Flow perfusion culture of human fetal bone cells in large β-tricalcium phosphate scaffold with controlled architecture

Journal of Biomedical Materials Research - Part A

Volumn 91, Issue 1, 2009, Pages 102-113

  Wang, Lin ^a   Hu, Yun Yu ^a   Wang, Zhen ^a   Li, Xiang ^b   Li, Di Chen ^b   Lu, Bing Heng ^b   Xu, Song Feng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Architecture; Bioreactor; Flow perfusion; Human fetal cells; Scaffolds

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BONE CELLS; BONE GRAFT; BONE TISSUE ENGINEERING; CELL BEHAVIORS; CELL VIABILITY; CHANNEL ARCHITECTURE; CONTROLLED ARCHITECTURE; FLOW PERFUSION; FLUID FLOW; GLUCOSE CONSUMPTION; HUMAN FETAL CELLS; MATRIX; OSTEOPONTIN; PERFUSION BIOREACTOR; PERFUSION CULTURES; POROUS SCAFFOLD; POTENTIAL TOOL; PROLIFERATION OF OSTEOBLASTIC CELLS; STATIC CULTURE; THREE-DIMENSIONAL ENVIRONMENT; TRI-CALCIUM PHOSPHATES; UNSOLVED PROBLEMS;

BIOMATERIALS; BIOREACTORS; BONE; CELL CULTURE; CELL MEMBRANES; FLOW OF FLUIDS; GLUCOSE; GRAFTS; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING;

SCAFFOLDS;

ALKALINE PHOSPHATASE; CALCIUM PHOSPHATE; GLUCOSE; OSTEOPONTIN; TISSUE SCAFFOLD;

ARTICLE; BIOREACTOR; BONE CELL; BONE GRAFT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FETUS CELL; HISTOLOGY; HUMAN; HUMAN CELL; SCANNING ELECTRON MICROSCOPY;

ABORTED FETUS; ALKALINE PHOSPHATASE; CALCIUM PHOSPHATES; CELL SURVIVAL; CELLS, CULTURED; EQUIPMENT DESIGN; GLUCOSE; HUMANS; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; OSTEOPONTIN; PERFUSION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 70349094123     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32189     Document Type: Article

References (38)

1. Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 1997;64:295-312. (Pubitemid 27065443)
2. Petite H, Viateau V, Bensaid W, Meunier A, de Pollak C, Bourguignon M, Oudina K, Sedel L, Guillemin G. Tissue-engineered bone regeneration. Nat Biotechnol 2000;18:959-963.
3. Kruyt MC, Dhert WJ, Oner FC, van Blitterswijk CA, Verbout AJ, de Bruijn JD. Analysis of ectopic and orthotopic bone formation in cell-based tissue-engineered constructs in goats. Biomaterials 2007;28:1798-1805.
4. Meinel L, Betz O, Fajardo R, Hofmann S, Nazarian A, Cory E, Hilbe M, McCool J, Langer R, Vunjak-Novakovic G, Merkle HP, Rechenberg B, Kaplan DL, Kirker-Head C. Silk based biomaterials to heal critical sized femur defects. Bone 2006;39:922-931. (Pubitemid 44311718)
5. D'Ippolito G, Schiller PC, Ricordi C, Roos BA, Howard GA. Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow. J Bone Miner Res 1999;14:1115-1122. (Pubitemid 29314054)
6. Schecroun N, Delloye C. Bone-like nodules formed by human bone marrow stromal cells: Comparative study and characterization. Bone 2003;32:252-260. (Pubitemid 36349528)
7. Montjovent MO, Burri N, Mark S, Federici E, Scaletta C, Zambelli PY, Hohlfeld P, Leyvraz PF, Applegate LL, Pioletti DP. Fetal bone cells for tissue engineering. Bone 2004;35:1323-1333. (Pubitemid 40260395)
8. Ishaug-Riley SL, Crane-Kruger GM, Yaszemski MJ, Mikos AG. Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 1998;19:1405-1412.
9. Holy CE, Shoichet MS, Davies JE. Engineering three-dimensional bone tissue in vitro using biodegradable scaffolds: Investigating initial cell-seeding density and culture period. J Biomed Mater Res 2000;51:376-382.
10. Bancroft GN, Sikavitsas VI, van den Dolder J, Sheffield TL, Ambrose CG, Jansen JA, Mikos AG. Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci USA 2002;99:12600-12605.
11. Sikavitsas VI, Bancroft GN, Lemoine JJ, Liebschner MA, Dauner M, Mikos AG. Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable non-woven fiber mesh scaffolds. Ann Biomed Eng 2005;33:63-70. (Pubitemid 40496060)
12. Gomes ME, Sikavitsas VI, Behravesh E, Reis RL, Mikos AG. Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A 2003;67:87-95. (Pubitemid 37517158)
13. Holtorf HL, Sheffield TL, Ambrose CG, Jansen JA, Mikos AG. Flow perfusion culture of marrow stromal cells seeded on porous biphasic calcium phosphate ceramics. Ann Biomed Eng 2005;33:1238-1248.
14. Sikavitsas VI, Bancroft GN, Holtorf HL, Jansen JA, Mikos AG. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci USA 2003;100:14683-14688
15. van den Dolder J, Bancroft GN, Sikavitsas VI, Spauwen PH, Jansen JA, Mikos AG. Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A 2003;64:235-241.
16. Fassina L, Visai L, Asti L, Benazzo F, Speziale P, Tanzi MC, Magenes G. Calcified matrix production by SAOS-2 cells inside a polyurethane porous scaffold, using a perfusion bioreactor. Tissue Eng 2005;11:685-700. (Pubitemid 40960773)
17. Xie Y, Hardouin P, Zhu Z, Tang T, Dai K, Lu J. Three-dimensional flow perfusion culture system for stem cell proliferation inside the critical-size β-tricalcium phosphate scaffold. Tissue Eng 2006;12:3535-3543. (Pubitemid 46037175)
18. Li X, Li D, Lu B, Tang Y, Wang L, Wang Z. Design and fabrication of CAP scaffolds by indirect solid free form fabrication. Rapid Prototyping J 2005;11:312-318.
19. Chu TM, Halloran JW, Hollister SJ, Feinberg SE. Hydroxyapatite implants with designed internal architecture. J Mater Sci: Mater Med 2001;12:471-478.
20. Robey PG, Termine JD. Human bone cells in vitro. Calcif Tissue Int 1985;37:453-460.
21. Ciapetti G, Cenni E, Pratelli L, Pizzoferrato A. In vitro evaluation of cell/biomaterial interaction by MTT assay. Biomaterials 1993;14:359-364.
22. Ishaug SL, Crane GM, Miller MJ, Yasko AW, Yaszemski MJ, Mikos AG. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J Biomed Mater Res 1997;36:17-28.
23. Holtorf HL, Jansen JA, Mikos AG. Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. J Biomed Mater Res A 2005;72:326-334.
24. Sikavitsas VI, Bancroft GN, Mikos AG. Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. J Biomed Mater Res 2002;62:136-148.
25. Goldstein AS, Juarez TM, Helmke CD, Gustin MC, Mikos AG. Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds. Biomaterials 2001;22:1279-1288.
26. Wang Y, Uemura T, Dong J, Kojima H, Tanaka J, Tateishi T. Application of perfusion culture system improves in vitro and in vivo osteogenesis of bone marrow-derived osteoblastic cells in porous ceramic materials. Tissue Eng 2003;9:1205-1214. (Pubitemid 37467668)
27. Bancroft GN, Sikavitsas VI, Mikos AG. Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng 2003;9:549-554.
28. Cartmell SH, Porter BD, Garcia AJ, Guldberg RE. Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs in vitro. Tissue Eng 2003;9:1197-1203.
29. Hosseinkhani H, Hosseinkhani M, Tian F, Kobayashi H, Tabata Y. Ectopic bone formation in collagen sponge self-assembled peptide-amphiphile nanofibers hybrid scaffold in a perfusion culture bioreactor. Biomaterials 2006;27:5089-5098. (Pubitemid 43928128)
30. Lian JB, Stein GS. Concepts of osteoblast growth and differentiation: Basis for modulation of bone cell development and tissue formation. Crit Rev Oral Biol Med 1992;3:269-305.
31. Aubin JE. Osteogenic cell differentiation. In: Davies JE, editor. Bone Engineering. Toronto: Em Squared; 2000. pp 19-29.
32. Leskela HV, Risteli J, Niskanen S, Koivunen J, Ivaska KK, Lehenkari P. Osteoblast recruitment from stem cells does not decrease by age at late adulthood. Biochem Biophys Res Commun 2003;311:1008-1013. (Pubitemid 37393419)
33. Montjovent MO, Mathieu L, Hinz B, Applegate LL, Bourban PE, Zambelli PY, Månson JA, Pioletti DP. Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells. Tissue Eng 2005;11:1640-1649. (Pubitemid 43120175)
34. Akay G, Birch MA, Bokhari MA. Microcellular polyHIPE polymer supports osteoblast growth and bone formation in vitro. Biomaterials 2004;25:3991-4000. (Pubitemid 38388565)
35. Takahashi Y, Tabata Y. Effect of the fiber diameter and porosity of non-woven PET fabrics on the osteogenic differentiation of mesenchymal stem cells. J Biomater Sci Polym Ed 2004;15:41-57. (Pubitemid 38239670)
36. Okamoto M, Dohi Y, Ohgushi H, Shimaoka H, Ikeuchi M, Matsushima A, Yonemasu K, Hosoi H. Influence of the porosity of hydroxyapatite ceramics on in vitro and in vivo bone formation by cultured rat bone marrow stromal cells. J Mater Sci: Mater Med 2006;17:327-336. (Pubitemid 43042226)
37. Gomes ME, Holtorf HL, Reis RL, Mikos AG. Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flowperfusion bioreactor. Tissue Eng 2006;12:801-809.
38. Holtorf HL, Datta N, Jansen JA, Mikos AG. Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor. J Biomed Mater Res A 2005;74:171-180. (Pubitemid 40995531)