LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs

Circulation Research

Volumn 105, Issue 6, 2009, Pages 549-556

  Gorovoy, Matvey ^a   Han, Jingyan ^a   Pan, Haiyun ^a   Welch, Emily ^a   Neamu, Radu ^a   Jia, Zhengping ^b   Predescu, Dan ^a   Vogel, Stephen ^a   Minshall, Richard D ^a   Ye, Richard D ^a   Malik, Asrar B ^a   Voyno Yasenetskaya, Tatyana ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Actin cytoskeleton; Acute lung injury; Endothelial barrier function; Inflammation; LIMK1; Neutrophil infiltration; RhoA

Indexed keywords

ENDOTOXIN; LIM KINASE 1; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; LIM KINASE; LIMK1 PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE, ESCHERICHIA COLI 0111 B4; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, MOUSE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; DISEASE SEVERITY; DOWN REGULATION; ENDOTHELIAL BARRIER DISRUPTION; ENDOTHELIUM CELL; LUNG; LUNG EDEMA; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMOTAXIS; DRUG EFFECT; ENDOTHELIUM; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; NEUTROPHIL; PATHOLOGY; SEPSIS;

ACUTE LUNG INJURY; ANIMALS; CHEMOTAXIS; ENDOTHELIUM; HUMANS; LIM KINASES; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; NEUTROPHILS; PULMONARY EDEMA; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SEPSIS;

EID: 70349229747     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.195883     Document Type: Article

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