The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases

Biochemical Journal

Volumn 422, Issue 2, 2009, Pages 373-382

  Miyano, Kei ^a,b   Koga, Hirofumi ^a   Minakami, Reiko ^a,b   Sumimoto, Hideki ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Macrophage; NADPH oxidase; Nox family; Rac GTPase family; Superoxide

Indexed keywords

CATALYTIC CORE; CELL-FREE; CELLULAR LEVELS; CYTOCHROME B; GTPASES; NADPH OXIDASE; NOX FAMILY; PHAGOSOMES; RAC GTPASE FAMILY; RAC GTPASES; SUPEROXIDE; SUPEROXIDE PRODUCTION; SUPEROXIDES;

AMINES; AMINO ACIDS; CELL MEMBRANES; MACROPHAGES; MAMMALS; ORGANIC ACIDS; OXYGEN;

ENZYME INHIBITION;

IMMUNOGLOBULIN G; RAC1 PROTEIN; RAC2 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; GUANOSINE TRIPHOSPHATASE; RAC PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME METABOLISM; ENZYME REGULATION; GENE INSERTION; HELA CELL; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; AMINO ACID SEQUENCE; ANIMAL; COMPARATIVE STUDY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; TRANSPOSON;

MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DNA TRANSPOSABLE ELEMENTS; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NADPH OXIDASE; RAC GTP-BINDING PROTEINS; SUPEROXIDES;

EID: 70149122352     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20082182     Document Type: Article

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