Stem cell transplantation modulates mRNA gene expression profile in doxorubicin-induced cardiomyopathy

Journal of Stem Cells

Volumn 3, Issue 4, 2008, Pages 235-244

  Garbade, Jens ^a   Schubert, Andreas ^a   Barten, Markus J ^a,b   Aupperle, Heike ^a   Arsalan, Mani ^a   Borger, Michael A ^a   Jacobs, Stefan ^a   Dhein, Stefan ^a   Mohr, Friedrich Wilhelm ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Bone marrow derived stem cell; Cardiomyopathy; Gene expression; Myocardial regeneration; Transplantation

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; DOXORUBICIN; MESSENGER RNA; SOMATOMEDIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BONE MARROW CELL; CARDIOMYOPATHY; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EXPERIMENTAL RABBIT; FLUORESCENCE MICROSCOPY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART RIGHT VENTRICLE; HEART VENTRICLE FUNCTION; HEART VENTRICLE SEPTUM; HISTOPATHOLOGY; MALE; NONHUMAN; PARACRINE SIGNALING; TISSUE DISTRIBUTION; UPREGULATION;

ORYCTOLAGUS CUNICULUS;

EID: 70049113963     PISSN: 15568539     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Dimmeler S, Zeiher AM, Schneider MD. Unchain my heart: the scientific foundations of cardiac repair. J. Clin. Invest. 115, 572, 2005.
2. Bartunek J, Dimmeler S, Drexler H, Fernandez-Aviles F, Galinanes M, Janssens S, Martin J, Mathur A, Menasche P, Priori S, Strauer B, Tendera M, Wijns W, Zeiher A; task force of the European Society of Cardiology. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Eur. Heart J. 27, 1338, 2006.
3. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature 410, 702, 2001.
4. Tomita S, Li RK, Weisel RD, Mickle DA, Kim EF, Sakai T, Jia FQ. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 100, 247, 1999.
5. Nagaya N, Kangawa K, Itoh T, Iwase T, Murakami S, Miyahara Y, Fujii T, Uematsu M, Ohgushi H, Yamagishi M, Tokudome T, Mori H, Miyatake K, Kitamura S. Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy. Circulation 112, 1128, 2005.
6. Agbulut O, Menot ML, Li Z, Marotte F, Paulin D, Hagege AA, Chomienne C, Samuel JL, Menasche P. Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathy. Cardiovasc Res.58, 451, 2003.
7. Suzuki K, Murtuza B, Suzuki N, Smolenski RT, Yacoub MR. Intracoronary infusion of skeletal myoblasts improves cardiac function in doxorubicin-induced heart failure. Circulation 104, 1213, 2001.
8. Pelacho B, Aranguren XL, Mazo M, Abizanda G, Gavira JJ, Clavel C, Gutierrez-Perez M, Luttun A, Verfaillie CM, Prosper F. Plasticity and cardiovascular applications of multipotent adult progenitor cells.Nat Clin Pract Cardiovasc. Med. 4, S15, 2007.
9. Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M, Pasumarthi KB, Virag JI, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428, 668, 2004.
10. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 428, 664, 2004.
11. Lyngbaek S, Schneider M, Hansen JL, Sheikh SP. Cardiac regeneration by resident stem and progenitor cells in the adult heart. Basic Res. Cardiol. 102, 101, 2007.
12. Lu C, Arai M, Misao Y, Chen X, Wang N, Onogi H, Kobayashi H, Uno Y, Takemura G, Minatoguchi S, Fujiwara T, Fujiwara H. Autologous bone marrow cell transplantation improves left ventricular function in rabbit hearts with cardiomyopathy via myocardial regeneration-unrelated mechanisms. Heart Vessels 21, 180, 2006.
13. Spinale FG, Coker ML, Heung LJ, Bond BR, Gunasinghe HR, Etoh T, Goldberg AT, Zellner JL, Crumbley AJ. A matrix metalloproteinase induction/ activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation 102, 1944, 2000.
14. Tyagi SC, Kumar S, Voelker DJ, Reddy HY, Janicki JS, Curtis JJ. Differential gene expression of extracellular matrix components in dilated cardiomyopathy. J. Cell Biochem. 63, 185, 1996.
15. Gnecchi M, He H, Noiseux N, Liang OD, Zhang L, Morello F, Mu H, Melo LG, Pratt RE, Ingwall JS, Dzau VJ. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J. 20, 661, 2006.
16. Fazel S, Cimini M, Chen L, Li S, Angoulvant D, Fedak P, Verma S, Weisel RD, Keating A, Li RK. Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J. Clin. Invest 116, 1865, 2006.
17. Dhein S, Garbade J, Rouabah D, Abraham G, Ungemach FR, Schneider K, Ullmann C, Aupperle H, Gummert JF, Mohr FW. Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure. J. Cardiothorac. Surg. 26, 17, 2006.
18. Aupperle H, Garbade J, Schubert A, Barten M, Dhein S, Schoon HA, Mohr FW. Effects of autologous stem cells on immunohistochemical patterns and gene expression of metalloproteinases and their tissue inhibitors in Doxorubicin cardiomyopathy in a rabbit model. Vet. Pathol. 44, 494, 2007.
19. Kinnaird T, Stabile E, Burnett MS, Shou M, Lee CW, Barr S, Fuchs S, Epstein SE. Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation. 2004 Mar 30;109(12):1543-9. Epub 2004 Mar 15. Erratum in: Circulation 112, 73, 2005.
20. Cittadini A, Stromer H, Katz SE, Clark R, Moses AC, Morgan JP, Douglas PS. Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation. Circulation 93, 800, 1996.
21. Duerr RL, McKirnan MD, Gim RD, Clark RG, Chien KR, Ross J Jr. Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat. Circulation 93, 2188, 1996.
22. Xu M, Uemura R, Dai Y, Wang Y, Pasha Z, Ashraf M. In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. J. Mol. Cell Cardiol. 42, 441, 2007.
23. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, Pan J, Sano M, Takahashi T, Hori S, Abe H, Hata J, Umezawa A, Ogawa S, Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 103:697-705, 1999.
24. Garbade J, Schubert A, Scheffler A, Walther T, Gummert J, Dhein S, Mohr WF. Transdifferentiation and cell-fusion are two different ways of bone marrow stromal cells to develop into cardiac lineage. Thorac. Cardiovasc. Surg. 53, 2005.