Intravenous lidocaine inhibits visceral nociceptive reflexes and spinal neurons in the rat

Anesthesiology

Volumn 92, Issue 6, 2000, Pages 1685-1691

  Ness, Timothy J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Dorsal horn; Pseudaffective; Sodium channel blocker visceromotor

Indexed keywords

LIDOCAINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR REFLEX; CERVICAL SPINAL CORD INJURY; COLON DILATATION; CONTROLLED STUDY; DECEREBRATION; DOSE RESPONSE; LAMINECTOMY; LUMBOSACRAL SPINE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SPINAL CORD TRANSSECTION;

EID: 0034093843     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200006000-00028     Document Type: Article

References (40)

1. Glazer S, Portenoy RK: Systemic local anesthetics in pain control. J Pain Symptom Manage 1991; 6:30-9
2. Sörensen J, Bengtsson A, Bäckman E, Henriksson KG, Bengtsson M: Pain analysis in patients with fibromyalgia: Effects of intravenous morphine, lidocaine and ketamine. Scand J Rheumatol 1995; 24:360-5
3. Kingery WS: A critical review of controlled clinical trials for peripheral neuropathic pain and complex regional pain syndromes. Pain 1997; 73:123-39
4. Edmondson EA, Simpson Jr RK, Stubler DK, Beric A: Systemic lidocaine therapy for poststroke pain. South Med J 1993; 86:1093-6
5. 2, antibody therapy in children with neuroblastoma: A report of a series. Anesth Analg 1997; 85:794-6
6. Sindrup SH: Treatment of the symptoms of diabetic neuropathy. Pain Dig 1993; 3:7-14
7. Woolf CJ. Wiesenfeld-Hallin Z: The systemic administration of local anaesthetics produces a selective depression of C-afferent fibre evoked activity in the spinal cord. Pain 1985; 23:361-74
8. de Jong RH, Robles R, Corbin RW: Central actions of lidocaine: Synaptic transmission. ANESTHESIOLOGY 1969;30:19-23
9. de Jong RH, Nace RA: Nerve impulse conduction during intravenous lidocaine injection. ANESTHESIOLOGY 1968; 29:22-8
10. Dohi S Kitihata LM, Toyooka H, Ohtani M, Namiki A, Taub A: An analgesic action of intravenously administered lidocaine on dorsal-horn neurons responding to noxious thermal stimulation. ANESTHESIOLOGY 1979; 51:123-6
11. Wallace MS, Laitin S, Licht D, Yaksh TL: Concentration-effect relations for intravenous lidocaine infusions in human volunteers: Effects on acute sensory thresholds and capsaicin-evoked hyperpathia. ANESTHESIOLOGY 1997; 86:1262-72
12. Koppert W, Zeck S, Sittl R, Likar R, Knoll R, Schmelz M: Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans. ANESTHESIOLOGY 1998; 89:1345-53
13. Mayer EA, Gebhart GF: Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994; 107:271-93
14. Ness TJ, Metcalf AM, Gebhart GF: A psychophysiological study in humans using phasic colonie distension as a noxious visceral stimulus. Pain 1990; 43:377-86
15. Ness TJ: Models of visceral nociception. Inst Lab Animal Res J 1999; 40:119-28
16. Ness TJ, Gebhart GF: Colorectal distension as a noxious visceral stimulus: Physiologic and pharmacologic characterization of pseudaffective reflexes in the rat. Brain Res 1988; 450:153-69
17. Ness TJ, Gebhart GF: Characterization of neuronal responses to noxious visceral and somatocutaneous stimuli in the medial lumbosacral spinal cord of the rat. J Neurophysiol 1987; 57:1867-92
18. Ness TJ, Gebhart GF: Interactions between visceral and cutaneous nociception in the rat. I. Noxious cutaneous stimuli inhibit visceral nociceptive neurons and reflexes. J Neurophysiol 1991; 66:20-8
19. Omote K, Kawamata M, Iwasaki H, Namiki A: Effects of morphine on neuronal and behavioural responses to visceral and somatic nociception at the level of the spinal cord. Acta Anesthesiol Scand 1994; 38:514-7
