Antinociceptive property of Trigonella foenum graecum (Fenugreek seeds) in high fat diet-fed/low dose streptozotocin induced diabetic neuropathy in rats

Pharmacologyonline

Volumn 2, Issue , 2009, Pages 24-36

  Nanjundan, Prem Kumar ^a   Arunachalam, Annamalai ^b   Thakur, Ram Sharnagat ^a  

^a KRUPANIDHI COLLEGE OF PHARMACY   (India)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidant; Diabetic neuropathy; Nociception; Oxidative stress; Trigonella foenum graecum

Indexed keywords

GLUCOSE; QUERCETIN; TRIGONELLA FOENUM GRAECUM EXTRACT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFICACY; DRUG MEGADOSE; FENUGREEK; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HYPERALGESIA; LIPID DIET; LOW DRUG DOSE; MALE; NERVE FIBER DEGENERATION; NOCICEPTIVE STIMULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PLANT SEED; RAT; SINGLE DRUG DOSE; STIMULUS RESPONSE; STREPTOZOCIN DIABETES; TAIL FLICK TEST; THERMAL STIMULATION;

EID: 70149124731     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Cameron NE & Cotter MA. Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes. Diabetes Res Clin Pract, 1999;45: 137.
2. Januszewski AS, Alderson NI, Metz TO, Thorpe SR & Baynes JW. Role of lipids in chemical modification of proteins and development of complications of diabetes. Biochem Soc Trans 2003; 31:1413.
3. James JL, Michael FJ & Elizabeth AK. An adenosine inhibitor attenuates tactile allodynia in rats model of diabetic neuropathy. Eur J Pharmacol 1999; 364:141.
4. Courteix C, Bardin M, Chantelauze C, Lavarenne J & Eschalier A. Study of the sensitivity of the diabetic-induced pain model in rats to range of analgesics. Pain 1994; 57:153.
5. Gul H, Yildiz O, Dogrul A, Yesilyurt O & Isimer A, The interaction between IL-1beta and morphine: possible mechanisms of the deficiency of the morphine-induced analgesia in diabetic mice. Pain 2000; 15: 39.
6. Clark J M & Lee DA. Prevention and treatment of the complications of diabetes mellitus. N Engl J Med 1995; 332:1210.
7. Freshwater JD, Svensson CI, Malmberg AB and Calcutt NA. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes 2002;51:2249-2255.
8. Malmberg AB and Yaksh TL Cyclooxygenase Inhibition and the Spinal Release of Prostaglandin E, and Amino Acids Evoked by Paw Formalin Injection: A Microdialysis Study in Unanesthetized Rats. J Neuroscience 1995; 15(4): 2768-2776.
9. Alarcon-Aguilara FJ, Roman-Ramos R, Perez-Gutierrez S. Study of the anti-hyperglycemic effect of plants used as anti-diabetics. J Ethnopharmacol 1998;61:101-10.
10. Pari L, Umamaheswari J. Antihyperglycaemic activity of Musa sapientum flowers: effect on lipid peroxidation in alloxan diabetic rats. Phytother Res 2000;14:1-3.
11. Vats V, Grover JK, Rathi SS. Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats. J Ethnopharmacol 2002;79:95-100.
12. Thakur AM, Sarvaiya JG, Bhavsar SK. Studies on anti-inflammatory activities of Trigonella in rats. Update Ayurveda 1994:75.Bombay:India.
13. Puri D. Therapeutic potential of fenugreek. Indian J Physiol Pharmacol 1998;42:423-4.
14. Mishkinsky J, Joseph B, Sulman F. Hypoglycemic effect of trigonelline. Lancet 1967;1:1311-2.
15. Sharma RD. Effect of fenugreek seeds and leaves blood glucose and serum insulin responses in human subjects. Nurt Res 1986;6:1353-64.
16. Preet A, Gupta BL, Siddiqui MR, Yadava PK, Baquer NZ. Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella - a promising antidiabetic agent. Mol Cell Biochem. 2005;278(1-2):21-31
17. Shang M, Cais Han J, Li J. Studies on flavonoids from fenugreek (Trigonella foenum graecum L.). Zhongguo Zhong Yao Za Zhi 1999; 23:614-39.
18. Anjaneyulu M, Chopra K, Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain, Prog Neuro-Psychopharmacol Biol Psych 2003; 27: 1001-1005.
19. Bronner C and Landry Y. Kinetics of the inhibitory effect of flavonoids on histamine secretion from mast cells. Agents Actions 1985;16:147-151.
20. De-Whalley C, Rankin SM, Houct JRS, Jessup W and Leake DS. Flavonoids inhibit the oxidative modification of low-density lipoproteins by macrophages. Biochem Pharmacol 1990;39:1743-1750.
