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Volumn 3, Issue 2, 2009, Pages 187-196

Therapies for scleroderma-related pulmonary arterial hypertension

Author keywords

Endothelin receptor antagonist; Phosphodiesterase inhibitor; Prostaglandin; Pulmonary arterial hypertension; Scleroderma; Therapy

Indexed keywords

AMBRISENTAN; ANTIINFLAMMATORY AGENT; BOSENTAN; CALCIUM CHANNEL BLOCKING AGENT; ENDOTHELIN RECEPTOR ANTAGONIST; ILOPROST; IMATINIB; PHOSPHODIESTERASE INHIBITOR; PLACEBO; PROSTACYCLIN; PROSTAGLANDIN DERIVATIVE; PROTEIN TYROSINE KINASE INHIBITOR; SILDENAFIL; SITAXSENTAN; SORAFENIB; UNIPROST; WARFARIN;

EID: 69949178696     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.09.5     Document Type: Review
Times cited : (24)

References (92)
  • 1
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann. Intern. Med. 115(5), 343-349 (1991).
    • (1991) Ann. Intern. Med , vol.115 , Issue.5 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 2
    • 0032578279 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet 352, 719-725 (1998).
    • (1998) Lancet , vol.352 , pp. 719-725
    • Gaine, S.P.1    Rubin, L.J.2
  • 3
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension. A national prospective study
    • Rich S, Dantzker DR, Ayres SM et al. Primary pulmonary hypertension. A national prospective study. Ann. Intern. Med. 107(2), 216-223 (1987).
    • (1987) Ann. Intern. Med , vol.107 , Issue.2 , pp. 216-223
    • Rich, S.1    Dantzker, D.R.2    Ayres, S.M.3
  • 4
    • 2942522878 scopus 로고    scopus 로고
    • Clinical classification of pulmonary hypertension
    • Simonneau G, Galie N, Rubin LJ et al. Clinical classification of pulmonary hypertension. J. Am. Coll. Cardiol. 43(12 Suppl.), S5-S12 (2004).
    • (2004) J. Am. Coll. Cardiol , vol.43 , Issue.12 SUPPL.
    • Simonneau, G.1    Galie, N.2    Rubin, L.J.3
  • 5
    • 14044274307 scopus 로고    scopus 로고
    • The right ventricle in pulmonary hypertension
    • Chin KM, Kim NH, Rubin LJ. The right ventricle in pulmonary hypertension. Coron. Artery Dis. 16(1), 13-18 (2005).
    • (2005) Coron. Artery Dis , vol.16 , Issue.1 , pp. 13-18
    • Chin, K.M.1    Kim, N.H.2    Rubin, L.J.3
  • 6
    • 1642453778 scopus 로고    scopus 로고
    • Endothelial dysfunction in pulmonary hypertension
    • Budhiraja R, Tuder RM, Hassoun PM. Endothelial dysfunction in pulmonary hypertension. Circulation 109(2), 159-165 (2004).
    • (2004) Circulation , vol.109 , Issue.2 , pp. 159-165
    • Budhiraja, R.1    Tuder, R.M.2    Hassoun, P.M.3
  • 7
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N. Engl. J. Med. 351(14), 1425-1436 (2004).
    • (2004) N. Engl. J. Med , vol.351 , Issue.14 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 8
    • 0037331116 scopus 로고    scopus 로고
    • Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosis
    • Kawut SM, Taichman DB, Archer-Chicko CL, Palevsky HI, Kimmel SE. Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosis. Chest 123(2), 344-350 (2003).
    • (2003) Chest , vol.123 , Issue.2 , pp. 344-350
    • Kawut, S.M.1    Taichman, D.B.2    Archer-Chicko, C.L.3    Palevsky, H.I.4    Kimmel, S.E.5
  • 9
    • 33749329543 scopus 로고    scopus 로고
    • Clinical differences between idiopathic and scleroderma-related pulmonary hypertension
    • Fisher MR, Mathai SC, Champion HC et al. Clinical differences between idiopathic and scleroderma-related pulmonary hypertension. Arthritis Rheum. 54(9), 3043-3050 (2006).
    • (2006) Arthritis Rheum , vol.54 , Issue.9 , pp. 3043-3050
    • Fisher, M.R.1    Mathai, S.C.2    Champion, H.C.3
  • 10
    • 0035038492 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic sclerosis: Risk factors for progression and consequences for survival
    • MacGregor AJ, Canavan R, Knight C et al. Pulmonary hypertension in systemic sclerosis: risk factors for progression and consequences for survival. Rheumatology (Oxford) 40(4), 453-459 (2001).
