Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 9, 2009, Pages 3720-3725

  Ginsberg, Ann M ^a   Laurenzi, Martino W ^a   Rouse, Doris J ^b   Whitney, Karl D ^b   Spigelman, Melvin K ^a  

^a GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT   (United States)

^b RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; PLACEBO;

ADULT; AREA UNDER THE CURVE; ARTICLE; BACKACHE; CREATININE BLOOD LEVEL; DIARRHEA; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FLATULENCE; HEADACHE; HUMAN; HUMAN EXPERIMENT; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NAUSEA; NORMAL HUMAN; PRIORITY JOURNAL; SIDE EFFECT; STOMACH DISCOMFORT; TIME TO MAXIMUM PLASMA CONCENTRATION; VITAL SIGN; VOMITING;

ADULT; ANTITUBERCULAR AGENTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; NITROIMIDAZOLES; YOUNG ADULT;

EID: 70349105953     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00106-09     Document Type: Article

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