Ion-blocking sites of the Kir2.1 channel revealed by multiscale modeling

Biochemistry

Volumn 48, Issue 36, 2009, Pages 8758-8763

  Tai, Kaihsu ^a   Stansfeld, Phillip J ^a   Sansom, Mark S P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCKING SITES; CYTOPLASMIC DOMAINS; EN-ROUTE; INTERACTION SITE; INTRACELLULAR DOMAIN; INWARD-RECTIFYING; MOLECULAR DYNAMICS SIMULATIONS; MULTI-SCALE MODELING; MULTIVALENT IONS; POTASSIUM CHANNELS;

BINDING ENERGY; CELLS; CYTOLOGY; DISTILLATION; IONS; MAGNESIUM; MOLECULAR DYNAMICS;

BINDING SITES;

ASPARAGINE; GLUTAMIC ACID; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; ION; MAGNESIUM; SPERMINE;

ARTICLE; BINDING KINETICS; BINDING SITE; CHANNEL GATING; CHEMICAL BINDING; CONTROLLED STUDY; CYTOPLASM; ELECTRICITY; ENTROPY; INHIBITION KINETICS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; SIMULATION; STRUCTURAL HOMOLOGY;

ANIMALS; COMPUTER SIMULATION; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HUMANS; ION CHANNEL GATING; MAGNESIUM; MICE; MODELS, MOLECULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, TERTIARY; SPERMIDINE; SPERMINE; STATIC ELECTRICITY; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS;

EID: 70149115914     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9007808     Document Type: Article

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