Transcriptional repression of matrix metalloproteinase gene expression by the orphan nuclear receptor NURR1 in cartilage

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 9492-9504

  Mix, Kimberlee S ^a   Attur, Mukundan G ^b   Al Mussawir, Hayf ^b   Abramson, Steven B ^b   Brinckerhoff, Constance E ^c   Murphy, Evelyn P ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b NYU HOSPITAL FOR JOINT DISEASES   (United States)

^c DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARTILAGE; DISEASES; ENZYMES; GROWTH KINETICS; JOINTS (ANATOMY); MOLECULAR DYNAMICS;

INFLAMMATORY JOINT DISEASE; MATRIX METALLOPROTEINASE GENE EXPRESSION; TRANSCRIPTIONAL REPRESSION;

GENE EXPRESSION;

COLLAGENASE 3; CYCLOOXYGENASE 2; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; NUCLEAR RECEPTOR RELATED FACTOR 1; PROSTAGLANDIN E2; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR ETS 1; DNA BINDING PROTEIN; NURR1 NUCLEAR RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; EMBRYO; ENZYME BINDING; ENZYME BLOOD LEVEL; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE BINDING SITE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR INTRINSIC ACTIVITY; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; ANIMAL; ARTICULAR CARTILAGE; BIOSYNTHESIS; CELL CULTURE; DOWN REGULATION; DRUG ANTAGONISM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HOMEOSTASIS; INFLAMMATION; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

AGED; ANIMALS; CARTILAGE, ARTICULAR; CELL LINE, TUMOR; CELLS, CULTURED; DNA-BINDING PROTEINS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEOSTASIS; HUMANS; INFLAMMATION; MATRIX METALLOPROTEINASES; MICE; MIDDLE AGED; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 34248166702     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608327200     Document Type: Article

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