hGH release from directly compressed hGH-PLGA biodegradable implantable tablets: Influence of physicomechanical factors

European Polymer Journal

Volumn 45, Issue 10, 2009, Pages 2830-2838

  Santoveña, Ana ^a   Alvarez Lorenzo, Carmen ^b   Llabrés, Matias ^a   Concheiro, Angel ^b   Fariña, Jose B ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Human growth hormone; Implantable tablet; Poly(d,l lactide co glycolide); Porosity; Rheometry

Indexed keywords

AQUEOUS MEDIUM; COMPRESSION FORCE; DEGRADATION RATE; DIRECT COMPRESSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; GAINING INSIGHTS; HUMAN GROWTH HORMONE; IMPLANTABLE TABLET; PHOSPHATE BUFFERS; PHYSICOMECHANICAL; PHYSICOMECHANICAL PROPERTIES; POLY(D,L-LACTIDE-CO-GLYCOLIDE); POLYMER DEGRADATION; RELEASE RATE; RHEOMETRY; RUBBER TRANSITION TEMPERATURE; VISCOELASTIC PROPERTIES; WATER PENETRATION; WATER UPTAKE;

BIODEGRADABLE POLYMERS; CONTROLLED DRUG DELIVERY; ELASTIC MODULI; GLASS TRANSITION; MOLECULAR WEIGHT; ORGANIC POLYMERS; POLYMER BLENDS; POROSITY; RHEOMETERS;

DEGRADATION;

EID: 70249115752     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2009.07.007     Document Type: Article

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