Cytotoxicity and mechanism of action of a new ROS-generating microsphere formulation for circumventing multidrug resistance in breast cancer cells

Breast Cancer Research and Treatment

Volumn 121, Issue 2, 2010, Pages 323-333

  Liu, Qun ^a   Shuhendler, Adam ^a   Cheng, Ji ^a   Rauth, Andrew Michael ^b   O'Brien, Peter ^a   Wu, Xiao Yu ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Breast cancer; Cytotoxicity; Microspheres; Multidrug resistance; Reactive oxygen species

Indexed keywords

ALGINIC ACID; AMITROLE; BUTHIONINE SULFOXIMINE; CATALASE; CHITOSAN; CICLOPIROXOLAMINE; DEFEROXAMINE MESYLATE; DIETHYLDITHIOCARBAMIC ACID; GLUCOSE OXIDASE; GLYCOPROTEIN P; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPID; MICROSPHERE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG FORMULATION; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; GENE OVEREXPRESSION; LIPID PEROXIDATION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; MICE; MICROSPHERES; REACTIVE OXYGEN SPECIES;

EID: 77953024814     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0473-3     Document Type: Article

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