Characterization of the vanD glycopeptide resistance gene cluster from Enterococcus faecium BM4339

Journal of Bacteriology

Volumn 181, Issue 12, 1999, Pages 3644-3648

  Casadewall, Barbara ^a   Courvalin, Patrice ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMPICILLIN; CARBOXYPEPTIDASE; DIPEPTIDASE; GLYCOPEPTIDE; KANAMYCIN; LIGASE; OXIDOREDUCTASE; PENICILLIN BINDING PROTEIN; PEPTIDOGLYCAN; SPECTINOMYCIN; STREPTOMYCIN; TEICOPLANIN; VANCOMYCIN;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS SUBTILIS; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; GENE CLUSTER; GENE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECOMBINANT PLASMID; STREPTOMYCES;

ENTEROCOCCUS FAECIUM;

EID: 0033011933     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.12.3644-3648.1999     Document Type: Article

References (37)

1. Arthur, M., et al. Unpublished data.
2. Arthur, M., F. Depardieu, L. Cabanié, P. Reynolds, and P. Courvalin. 1998. Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci. Mol. Microbiol. 31:819-830.
3. Arthur, M., F. Depardieu, G. Gerbaud, M. Galimand, R. Leclercq, and P. Courvalin. 1997. The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J. Bacteriol. 179:97-106.
4. Arthur, M., F. Depardieu, H. A. Snaith, P. E. Reynolds, and P. Courvalin. 1994. Contribution of VanY DD-carboxypeptidase to grycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors. Antimicrob. Agents Chemother. 38:1899-1903.
5. Arthur, M., C. Molinas, and P. Courvalin. 1992. Sequence of the vanY gene required for production of a vancomycin-inducible D,D-carboxypeptidase in Enterococcus faecium BM4147. Gene 120:111-114.
6. Arthur, M., C. Molinas, and P. Courvalin. 1992. The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 174:2582-2591.
7. Arthur, M., P. Reynolds, and P. Courvalin. 1996. Glycopeptide resistance in enterococci. Trends Microbiol. 4:401-407.
8. Baptista, M., F. Depardieu, P. Reynolds, P. Courvalin, and M. Arthur. 1997. Mutations leading to increased levels of resistance to glycopeptide antibiotics in VanB-type enterococci. Mol. Microbiol. 25:93-105.
9. Billot-Klein, D., L. Gutmann, S. Sablé, E. Guittet, and J. van Heijenoort. 1994. Modification of peptidoglycan precursors is a common feature of the low-level vancomycin-resistant VANB-type Enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Enterococcus gallinarum. J. Bacteriol. 176:2398-2405.
10. Broome-Smith, J. K., I. Ioannidis, A. Edelman, and B. G. Spratt. 1988. Nucleotide sequences of the penicillin-binding protein 5 and 6 genes of Escherichia coli. Nucleic Acids Res. 16:1617.
11. Bugg, T. D. H., S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Identification of vancomycin resistance protein VanA as a D-alanine: D-alanine ligase of altered substrate specificity. Biochemistry 30:2017-2021.
12. Bugg, T. D. H., G. D. Wright, S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry 30:10408-10415.
13. Churchward, G., D. Belin, and Y. Nagamine. 1984. A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors. Gene 31:165-171.
14. Evers, S., B. Casadewall, M. Charles, S. Dutka-Malen, M. Galimand, and P. Courvalin. 1996. Evolution of structure and substrate specificity in D-alanine: D-alanine ligases and related enzymes. J. Mol. Evol. 42:706-712.
15. B two-component regulatory system in Enterococcus faecalis V583. J. Bacteriol. 178:1302-1309.
16. Gholizadeh, Y., et al. Unpublished data.
17. Goudreau, P. N., and A. M. Stock. 1998. Signal transduction in bacteria: molecular mechanisms of stimulus-response coupling. Curr. Opin. Microbiol. 1:160-169.
