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Volumn 4, Issue 2, 2009, Pages 98-108

Platelet resistance to antiplatelet drugs

Author keywords

Antiplatelet therapy; Aspirin; Clopidogrel; Percutaneous coronary intervention; Platelet resistance; Prasugrel and antiplatelet drugs

Indexed keywords

11 OXOTHROMBOXANE B2; ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CANGRELOR; CLOPIDOGREL; IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PRASUGREL; PROSTAGLANDIN SYNTHASE; THIENOPYRIDINE DERIVATIVE; THROMBOXANE B2; TICAGRELOR; TICLOPIDINE; TRA SCH 530348; UNCLASSIFIED DRUG; DRUG DERIVATIVE;

EID: 70149117757     PISSN: 15748901     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489009788452959     Document Type: Review
Times cited : (10)

References (112)
  • 1
    • 0028934985 scopus 로고
    • Individual variation in the effects of ASA on platelet function: Implications for the use of ASA clinically
    • Buchanan MR, Brister SJ. Individual variation in the effects of ASA on platelet function: Implications for the use of ASA clinically. Can J Cardiol 1995; 11: 221-227.
    • (1995) Can J Cardiol , vol.11 , pp. 221-227
    • Buchanan, M.R.1    Brister, S.J.2
  • 2
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002; 105: 1650-1655.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 3
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003; 107: 2908-2913.
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 5
    • 0027279350 scopus 로고
    • Two-year follow-up of aspirin responder and aspirin nonresponder. A pilot-study including 180 post-stroke patients
    • Grotemeyer KH, Scharafinski HW, Husstedt IW. Two-year follow-up of aspirin responder and aspirin nonresponder. A pilot-study including 180 post-stroke patients. Thromb Res 1993; 71: 397-403.
    • (1993) Thromb Res , vol.71 , pp. 397-403
    • Grotemeyer, K.H.1    Scharafinski, H.W.2    Husstedt, I.W.3
  • 6
    • 9844224482 scopus 로고    scopus 로고
    • Variable platelet response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty
    • Mueller MR, Salat A, Stangl P, et al. Variable platelet response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty. Thromb Haemost 1997; 78: 1003-1007.
    • (1997) Thromb Haemost , vol.78 , pp. 1003-1007
    • Mueller, M.R.1    Salat, A.2    Stangl, P.3
  • 7
    • 1542708471 scopus 로고    scopus 로고
    • Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment
    • Chen WH, Lee PY, Ng W, Tse HF, Lau CP. Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment. J Am Coll Cardiol 2004; 43: 1122-1126.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1122-1126
    • Chen, W.H.1    Lee, P.Y.2    Ng, W.3    Tse, H.F.4    Lau, C.P.5
  • 8
    • 33646761285 scopus 로고    scopus 로고
    • Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: Involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients
    • Ohmori T, Yatomi Y, Nonaka T, et al. Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: Involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients. J Thromb Haemost 2006; 4: 1271-1278.
    • (2006) J Thromb Haemost , vol.4 , pp. 1271-1278
    • Ohmori, T.1    Yatomi, Y.2    Nonaka, T.3
  • 9
    • 1242315475 scopus 로고    scopus 로고
    • Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization
    • Mobley JE, Bresee SJ, Wortham DC, Craft RM, Snider CC, Carroll RC. Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization. Am J Cardiol 2004; 93: 456-458.
    • (2004) Am J Cardiol , vol.93 , pp. 456-458
    • Mobley, J.E.1    Bresee, S.J.2    Wortham, D.C.3    Craft, R.M.4    Snider, C.C.5    Carroll, R.C.6
  • 10
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109: 3171-3175.
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 11
    • 27644536235 scopus 로고    scopus 로고
    • Platelet reactivity in patients and recurrent events poststenting:results of the prepare post-stenting study
    • Gurbel PA, Bliden KP, Guyer K, et al. Platelet reactivity in patients and recurrent events poststenting:results of the prepare post-stenting study. J Am Coll Cardiol 2005; 46: 1820-1826.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1820-1826
    • Gurbel, P.A.1    Bliden, K.P.2    Guyer, K.3
  • 12
    • 27644465874 scopus 로고    scopus 로고
    • Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST study
    • Gurbel PA, Bliden KP, Samara W, et al. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST study. J Am Coll Cardiol 2005; 46: 1827-1832.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1827-1832
    • Gurbel, P.A.1    Bliden, K.P.2    Samara, W.3
  • 13
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted clopidogrel loading doses according to vasodilator- stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance
    • Bonello L, Camoin-jau L, Arques S, et al. Adjusted clopidogrel loading doses according to vasodilator- stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance. J Am Coll Cardiol 2008; 51: 1404-1411.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1404-1411
    • Bonello, L.1    Camoin-jau, L.2    Arques, S.3
  • 14
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41: 961-965.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3    White, J.4    Topol, E.J.5
  • 15
    • 0035421783 scopus 로고    scopus 로고
    • Profile and prevalence of aspirin resistance in patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001; 88: 230-235.
    • (2001) Am J Cardiol , vol.88 , pp. 230-235
    • Gum, P.A.1    Kottke-Marchant, K.2    Poggio, E.D.3
  • 16
    • 0025997575 scopus 로고
    • Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients
    • Grotemeyer KH. Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients. Thromb Res 1991; 63: 587-593.
