VanA-type Staphylococcus aureus strain VRSA-7 is partially dependent on vancomycin for growth

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 9, 2009, Pages 3657-3663

  Moubareck, Carole ^a   Meziane Cherif, Djalal ^a   Courvalin, Patrice ^a   Périchon, Bruno ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BACTERIAL PROTEIN; GLYCOPEPTIDE; PEPTIDOGLYCAN; PROTEIN VANR; PROTEIN VANS; UNCLASSIFIED DRUG; VANCOMYCIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; ENZYME REGULATION; GENE CLUSTER; GENE MUTATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; GENES, BACTERIAL; GLYCOPEPTIDES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PEPTIDOGLYCAN; PLASMIDS; SEQUENCE HOMOLOGY, AMINO ACID; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 70349156393     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00338-09     Document Type: Article

References (41)

1. Aligholi, M., M. Emaneini, F. Jabalameli, S. Shahsavan, H. Dabiri, and H. Sedaght. 2008. Emergence of high-level vancomycin-resistant Staphylococcus aureus in the Imam Khomeini Hospital in Tehran. Med. Princ. Pract. 17:432-434.
2. Arthur, M., F. Depardieu, C. Molinas, P. Reynolds, and P. Courvalin. 1995. The vanZ gene of Tn1546 from Enterococcus faecium BM4147 confers resistance to teicoplanin. Gene 154:87-92.
3. Arthur, M., F. Depardieu, P. Reynolds, and P. Courvalin. 1996. Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci. Mol. Microbiol. 21:33-44.
4. Arthur, M., C. Molinas, and P. Courvalin. 1992. The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 174:2582-2591.
5. Arthur, M., C. Molinas, F. Depardieu, and P. Courvalin. 1993. Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 175:117-127. (Pubitemid 23016657)
6. Arthur, M., P. E. Reynolds, and P. Courvalin. 1996. Glycopeptide resistance in enterococci. Trends Microbiol. 4:401-407.
7. Bugg, T. D., S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Identification of vancomycin resistance protein VanA as a D-alanine: D-alanine ligase of altered substrate specificity. Biochemistry 30:2017-2021.
8. Casadewall, B., and P. Courvalin. 1999. Characterization of the vanD glycopeptide resistance gene cluster from Enterococcus faecium BM4339. J. Bacteriol. 181:3644-3648.
9. Comité de l' A ntibiogramme de la S ociété F rançaise de M icrobiologie. 2009. Communiqué 2009. Comité de l'Antibiogramme de la Société Française de Microbiologie, Paris, France. http://www.sfm.asso.fr.
10. Daub, E., L. E. Zawadzke, D. Botstein, and C. T. Walsh. 1988. Isolation, cloning, and sequencing of the Salmonella typhimurium ddlA gene with purification and characterization of its product, D-alanine:D-alanine ligase (ADP forming). Biochemistry 27:3701-3708.
11. Dejonge, B. L. M., Y. S. Chang, D. Gage, and A. Tomasz. 1992. Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. J. Biol. Chem. 267:11248-11254.
12. Depardieu, F., M. G. Bonora, P. E. Reynolds, and P. Courvalin. 2003. The vanG glycopeptide resistance operon from Enterococcus faecalis revisited. Mol. Microbiol. 50:931-948.
13. Depardieu, F., B. Perichon, and P. Courvalin. 2004. Detection of the van alphabet and identification of enterococci and staphylococci at the species level by multiplex PCR. J. Clin. Microbiol. 42:5857-5860.
14. Dever, L. L., S. M. Smith, S. Handwerger, and R. H. K. Eng. 1995. Vancomycin- dependent Enterococcus faecium isolated from stool following oral vancomycin therapy. J. Clin. Microbiol. 33:2770-2773.
15. Dyke, K. G., M. P. Jevons, and M. T. Parker. 1966. Penicillinase production and intrinsic resistance to penicillins in Staphylococcus aureus. Lancet i:835-838.
16. Farrag, N., I. Eltringham, and H. Liddy. 1996. Vancomycin-dependent Enterococcus faecalis. Lancet 348:1581-1582.
17. Fox, P. M., R. J. Lampert, K. S. Stumpf, G. L. Archer, and M. W. Climo. 2006. Successful therapy of experimental endocarditis caused by vancomycin- resistant Staphylococcus aureus with a combination of vancomycin and β-lactam antibiotics. Antimicrob. Agents Chemother. 50:2951-2956.
18. Greisen, K., M. Loeffelholz, A. Purohit, and D. Leong. 1994. PCR primers and probes for the 16S rRNA gene of most species of pathogenic bacteria, including bacteria found in cerebrospinal fluid. J. Clin. Microbiol. 32:335-351.
19. Jacob, A. E., and S. J. Hobbs. 1974. Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. J. Bacteriol. 117:360-372.
