Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca

Journal of Biological Chemistry

Volumn 283, Issue 23, 2008, Pages 16068-16076

  Ding, Yousong ^a   Williams, Robert M ^b,c   Sherman, David H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; AMINES; AMINO ACIDS; BIOCHEMISTRY; CATALYSTS; ENZYME ACTIVITY; METABOLISM; METABOLITES; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC ACIDS; POLYPEPTIDES; PROTEINS;

AMINO ACID RESIDUES; BIOLOGICAL ACTIVITIES; BIOSYNTHETIC ENZYMES; COFACTOR; COMPETITIVE INHIBITORS; COMPLEX MOLECULES; DIVALENT CATIONS; ENZYME INHIBITORS; ENZYME SPECIFICITIES; ERGOT ALKALOIDS; IN CELLS; MOLECULAR ANALYSIS; NATURAL PRODUCTS; NEW CLASSES; POLYPEPTIDE SEQUENCES; PRENYLTRANSFERASE; PRENYLTRANSFERASE ENZYMES; PROTEIN TRAFFICKING; RELATIVE ACTIVITIES; SECONDARY METABOLISMS; SECONDARY METABOLITES; SIMPLE MODIFICATIONS; SYNTHASE;

ENZYMES;

4 DIMETHYLALLYLTRYPTOPHAN SYNTHASE; ASPARTIC ACID; DIMETHYLALLYLTRANSFERASE; EDETIC ACID; LYSINE; THREONINE; TRYPTOPHAN; UNCLASSIFIED DRUG; ENZYME INHIBITOR; FUNGAL PROTEIN; TRANSFERASE; TRYPTOPHAN DIMETHYLALLYLTRANSFERASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME MODIFICATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; FUNGUS; MALBRANCHEA AURANTIACA; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; GENOME; KINETICS; MOLECULAR GENETICS; ONYGENALES; PROTEIN MOTIF; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI; MALBRANCHEA; MALBRANCHEA AURANTIACA; PROKARYOTA;

ALKYL AND ARYL TRANSFERASES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; DIMETHYLALLYLTRANSTRANSFERASE; EDETIC ACID; ENZYME INHIBITORS; FUNGAL PROTEINS; GENOME, FUNGAL; KINETICS; MOLECULAR SEQUENCE DATA; ONYGENALES; SEQUENCE ALIGNMENT; TRYPTOPHAN;

EID: 47049111183     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801991200     Document Type: Article

References (40)

