Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord

Journal of Neuroscience

Volumn 29, Issue 37, 2009, Pages 11601-11613

  Kwan, Alex C ^a   Dietz, Shelby B ^b   Webb, Watt W ^a   Harris Warrick, Ronald M ^b  

^a Cornell University   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CALCIUM; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MOTILITY; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; GENETIC IDENTIFICATION; IN VITRO STUDY; INTERNEURON; ISOLATION PROCEDURE; MEMBRANE POTENTIAL; MOTONEURON; MOUSE; NERVE CELL; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SPINAL CORD; VENTRAL ROOT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CALCIUM; DOPAMINE; ELECTRIC STIMULATION; FUNCTIONAL LATERALITY; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; INTERNEURONS; LOCOMOTION; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; N-METHYLASPARTATE; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; SEROTONIN; SPINAL CORD; SPINAL NERVE ROOTS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 70349148249     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1612-09.2009     Document Type: Article

References (44)

1. Arber S, Han B, Mendelsohn M, Smith M, Jessell TM, Sockanathan S (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 23:659-674. (Pubitemid 29411557)
2. Berkowitz A, Stein PSG (1994) Activity of descending propriospinal axons in the turtle hindlimb enlargement during two forms of fictive scratching: phase analyses. J Neurosci 14:5105-5119. (Pubitemid 24237928)
3. Bonnot A, Whelan PJ, Mentis GZ, O'Donovan MJ (2002) Spatiotemporal pattern of motoneuron activation in the rostral lumbar and the sacral segments during locomotor-like activity in the neonatal mouse spinal cord. J Neurosci 22:RC203(1-6).
4. Bonnot A, Mentis GZ, Skoch J, O'Donovan MJ (2005) Electroporation loading of calcium-sensitive dyes into the CNS. J Neurophysiol 93:1793-1808. (Pubitemid 40283756)
5. Brownstone RM, Wilson JM (2008) Strategies for delineating spinal locomotor rhythm-generating networks and the possible role of Hb9 interneurons in rhythmogenesis. Brain Res Rev 57:64-76.
6. Cuellar CA, Tapia JA, Juárez V, Quevedo J, Linares P, Martínez L, Manjarrez E (2009) Propagation of sinusoidal electrical waves along the spinal cord during a fictive motor task. J Neurosci 29:798-810.
7. Denk W, Strickler JH, Webb WW (1990) Two-photon laser scanning fluorescence microscopy. Science 248:73-76. (Pubitemid 20139273)
8. Feldman JL, Del Negro CA (2006) Looking for inspiration: new perspective on respiratory rhythm. Nat Rev Neurosci 7:232-242.
9. Fetcho JR, Higashijima S, McLean DL (2008) Zebrafish and motor control over the last decade. Brain Res Rev 57:86-93. (Pubitemid 350218166)
10. Garaschuk O, Milos RI, Konnerth A (2006) Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo. Nat Protoc 1:380-386.
11. Gordon IT, Whelan PJ (2006) Monoaminergic control of cauda-equinaevoked locomotion in the neonatal mouse spinal cord. J Neurophysiol 96:3122-3129.
12. Grillner S (2003) The motor infrastructure: from ion channels to neuronal networks. Nat Rev Neurosci 4:573-586. (Pubitemid 37279129)
13. Han P, Nakanishi ST, Tran MA, Whelan PJ (2007) Dopaminergic modulation of spinal neuronal excitability. J Neurosci 27:13192-13204. (Pubitemid 350220482)
14. Hinckley CA, Ziskind-Conhaim L (2006) Electrical coupling between locomotor-related excitatory interneurons in the mammalian spinal cord. J Neurosci 26:8477-8483.
15. Hinckley CA, Hartley R, Wu L, Todd A, Ziskind-Conhaim L (2005) Locomotor-like rhythms in a genetically distinct cluster of interneurons in the mammalian spinal cord. J Neurophysiol 93:1439-1449. (Pubitemid 40283732)
16. Jiang Z, Rempel J, Li J, Sawchuk MA, Carlin KP, Brownstone RM (1999) Development of L-type calcium channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord. Eur J Neurosci 11:3481-3487. (Pubitemid 29484245)
17. Kerr JN, Greenberg D, Helmchen F (2005) Imaging input and output of neocortical networks in vivo. Proc Natl Acad Sci U S A 102:14063-14068. (Pubitemid 41377703)
18. Kiehn O (2006) Locomotor circuits in the mammalian spinal cord. Annu Rev Neurosci 29:279-306.
19. Kjaerulff O, Kiehn O (1996) Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study. J Neurosci 16:5777-5794. (Pubitemid 26293400)
