Characterization of a microsphere formulation containing glucose oxidase and its in vivo efficacy in a murine solid tumor model

Pharmaceutical Research

Volumn 26, Issue 10, 2009, Pages 2343-2357

  Liu, Qun ^a   Rauth, Andrew Michael ^b   Liu, Jiang ^b   Babakhanian, Karlo ^a   Wang, Xinyue ^a   Bendayan, Reina ^a   Wu, Xiao Yu ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Antitumor activity; Glucose oxidase; Intratumoral delivery; Microspheres; Reactive oxygen species

Indexed keywords

CALCIUM ALGINATE; CHITOSAN; GLUCOSE OXIDASE; MICROSPHERE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; FEMALE; HISTOPATHOLOGY; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR; TUMOR GROWTH; X RAY PHOTOELECTRON SPECTROSCOPY;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DISEASE MODELS, ANIMAL; FEMALE; GLUCOSE OXIDASE; HUMANS; MICE; MICE, INBRED BALB C; MICROSPHERES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 69949179167     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9951-x     Document Type: Article

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