20. Ness TJ, Gebhart GF: Differential effects of morphine and clonidine upon visceral and cutaneous nociceptive transmission in the rat. J Neurophysiol 1989; 62:220-30
21. Ness TJ: Kappa opioid receptor agonists differentially inhibit two classes of rat spinal neurons excited by colorectal distention. Gastroenterology 1999; 117:388-94
22. Galer BS, Harle J, Rowbotham MC: Response to intravenous lidocaine infusion predicts subsequent response to oral mexiletine: A prospective study. J Pain Symptom Manage 1996; 12:161-7
23. Ferrante FM, Paggioli J, Cherukuri S, Arthur GR: The analgesic response to intravenous lidocaine in the treatment of neuropathic pain. Anesth Analg 1996; 82:91-7
24. Jonsson A, Cassuto J, Hanson B: Inhibition of burn pain by intravenous lignocaine infusion. Lancet 1991; 338:151-2
25. Ackerman WE, Phero JC, McDonald JS: Analgesia with intravenous local anesthetics, Practical Management of Pain, 2nd Edition. Edited by Raj PP. St. Louis, Mosby Year Book, 1992, pp 851-5
26. Groudine SB, Fisher HAG, Kaufman RP Jr, Patel MK, Wilkins LJ, Mehta SA, Lumb PD: Intravenous lidocaine speeds the return of bowel function decreases postoperative pain, and shortens hospital stay in patients undergoing radical retropubic prostatectomy. Anesth Analg 1998; 86:235-9
27. Bonica JJ: Technique of nerve blocking: The intravenous administration of local anesthetic agents in the management of pain, The Management of Pain, 2nd Edition. Philadelphia, Lea & Febigan, 1953, pp 552-64
28. Parris WCV, Gerlock AJ, MacDonnell RC: Intra-arterial chloroprocaine for the control of pain associated with partial splenic embolization. Anesth Analg 1981; 60:112-5
29. Sotgui ML, Lacerenza M Marchettini P: Selective inhibition by systemic lidocaine of noxious evoked activity in rat dorsal horn neurons. NeuroReport 1991; 2:425-8
30. Nagy I, Woolf CJ: Lignocaine selectively reduced C fibre-evoked neuronal activity in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations: Implications for the development of novel, central acting analgesics. Pain 1996; 64:59-70
31. Biella G, Sotgiu ML: Central effects of systemic lidocaine mediated by glycine spinal receptors: An iontophoretic study in the rat spinal cord. Brain Res 1993; 603:201-6
32. Sotgui ML, Biella G, Castagna A, Lacerenza M, Marchettini P: Different time-courses of i.v. lidocaine effect on ganglionic and spinal units in neuropathic rats. NeuroReport 1994; 5:873-6
33. Puig S, Sorkin LS: Formalin-evoked activity in identified primary afferent fibers: Systemic lidocaine suppresses phase-2 activity. Pain 1995; 64:345-55
34. Tanelian DL, MacIver MB: Analgesic concentrations of lidocaine suppress tonic A-delta and C fiber discharges produced by acute injury. ANESTHESIOLOGY 1991; 74:934-6
35. Haegerstam G: Effect of i.v. administration of lignocaine and tetrodotoxin on sensory units in the tooth of the cat. Br J Anaesth 1979; 51:487-91
36. Devor M, Wall PD, Catalan N: Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction. Pain 1992; 48:261-8
37. Lembo T, Munakata J, Mertz H, Niazi N, Kodner A, Nikas V, Mayer EA: Evidence for the hypersensitivity of lumbar splanchnic afferents in irritable bowel syndrome. Gastroenterology 1994; 107: 1686-96
38. Abdi S, Lee DH, Chung JM: The anti-allodynic effects of amitriptyline, gabapentin and lidocaine in a rat model of neuropathic pain. Anesth Analg 1998; 87:1360-6
39. Chaplan SR, Bach FW, Shafer SL, Yaksh TL: Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats. ANESTHESIOLOGY 1995; 83:775-85
40. Abram SE, Yaksh TL: Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat. ANESTHESIOLOGY 1994; 80:383-91