    • (2001) Rheumatology (Oxford) , vol.40 , Issue.4 , pp. 453-459
    • MacGregor, A.J.1    Canavan, R.2    Knight, C.3
  • 11
    • 49649095907 scopus 로고    scopus 로고
    • Right ventricular contractility in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension
    • Overbeek MJ, Lankhaar JW, Westerhof N et al. Right ventricular contractility in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. Eur. Respir. J. 31(6), 1160-1166 (2008).
    • (2008) Eur. Respir. J , vol.31 , Issue.6 , pp. 1160-1166
    • Overbeek, M.J.1    Lankhaar, J.W.2    Westerhof, N.3
  • 12
    • 0033838125 scopus 로고    scopus 로고
    • Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
    • Deng Z, Morse JH, Slager SL et al. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am. J. Hum. Genet. 67(3), 737-744 (2000).
    • (2000) Am. J. Hum. Genet , vol.67 , Issue.3 , pp. 737-744
    • Deng, Z.1    Morse, J.H.2    Slager, S.L.3
  • 13
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. The International PPH Consortium
    • Lane KB, Machado RD, Pauciulo MW et al. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. The International PPH Consortium. Nat. Genet. 26(1), 81-84 (2000).
    • (2000) Nat. Genet , vol.26 , Issue.1 , pp. 81-84
    • Lane, K.B.1    Machado, R.D.2    Pauciulo, M.W.3
  • 14
    • 0346727461 scopus 로고    scopus 로고
    • Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis
    • Jimenez SA, Derk CT. Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis. Ann. Intern. Med. 140(1), 37-50 (2004).
    • (2004) Ann. Intern. Med , vol.140 , Issue.1 , pp. 37-50
    • Jimenez, S.A.1    Derk, C.T.2
  • 15
    • 0037785169 scopus 로고    scopus 로고
    • Systemic sclerosis: The susceptible host (genetics and environment)
    • Tan FK. Systemic sclerosis: the susceptible host (genetics and environment). Rheum. Dis. Clin. North Am. 29(2), 211-237 (2003).
    • (2003) Rheum. Dis. Clin. North Am , vol.29 , Issue.2 , pp. 211-237
    • Tan, F.K.1
  • 16
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
    • LeRoy EC, Black C, Fleischmajer R et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J. Rheumatol. 15(2), 202-205 (1988).
    • (1988) J. Rheumatol , vol.15 , Issue.2 , pp. 202-205
    • LeRoy, E.C.1    Black, C.2    Fleischmajer, R.3
  • 17
    • 0043074631 scopus 로고    scopus 로고
    • Mayes MD, Lacey JV Jr, Beebe-Dimmer J et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum. 48(8), 2246-2255 (2003).
    • Mayes MD, Lacey JV Jr, Beebe-Dimmer J et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum. 48(8), 2246-2255 (2003).
  • 18
    • 0038799783 scopus 로고    scopus 로고
    • Scleroderma epidemiology
    • Mayes MD. Scleroderma epidemiology. Rheum. Dis. Clin. North Am. 29(2), 239-254 (2003).
    • (2003) Rheum. Dis. Clin. North Am , vol.29 , Issue.2 , pp. 239-254
    • Mayes, M.D.1
  • 19
    • 0023784057 scopus 로고
    • An epidemiological study of scleroderma in the West Midlands
    • Silman A, Jannini S, Symmons D, Bacon P. An epidemiological study of scleroderma in the West Midlands. Br. J. Rheumatol. 27(4), 286-290 (1988).
    • (1988) Br. J. Rheumatol , vol.27 , Issue.4 , pp. 286-290
    • Silman, A.1    Jannini, S.2    Symmons, D.3    Bacon, P.4
  • 20
    • 0025936232 scopus 로고
    • Epidemiological study of patients with systemic sclerosis in Tokyo
    • Tamaki T, Mori S, Takehara K. Epidemiological study of patients with systemic sclerosis in Tokyo. Arch. Dermatol. Res. 283(6), 366-371 (1991).
    • (1991) Arch. Dermatol. Res , vol.283 , Issue.6 , pp. 366-371
    • Tamaki, T.1    Mori, S.2    Takehara, K.3
  • 22
    • 0026676156 scopus 로고
    • Echocardiographic evaluation of pulmonary arterial hypertension in patients with progressive systemic sclerosis and related syndromes
    • Murata I, Kihara H, Shinohara S, Ito K. Echocardiographic evaluation of pulmonary arterial hypertension in patients with progressive systemic sclerosis and related syndromes. Jpn. Circ. J. 56(10), 983-991 (1992).
