcitonin gene-related peptide from primary afferent fibres projecting in the rat cervical cord, Neuropeptides, 14 (1989) 151-159.
24. Powell, J.J. and Todd, A.J., Light and electron microscope study of GABA-immunoreactive neurones in lamina III of rat spinal cord, J. Comp. Neurol., 315 (1992) 125-136.
25. Price, D.D. and Dubner, R., Neurons that subserve the sensory discriminative aspect of pain, Pain, 3 (1977) 307-338.
26. Seltzer, Z., Cihn, S., Ginzburg, R. and Beilin, B., Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge, Pain, 45 (1991) 69-75.
27. Sherman, S. and Loomis, C.W., Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat, Pain, 56 (1994) 17-29.
28. A and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord, J. Neurophysiol., 72 (1994) 169-179.
29. Simone, D.A., Sorkin, L.S., Oh, U.T., Chung, J.M., Owens, C., LaMotte, R.M. and Willis, W.D., Neurogenic hyperalgesia: central correlates in responses of spinothalamic tract neurons, J. Neurophysiol., 66 (1991) 228-246.
30. Sorkin, L.S., McAdoo, D.J. and Willis, W.D., Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn, Brain Res., 618 (1993) 95-108.
31. Sorkin, L.S., Morrow, T.J. and Casey, K.L., Physiological identification of afferent fibers and postsynaptic sensory neurons in the spinal cord of the intact, awake cat, Exp. Neurol., 99 (1988) 412-417.
32. Sorkin, L.S. and Puig, S., Spinal strychnine increases responses of nociceptive neurons to low threshold input and lengthens afterdischarge, Neurosci. Abstr., 20 (1994) 1391.
33. Sorkin, L.S., Steinman, J.L., Hughes, M.G., Willis, W.D. and McAdoo, D.J., Microdialysis recovery of serotonin released in spinal cord dorsal horn, J. Neurosci. Methods, 23 (1988) 131-138.
34. Sugimoto, T., Bennet, G.J. and Kajander, K.C., Transsynaptic degeneration in the superficial dorsal horn after sciatic nerve injury, transection and strychnine, Pain, 42 (1990) 385-393.
35. Sugimoto, T., Takemura, M., Okubo, J. and Sakai, A., Strychnine and L-allyl glycine but not bicuculine and picrotoxin induce transsynaptic degeneration following transection of the inferior alveolar nerve in adult rats, Brain Res., 341 (1985) 393-398.
36. Sugimoto, T., Takemura, M., Sakai, A. and Ishimaru, M., Rapid transneuronal destruction following peripheral nerve transection in the medullary dorsal horn is enhanced by strychnine, picrotoxin and bicuculline, Pain, 30 (1987) 383-393.
37. Todd, A.J., An electron microscope study of glycine-like immunoreactivity in laminae I-III of the spinal dorsal horn of the rat, Neuroscience, 39 (1990) 387-394.
38. Todd, A.J., Immunohistochemical evidence that acetylcholine and glycine exist in different populations of GABAergic neurons in lamina III of rat spinal dorsal horn, Neuroscience, 44 (1991) 741-746.
39. Todd, A.J., Maxwell, D.J. and Brown, A.G., Relationships between hair-follicle afferent axons and glycine immunoreactive profiles in cat spinal dorsal horn, Brain Res., 564 (1991) 132-137.
40. Todd, A.J. and Sullivan, A.C., Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivity in the spinal cord of the rat, J. Comp. Neurol., 296 (1990) 496-505.
41. Willcockson, W.S., Chung, J.M., Hori, Y., Lee, K.H. and Willis, W.D., Effects of iontophoretically released amino acids and amines on primate spinothalamic tract cells, J. Neurosci., 4 (1984) 732-740.
42. Woolf, C.J., Shortland, P. and Silviotti, L.G., Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent action, Pain, 58 (1994) 141-155.
43. Yaksh, T.L., Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists, Pain, 37 (1989) 111-123.
44. Yaksh, T.L., The spinal actions of opioids. In: A. Heiz (Ed.), Handbook of Experimental Pharmacology, Vol. 104/II, Berlin, Springer-Verlag, 1993, pp. 53-90.
45. Yamamoto, T. and Yaksh, T.L., Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801, Pain, 54 (1993) 79-84.
46. Yokota, T., Nishikawa, N. and Nishikawa, Y., Effects of strychnine upon different classes of trigeminal subnucleus caudalis neurons, Brain Res., 168 (1979) 430-434.
47. Zhang, D.X., Owens, C.M. and Willis, W.D., Two forms of inhibition of spinothalamic tract neurons produced by stimulation of the periaqueductal gray and the cerebral cortex, J. Neurophysiol., 65 (1991) 1567-1579.
48. Zieglgänsberger, W. and Herz, A., Changes in cutaneous receptive fields of spino-cervical tract neurones and other dorsal horn neurones by microelectrophoretically administered amino acids, Exp. Brain Res., 13 (1971) 111-126.