Matrix metalloproteinases in medial arterial calcification: Potential mechanisms and actions

Vascular

Volumn 17, Issue SUPPL. 1, 2009, Pages

  Irwin, Chance L ^a   Guzman, Raul J ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Arterial calcification; Matrix metalloproteinases

Indexed keywords

COLLAGEN; ELASTIN; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTERY CALCIFICATION; DISEASE CONTROL; EXTRACELLULAR MATRIX; HUMAN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; REVIEW; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; ANIMAL; ANIMAL MODEL; ARTERIOSCLEROSIS; ARTERY; CALCINOSIS; ENZYMOLOGY; IMMUNOLOGY; INFLAMMATION; INTIMA; MOUSE; PATHOLOGY; PHYSIOLOGY; RAT;

ANIMALS; ARTERIES; ARTERIOSCLEROSIS; CALCINOSIS; EXTRACELLULAR MATRIX; HUMANS; INFLAMMATION; MATRIX METALLOPROTEINASES; MICE; MODELS, ANIMAL; RATS; TUNICA INTIMA;

EID: 70349234498     PISSN: 17085381     EISSN: None     Source Type: Journal    
DOI: 10.2310/6670.2008.00086     Document Type: Review

References (61)

1. Arad Y, Newstein D, Cadet F, et al. Association of multiple risk factors and insulin resistance with increased prevalence of asymptomatic coronary artery disease by an electron-beam computed tomographic study. Arterioscler Thromb Vasc Biol 2001;21:2051-8.
2. Chen NX, Moe SM. Vascular calcification in chronic kidney disease. Semin Nephrol 2004;24:61-8.
3. Wayhs R, Zelinger A, Raggi P. High coronary artery calcium scores pose an extremely elevated risk for hard events. J Am Coll Cardiol 2002;39:225-30.
4. Lehto S, Niskanen L, Suhonen M, et al. Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996;16:978-83.
5. Lehto S, Ronnemaa T, Pyorala K, Laakso M. Risk factors predicting lower extremity amputations in patients with NIDDM. Diabetes Care 1996;19:607-12.
6. Guzman RJ, Brinkley DM, Schumacher PM, et al. Tibial artery calcification as a marker of amputation risk in patients with peripheral arterial disease. J Am Coll Cardiol 2008;51:1967-74.
7. Abedin M, Tintut Y, Demer LL. Vascular calcification: mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol 2004;24: 1161-70.
8. Matrisian LM. Matrix metalloproteinase gene expression. Ann N Y Acad Sci 1994;732:42-50.
9. Martin MD, Matrisian LM. The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev 2007;26:717-24.
10. Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res 2002;90:251-62.
11. Bini A, Mann KG, Kudryk BJ, Schoen FJ. Noncollagenous bone matrix proteins, calcification, and thrombosis in carotid artery atherosclerosis. Arterioscler Thromb Vasc Biol 1999;19:1852-61.
12. Kieffer P, Giummelly P, Schjoth B, et al. Activation of metalloproteinase-2, loss of matrix scleroprotein content and coronary artery calcification. Atherosclerosis 2001;157:251-4.
13. Parks WC, Wilson CL, Lopez-Boado YS. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 2004;4:617-29.
14. Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation 2008;117:2938-48.
15. Demer LL, Tintut Y. Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture. Arterioscler Thromb Vasc Biol 2003;23:1739-43.
16. Shanahan CM, Cary NRB, Salisbury JR, et al. Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation 1999;100:2168-76.
17. Chen NX, Moe SM. Arterial calcification in diabetes. Curr Diab Rep 2003;3:28-32.
18. Leskinen Y, Salenius JP, Lehtimaki T, et al. The prevalence of peripheral arterial disease and medial arterial calcification in patients with chronic renal failure: requirements for diagnostics. Am J Kidney Dis 2002;40:472-9.
19. Llach F, Velasquez Forero F. Secondary hyperparathyroidism in chronic renal failure: pathogenic and clinical aspects. Am J Kidney Dis 2001;38(5 Suppl 5):S20-33.
20. Vattikuti R, Towler DA. Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab 2004;286:E686-96.
21. Shao J-S, Cai J, Towler DA. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol 2006;26:1423-30.
22. Dellegrottaglie S, Sanz J, Rajagopalan S. Molecular determinants of vascular calcification: a bench to bedside view. Curr Mol Med 2006;6:515-24.
23. Towler DA, Bidder M, Latifi T, et al. Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice. J Biol Chem 1998; 273:30427-34.
24. Tintut Y, Patel J, Territo M, et al. Monocyte/macrophage regulation of vascular calcification in vitro. Circulation 2002;105:650-5.
25. Zhang L, Zalewski A, Liu Y, et al. Diabetes-induced oxidative stress and low-grade inflammation in porcine coronary arteries. Circulation 2003;108:472-8.
26. Shao J-S, Aly Za, Lai C-F, et al. Vascular Bmp msx2 wnt signaling and oxidative stress in arterial calcification. Ann N Y Acad Sci 2007;1117:40-50.
27. Page-McCaw A, Ewald AJ, Werb Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol 2007;8: 221-33.
28. Mott JD, Werb Z. Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol 2004;16:558-64.
29. Faury G. Function-structure relationship of elastic arteries in evolution: from microfibrils to elastin and elastic fibres. Pathol Biol (Paris) 2001;49:310-25.