    • (1991) Thromb Res , vol.63 , pp. 587-593
    • Grotemeyer, K.H.1
  • 17
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel nonresponders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Muller I, Besta F, Schulz C, Massberg S, Schonig A, Gawaz M. Prevalence of clopidogrel nonresponders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89: 783-787.
    • (2003) Thromb Haemost , vol.89 , pp. 783-787
    • Muller, I.1    Besta, F.2    Schulz, C.3    Massberg, S.4    Schonig, A.5    Gawaz, M.6
  • 18
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel. Efficacy, safety and the issue of drug resistance
    • Cattaneo M. Aspirin and clopidogrel. Efficacy, safety and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004; 24: 1980-1987.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 19
    • 0141851094 scopus 로고    scopus 로고
    • Aspirin resistance: Definition, mechanisms and clinical read-outs
    • Patrono C. Aspirin resistance: Definition, mechanisms and clinical read-outs. J Thromb Haemost 2003; 1: 1710-1713.
    • (2003) J Thromb Haemost , vol.1 , pp. 1710-1713
    • Patrono, C.1
  • 20
  • 21
    • 23044435873 scopus 로고    scopus 로고
    • Variability in response to aspirin: Do we understand the clinical relevance?
    • Campbell CL, Steinhubl SR. Variability in response to aspirin: Do we understand the clinical relevance? J Thromb Haemost 2005; 3: 665-669.
    • (2005) J Thromb Haemost , vol.3 , pp. 665-669
    • Campbell, C.L.1    Steinhubl, S.R.2
  • 23
    • 18044378766 scopus 로고    scopus 로고
    • Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis
    • Savi P, Herbert JM. Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin Thromb Hemost 2005; 31: 174-183.
    • (2005) Semin Thromb Hemost , vol.31 , pp. 174-183
    • Savi, P.1    Herbert, J.M.2
  • 24
    • 27744516843 scopus 로고    scopus 로고
    • Absorption, metabolization, and antiplatelet effects of 300, 600, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE Trial
    • von Beckerath N, Taubert D, Pogatsa-Murray G, Schömig E, Kastrati A, Schömig A. Absorption, metabolization, and antiplatelet effects of 300, 600, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE Trial. Circulation 2005; 112: 2946-2950.
    • (2005) Circulation , vol.112 , pp. 2946-2950
    • von Beckerath, N.1    Taubert, D.2    Pogatsa-Murray, G.3    Schömig, E.4    Kastrati, A.5    Schömig, A.6
  • 25
    • 47649116687 scopus 로고    scopus 로고
    • Phramacotherapy of emerging novel platelet inhibitors
    • Angiolillo DJ, Capranzano P. Phramacotherapy of emerging novel platelet inhibitors. Am Heart J 2008; 156: S10-S15.
    • (2008) Am Heart J , vol.156
    • Angiolillo, D.J.1    Capranzano, P.2
  • 26
    • 54149097794 scopus 로고    scopus 로고
    • TRITON-TIMI 38 Investigators. Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial
    • Murphy SA, Antman EM, Wiviott SD, et al. TRITON-TIMI 38 Investigators. Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial. Eur Heart J 2008; 29: 2473-2479.
    • (2008) Eur Heart J , vol.29 , pp. 2473-2479
    • Murphy, S.A.1    Antman, E.M.2    Wiviott, S.D.3
  • 27
    • 56849130022 scopus 로고    scopus 로고
    • Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo
    • Erlinge D, Varenhorst C, Braun OO, et al. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. J Am Coll Cardiol 2008; 52: 1968-1977.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1968-1977
    • Erlinge, D.1    Varenhorst, C.2    Braun, O.O.3
  • 28
    • 0035899289 scopus 로고    scopus 로고
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 29
    • 33644499788 scopus 로고    scopus 로고
    • Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor
    • Ivandic BT, Schlick P, Staritz P, Kurz K, Katus HA, Giannitsis E. Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor. Clin Chem 2006; 52: 383-388.
    • (2006) Clin Chem , vol.52 , pp. 383-388
    • Ivandic, B.T.1    Schlick, P.2    Staritz, P.3    Kurz, K.4    Katus, H.A.5    Giannitsis, E.6
  • 30
    • 15944383861 scopus 로고    scopus 로고
    • Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases
    • Aleil B, Ravanat C, Cazenave JP, Rochoux G, Heitz A, Gachet C. Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases. J Thromb Haemost 2005; 3: 85-92.
    • (2005) J Thromb Haemost , vol.3 , pp. 85-92
    • Aleil, B.1    Ravanat, C.2    Cazenave, J.P.3    Rochoux, G.4    Heitz, A.5    Gachet, C.6
  • 31
    • 19644366172 scopus 로고    scopus 로고
    • Monitoring of clopidogrel action: Comparison of methods
    • Geiger J, Teichmann L, Grossmann R, et al. Monitoring of clopidogrel action: Comparison of methods. Clin Chem 2005; 51: 957-965.
    • (2005) Clin Chem , vol.51 , pp. 957-965
    • Geiger, J.1    Teichmann, L.2    Grossmann, R.3
  • 32
    • 10444281593 scopus 로고    scopus 로고
    • Variable extent of clopidogrel responsiveness in patients after coronary stenting
    • Grossmann R, Sokolova O, Schnurr A, et al. Variable extent of clopidogrel responsiveness in patients after coronary stenting. Thromb Haemost 2004; 92: 1201-1206.
