Evaluation of a novel Arg-Gly-Asp-conjugated α-melanocyte stimulating hormone hybrid peptide for potential melanoma therapy

Bioconjugate Chemistry

Volumn 20, Issue 8, 2009, Pages 1634-1642

  Yang, Jianquan ^a   Guo, Haixun ^a   Gallazzi, Fabio ^d   Berwick, Marianne ^b,c   Padilla, R Steven ^b,c   Miao, Yubin ^a,b,c  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CELLS; CYTOTOXICITY; DERMATOLOGY; MAMMALS; PARTICLE BEAMS; PEPTIDES; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TUMORS;

ARG GLY ASPS; BINDING AFFINITIES; CYTOTOXIC EFFECTS; HYBRID PEPTIDES; MELANOCORTINS; MELANOMA CELLS; PHARMACOKINETIC PROPERTIES; POST INJECTION; RECEPTOR BINDING; RGD MOTIF;

ONCOLOGY;

ALPHA INTERMEDIN; ARGININE; ARGINYLGLYCYLASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID LYSINE (ARGININE 11) TECHNETIUM 99M; CYSTINE; MELANOCORTIN 1 RECEPTOR; PHENYLALANINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CELL SURVIVAL; CLONOGENIC ASSAY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; INCUBATION TIME; INTERNALIZATION; KIDNEY; KIDNEY TUBULE ABSORPTION; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; RADIOACTIVITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; URINARY TRACT;

ANIMALIA; MUS;

ALPHA-MSH; ANIMALS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; FEMALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNETIUM; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 70349139674     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9001954     Document Type: Article

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