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Volumn 4, Issue 9, 2009, Pages 1313-1327

Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; GLUCOSE;

EID: 70249117816     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2009.117     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 0031906044 scopus 로고    scopus 로고
    • Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies in vitro in animals and in humans
    • Macallan, D.C. et al. Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies in vitro in animals and in humans. Proc. Natl. Acad. Sci. USA 95, 708-713 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 708-713
    • Macallan, D.C.1
  • 2
    • 0033214567 scopus 로고    scopus 로고
    • Measurement of T-cell kinetics: Recent methodologic advances
    • Hellerstein, M.K. Measurement of T-cell kinetics: Recent methodologic advances. Immunol. Today 20, 438-441 (1999).
    • (1999) Immunol. Today , vol.20 , pp. 438-441
    • Hellerstein, M.K.1
  • 4
    • 0037180449 scopus 로고    scopus 로고
    • 2O labeling of the deoxyribose moiety of DNA
    • 2O labeling of the deoxyribose moiety of DNA. Proc. Natl. Acad. Sci. USA 99, 15345-15350 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15345-15350
    • Neese, R.A.1
  • 5
    • 0042476384 scopus 로고    scopus 로고
    • Measurement and modeling of human T cell kinetics
    • Macallan, D.C. et al. Measurement and modeling of human T cell kinetics. Eur. J. Immunol. 33, 2316-2326 (2003).
    • (2003) Eur. J. Immunol , vol.33 , pp. 2316-2326
    • Macallan, D.C.1
  • 7
    • 0028267677 scopus 로고
    • Turnover of naive- and memory-phenotype T cells
    • Tough, D.F. & Sprent, J. Turnover of naive- and memory-phenotype T cells. J. Exp. Med. 179, 1127-1135 (1994).
    • (1994) J. Exp. Med , vol.179 , pp. 1127-1135
    • Tough, D.F.1    Sprent, J.2
  • 8
    • 0035905463 scopus 로고    scopus 로고
    • Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV
    • Kovacs, J.A. et al. Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV. J. Exp. Med. 194, 1731-1741 (2001).
    • (2001) J. Exp. Med , vol.194 , pp. 1731-1741
    • Kovacs, J.A.1
  • 9
    • 0022496835 scopus 로고
    • Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67
    • Schwarting, R., Gerdes, J., Niehus, J., Jaeschke, L. & Stein, H. Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67. J. Immunol. Methods 90, 65-70 (1986).
    • (1986) J. Immunol. Methods , vol.90 , pp. 65-70
    • Schwarting, R.1    Gerdes, J.2    Niehus, J.3    Jaeschke, L.4    Stein, H.5
  • 10
    • 37649021448 scopus 로고    scopus 로고
    • Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester
    • Quah, B.J., Warren, H.S. & Parish, C.R. Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nat. Protoc. 2, 2049-2056 (2007).
    • (2007) Nat. Protoc , vol.2 , pp. 2049-2056
    • Quah, B.J.1    Warren, H.S.2    Parish, C.R.3
  • 11
    • 37649019847 scopus 로고    scopus 로고
    • Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data
    • Hawkins, E.D. et al. Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nat. Protoc. 2 2057-2067 (2007).
    • (2007) Nat. Protoc , vol.2 , pp. 2057-2067
    • Hawkins, E.D.1
  • 12
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons, A.B. Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J. Immunol. Methods 243, 147-154 (2000).
    • (2000) J. Immunol. Methods , vol.243 , pp. 147-154
    • Lyons, A.B.1
  • 13
    • 0026445567 scopus 로고
    • Lifespan of human lymphocyte subsets defined by CD45 isoforms
    • Michie, C.A., McLean, A., Alcock, C. & Beverley, P.C. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 360, 264-265 (1992).
    • (1992) Nature , vol.360 , pp. 264-265
    • Michie, C.A.1    McLean, A.2    Alcock, C.3    Beverley, P.C.4
  • 14
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho, D.D. et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123-126 (1995).
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1
  • 15
    • 33646368240 scopus 로고    scopus 로고
    • Calculation of substrate kinetics: Single pool model
    • eds. Wolfe, R.R. & Chinkes, D.L, John Wiley & Sons, Hoboken, New Jersey
    • Wolfe, R.R. & Chinkes, D.L. Calculation of substrate kinetics: Single pool model. in Isotope Tracers in Metabolic Research (eds. Wolfe, R.R. & Chinkes, D.L.) 21-50 (John Wiley & Sons, Hoboken, New Jersey, 2005).
    • (2005) Isotope Tracers in Metabolic Research , pp. 21-50
    • Wolfe, R.R.1    Chinkes, D.L.2
  • 16
    • 50949130685 scopus 로고    scopus 로고
    • Central memory CD8(+) T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression
    • Ladell, K. et al. Central memory CD8(+) T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression. J. Immunol. 180, 7907-7918 (2008).