    • (2004) Thromb Haemost , vol.92 , pp. 1201-1206
    • Grossmann, R.1    Sokolova, O.2    Schnurr, A.3
  • 33
    • 33645557848 scopus 로고    scopus 로고
    • The Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Platelet Function Analyzer (PFA)-100 closure time in the evaluation of platelet disorders and platelet function
    • Hayward CP, Harrison P, Cattaneo M, Ortel TL, Rao AK. The Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Platelet Function Analyzer (PFA)-100 closure time in the evaluation of platelet disorders and platelet function. J Thromb Haemost 2006; 4: 312-319.
    • (2006) J Thromb Haemost , vol.4 , pp. 312-319
    • Hayward, C.P.1    Harrison, P.2    Cattaneo, M.3    Ortel, T.L.4    Rao, A.K.5
  • 34
    • 18244392669 scopus 로고    scopus 로고
    • Screening for aspirin responsiveness after transient ischemic attack and stroke: Comparison of 2 point-of-care platelet function tests with optical aggregometry
    • Harrison P, Segal H, Blasbery K, Furtado C, Silver L, Rothwell PM. Screening for aspirin responsiveness after transient ischemic attack and stroke: Comparison of 2 point-of-care platelet function tests with optical aggregometry. Stroke 2005; 36: 1001-1005.
    • (2005) Stroke , vol.36 , pp. 1001-1005
    • Harrison, P.1    Segal, H.2    Blasbery, K.3    Furtado, C.4    Silver, L.5    Rothwell, P.M.6
  • 35
    • 33747157718 scopus 로고    scopus 로고
    • Frequency of aspirin resistance in a community hospital
    • Mirkhel A, Peyster E, Sundeen J, et al. Frequency of aspirin resistance in a community hospital. Am J Cardiol 2006; 98: 577-579.
    • (2006) Am J Cardiol , vol.98 , pp. 577-579
    • Mirkhel, A.1    Peyster, E.2    Sundeen, J.3
  • 36
    • 33745877645 scopus 로고    scopus 로고
    • Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel
    • Malinin A, Pokov A, Swaim L, Kotob M, Serebruany V. Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel. Methods Find Exp Clin Pharmacol 2006; 28: 315-322.
    • (2006) Methods Find Exp Clin Pharmacol , vol.28 , pp. 315-322
    • Malinin, A.1    Pokov, A.2    Swaim, L.3    Kotob, M.4    Serebruany, V.5
  • 37
    • 33646441600 scopus 로고    scopus 로고
    • Correlation of a new point-of-care test with conventional optical aggregometry or the assessment of clopidogrel responsiveness
    • von Beckerath N, Pogatsa-Murray G, Wieczorek A, Sibbing D, Schomig A, Kastrati A. Correlation of a new point-of-care test with conventional optical aggregometry or the assessment of clopidogrel responsiveness. Thromb Haemost 2006; 95: 910-911.
    • (2006) Thromb Haemost , vol.95 , pp. 910-911
    • von Beckerath, N.1    Pogatsa-Murray, G.2    Wieczorek, A.3    Sibbing, D.4    Schomig, A.5    Kastrati, A.6
  • 38
    • 33750083316 scopus 로고    scopus 로고
    • A head-to-head comparison between the VerifyNow P2Y12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention
    • van Werkum JW, van der Stelt CA, Seesing TH, Hackeng CM, ten Berg JM. A head-to-head comparison between the VerifyNow P2Y12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention. J Thromb Haemost 2006; 4: 2516-2518.
    • (2006) J Thromb Haemost , vol.4 , pp. 2516-2518
    • van Werkum, J.W.1    van der Stelt, C.A.2    Seesing, T.H.3    Hackeng, C.M.4    ten Berg, J.M.5
  • 39
    • 33749187494 scopus 로고    scopus 로고
    • Quantifying the effect of antiplatelet therapy: A comparison of the platelet function analyzer (PFA-100) and modified thromboelasto-graphy (mTEG) with light transmission platelet aggregometry
    • Agarwal S, Coakley M, Reddy K, Riddell A, Mallett S. Quantifying the effect of antiplatelet therapy: A comparison of the platelet function analyzer (PFA-100) and modified thromboelasto-graphy (mTEG) with light transmission platelet aggregometry. Anesthesiology 2006; 105: 676-683.
    • (2006) Anesthesiology , vol.105 , pp. 676-683
    • Agarwal, S.1    Coakley, M.2    Reddy, K.3    Riddell, A.4    Mallett, S.5
  • 40
    • 0041434848 scopus 로고    scopus 로고
    • Evaluation of a bedside platelet function assay: Performance and clinical utility
    • Lau WC, Walker T, Ogilby D, et al. Evaluation of a bedside platelet function assay: Performance and clinical utility. Ann Card Anesth 2002; 5: 33-42.
    • (2002) Ann Card Anesth , vol.5 , pp. 33-42
    • Lau, W.C.1    Walker, T.2    Ogilby, D.3
  • 42
    • 33644986263 scopus 로고    scopus 로고
    • Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers
    • Fontana P, Nolli S, Reber G, de Moerloose P. Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers. J Thromb Haemost 2006; 4: 813-819.
    • (2006) J Thromb Haemost , vol.4 , pp. 813-819
    • Fontana, P.1    Nolli, S.2    Reber, G.3    de Moerloose, P.4
  • 43
    • 33747088257 scopus 로고    scopus 로고
    • Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1 and cyclooxygenase-2-independent pathway: A 700-patient study of aspirin resistance
    • Frelinger AL III, Furman MI, Linden MD, et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1 and cyclooxygenase-2-independent pathway: A 700-patient study of aspirin resistance. Circulation 2006; 113: 2888-2896.
