Spermine block of the strong inward rectifier potassium channel Kir2.1: Dual roles of surface charge screening and pore block

Journal of General Physiology

Volumn 120, Issue 1, 2002, Pages 53-66

  Xie, Lai Hua ^a   John, Scott A ^a   Weiss, James N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Inward rectification; K+ channels; Modeling; Polyamine; Spermine

Indexed keywords

MAGNESIUM ION; POLYAMINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SPERMINE;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; ELECTRIC POTENTIAL; FEMALE; GENETIC TRANSFECTION; IONIC STRENGTH; MODEL; MUTAGENESIS; NONHUMAN; OOCYTE; PATCH CLAMP; POTASSIUM CURRENT; POTASSIUM TRANSPORT; SURFACE CHARGE; XENOPUS; ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE POTENTIAL; CELL STRAIN COS1; ELECTROPHYSIOLOGY; OSMOLARITY;

ANIMAL; COS CELLS; ELECTROPHYSIOLOGY; FEMALE; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; OOCYTES; OSMOLAR CONCENTRATION; SPERMINE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; XENOPUS; ANIMALS;

EID: 0036020151     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.20028576     Document Type: Article

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