18. Leclercq, R., E. Derlot, J. Duval, and P. Courvalin. 1988. Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N. Engl. J. Med. 319:157-161.
19. McCafferty, D. G., I. A. Lessard, and C. T. Walsh. 1997. Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX. Biochemistry 36:10498-10505.
20. Meziane-Cherif, D., M. A. Badet-Denisot, S. Evers, P. Courvalin, and B. Badet. 1994. Purification and characterization of the VanB ligase associated with type B vancomycin resistance in Enterococcus faecalis V583. FEBS Lett. 354:140-142.
21. Ostrowsky, B., N. Clark, C. T. Eliopoulos, L. Venkataraman, M. Samore, F. Tenover, G. M. Ellopoulos, R. C. Moellering, Jr., and H. S. Gold. 1998. A cluster of VanD glycopeptide-resistant (GR) Enterococcus faecium (Efcm): molecular characterization and clinical epidemiology, abstr. C-96, p. 96. In Abstracts of the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
22. Palomeque-Messia, P., S. Englebert, M. Leyh-Bouille, M. Nguyen-Distèche, C. Duez, S. Houba, O. Dideberg, J. Van Beeumen, and J. M. Ghuysen. 1991. Amino acid sequence of the penicillin-binding protein/D,D-peptidase of Streptomyces K15. Biochem. J. 279:223-230.
23. Parkinson, J., and E. Kofoid. 1992. Communication modules in bacterial signaling proteins. Annu. Rev. Genet. 26:71-112.
24. Périchon, B., P. Reynolds, and P. Courvalin. 1997. VanD-type glycopeptide-resistant Enterococcus faecium BM4339. Antimicrob. Agents Chemother. 41:2016-2018.
25. Reynolds, P. E. 1989. Structure, biochemistry and mechanism of action of glycopeptide antibiotics. Eur. J. Clin. Microbiol. Infect. Dis. 8:943-950.
26. Reynolds, P. E., F. Depardieu, S. Dutka-Malen, M. Arthur, and P. Courvalin. 1994. Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine. Mol. Microbiol. 13:1065-1070.
27. Rosato, A., J. Pierre, D. Billot-Klein, A. Buu-Hoi, and L. Gutmann. 1995. Inducible and constitutive expression of resistance to glycopeptides and vancomycin dependence in glycopeptide-resistant Enterococcus avium. Antimicrob. Agents Chemother. 39:830-833.
28. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
29. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
30. Shepard, B. D., and M. S. Gilmore. 1995. Electroporation and efficient transformation of Enterococcus faecalis grown in high concentrations of glycine. Methods Mol. Biol. 47:217-226.
31. Sifaoui, F., and L. Gutmann. 1997. Vancomycin dependence in a VanA-producing Enterococcus avium strain with a nonsense mutation in the natural D-Ala-D-Ala ligase gene. Antimicrob. Agents Chemother. 41:1409.
32. Steers, E., E. L. Foltz, B. S. Graves, and J. Rindel. 1959. An inocula replicating apparatus for routine testing of bacterial susceptibility to antibiotics. Antibiot. Chemother. (Basel) 9:307-311.
33. Stoll, V. S., M. S. Kimber, and E. F. Pai. 1996. Insights into substrate binding by D-2-ketoacid dehydrogenases from the structure of Lactobacillus pentosus D-lactate dehydrogenase. Structure 4:437-447.
34. Van Bambeke, F., M. Chauvel, P. E. Reynolds, H. S. Fraimow, and P. Courvalin. 1999. Vancomycin-dependent Enterococcus faecalis clinical isolates and revertant mutants. Antimicrob. Agents Chemother. 43:41-47.
35. Vieira, J., and J. Messing. 1982. The pUC plasmids and M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene 19:259-268.
36. Wu, J.-J., R. Schuch, and P. J. Piggot 1992. Characterization of a Bacillus subtilis sporulation operon that includes genes for an RNA polymerase σ factor and for a putative DD-carboxypeptidase. J. Bacteriol. 174:4885-4892.
37. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.