    • (2006) Circulation , vol.113 , pp. 2888-2896
    • Frelinger III, A.L.1    Furman, M.I.2    Linden, M.D.3
  • 44
    • 0023633423 scopus 로고
    • Paired analysis of urinary thromboxane B2 metabolites in humans
    • Catella F, FitzGerald GA. Paired analysis of urinary thromboxane B2 metabolites in humans. Thromb Res 1987; 47: 647-656.
    • (1987) Thromb Res , vol.47 , pp. 647-656
    • Catella, F.1    FitzGerald, G.A.2
  • 45
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative metaanalysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high-risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration. Collaborative metaanalysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high-risk patients. BMJ 2002; 324: 71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 46
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration
    • Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994; 308: 81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 47
    • 0037276966 scopus 로고    scopus 로고
    • Aspirin non-responder status in patients with recurrent cerebral ischemic attacks
    • Grundmann KJK, Kleine B, Dichgans J, et al. Aspirin non-responder status in patients with recurrent cerebral ischemic attacks. J Neurol 2003; 250: 63-66.
    • (2003) J Neurol , vol.250 , pp. 63-66
    • Grundmann, K.J.K.1    Kleine, B.2    Dichgans, J.3
  • 48
    • 10744230699 scopus 로고    scopus 로고
    • Incidence of aspirin nonresponsiveness using the Ultegra rapid platelet function assay-ASA
    • Wang JC, Aucoin-Barry D, Manuelian D, et al. Incidence of aspirin nonresponsiveness using the Ultegra rapid platelet function assay-ASA. Am J Cardiol 2003; 92: 1492-1494.
    • (2003) Am J Cardiol , vol.92 , pp. 1492-1494
    • Wang, J.C.1    Aucoin-Barry, D.2    Manuelian, D.3
  • 49
    • 4544387953 scopus 로고    scopus 로고
    • Magnitude and time course of platelet inhibition with Aggrenox and Aspirin in patients after ischemic stroke: The AGgrenox versus Aspirin Therapy Evaluation (AGATE) trial
    • Serebruany VL, Malinin AI, Sane DC, et al. Magnitude and time course of platelet inhibition with Aggrenox and Aspirin in patients after ischemic stroke: The AGgrenox versus Aspirin Therapy Evaluation (AGATE) trial. Eur J Pharmacol 2004; 499: 315-324.
    • (2004) Eur J Pharmacol , vol.499 , pp. 315-324
    • Serebruany, V.L.1    Malinin, A.I.2    Sane, D.C.3
  • 50
    • 10744228434 scopus 로고    scopus 로고
    • Lack of aspirin effect: Aspirin resistance or resistance to taking aspirin?
    • Cotter G, Shemesh E, Zehavi M, et al. Lack of aspirin effect: Aspirin resistance or resistance to taking aspirin? Am Heart J 2004; 147: 293-300.
    • (2004) Am Heart J , vol.147 , pp. 293-300
    • Cotter, G.1    Shemesh, E.2    Zehavi, M.3
  • 51
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
    • Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001; 345: 1809-1817.
    • (2001) N Engl J Med , vol.345 , pp. 1809-1817
    • Catella-Lawson, F.1    Reilly, M.P.2    Kapoor, S.C.3
  • 52
    • 33747125484 scopus 로고    scopus 로고
    • Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction
    • Gislason GH, Jacobsen S, Rasmussen JN, et al. Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction. Circulation 2006; 113: 2906-2913.
    • (2006) Circulation , vol.113 , pp. 2906-2913
    • Gislason, G.H.1    Jacobsen, S.2    Rasmussen, J.N.3
  • 53
    • 27744581956 scopus 로고    scopus 로고
    • Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease
    • Maree AO, Curtin RJ, Dooley M, et al. Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease. J Am Coll Cardiol 2005; 46: 1258-1263.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1258-1263
    • Maree, A.O.1    Curtin, R.J.2    Dooley, M.3
  • 54
    • 33747168513 scopus 로고    scopus 로고
    • Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers
    • Cox D, Maree AO, Dooley M, Conroy R, Byrne MF, Fitzgerald DJ. Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. Stroke 2006; 37: 2153-2158.
    • (2006) Stroke , vol.37 , pp. 2153-2158
    • Cox, D.1    Maree, A.O.2    Dooley, M.3    Conroy, R.4    Byrne, M.F.5    Fitzgerald, D.J.6
  • 55
    • 0023137593 scopus 로고
    • Inhibition of thromboxane formation in vivo and ex vivo: Implications for therapy with platelet inhibitory drugs
    • Reilly IA, FitzGerald GA. Inhibition of thromboxane formation in vivo and ex vivo: Implications for therapy with platelet inhibitory drugs. Blood 1987; 69: 180-186.
    • (1987) Blood , vol.69 , pp. 180-186
    • Reilly, I.A.1    FitzGerald, G.A.2
  • 56
    • 1542604069 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation by aspirin progressively decreases in long-term treated patients
    • Pulcinelli FM, Pignatelli P, Celestini A, et al. Inhibition of platelet aggregation by aspirin progressively decreases in long-term treated patients. J Am Coll Cardiol 2004; 43: 979-984.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 979-984
    • Pulcinelli, F.M.1    Pignatelli, P.2    Celestini, A.3
  • 57
    • 0034283498 scopus 로고    scopus 로고
    • Increased platelet aggregability during exercise in patients with previous myocardial infarction. Lack of inhibition by aspirin
    • Hurlen M, Seljeflot I, Arnesen H. Increased platelet aggregability during exercise in patients with previous myocardial infarction. Lack of inhibition by aspirin. Thromb Res 2000; 99: 487-494.