21. Sleder J, Chen YDI, Culli MD and Reaven GM. Hyperinsulimenia in fructose induced hypertriglycerdemia in the rat. Metabolism 1981;29:303-305.
22. Srinivasan K, Viswanad B, Asrat L, Kaul CL and Ramarao P. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening. Pharmacol Res 2005;52:313-320.
23. Khosla P, Gupta DD and Nagpal RK. Effect of Trigonella Foenum Graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian J Physiol Pharmacol 1995;39(2):173-174
24. Dubuisson D.& Dennis SG. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 1977;4: 161-174.
25. Capone F & Aloisi, AM. Refinement of pain evaluation techniques. The formalin test. Ann. Ist. Super. Sanita 2004;40: 223-229
26. Wheeler-Aceto H & Cowan A. Standardization of the rat paw formalin test for the evaluation of analgesics. Psychopharmacology 1991; 104: 35-44.
27. Yagihashi S, Pathology and pathogenetic mechanisms of diabetic neuropathy, Diabetes Metab Rev 1995; 11:193.
28. Sumner CJ, Sheth, SJW, Griffin DR, Polydefkis CM. The spectrum of neuropathy in diabetes and impaired glucose tolerance. Neurology 2003; 60:108.
29. Vats V, Grover JK, Rathi SS. Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats. J Ethnopharmacol 2002;79:95-100.
30. Sharma RD, Sarkar A, Hazra DK. Hypolipidemic effect of fenugreek seeds: a chronic study in non-insulin dependent diabetic patients. Phytother Res 1996;10:332-4.
31. Puri D. Therapeutic potential of fenugreek. Indian J Physiol Pharmacol 1998;42:423-4.
32. Suja Pandian R, Anuradha CV, Viswanathan P. Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats. J Ethnopharmacol 2002;81:393-7.
33. Alarcon-Aguilara FJ, Roman-Ramos R, Perez-Gutierrez S. Study of the antihyperglycemic effect of plants used as anti-diabetics. J Ethnopharmacol 1998;61:101-10.
34. Ribes G, Sauvaire Y, Baccou JC, Valette G, Chenon D, Trimble E, et al. Effects of fenugreek seeds on endocrine pancreatic secretions in dogs. Ann Nutr Metab 1984;28:37-43.
35. Raghuram TC, Sharma RD, Sivakumar B, Sahay BK. Effect of fenugreek seeds on intravenous glucose disposition in Non-insulin dependent diabetic patients. Phytother Res 1994;8:83-6.
36. Sauvaire Y, Petti P, Broca C, Manteghetti M, Baissac Y, Fernandez-Alvarez J. 4-Hydroxyisoleucine: a novel amino acid potentiator of insulin secretion. Diabetes 1998;47(2):206-10
37. Smith AG, Russell JEL, Feldman, J Goldstein A, Peltier S & Smith. Lifestyle intervention for pre-diabetic neuropathy. Diabetes Care 2006;29:1294.
38. Ohkubo Y, Kishikawa H & Araki E. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus: a randomized prospective 6- year study. Diabetes Res Clin Pract, 1995;28:103.
39. Coppey LJ, Gellett JS, Davidson EP, Dunlap JA & Yorek MA. Effect of treating streptozotocin-induced diabetic rats with sorbinil, myoinositol or aminoguanidine on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve. Int J Exp Diabetes Res 2002; 3:21.
40. Van Dam PS, Van Asbeck BS, Van Oirschot JF, Biessels GJ, Hamers FP & Marx JJ. Glutathione and alpha-lipoate in diabetic rats: nerve function, blood flow and oxidative state. Eur J Clin Investig 2001; 31: 417.
41. Yoshizumi M, Tsuchiya K, Suzaki Y, Kirima K, Kyaw M, Moon J H, Terao J & Tamaki T. Quercetin glucuronide prevents VSMC hypertrophy by angiotensin II via the inhibition of JNK and AP-1 signaling pathway. Biochem Biophys Res Commun 2002; 293: 458.
42. Begum AN & Terao J. Protective effect of quercetin against cigarette tar extract-induced impairment of erythrocyte deformability. J Nutr Biochem 2002;13::265.
43. Janisch KM, Williamson G, Needs P & Plumb GW. Properties of quercetin conjugates: modulation of LDL oxidation and binding to human serum albumin. Free Radic Res 2004; 38: 877.
44. Genet S, Kale RK and Bequer NZ. Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonellafoenum graecum). Mol Cell Biochem 2002;236(1-2):7-12.
45. Shang M, Cais Han J, Li J. Studies on flavonoids from fenugreek (Trigonella foenum graecum L.). Zhongguo Zhong Yao Za Zhi 1999; 23:614-39
46. Kapur D. Neuropathic pain and diabetes. Diabetes/Metab. Res. Rev 2003;19:S9.
47. Cameron NE, Cotter M A & Maxfield V. Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats. Diabetologia 1993; 36:299