-
1
-
-
3342958748
-
Reovirus oncolysis: The Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection
-
Norman KL, Hirasawa K, Yang AD, Shields MA and Lee PW: Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection. Proc Natl Acad Sci USA 101: 11099-11104, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11099-11104
-
-
Norman, K.L.1
Hirasawa, K.2
Yang, A.D.3
Shields, M.A.4
Lee, P.W.5
-
2
-
-
0002402597
-
Reovirus infections in human volunteers
-
Rosen L, Evans HE and Spickard A: Reovirus infections in human volunteers. Am J Hyg 77: 29-37, 1963.
-
(1963)
Am J Hyg
, vol.77
, pp. 29-37
-
-
Rosen, L.1
Evans, H.E.2
Spickard, A.3
-
4
-
-
0018083242
-
Differential sensitivity of normal and transformed human cells to reovirus infection
-
Duncan MR, Stanish SM and Cox DC: Differential sensitivity of normal and transformed human cells to reovirus infection. J Virol 28: 444-449, 1978.
-
(1978)
J Virol
, vol.28
, pp. 444-449
-
-
Duncan, M.R.1
Stanish, S.M.2
Cox, D.C.3
-
5
-
-
0017735838
-
The preferential cytotoxicity of reovirus for certain transformed cell lines
-
Hashiro G, Loh PC and Yau JT: The preferential cytotoxicity of reovirus for certain transformed cell lines. Arch Virol 54: 307-315, 1977.
-
(1977)
Arch Virol
, vol.54
, pp. 307-315
-
-
Hashiro, G.1
Loh, P.C.2
Yau, J.T.3
-
6
-
-
0032515141
-
Reovirus therapy of tumors with activated Ras pathway
-
Coffey MC, Strong JE, Forsyth PA and Lee PW: Reovirus therapy of tumors with activated Ras pathway. Science 282: 1332-1334, 1998.
-
(1998)
Science
, vol.282
, pp. 1332-1334
-
-
Coffey, M.C.1
Strong, J.E.2
Forsyth, P.A.3
Lee, P.W.4
-
7
-
-
0032526693
-
The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
-
Strong JE, Coffey MC, Tang D, Sabinin P and Lee PW: The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO J 17: 3351-3362, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 3351-3362
-
-
Strong, J.E.1
Coffey, M.C.2
Tang, D.3
Sabinin, P.4
Lee, P.W.5
-
8
-
-
0037439809
-
Systemic reovirus therapy of metastatic cancer in immune-competent mice
-
Hirasawa K, Nishikawa SG, Norman KL, Coffey MC, Thompson BG, Yoon CS, Waisman DM and Lee PW: Systemic reovirus therapy of metastatic cancer in immune-competent mice. Cancer Res 63: 348-353, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 348-353
-
-
Hirasawa, K.1
Nishikawa, S.G.2
Norman, K.L.3
Coffey, M.C.4
Thompson, B.G.5
Yoon, C.S.6
Waisman, D.M.7
Lee, P.W.8
-
9
-
-
65049086331
-
Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells
-
In press
-
Park EH, Koh SS, Srisuttee R, Cho IR, Min HJ, Jhun BH, Lee YS, Jang KL, Kim CH, Johnston RN and Chung YH: Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells. Cancer Gene Ther (In press).
-
Cancer Gene Ther
-
-
Park, E.H.1
Koh, S.S.2
Srisuttee, R.3
Cho, I.R.4
Min, H.J.5
Jhun, B.H.6
Lee, Y.S.7
Jang, K.L.8
Kim, C.H.9
Johnston, R.N.10
Chung, Y.H.11
-
10
-
-
19944427873
-
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: Racine and nonhuman primates
-
Yang WQ, Lun X, Palmer CA, Wilcox ME, Muzik H, Shi ZQ, Dyck R, Coffey M, Thompson B, Hamilton M, Nishikawa SG, Brasher PM, Fonseca K, George D, Rewcastle NB, Johnston RN, Stewart D, Lee PW, Senger DL and Forsyth PA: Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates. Clin Cancer Res 10: 8561-8576, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8561-8576
-
-
Yang, W.Q.1
Lun, X.2
Palmer, C.A.3
Wilcox, M.E.4
Muzik, H.5
Shi, Z.Q.6
Dyck, R.7
Coffey, M.8
Thompson, B.9
Hamilton, M.10
Nishikawa, S.G.11
Brasher, P.M.12
Fonseca, K.13
George, D.14
Rewcastle, N.B.15
Johnston, R.N.16
Stewart, D.17
Lee, P.W.18
Senger, D.L.19
Forsyth, P.A.20
more..