    • (2000) Thromb Res , vol.99 , pp. 487-494
    • Hurlen, M.1    Seljeflot, I.2    Arnesen, H.3
  • 58
    • 0028288681 scopus 로고
    • Norepinephrine-induced human platelet activation in vivo is only partly counteracted by aspirin
    • Larsson PT, Wallen NH, Hjemdahl P. Norepinephrine-induced human platelet activation in vivo is only partly counteracted by aspirin. Circulation 1994; 89:1951-1957.
    • (1994) Circulation , vol.89 , pp. 1951-1957
    • Larsson, P.T.1    Wallen, N.H.2    Hjemdahl, P.3
  • 59
    • 0034054309 scopus 로고    scopus 로고
    • Increased platelet sensitivity to collagen in individuals resistant to low-dose aspirin
    • Kawasaki T, Ozeki Y, Igawa T, et al. Increased platelet sensitivity to collagen in individuals resistant to low-dose aspirin. Stroke 2000; 31: 591-595.
    • (2000) Stroke , vol.31 , pp. 591-595
    • Kawasaki, T.1    Ozeki, Y.2    Igawa, T.3
  • 60
    • 1042268032 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression and inhibition in atherothrombosis
    • Cipollone F, Rocca B, Patrono C. Cyclooxygenase-2 expression and inhibition in atherothrombosis. Arterioscler Thromb Vasc Biol 2004; 24: 246-255.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 246-255
    • Cipollone, F.1    Rocca, B.2    Patrono, C.3
  • 61
    • 0031978582 scopus 로고    scopus 로고
    • Eicosanoids and iso-eicosanoids: Constitutive, inducible and transcellular biosynthesis in vascular disease
    • Maclouf J, Folco G, Patrono C. Eicosanoids and iso-eicosanoids: Constitutive, inducible and transcellular biosynthesis in vascular disease. Thromb Haemost 1998; 79: 691-705.
    • (1998) Thromb Haemost , vol.79 , pp. 691-705
    • Maclouf, J.1    Folco, G.2    Patrono, C.3
  • 62
    • 33751082074 scopus 로고    scopus 로고
    • Rapid stimulation of tyrosine phosphorylation signals downstream of G protein coupled receptors for thromboxane A2 in human platelets
    • Minuz P, Fumagalli L, Gaino S, et al. Rapid stimulation of tyrosine phosphorylation signals downstream of G protein coupled receptors for thromboxane A2 in human platelets. Biochem J 2006; 400: 127-134.
    • (2006) Biochem J , vol.400 , pp. 127-134
    • Minuz, P.1    Fumagalli, L.2    Gaino, S.3
  • 64
    • 0035124920 scopus 로고    scopus 로고
    • Platelet-active drugs: The relationships among dose, effectiveness, and side effects
    • Patrono C, Coller B, Dalen JE, et al. Platelet-active drugs: The relationships among dose, effectiveness, and side effects. Chest 2001; 119: S39-S63.
    • (2001) Chest , vol.119
    • Patrono, C.1    Coller, B.2    Dalen, J.E.3
  • 65
    • 0025572704 scopus 로고
    • A series of prostaglandin F2-like compounds are produced in vivo in humans by a noncyclooxygenase, free radical-catalyzed mechanism
    • Morrow JD, Hill KE, Burk RF, et al. A series of prostaglandin F2-like compounds are produced in vivo in humans by a noncyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 1990; 87: 9383-9387.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9383-9387
    • Morrow, J.D.1    Hill, K.E.2    Burk, R.F.3
  • 66
    • 0038364055 scopus 로고    scopus 로고
    • CD40-CD40L and platelet function: Beyond hemostasis
    • Freedman JE. CD40-CD40L and platelet function: Beyond hemostasis. Circ Res 2003; 92: 944-946.
    • (2003) Circ Res , vol.92 , pp. 944-946
    • Freedman, J.E.1
  • 67
    • 0014261604 scopus 로고
    • The effect of platelet age on platelet adherence to collagen
    • Hirsh J, Glynn MF, Mustard JF. The effect of platelet age on platelet adherence to collagen. J Clin Invest 1968; 47: 466-473.
    • (1968) J Clin Invest , vol.47 , pp. 466-473
    • Hirsh, J.1    Glynn, M.F.2    Mustard, J.F.3
  • 68
    • 0014528916 scopus 로고
    • Heterogeneity of human platelets. II. Functional evidence suggestive of young and old platelets
    • Karpatkin S. Heterogeneity of human platelets. II. Functional evidence suggestive of young and old platelets. J Clin Invest 1969; 48: 1083-1087.