    • (2008) J. Immunol , vol.180 , pp. 7907-7918
    • Ladell, K.1
  • 17
    • 43149105163 scopus 로고    scopus 로고
    • Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool
    • Vrisekoop, N. et al. Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool. Proc. Natl. Acad. Sci. USA 105, 6115-6120 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 6115-6120
    • Vrisekoop, N.1
  • 18
    • 33748296240 scopus 로고    scopus 로고
    • Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo
    • Vukmanovic-Stejic, M. et al. Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo. J. Clin. Invest. 116, 2423-2433 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 2423-2433
    • Vukmanovic-Stejic, M.1
  • 19
    • 0242319539 scopus 로고    scopus 로고
    • Rapid turnover of T cells in acute infectious mononucleosis
    • Macallan, D.C. et al. Rapid turnover of T cells in acute infectious mononucleosis. Eur. J. Immunol. 33, 2655-2665 (2003).
    • (2003) Eur. J. Immunol , vol.33 , pp. 2655-2665
    • Macallan, D.C.1
  • 20
    • 3242751959 scopus 로고    scopus 로고
    • Rapid turnover of effector-memory CD4(+) T cells in healthy humans
    • Macallan, D.C. et al. Rapid turnover of effector-memory CD4(+) T cells in healthy humans. J. Exp. Med. 200, 255-260 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 255-260
    • Macallan, D.C.1
  • 21
    • 3242794119 scopus 로고    scopus 로고
    • Direct measurement of T cell subset kinetics in vivo in elderly men and women
    • Wallace, D.L. et al. Direct measurement of T cell subset kinetics in vivo in elderly men and women. J. Immunol. 173, 1787-1794 (2004).
    • (2004) J. Immunol , vol.173 , pp. 1787-1794
    • Wallace, D.L.1
  • 22
    • 20944438218 scopus 로고    scopus 로고
    • B cell kinetics in humans: Rapid turnover of peripheral blood memory cells
    • Macallan, D.C. et al. B cell kinetics in humans: Rapid turnover of peripheral blood memory cells. Blood 105, 3633-3640 (2005).
    • (2005) Blood , vol.105 , pp. 3633-3640
    • Macallan, D.C.1
  • 23
    • 52649102416 scopus 로고    scopus 로고
    • Reduction of B cell turnover in chronic lymphocytic leukaemia
    • Defoiche, J. et al. Reduction of B cell turnover in chronic lymphocytic leukaemia. Br. J. Haematol. 143, 240-247 (2008).
    • (2008) Br. J. Haematol , vol.143 , pp. 240-247
    • Defoiche, J.1
  • 24
    • 17444379333 scopus 로고    scopus 로고
    • Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans
    • Hellerstein, M. et al. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat. Med. 5 83-89 (1999).
    • (1999) Nat. Med , vol.5 , pp. 83-89
    • Hellerstein, M.1
  • 25
    • 0142186676 scopus 로고    scopus 로고
    • Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection
    • Hellerstein, M.K. et al. Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection. J. Clin. Invest. 112, 956-966 (2003).
    • (2003) J. Clin. Invest , vol.112 , pp. 956-966
    • Hellerstein, M.K.1
  • 26
    • 0034060982 scopus 로고    scopus 로고
    • Factors influencing T-cell turnover in HIV-1-seropositive patients
    • McCune, J.M. et al. Factors influencing T-cell turnover in HIV-1-seropositive patients. J. Clin. Invest. 105, R1-R8 (2000).
    • (2000) J. Clin. Invest , vol.105
    • McCune, J.M.1
  • 27
    • 23644439060 scopus 로고    scopus 로고
    • Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients
    • Kovacs, J.A. et al. Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients. J. Clin. Invest. 115, 2139-2148 (2005).
    • (2005) J. Clin. Invest , vol.115 , pp. 2139-2148
    • Kovacs, J.A.1
  • 28
    • 51749108013 scopus 로고    scopus 로고
    • CD4 T cell survival after intermittent Interleukin-2 therapy is predictive of an Increase in the CD4 T cell count of HIV-infected patients
    • Read, S.W. et al. CD4 T cell survival after intermittent Interleukin-2 therapy is predictive of an Increase in the CD4 T cell count of HIV-infected patients. J. Infect. Dis. 198, 843-850 (2008).
    • (2008) J. Infect. Dis , vol.198 , pp. 843-850
    • Read, S.W.1
  • 29
    • 21744443845 scopus 로고    scopus 로고
    • Measuring lymphocyte kinetics in tropical field settings
    • Ghattas, H. et al. Measuring lymphocyte kinetics in tropical field settings. Trans. R. Soc. Trop. Med. Hyg. 99, 675-685 (2005).