1. Keller, N. P., Turner, G., and Bennett, J. W. (2005) Nat. Rev. Microbiol. 3, 937-947
2. Gin, A. S., and Zhanel, G. G. (1996) Ann. Pharmacol. 30, 615-624
3. Walsh, C. (2003) Nat. Rev. Microbiol. 1, 65-70
4. Spurgeon, D. (2007) Bmj. 335, 961
5. Pelaez, F. (2005) in Handbook of Industrial Mycology (An, Z. ed), Marcel Dekker, New York
6. Chiung, Y. M., Fujita, T., Nakagawa, M., Nozaki, H., Chen, G. Y., Chen, Z. C., and Nakayama, M. (1993) J. Antibiot. (Tokyo) 46, 1819-1826
7. Martinez-Luis, S., Gonzalez, M. C., Ulloa, M., and Mata, R. (2005) Phytochemistry 66, 1012-1016
8. Martinez-Luis, S., Rodriguez, R., Acevedo, L., Gonzalez, M. C., Lira-Rocha, A., and Mata, R. (2006) Tetrahedron 62, 1817-1822
9. Schlegel, B., Hanel, F., Gollmick, F. A., Saluz, H. P., and Grafe, U. (2003) J. Antibiot. (Tokyo) 56, 917-922
10. Schlegel, B., Hartl, A., Gollmick, F. A., and Grafe, U. (2003) J. Antibiot. (Tokyo) 56, 792-794
11. Liang, P. H., Ko, T. P., and Wang, A. H. (2002) Eur. J. Biochem. 269, 3339-3354
12. Walsh, C. T. (2007) ACS Chem. Biol. 2, 296-298
13. Chen, A., Kroon, P. A., and Poulter, C. D. (1994) Protein Sci. 3, 600-607
14. Wu, Z., Demma, M., Strickland, C. L., Radisky, E. S., Poulter, C. D., Le, H. V., and Windsor, W. T. (1999) Biochemistry 38, 11239-11249
15. Wildung, M. R., and Croteau, R. (1996) J. Biol. Chem. 271, 9201-9204
16. Starks, C. M., Back, K., Chappell, J., and Noel, J. P. (1997) Science 277, 1815-1820
17. Balibar, C. J., Howard-Jones, A. R., and Walsh, C. T. (2007) Nat. Chem. Biol. 3, 584-592
18. Edwards, D. J., and Gerwick, W. H. (2004) J. Am. Chem. Soc. 126, 11432-11433
19. Gebler, J. C., and Poulter, C. D. (1992) Arch. Biochem. Biophys. 296, 308-313
20. Grundmann, A., and Li, S. M. (2005) Microbiology 151, 2199-2207
21. Haagen, Y., Unsold, I., Westrich, L., Gust, B., Richard, S. B., Noel, J. P., and Heide, L. (2007) FEBS Lett. 581, 2889-2893
22. Kremer, A., Westrich, L., and Li, S. M. (2007) Microbiology 153, 3409-3416
23. Pojer, F., Wemakor, E., Kammerer, B., Chen, H., Walsh, C. T., Li, S. M., and Heide, L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 2316-2321
24. Steffan, N., Unsold, I. A., and Li, S. M. (2007) Chembiochem. 8, 1298-1307
25. Unsold, I. A., and Li, S. M. (2005) Microbiology 151, 1499-1505
26. Unsold, I. A., and Li, S. M. (2006) Chembiochem. 7, 158-164
27. Yin, W. B., Ruan, H. L., Westrich, L., Grundmann, A., and Li, S. M. (2007) Chembiochem. 8, 1154-1161
28. Ohara, K., Yamamoto, K., Hamamoto, M., Sasaki, K., and Yazaki, K. (2006) Plant Cell Physiol. 47, 581-590
29. Kuzuyama, T., Noel, J. P., and Richard, S. B. (2005) Nature 435, 983-987
30. Sambrook, J., and Russel, D. W. (2001) Molecular Cloning - A Laboratory Manual, Cold Spring Harbor Laboratory Press, New York
31. Liu, Y. G., and Whittier, R. F. (1995) Genomics 25, 674-681
32. Shah, M. M., Grover, T. A., Barr, D. P., and Aust, S. D. (1992) J. Biol. Chem. 267, 21564-21569
33. Bhattacharyya, D. K., Adak, S., Bandyopadhyay, U., and Banerjee, R. K. (1994) Biochem. J. 298, 281-288
34. Carvajal, N., Orellana, M. S., Borquez, J., Uribe, E., Lopez, V., and Salas, M. (2004) J. Inorg. Biochem. 98, 1465-1469
35. Cress, W. A., Chayet, L. T., and Rilling, H. C. (1981) J. Biol. Chem. 256, 10917-10923
36. Tsai, H. F., Wang, H., Gebler, J. C., Poulter, C. D., and Schardl, C. L. (1995) Biochem. Biophys. Res. Commun. 216, 119-125
37. Lam, K. S. (2007) Trends Microbiol. 15, 279-289
38. Peraica, M., Radic, B., Lucic, A., and Pavlovic, M. (1999) Bull. World Health Organ. 77, 754-766
39. Chan, H. T., and Anthony, C. (1992) FEMS Microbiol. Lett. 75, 231-234
40. Gebler, J. C., Woodside, A. B., and Poulter, C. D. (1992) J. Am. Chem. Soc. 114, 7354-7360