    • (1969) J Clin Invest , vol.48 , pp. 1083-1087
    • Karpatkin, S.1
  • 69
    • 8144228106 scopus 로고    scopus 로고
    • Reticulated platelets in acute coronary syndrome: A marker of platelet activity
    • Lakkis N, Dokainish H, Abuzahra M, et al. Reticulated platelets in acute coronary syndrome: A marker of platelet activity. J Am Coll Cardiol 2004; 44: 2091-2093.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 2091-2093
    • Lakkis, N.1    Dokainish, H.2    Abuzahra, M.3
  • 70
    • 4644222788 scopus 로고    scopus 로고
    • Circulating reticulated platelets in the early and late phases after ischaemic stroke and transient ischaemic attack
    • McCabe DJ, Harrison P, Sidhu PS, Brown MM, Machin SJ. Circulating reticulated platelets in the early and late phases after ischaemic stroke and transient ischaemic attack. Br J Haematol 2004; 126: 861-869.
    • (2004) Br J Haematol , vol.126 , pp. 861-869
    • McCabe, D.J.1    Harrison, P.2    Sidhu, P.S.3    Brown, M.M.4    Machin, S.J.5
  • 71
    • 34247574729 scopus 로고    scopus 로고
    • Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin
    • Guthikonda S, Lev EI, Patel R, et al. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost 2007; 5: 490-496.
    • (2007) J Thromb Haemost , vol.5 , pp. 490-496
    • Guthikonda, S.1    Lev, E.I.2    Patel, R.3
  • 72
    • 49349102948 scopus 로고    scopus 로고
    • Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease
    • Guthikonda S, Alivar CL, Vaduganathan M, et al. Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease. J Am Coll Cardiol 2008; 52: 743-749.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 743-749
    • Guthikonda, S.1    Alivar, C.L.2    Vaduganathan, M.3
  • 73
    • 0042735242 scopus 로고    scopus 로고
    • Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T (GP Ia/IIa) and C-5T Kozak (GP Ib-alpha) polymorphisms
    • Macchi L, Christiaens L, Brabant S, et al. Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T (GP Ia/IIa) and C-5T Kozak (GP Ib-alpha) polymorphisms. J Am Coll Cardiol 2003; 42: 1115-1119.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1115-1119
    • Macchi, L.1    Christiaens, L.2    Brabant, S.3
  • 74
    • 0035960620 scopus 로고    scopus 로고
    • Pl(A2) polymorphism of beta(3) integrins is associated with enhanced thrombin generation and impaired antithrombotic action of aspirin at the site of microvascular injury
    • Undas A, Brummel K, Musial J, Mann KG, Szczeklik A. Pl(A2) polymorphism of beta(3) integrins is associated with enhanced thrombin generation and impaired antithrombotic action of aspirin at the site of microvascular injury. Circulation 2001; 104: 2666-2672.
    • (2001) Circulation , vol.104 , pp. 2666-2672
    • Undas, A.1    Brummel, K.2    Musial, J.3    Mann, K.G.4    Szczeklik, A.5
  • 75
    • 0036920113 scopus 로고    scopus 로고
    • Increased platelet-collagen interaction associated with double homozygosity for receptor polymorphisms of platelet GP Ia and GP IIIa
    • Pontiggia L, Lassila R, Pederiva S, Schmid HR, Burger M, Beer JH. Increased platelet-collagen interaction associated with double homozygosity for receptor polymorphisms of platelet GP Ia and GP IIIa. Arterioscler Thromb Vasc Biol 2002; 22: 2093-2098.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 2093-2098
    • Pontiggia, L.1    Lassila, R.2    Pederiva, S.3    Schmid, H.R.4    Burger, M.5    Beer, J.H.6
  • 76
    • 0035199930 scopus 로고    scopus 로고
    • Common variations in platelet glycoproteins: Pharmacogenomic implications
    • Quinn MJ, Topol EJ. Common variations in platelet glycoproteins: Pharmacogenomic implications. Pharmacogenomics 2001; 2: 341-352.
    • (2001) Pharmacogenomics , vol.2 , pp. 341-352
    • Quinn, M.J.1    Topol, E.J.2
  • 77
    • 0037256309 scopus 로고    scopus 로고
    • Genetic variation in cyclooxygenase 1: Effects on response to aspirin
    • Halushka MK, Walker LP, Halushka PV. Genetic variation in cyclooxygenase 1: Effects on response to aspirin. Clin Pharmacol Ther 2003; 73: 122-130.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 122-130
    • Halushka, M.K.1    Walker, L.P.2    Halushka, P.V.3
  • 78
    • 33745960402 scopus 로고    scopus 로고
    • Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the premier registry
    • Spertus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the premier registry. Circulation 2006; 113: 2803-2809.
    • (2006) Circulation , vol.113 , pp. 2803-2809
    • Spertus, J.A.1    Kettelkamp, R.2    Vance, C.3
  • 79
    • 0032814002 scopus 로고    scopus 로고
    • Clopidogrel loading dose regimens: Kinetic profile of pharmacodynamic response in healthy subjects
    • Savcic M, Hauert J, Bachmann F, Wyld PJ, Geudelin B, Cariou R. Clopidogrel loading dose regimens: Kinetic profile of pharmacodynamic response in healthy subjects. Semin Thromb Hemost 1999; 25(Suppl 2):15-19.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 2 , pp. 15-19
    • Savcic, M.1    Hauert, J.2    Bachmann, F.3    Wyld, P.J.4    Geudelin, B.5    Cariou, R.6
  • 80
    • 0036379817 scopus 로고    scopus 로고
    • Individual variations of platelet inhibition after loading doses of clopidogrel
    • Jaremo P, Lindahl TL, Fransson SG, Richter A. Individual variations of platelet inhibition after loading doses of clopidogrel. J Intern Med 2002; 252: 233-238.