-
11
-
-
20444496370
-
Not all viruses are bad guys: The case for reovirus in cancer therapy
-
Norman KL and Lee PW: Not all viruses are bad guys: the case for reovirus in cancer therapy. Drug Discov Today 10: 847-855, 2005.
-
(2005)
Drug Discov Today
, vol.10
, pp. 847-855
-
-
Norman, K.L.1
Lee, P.W.2
-
12
-
-
0037085930
-
Oncolytic reovirus against ovarian and colon cancer
-
Hirasawa K, Nishikawa SG, Norman KL, Alain T, Kossakowska A and Lee PW: Oncolytic reovirus against ovarian and colon cancer. Cancer Res 62: 1696-1701, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 1696-1701
-
-
Hirasawa, K.1
Nishikawa, S.G.2
Norman, K.L.3
Alain, T.4
Kossakowska, A.5
Lee, P.W.6
-
13
-
-
9644252745
-
Reovirus oncolysis in human head and neck squamous carcinoma cells
-
Ikeda Y, Nishimura G, Yanoma S, Kubota A, Furukawa M and Tsukuda M: Reovirus oncolysis in human head and neck squamous carcinoma cells. Auris Nasus Larynx 31: 407-412, 2004.
-
(2004)
Auris Nasus Larynx
, vol.31
, pp. 407-412
-
-
Ikeda, Y.1
Nishimura, G.2
Yanoma, S.3
Kubota, A.4
Furukawa, M.5
Tsukuda, M.6
-
14
-
-
34447125800
-
Reovirus decreases azoxymethane-induced aberrant crypt foci and colon cancer in a rodent model
-
Alain T, Wong JF, Endersby R, Urbanski SJ, Lee PW, Muruve DA, Johnston RN, Forsyth PA and Beck PL: Reovirus decreases azoxymethane-induced aberrant crypt foci and colon cancer in a rodent model. Cancer Gene Ther 14: 867-872, 2007.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 867-872
-
-
Alain, T.1
Wong, J.F.2
Endersby, R.3
Urbanski, S.J.4
Lee, P.W.5
Muruve, D.A.6
Johnston, R.N.7
Forsyth, P.A.8
Beck, P.L.9
-
15
-
-
0033881830
-
Reovirus-induced apoptosis is mediated by TRAIL
-
Clarke P, Meintzer SM, Gibson S, Widmann C, Garrington TP, Johnson GL and Tyler KL: Reovirus-induced apoptosis is mediated by TRAIL. J Virol 74: 8135-8139, 2000.
-
(2000)
J Virol
, vol.74
, pp. 8135-8139
-
-
Clarke, P.1
Meintzer, S.M.2
Gibson, S.3
Widmann, C.4
Garrington, T.P.5
Johnson, G.L.6
Tyler, K.L.7
-
16
-
-
0035164662
-
Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun
-
Clarke P, Meintzer SM, Widmann C, Johnson GL and Tyler KL: Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun. J Virol 75: 11275-11283, 2001.
-
(2001)
J Virol
, vol.75
, pp. 11275-11283
-
-
Clarke, P.1
Meintzer, S.M.2
Widmann, C.3
Johnson, G.L.4
Tyler, K.L.5
-
17
-
-
0035909512
-
Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection
-
Clarke P, Meintzer SM, Spalding AC, Johnson GL and Tyler KL: Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection. Oncogene 20: 6910-6919, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 6910-6919
-
-
Clarke, P.1
Meintzer, S.M.2
Spalding, A.C.3
Johnson, G.L.4
Tyler, K.L.5
-
18
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S and Cohen P: GSK3 takes centre stage more than 20 years after its discovery. Biochem J 359: 1-16, 2001.
-
(2001)
Biochem J
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
19
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett JR: Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 9: 2431-2438, 1990.
-
(1990)
EMBO J
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
20
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble BW and Woodgett JR: GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116: 1175-1186, 2003.
-
(2003)
J Cell Sci
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
21
-
-
0030978351
-
Betacatenin is a target for the ubiquitin-proteasome pathway
-
Aberle H, Bauer A, Stappert J, Kispert A and Kemler R: Betacatenin is a target for the ubiquitin-proteasome pathway. EMBO J 16: 3797-3804, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
22
-
-
23044444841
-
Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
-
Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, Mai M, Takahashi Y and Minamoto T: Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 334: 1365-1373, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1365-1373
-
-
Shakoori, A.1
Ougolkov, A.2
Yu, Z.W.3
Zhang, B.4
Modarressi, M.H.5
Billadeau, D.D.6
Mai, M.7
Takahashi, Y.8
Minamoto, T.9
-
23
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O and Woodgett JR: Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406: 86-90, 2000.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
24
-
-
0036891871
-
Reovirus therapy of lymphoid malignancies
-
Alain T, Hirasawa K, Pon KJ, Nishikawa SG, Urbanski SJ, Auer Y, Luider J, Martin A, Johnston RN, Janowska-Wieczorek A, Lee PW and Kossakowska AE: Reovirus therapy of lymphoid malignancies. Blood 100: 4146-4153, 2002.