20. Kudo N, Yamada T (1987) N-methyl-D,L-aspartate-induced locomotor activity in a spinal cord-hindlimb muscle preparation of the newborn rat studied in vitro. Neurosci Lett 75:43-48.
21. Lafreniere-Roula M, McCrea DA (2005) Deletions of rhythmic motoneuron activity during fictive locomotion and scratch provide clues to the organization of the mammalian central pattern generator. J Neurophysiol 94:1120-1132. (Pubitemid 41061353)
22. Lev-Tov A, Delvolvé I, Kremer E (2000) Sacrocaudal afferents induce rhythmic efferent bursting in isolated spinal cords of neonatal rats. J Neurophysiol 83:888-894. (Pubitemid 30091298)
23. Marder E, Bucher D (2001) Central pattern generators and the control of rhythmic movements. Curr Biol 11:R986-R996. (Pubitemid 33141419)
24. Marder E, Bucher D (2007) Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs. Annu Rev Physiol 69:291-316. (Pubitemid 46457645)
25. Markram H, Helm PJ, Sakmann B (1995) Dendritic calcium transients evoked by single back-propagating action potentials in rat neocortical pyramidal neurons. J Physiol 485:1-20.
26. McCrea DA, Rybak IA (2008) Organization of mammalian locomotor rhythm and pattern generation. Brian Res Rev 57:134-146.
27. Roberts A, Soffe SR, Wolf ES, Yoshida M, Zhao FY (1998) Central circuits controlling locomotion in young frog tadpoles. Ann N Y Acad Sci 860:19-34. (Pubitemid 29045957)
28. Rybak IA, Shevtsova NA, Lafreniere-Roula M, McCrea DA (2006a) Modelling spinal circuitry involved in locomotor pattern generation: insights from deletions during fictive locomotion. J Physiol 577:617-639. (Pubitemid 44804017)
29. Rybak IA, Stecina K, Shevtsova NA, McCrea DA (2006b) Modelling spinal circuitry involved in locomotor pattern generation: insights from the effects of afferent stimulation. J Physiol 577:641-658. (Pubitemid 44804018)
30. Sato TR, Gray NW, Mainen ZF, Svoboda K (2007) The functional microarchitecture of the mouse barrel cortex. PLoS Biol 5:e189.
31. Sillar KT, Reith CA, McDearmid JR (1998) Development and aminergic neuromodulation of a spinal locomotor network controlling swimming in Xenopus larvae. Ann N Y Acad Sci 860:318-332.
32. Stosiek C, Garaschuk O, Holthoff K, Konnerth A (2003) In vivo two-photon calcium imaging of neuronal networks. Proc Natl Acad Sci U S A 100:7319-7324.
33. Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, Pfaff SL (1999) Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor Hb9. Neuron 23:675-687. (Pubitemid 29411558)
34. Whelan P, Bonnot A, O'Donovan MJ (2000) Properties of rhythmic activity generated by the isolated spinal cord of the neonatal mouse. J Neurophysiol 84:2821-2833.
35. Wichterle H, Lieberam I, Porter JA, Jessell TM (2002) Directed differentiation of embryonic stem cells into motor neurons. Cell 110:385-397. (Pubitemid 34899386)
36. Wilson JM, Hartley R, Maxwell DJ, Todd AJ, Lieberam I, Kaltschmidt JA, Yoshida Y, Jessell TM, Brownstone RM (2005) Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci 25:5710-5719. (Pubitemid 40847883)
37. Wilson JM, Cowan AI, Brownstone RM (2007a) Heterogeneous electrotonic coupling and synchronization of rhythmic bursting activity in mouse Hb9 interneurons. J Neurophysiol 98:2370-2381.
38. Wilson JM, Dombeck DA, Díaz-Ríos M, Harris-Warrick RM, Brownstone RM (2007b) Two-photon calcium imaging of network activity in XFP-expressing neurons in the mouse. J Neurophysiol 97:3118-3125. (Pubitemid 46557738)
39. Wilson JM, Cowan AI, Brownstone RM (2008) Hb9 interneurons: reply to Ziskind-Conhaim and Hinckley. J Neurophysiol 99:1047-1049.
40. Zar JH (1996) Biostatistical analysis, Ed 3. Upper Saddle River, NJ: Prentice Hall.
41. Zhong G, Masino MA, Harris-Warrick RM (2007) Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord. J Neurosci 27:4507-4518. (Pubitemid 46663577)
42. Zipfel WR, Williams RM, Webb WW (2003) Nonlinear magic: multiphoton microscopy in the biosciences. Nat Biotechnol 21:1369-1377.
43. Ziskind-Conhaim L, Hinckley CA (2008a) Hb9 versus type 2 interneurons. J Neurophysiol 99:1044-1046; author reply 1047-1049.
44. Ziskind-Conhaim L, Wu L, Wiesner EP (2008b) Persistent sodium current contributes to induced voltage oscillations in locomotor-related Hb9 interneurons in the mouse spinal cord. J Neurophysiol 100:2254-2264.