    • (2002) J Intern Med , vol.252 , pp. 233-238
    • Jaremo, P.1    Lindahl, T.L.2    Fransson, S.G.3    Richter, A.4
  • 81
    • 0034762075 scopus 로고    scopus 로고
    • Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement
    • Muller I, Seyfarth M, Rudiger S, et al. Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement. Heart 2001; 85: 92-93.
    • (2001) Heart , vol.85 , pp. 92-93
    • Muller, I.1    Seyfarth, M.2    Rudiger, S.3
  • 82
    • 57549109044 scopus 로고    scopus 로고
    • The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel: The PRINC (Plavix Response in Coronary Intervention) Trial
    • Gladding P, Webster M, Zeng I, et al. The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel: The PRINC (Plavix Response in Coronary Intervention) Trial. J Am Coll Cardiol Interv 2008; 1; 612-619.
    • (2008) J Am Coll Cardiol Interv , vol.1 , pp. 612-619
    • Gladding, P.1    Webster, M.2    Zeng, I.3
  • 83
    • 4944261759 scopus 로고    scopus 로고
    • Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy
    • Kastrati A, von Beckerath N, Joost A, Pogatsa-Murray G, Gorchakova O, Schomig A. Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy. Circulation 2004; 110: 1916-1919.
    • (2004) Circulation , vol.110 , pp. 1916-1919
    • Kastrati, A.1    von Beckerath, N.2    Joost, A.3    Pogatsa-Murray, G.4    Gorchakova, O.5    Schomig, A.6
  • 84
    • 53449098101 scopus 로고    scopus 로고
    • Dose effect of clopidogrel reloading in patients already on 75-mg maintenance dose: The reload with clopidogrel before coronary angioplasty in subjects treated long term with dual antiplatelet therapy (RELOAD) study
    • Collet JP, Silvain J, Landivier A, et al. Dose effect of clopidogrel reloading in patients already on 75-mg maintenance dose: The reload with clopidogrel before coronary angioplasty in subjects treated long term with dual antiplatelet therapy (RELOAD) study. Circulation 2008; 118: 1225-1233.
    • (2008) Circulation , vol.118 , pp. 1225-1233
    • Collet, J.P.1    Silvain, J.2    Landivier, A.3
  • 85
    • 57549090390 scopus 로고    scopus 로고
    • Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention. Results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study
    • Aleil B, Jacquemin L, Poli FD, et al. Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention. Results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study. J Am Coll Cardiol Interv 2008; 1: 631-638.
    • (2008) J Am Coll Cardiol Interv , vol.1 , pp. 631-638
    • Aleil, B.1    Jacquemin, L.2    Poli, F.D.3
  • 87
    • 56949093392 scopus 로고    scopus 로고
    • CURRENT-OASIS 7 Steering Committee. Design and rationale of CURRENT-OASIS 7: A randomized, 2 x 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non-ST-elevation acute coronary syndromes managed with an early invasive strategy
    • Mehta SR, Bassand JP, Chrolavicius S, et al. CURRENT-OASIS 7 Steering Committee. Design and rationale of CURRENT-OASIS 7: A randomized, 2 x 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non-ST-elevation acute coronary syndromes managed with an early invasive strategy. Am Heart J 2008; 156: 1080-1088.
    • (2008) Am Heart J , vol.156 , pp. 1080-1088
    • Mehta, S.R.1    Bassand, J.P.2    Chrolavicius, S.3
  • 88
    • 4444353174 scopus 로고    scopus 로고
    • Pharmacokinetics of clopidogrel after administration of a high loading dose
    • Taubert D, Kastrati A, Harlfinger S, et al. Pharmacokinetics of clopidogrel after administration of a high loading dose. Thromb Haemost 2004; 92: 311-316.
    • (2004) Thromb Haemost , vol.92 , pp. 311-316
    • Taubert, D.1    Kastrati, A.2    Harlfinger, S.3
  • 90
    • 1642453779 scopus 로고    scopus 로고
    • Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance
    • Lau WC, Gurbel PA, Watkins PB, et al. Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation 2004; 109: 166-171.
    • (2004) Circulation , vol.109 , pp. 166-171
    • Lau, W.C.1    Gurbel, P.A.2    Watkins, P.B.3
  • 91
    • 6344226832 scopus 로고    scopus 로고
    • Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study
    • Serebruany VL, Midei MG, Malinin AI, et al. Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study. Arch Intern Med 2004; 164: 2051-2057.
    • (2004) Arch Intern Med , vol.164 , pp. 2051-2057
    • Serebruany, V.L.1    Midei, M.G.2    Malinin, A.I.3
  • 92
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51: 256-260
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3
  • 93
    • 57149104093 scopus 로고    scopus 로고
    • Siller-Matula JM, Spiel AO, Lang IM, Kreiner G, Christ G, Jilma B. Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel. Am Heart J 2009; 157: 148.e1-148.e5. doi:10.1016/ j.ahj.2008.09.017.
    • Siller-Matula JM, Spiel AO, Lang IM, Kreiner G, Christ G, Jilma B. Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel. Am Heart J 2009; 157: 148.e1-148.e5. doi:10.1016/ j.ahj.2008.09.017.