-
(2002)
Blood
, vol.100
, pp. 4146-4153
-
-
Alain, T.1
Hirasawa, K.2
Pon, K.J.3
Nishikawa, S.G.4
Urbanski, S.J.5
Auer, Y.6
Luider, J.7
Martin, A.8
Johnston, R.N.9
Janowska-Wieczorek, A.10
Lee, P.W.11
Kossakowska, A.E.12
-
25
-
-
34250338921
-
Acquired resistance to reoviral oncolysis in Rastransformed fibrosarcoma cells
-
Kim M, Egan C, Alain T, Urbanski SJ, Lee PW, Forsyth PA and Johnston RN: Acquired resistance to reoviral oncolysis in Rastransformed fibrosarcoma cells. Oncogene 26: 4124-4134, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 4124-4134
-
-
Kim, M.1
Egan, C.2
Alain, T.3
Urbanski, S.J.4
Lee, P.W.5
Forsyth, P.A.6
Johnston, R.N.7
-
26
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam JD, Lebovitz RM and Roeder RG: Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489, 1983.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
27
-
-
0034254811
-
The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells
-
Ardeshna KM, Pizzey AR, Devereux S and Khwaja A: The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 96: 1039-1046, 2000.
-
(2000)
Blood
, vol.96
, pp. 1039-1046
-
-
Ardeshna, K.M.1
Pizzey, A.R.2
Devereux, S.3
Khwaja, A.4
-
28
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein PS and Melton DA: A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 93: 8455-8459, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
29
-
-
16844374033
-
Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells
-
Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA and Billadeau DD: Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 65: 2076-2081, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 2076-2081
-
-
Ougolkov, A.V.1
Fernandez-Zapico, M.E.2
Savoy, D.N.3
Urrutia, R.A.4
Billadeau, D.D.5
-
30
-
-
33847780441
-
Colorectal cancer screening: Its time for action in Asia
-
Sung J: Colorectal cancer screening: its time for action in Asia. Cancer Detect Prev 31: 1-2, 2007.
-
(2007)
Cancer Detect Prev
, vol.31
, pp. 1-2
-
-
Sung, J.1
-
31
-
-
0034830884
-
Analysis of K-ras, APC, and beta-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis
-
Takayama T, Ohi M, Hayashi T, Miyanishi K, Nobuoka A, Nakajima T, Satoh T, Takimoto R, Kato J, Sakamaki S and Niitsu Y: Analysis of K-ras, APC, and beta-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis. Gastroenterology 121: 599-611, 2001.
-
(2001)
Gastroenterology
, vol.121
, pp. 599-611
-
-
Takayama, T.1
Ohi, M.2
Hayashi, T.3
Miyanishi, K.4
Nobuoka, A.5
Nakajima, T.6
Satoh, T.7
Takimoto, R.8
Kato, J.9
Sakamaki, S.10
Niitsu, Y.11
-
33
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson WJ and Nusse R: Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487, 2004.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
34
-
-
3042635178
-
GSK3 inhibitors: Development and therapeutic potential
-
Cohen P and Goedert M: GSK3 inhibitors: development and therapeutic potential. Nat Rev Drug Discov 3: 479-487, 2004.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 479-487
-
-
Cohen, P.1
Goedert, M.2
-
35
-
-
34547782316
-
Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents
-
Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K and Minamoto T: Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents. Cancer Sci 98: 1388-1393, 2007.
-
(2007)
Cancer Sci
, vol.98
, pp. 1388-1393
-
-
Shakoori, A.1
Mai, W.2
Miyashita, K.3
Yasumoto, K.4
Takahashi, Y.5
Ooi, A.6
Kawakami, K.7
Minamoto, T.8
-
36
-
-
0037853146
-
Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/ extracellular signal-regulated kinase kinase kinase 1 (MEKK1)
-
Kim JW, Lee JE, Kim MJ, Cho EG, Cho SG and Choi EJ: Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/ extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J Biol Chem 278: 13995-14001, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 13995-14001
-
-
Kim, J.W.1
Lee, J.E.2
Kim, M.J.3
Cho, E.G.4
Cho, S.G.5
Choi, E.J.6
-
37
-
-
4544341116
-
Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor
-
Takada Y, Fang X, Jamaluddin MS, Boyd DD and Aggarwal BB: Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J Biol Chem 279: 39541-39554, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 39541-39554
-
-
Takada, Y.1
Fang, X.2
Jamaluddin, M.S.3
Boyd, D.D.4
Aggarwal, B.B.5
|