    • (2005) Trans. R. Soc. Trop. Med. Hyg , vol.99 , pp. 675-685
    • Ghattas, H.1
  • 30
    • 33846855790 scopus 로고    scopus 로고
    • Long-term effects of perinatal nutrition on T lymphocyte kinetics in young Gambian men
    • Ghattas, H. et al. Long-term effects of perinatal nutrition on T lymphocyte kinetics in young Gambian men. Am. J. Clin. Nutr. 85 480-487 (2007).
    • (2007) Am. J. Clin. Nutr , vol.85 , pp. 480-487
    • Ghattas, H.1
  • 31
    • 0023925454 scopus 로고
    • Interactions between deoxyribonucleotide and DNA synthesis
    • Reichard, P. Interactions between deoxyribonucleotide and DNA synthesis. Annu. Rev. Biochem. 57, 349-374 (1988).
    • (1988) Annu. Rev. Biochem , vol.57 , pp. 349-374
    • Reichard, P.1
  • 32
    • 0021050706 scopus 로고
    • Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism
    • Cohen, A., Barankiewicz, J., Lederman, H.M. & Gelfand, E.W. Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism. J. Biol. Chem. 258, 12334-12340 (1983).
    • (1983) J. Biol. Chem , vol.258 , pp. 12334-12340
    • Cohen, A.1    Barankiewicz, J.2    Lederman, H.M.3    Gelfand, E.W.4
  • 33
    • 85182974073 scopus 로고    scopus 로고
    • General immunologic evaluation of patients with human immunodeficiency virus infection
    • eds. Detrick, B, Hamilton, R.G. & Folds, J.D, ASM Press, Washington DC
    • Stevens, R.A. et al. General immunologic evaluation of patients with human immunodeficiency virus infection. in Manual of Molecular and Clinical Laboratory Immunology (eds. Detrick, B., Hamilton, R.G. & Folds, J.D.) 848-861 (ASM Press, Washington DC, 2006).
    • (2006) Manual of Molecular and Clinical Laboratory Immunology , pp. 848-861
    • Stevens, R.A.1
  • 34
    • 3142750530 scopus 로고    scopus 로고
    • Activation, differentiation, and migration of naive virus-specific CD8+ T cells during pulmonary influenza virus infection
    • Lawrence, C.W. & Braciale, T.J. Activation, differentiation, and migration of naive virus-specific CD8+ T cells during pulmonary influenza virus infection. J. Immunol. 173, 1209-1218 (2004).
    • (2004) J. Immunol , vol.173 , pp. 1209-1218
    • Lawrence, C.W.1    Braciale, T.J.2
  • 35
    • 34548413609 scopus 로고    scopus 로고
    • Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection
    • Okoye, A. et al. Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. J. Exp. Med. 204, 2171-2185 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 2171-2185
    • Okoye, A.1
  • 36
    • 4243299732 scopus 로고    scopus 로고
    • Measuring the diaspora for virus-specific CD8+ T cells
    • Marshall, D.R. et al. Measuring the diaspora for virus-specific CD8+ T cells. Proc. Natl. Acad. Sci. USA 98, 6313-6318 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6313-6318
    • Marshall, D.R.1
  • 37
    • 34250351311 scopus 로고    scopus 로고
    • Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation
    • Agrewala, J.N. et al. Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J. Biol. Chem. 282, 6106-6115 (2007).
    • (2007) J. Biol. Chem , vol.282 , pp. 6106-6115
    • Agrewala, J.N.1
  • 38
    • 34250877389 scopus 로고    scopus 로고
    • Cutting edge: Migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells
    • Marzo, A.L., Yagita, H. & Lefrancois, L. Cutting edge: Migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells. J. Immunol. 179, 36-40 (2007).
    • (2007) J. Immunol , vol.179 , pp. 36-40
    • Marzo, A.L.1    Yagita, H.2    Lefrancois, L.3
  • 39
    • 0142092623 scopus 로고    scopus 로고
    • Optimized lymphocyte isolation methods for analysis of chemokine receptor expression
    • Berhanu, D., Mortari, F., De Rosa, S.C. & Roederer, M. Optimized lymphocyte isolation methods for analysis of chemokine receptor expression. J. Immunol. Methods 279, 199-207 (2003).