30. Urry DW. Neutral sites for calcium ion binding to elastin and collagen: a charge neutralization theory for calcification and its relationship to atherosclerosis. Proc Natl Acad Sci U S A 1971;68: 810-4.
31. Vyavahare N, Jones PL, Tallapragada S, Levy RJ. Inhibition of matrix metalloproteinase activity attenuates tenascin-C production and calcification of implanted purified elastin in rats. Am J Pathol 2000;157:885-93.
32. Vyavahare N, Ogle M, Schoen FJ, Levy RJ. Elastin calcification and its prevention with aluminum chloride pretreatment. Am J Pathol 1999;155:973-82.
33. Basalyga DM, Simionescu DT, Xiong W, et al. Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation 2004;110:3480-7.
34. Lee JS, Basalyga DM, Simionescu A, et al. Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. Am J Pathol 2006; 168:490-8.
35. Simionescu A, Philips K, Vyavahare N. Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells. Biochem Biophys Res Commun 2005;334:524-32.
36. Qin X, Corriere MA, Matrisian LM, Guzman RJ. Matrix metalloproteinase inhibition attenuates aortic calcification. Arterioscler Thromb Vasc Biol 2006;26:1510-6.
37. Price PA, Caputo JM, Williamson MK. Bone origin of the serum complex of calcium, phosphate, fetuin, and and matrix Gla protein: biochemical evidence for the cancellous bone-remodeling compartment. J Bone Miner Res 2002;17:1171-9.
38. Lomashvili KA, Cobbs S, Hennigar RA, et al. Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. J Am Soc Nephrol 2004;15:1392-401.
39. Bouvet C, Moreau S, Blanchette J, et al. Sequential activation of matrix metalloproteinase 9 and transforming growth factor {beta} in arterial elastocalcinosis. Arterioscler Thromb Vasc Biol 2008;28: 856-62.
40. Price PA, Faus SA, Williamson MK. Warfarin-induced artery calcification is accelerated by growth and vitamin D. Arterioscler Thromb Vasc Biol 2000;20:317-27.
41. Wang TJ, Larson MG, Levy D, et al. C-reactive protein is associated with subclinical epicardial coronary calcification inmen and women: the Framingham Heart Study. Circulation 2002;106:1189-91.
42. Stompor T, Pasowicz M, Sullowicz W, et al. An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis. Am J Kidney Dis 2003;41:203-11.
43. Doherty TM, Asotra K, Fitzpatrick LA, et al. Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads. Proc Natl Acad Sci U S A 2003;100:11201-6.
44. Colhoun HM, Schalkwijk C, Rubens MB, Stehouwer CD. C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification. Diabetes Care 2002;25:1813-7.
45. Reilly MP, Wolfe ML, Localio AR, Rader DJ. C-reactive protein and coronary artery calcification: the Study of Inherited Risk of Coronary Atherosclerosis (SIRCA). Arterioscler Thromb Vasc Biol 2003;23:1851-6.
46. Ishimura E, Okuno S, Kitatani K, et al. C-reactive protein is a significant predictor of vascular calcification of both aorta and hand arteries. Semin Nephrol 2004;24:408-12.
47. Aikawa E, Nahrendorf M, Figueiredo JL, et al. Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation 2007;116:2841-50.
48. Opdenakker G, Van den Steen PE, Van Damme J. Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol 2001; 22:571-9.
49. Schonbeck U, Mach F, Libby P. Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J Immunol 1998; 161:3340-6.
50. Gearing AJ, Beckett P, Christodoulou M, et al. Processing of tumour necrosis factor-alpha precursor by metalloproteinases. Nature 1994;370:555-7.
51. English WR, Puente XS, Freije JMP, et al. Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2. J Biol Chem 2000;275:14046-55.
52. Scatena M, Liaw L, Giachelli CM. Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 2007;27:2302-9.
53. Lai C-F, Seshadri V, Huang K, et al. An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circ Res 2006;98:1479-89.
54. Agnihotri R, Crawford HC, Haro H, et al. Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem 2001;276: 28261-7.
55. Hou P, Troen T, Ovejero MC, et al. Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption. Bone 2004;34:37-47.
56. Ortega N, Behonick D, Stickens D, Werb Z. How proteases regulate bone morphogenesis. Ann N Y Acad Sci 2003;995:109-16.
57. Mannello F, Tonti GA, Bagnara GP, Papa S. Role and function of matrix metalloproteinases in the differentiation and biological characterization of mesenchymal stem cells. Stem Cells 2006;24: 475-81.
58. Vu TH, Shipley JM, Bergers G, et al. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 1998;93:411-22.
59. Colnot C, Thompson Z, Miclau T, et al. Altered fracture repair in the absence of MMP9. Development 2003;130:4123-33.
60. Inada M, Wang Y, Byrne MH, et al. Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification. Proc Natl Acad Sci U S A 2004;101: 17192-7.
61. Behonick DJ, Xing Z, Lieu S, et al. Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PLoS ONE 2007;2: e1150.