  • 94
    • 54349121974 scopus 로고    scopus 로고
    • Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
    • Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008; 52: 1557-1563.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1557-1563
    • Siller-Matula, J.M.1    Lang, I.2    Christ, G.3    Jilma, B.4
  • 95
    • 0037452681 scopus 로고    scopus 로고
    • Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding
    • Cattaneo M, Zighetti ML, Lombardi R, et al. Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. Proc Natl Acad Sci USA 2003; 100: 1978-1983.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1978-1983
    • Cattaneo, M.1    Zighetti, M.L.2    Lombardi, R.3
  • 96
    • 0035843178 scopus 로고    scopus 로고
    • Identification of the platelet ADP receptor targeted by antithrombotic drugs
    • Hollopeter G, Jantzen HM, Vincent D, et al. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature 2001; 409: 202-207.
    • (2001) Nature , vol.409 , pp. 202-207
    • Hollopeter, G.1    Jantzen, H.M.2    Vincent, D.3
  • 97
    • 29344466941 scopus 로고    scopus 로고
    • Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention. The role of dual drug resistance
    • Lev EI, Patel RT, Maresh K, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention. The role of dual drug resistance. J Am Coll Cardiol 2006; 47: 27-33.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 27-33
    • Lev, E.I.1    Patel, R.T.2    Maresh, K.3
  • 98
    • 0037101578 scopus 로고    scopus 로고
    • Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate
    • Macchi L, Christiaens L, Brabant S, et al. Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate. Thromb Res 2002; 107: 45-49.
    • (2002) Thromb Res , vol.107 , pp. 45-49
    • Macchi, L.1    Christiaens, L.2    Brabant, S.3
  • 99
    • 49349114160 scopus 로고    scopus 로고
    • Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents
    • Gori AM, Marcucci R, Migliorini A, et al. Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents. J Am Coll Cardiol 2008; 52: 734-739.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 734-739
    • Gori, A.M.1    Marcucci, R.2    Migliorini, A.3
  • 100
    • 21644448736 scopus 로고    scopus 로고
    • Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: Results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial
    • Wiviott SD, Antman EM, Winters KJ, et al. Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: Results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial. Circulation 2005; 111: 3366-3373.
    • (2005) Circulation , vol.111 , pp. 3366-3373
    • Wiviott, S.D.1    Antman, E.M.2    Winters, K.J.3
  • 101
    • 37849002889 scopus 로고    scopus 로고
    • Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin treated patients with coronary artery disease
    • Wallentin L, Varenhorst C, James S, et al. Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin treated patients with coronary artery disease. Eur Heart J 2008; 29: 21-30.
    • (2008) Eur Heart J , vol.29 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3
  • 102
    • 36148983750 scopus 로고    scopus 로고
    • TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al., TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007; 357: 2001-2015.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 103
    • 70350104623 scopus 로고    scopus 로고
    • TRITON-TIMI 38 Investigators. Prasugrel compared with clopidogrel in ST-elevation myocardial infarction patients undergoing percutaneous coronary intervention
    • Montaslescot G. TRITON-TIMI 38 Investigators. Prasugrel compared with clopidogrel in ST-elevation myocardial infarction patients undergoing percutaneous coronary intervention. European Society of Cardiology (ESC) Congress 2008.
    • (2008) European Society of Cardiology (ESC) Congress
    • Montaslescot, G.1
  • 104
    • 37849002889 scopus 로고    scopus 로고
    • Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
    • Wallentin L, Varenhorst C, James S, et al. Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J 2008; 29: 21-30.
    • (2008) Eur Heart J , vol.29 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3
  • 105
    • 70350121310 scopus 로고    scopus 로고
    • A Study of the Antiplatelet Effects Comparing AZD6140 With Clopidogrel Responder and Non-Responders(RESPOND). Available at: http://clinicaltrials.gov/ct2/show/NCT00642811. Accessed on: December 30, 2008.
    • A Study of the Antiplatelet Effects Comparing AZD6140 With Clopidogrel Responder and Non-Responders(RESPOND). Available at: http://clinicaltrials.gov/ct2/show/NCT00642811. Accessed on: December 30, 2008.
  • 107
    • 70350098996 scopus 로고    scopus 로고
    • A Clinical Trial to Demonstrate the Efficacy of Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition PCI. Available at:, Accessed on: December 30, 2008
    • A Clinical Trial to Demonstrate the Efficacy of Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition PCI. Available at: http://clinicaltrials.gov/ct2/show/NCT00305162. Accessed on: December 30, 2008.
  • 108
    • 70350110169 scopus 로고    scopus 로고
    • Trial to Assess the Effects of SCH 530348 in Preventing Heart Attack and Stroke in Patients With Acute Coronary Syndrome (TRA•CER). Available at: http://clinicaltrials.gov/ct2/show/NCT00527943. Accessed on: December, 2008.
    • Trial to Assess the Effects of SCH 530348 in Preventing Heart Attack and Stroke in Patients With Acute Coronary Syndrome (TRA•CER). Available at: http://clinicaltrials.gov/ct2/show/NCT00527943. Accessed on: December, 2008.
  • 110
    • 70350104624 scopus 로고    scopus 로고
    • Christie, D.J.: WO2008005771A2 (2008).
    • Christie, D.J.: WO2008005771A2 (2008).
  • 112
    • 60049093774 scopus 로고    scopus 로고
    • Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: Implications for aspirin "resistance
    • Santilli F, Rocca B, De Cristofaro R, et al. Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: Implications for aspirin "resistance". J Am Coll Cardiol 2009; 53: 667-677.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 667-677
    • Santilli, F.1    Rocca, B.2    De Cristofaro, R.3


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