20. Kobayashi, N., M. Alam, Y. Nishimoto, S. Urasawa, N. Uehara, and N. Watanabe. 2001. Distribution of aminoglycoside resistance genes in recent clinical isolates of Enterococcus faecalis, Enterococcus faecium and Enterococcus avium. Epidemiol. Infect. 126:197-204. (Pubitemid 32454730)
21. Kreiswirth, B. N., S. Lofdahl, M. J. Betley, M. O'Reilly, P. M. Schlievert, M. S. Bergdoll, and R. P. Novick. 1983. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:709-712.
22. Lessard, I. A., V. L. Healy, I. S. Park, and C. T. Walsh. 1999. Determinants for differential effects on D-Ala-D-lactate vs D-Ala-D-Ala formation by the VanA ligase from vancomycin-resistant enterococci. Biochemistry 38:14006-14022.
23. Liu, S., J. S. Chang, J. T. Herberg, M. M. Horng, P. K. Tomich, A. H. Lin, and K. R. Marotti. 2006. Allosteric inhibition of Staphylococcus aureus Dalanine: D-alanine ligase revealed by crystallographic studies. Proc. Natl. Acad. Sci. USA 103:15178-15183.
24. Messer, J., and P. E. Reynolds. 1992. Modified peptidoglycan precursors produced by glycopeptide-resistant enterococci. FEMS Microbiol. Lett. 94:195-200.
25. Miller, D., V. Urdaneta, A. Weltman, and S. Park. 2002. Vancomycin-resistant Staphylococcus aureus. MMWR Morb. Mortal. Wkly. Rep. 51:902.
26. Neuhaus, F. C. 1962. The enzymatic synthesis of D-alanyl-D-alanine. II. Kinetic studies on D-alanyl-D-alanine synthase. J. Biol. Chem. 237:3128-3135.
27. O'Hara, D. M., and P. E. Reynolds. 1987. Antibody used to identify penicillin- binding protein 2′ in methicillin-resistant strains of Staphylococcus aureus (MRSA). FEBS Lett. 212:237-241.
28. Peirson, S. N., J. N. Butler, and R. G. Foster. 2003. Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res. 31:73.
29. Périchon, B., and P. Courvalin. 2006. Synergism between beta-lactams and glycopeptides against VanA-type methicillin-resistant Staphylococcus aureus and heterologous expression of the vanA operon. Antimicrob. Agents Chemother. 50:3622-3630. (Pubitemid 44684873)
30. Périchon, B., P. Reynolds, and P. Courvalin. 1997. VanD-type glycopeptide- resistant Enterococcus faecium BM4339. Antimicrob. Agents Chemother. 41:2016-2018.
31. Reynolds, P. E., and C. Fuller. 1986. Methicillin-resistant strains of Staphylococcus aureus; presence of identical additional penicillin-binding protein in all strains examined. FEMS Microbiol. Lett. 33:251-254.
32. Saha, B., A. K. Singh, A. Ghosh, and M. Bal. 2008. Identification and characterization of a vancomycin-resistant Staphylococcus aureus isolated from Kolkata (South Asia). J. Med. Microbiol. 57:72-79.
33. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
34. Schmitz, F. J., A. C. Fluit, M. Gondolf, R. Beyrau, E. Lindenlauf, J. Verhoef, H. P. Heinz, and M. E. Jones. 1999. The prevalence of aminoglycoside resistance and corresponding resistance genes in clinical isolates of staphylococci from 19 European hospitals. J. Antimicrob. Chemother. 43:253-259.
35. Severin, A., K. Tabei, F. Tenover, M. Chung, N. Clarke, and A. Tomasz. 2004. High level oxacillin and vancomycin resistance and altered cell wall composition in Staphylococcus aureus carrying the staphylococcal mecA and the enterococcal vanA gene complex. J. Biol. Chem. 279:3398-3407. (Pubitemid 38140576)
36. Sievert, D. M., M. L. Boulton, G. Stolman, D. Johnson, M. G. Stobierski, F. P. Downes, P. A. Somsel, J. T. Rudrik, W. Brown, W. Hafeez, T. Lundstrom, E. Flanagan, R. Johnson, J. Mitchell, and S. Chang. 2002. Staphylococcus aureus resistant to vancomycin. MMWR Morb. Mortal. Wkly. Rep. 51:565-567.
37. Sievert, D. M., J. T. Rudrik, J. B. Patel, L. C. McDonald, M. J. Wilkins, and J. C. Hageman. 2008. Vancomycin-resistant Staphylococcus aureus in the United States, 2002-2006. Clin. Infect. Dis. 46:668-674.
38. Sifaoui, F., and L. Gutmann. 1997. Vancomycin dependence in a VanA-producing Enterococcus avium strain with a nonsense mutation in the natural D-Ala-D-Ala ligase gene. Antimicrob. Agents Chemother. 41:1409.
39. Van Bambeke, F., M. Chauvel, P. E. Reynolds, H. S. Fraimow, and P. Courvalin. 1999. Vancomycin-dependent Enterococcus faecalis clinical isolates and revertant mutants. Antimicrob. Agents Chemother. 43:41-47.
40. Werner, G., R. J. Willems, B. Hildebrandt, I. Klare, and W. Witte. 2003. Influence of transferable genetic determinants on the outcome of typing methods commonly used for Enterococcus faecium. J. Clin. Microbiol. 41:1499-1506. (Pubitemid 36428095)
41. Zhu, W., N. C. Clark, L. K. McDougal, J. Hageman, L. C. McDonald, and J. B. Patel. 2008. Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. Antimicrob. Agents Chemother. 52:452-457.