Downregulation of MSP58 inhibits growth of human colorectal cancer cells via regulation of the cyclin D1-cyclin-dependent kinase 4-p21 pathway

Cancer Science

Volumn 100, Issue 9, 2009, Pages 1585-1590

  Shi, Hai ^a,b   Chen, Sunxiao ^c   Jin, Haifeng ^a,d   Xu, Chunsheng ^a   Dong, Guanglong ^a   Zhao, Qingchuan ^a   Wang, Weizhong ^a   Zhang, Hongwei ^a   Lin, Wei ^a   Zhang, Jing ^b   Davidovic, Laetitia ^e   Yao, Libo ^b   Fan, Daiming ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d BETHUNE INTERNATIONAL PEACE HOSPITAL   (China)

^e Equipe de Génétique et Biologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CCND1 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MCRS1 PROTEIN, HUMAN; MESSENGER RNA; NUCLEAR PROTEIN; RNA BINDING PROTEIN;

ARTICLE; CELL CYCLE; CELL FRACTIONATION; CELL PROLIFERATION; CLONOGENIC ASSAY; COLORECTAL TUMOR; COMPARATIVE STUDY; DOWN REGULATION; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; COLONY-FORMING UNITS ASSAY; COLORECTAL NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; NUCLEAR PROTEINS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED;

EID: 70149120704     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01223.x     Document Type: Article

References (28)

1. Parkin DM, Bray F, Ferlay J et al. Global cancer statistics. CA Cancer J Clin 2005; 55: 74-108.
2. Flamini E, Mercatali L, Nanni O et al. Free DNA and carcinoembryonic antigen serum levels: an important combination for diagnosis of colorectal cancer. Clin Cancer Res 2006; 12: 6985-8.
3. Jemal A, Tiwari RC, Murray T et al. American Cancer Society. Cancer statistics. CA Cancer J Clin 2004; 54: 8-29.
4. Kaz AM, Brentnall TA. Genetic testing for colon cancer. Nat Clin Prac Gastrol Hepat 2006; 3: 670-9.
5. Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005; 434: 843-50.
6. Ren Y, Busch RK, Perlaky L et al. The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120. Eur J Biochem 2005; 253: 734-42.
7. Davidovic L, Bechara E, Gravel M et al. The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons. Mol Genet 2006; 15: 1525-38.
8. Lin DY, Shih HM. Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration. J Biol Chem 2002; 277: 25 446-56.
9. Ivanova AV, Ivanov SV, Lerman ML. Association, mutual stabilization, and transcriptional activity of the STRA13 and MSP58 proteins. Cell Mol Life Sci 2005; 62: 471-84.
10. Shimono K, Shimono Y, Shimokata K et al. Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription. J Biol Chem 2005; 280: 39 436-47.
11. Okumura K, Zhao M, Depinho RA et al. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci USA 2005; 102: 2703-6.
12. Zhang J, Liu JY, Li X et al. The physical and functional interaction of NDRG2 with MSP58 in cells. Biochem Biophys Res Commun 2007; 352: 6-11.
13. Ma J, Jin H, Wang H et al. Expression of NDRG2 in clear cell renal cell carcinoma. Biol Pharm Bull 2008; 31: 1316-20.
14. Maaser K, Däubler P, Barthel B et al. Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis. Br J Cancer 2003; 88: 1217-22.
15. Choi SC, Kim KD, Kim JT et al. Expression and regulation of NDRG2 (Nmyc downstream regulated gene 2) during the differentiation of dendritic cells. FEBS Lett 2003; 553: 413-18.
16. Lin W, Zhang J, Zhang J et al. RNAi-mediated inhibition of MSP58 decreases tumor growth, migration and invasion in a human glioma cell line. J Cell Mol Med 2008; 15 (in press).
17. Jin HF, Pan YL, Zhao LN et al. p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia 2007; 9: 471-8.
18. Jin HF, Pan YL, He LJ et al. p75 neurotrophin receptor inhibits invasion and metastasis of gastric cancer. Mol Cancer Res 2007; 5: 423-33.
19. Simmons Kovacs LA, Orlando DA, Haase SB. Transcription networks and cyclin/CDKs: the yin and yang of cell cycle oscillators. Cell Cycle 2008; 7: 2626-9.
20. Brooks G. Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. Methods Mol Biol 2005; 296: 291-8.
21. Cresanta JL. Epidemiology of cancer in the United States. Prim Care 1992; 19: 419-41.
22. Greenwald P. Colon cancer overview. Cancer 1992; 70: 1206-15.
23. Pihl E, Hughes ES, McDermott FT et al. Disease-free survival and recurrence after resection of colorectal carcinoma. J Surg Oncol 1981; 16: 333-41.
24. Kjetil S, BjØrn SN, Jens-Christian K et al. Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: Potential implications for the surgical oncologist. Surg Oncol 2008; 6: 1-20.
25. Wilkins JA, Sansom OJ. C-Myc is a critical mediator of the phenotypes of Apc loss in the intestine. Cancer Res 2008; 68: 4963-6.
26. Chen J. Is Src the key to understanding metastasis and developing new treatments for colon cancer? Nat Clin Pract Gastroenterol Hepatol 2008; 5: 306-7.
27. Eng C. K-Ras and sensitivity to EGFR inhibitors in metastatic colorectal cancer. Clin Adv Hematol Oncol 2008; 6: 174-5.
28. Peschiaroli A, Figliola R, Coltella L et al. MyoD induces apoptosis in the absence of RB function through a p21(WAF1)-dependent re-localization of cyclin/cdk complexes to the nucleus. Oncogene 2002; 21: 8114-27.