    • (2003) J. Immunol. Methods , vol.279 , pp. 199-207
    • Berhanu, D.1    Mortari, F.2    De Rosa, S.C.3    Roederer, M.4
  • 40
    • 0025977687 scopus 로고
    • Humans with OKT4-epitope deficiency have a single nucleotide base change in the CD4 gene, resulting in substitution of TRP240 for ARG240
    • Hodge, T.W., Sasso, D.R. & McDougal, J.S. Humans with OKT4-epitope deficiency have a single nucleotide base change in the CD4 gene, resulting in substitution of TRP240 for ARG240. Hum. Immunol. 30, 99-104 (1991).
    • (1991) Hum. Immunol , vol.30 , pp. 99-104
    • Hodge, T.W.1    Sasso, D.R.2    McDougal, J.S.3
  • 41
    • 33644557158 scopus 로고    scopus 로고
    • Altered CD45 expression and disease
    • Tchilian, E.Z. & Beverley, P.C. Altered CD45 expression and disease. Trends Immunol. 27, 146-153 (2006).
    • (2006) Trends Immunol , vol.27 , pp. 146-153
    • Tchilian, E.Z.1    Beverley, P.C.2
  • 42
    • 0035892726 scopus 로고    scopus 로고
    • Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation
    • Neese, R.A. et al. Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation. Anal. Biochem. 298, 189-195 (2001).
    • (2001) Anal. Biochem , vol.298 , pp. 189-195
    • Neese, R.A.1
  • 43
    • 0344737998 scopus 로고    scopus 로고
    • 2]-glucose metabolic probe in T-cell genomic DNA
    • 2]-glucose metabolic probe in T-cell genomic DNA. Anal. Chem. 75, 6517-6522 (2003).
    • (2003) Anal. Chem , vol.75 , pp. 6517-6522
    • Fox, S.D.1
  • 44
    • 34249950287 scopus 로고    scopus 로고
    • In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection
    • Asquith, B. et al. In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection. Proc. Natl. Acad. Sci. USA 104, 8035-8040 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8035-8040
    • Asquith, B.1
  • 45
    • 33947225091 scopus 로고    scopus 로고
    • Quantification of T-cell dynamics: From telomeres to DNA labeling
    • Borghans, J.A. & De Boer, R.J. Quantification of T-cell dynamics: From telomeres to DNA labeling. Immunol. Rev. 216, 35-47 (2007).
    • (2007) Immunol. Rev , vol.216 , pp. 35-47
    • Borghans, J.A.1    De Boer, R.J.2
  • 46
    • 0036278287 scopus 로고    scopus 로고
    • HIV tropism and CD4+ T-cell depletion
    • Hellerstein, M. HIV tropism and CD4+ T-cell depletion. Nat. Med. 8, 537-538 (2002).
    • (2002) Nat. Med , vol.8 , pp. 537-538
    • Hellerstein, M.1
  • 47
    • 0037180499 scopus 로고    scopus 로고
    • In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted?
    • Ribeiro, R.M., Mohri, H., Ho, D.D. & Perelson, A.S. In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted? Proc. Natl. Acad. Sci. USA 99, 15572-15577 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15572-15577
    • Ribeiro, R.M.1    Mohri, H.2    Ho, D.D.3    Perelson, A.S.4
  • 48
    • 0035169609 scopus 로고    scopus 로고
    • Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
    • Mohri, H. et al. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J. Exp. Med. 194, 1277-1287 (2001).
    • (2001) J. Exp. Med , vol.194 , pp. 1277-1287
    • Mohri, H.1
  • 49
    • 33644748244 scopus 로고    scopus 로고
    • Naive T-cell dynamics in human immunodeficiency virus type 1 infection: Effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion
    • Di, M.M. et al. Naive T-cell dynamics in human immunodeficiency virus type 1 infection: Effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion. J. Virol. 80, 2665-2674 (2006).
    • (2006) J. Virol , vol.80 , pp. 2665-2674
    • Di, M.M.1
  • 50
    • 34247538298 scopus 로고    scopus 로고
    • In vivo kinetics of human natural killer cells: The effects of ageing and acute and chronic viral infection
    • Zhang, Y. et al. In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection. Immunology 121, 258-265 (2007).
    • (2007) Immunology , vol.121 , pp. 258-265
    • Zhang, Y.1
  • 51
    • 0036698287 scopus 로고    scopus 로고
    • CD4 lymphocytes in the blood of HIV(+) individuals migrate rapidly to lymph nodes and bone marrow: Support for homing theory of CD4 cell depletion
    • Chen, J.J. et al. CD4 lymphocytes in the blood of HIV(+) individuals migrate rapidly to lymph nodes and bone marrow: Support for homing theory of CD4 cell depletion. J. Leukoc. Biol. 72, 271-278 (2002).
    • (2002) J. Leukoc. Biol , vol.72 , pp. 271-278
    • Chen, J.J.1


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