    • (1992) Jpn. Circ. J , vol.56 , Issue.10 , pp. 983-991
    • Murata, I.1    Kihara, H.2    Shinohara, S.3    Ito, K.4
  • 23
    • 0030463427 scopus 로고    scopus 로고
    • Prevalence of pulmonary hypertension in limited and diffuse scleroderma
    • Battle RW, Davitt MA, Cooper SM et al. Prevalence of pulmonary hypertension in limited and diffuse scleroderma. Chest 110(6), 1515-1519 (1996).
    • (1996) Chest , vol.110 , Issue.6 , pp. 1515-1519
    • Battle, R.W.1    Davitt, M.A.2    Cooper, S.M.3
  • 24
    • 0347624457 scopus 로고    scopus 로고
    • Age and risk of pulmonary arterial hypertension in scleroderma
    • Schachna L, Wigley FM, Chang B, White B, Wise RA, Gelber AC. Age and risk of pulmonary arterial hypertension in scleroderma. Chest 124(6), 2098-2104 (2003).
    • (2003) Chest , vol.124 , Issue.6 , pp. 2098-2104
    • Schachna, L.1    Wigley, F.M.2    Chang, B.3    White, B.4    Wise, R.A.5    Gelber, A.C.6
  • 26
    • 0029920461 scopus 로고    scopus 로고
    • Isolated pulmonary hypertension in systemic sclerosis with diffuse cutaneous involvement: Association with serum anti-U3RNP antibody
    • Sacks DG, Okano Y, Steen VD, Curtiss E, Shapiro LS, Medsger TA Jr. Isolated pulmonary hypertension in systemic sclerosis with diffuse cutaneous involvement: association with serum anti-U3RNP antibody. J. Rheumatol. 23(4), 639-642 (1996).
    • (1996) J. Rheumatol , vol.23 , Issue.4 , pp. 639-642
    • Sacks, D.G.1    Okano, Y.2    Steen, V.D.3    Curtiss, E.4    Shapiro, L.S.5    Medsger Jr., T.A.6
  • 27
    • 0142187600 scopus 로고    scopus 로고
    • Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: Application of a registry approach
    • Mukerjee D, St George D, Coleiro B et al. Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach. Ann. Rheum. Dis. 62(11), 1088-1093 (2003).
    • (2003) Ann. Rheum. Dis , vol.62 , Issue.11 , pp. 1088-1093
    • Mukerjee, D.1    St George, D.2    Coleiro, B.3
  • 28
    • 29144536869 scopus 로고    scopus 로고
    • Early detection of pulmonary arterial hypertension in systemic sclerosis: A French nationwide prospective multicenter study
    • Hachulla E, Gressin V, Guillevin L et al. Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study. Arthritis Rheum. 52(12), 3792-3800 (2005).
    • (2005) Arthritis Rheum , vol.52 , Issue.12 , pp. 3792-3800
    • Hachulla, E.1    Gressin, V.2    Guillevin, L.3
  • 29
    • 0029985117 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic sclerosis: An analysis of 17 patients
    • Koh ET, Lee P, Gladman DD, Abu-Shakra M. Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients. Br. J. Rheumatol. 35(10), 989-993 (1996).
    • (1996) Br. J. Rheumatol , vol.35 , Issue.10 , pp. 989-993
    • Koh, E.T.1    Lee, P.2    Gladman, D.D.3    Abu-Shakra, M.4
  • 30
    • 34347266509 scopus 로고    scopus 로고
    • Changes in causes of death in systemic sclerosis, 1972-2002
    • Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972-2002. Ann. Rheum. Dis. 66(7), 940-944 (2007).
    • (2007) Ann. Rheum. Dis , vol.66 , Issue.7 , pp. 940-944
    • Steen, V.D.1    Medsger, T.A.2
  • 31
    • 0037126044 scopus 로고    scopus 로고
    • Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
    • McLaughlin VV, Shillington A, Rich S. Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation 106(12), 1477-1482 (2002).
    • (2002) Circulation , vol.106 , Issue.12 , pp. 1477-1482
    • McLaughlin, V.V.1    Shillington, A.2    Rich, S.3
  • 32
    • 32144461709 scopus 로고    scopus 로고
    • Natural history of mild-moderate pulmonary hypertension and the risk factors for severe pulmonary hypertension in scleroderma
    • Chang B, Schachna L, White B, Wigley FM, Wise RA. Natural history of mild-moderate pulmonary hypertension and the risk factors for severe pulmonary hypertension in scleroderma. J. Rheumatol. 33(2), 269-274 (2006).
    • (2006) J. Rheumatol , vol.33 , Issue.2 , pp. 269-274
    • Chang, B.1    Schachna, L.2    White, B.3    Wigley, F.M.4    Wise, R.A.5
  • 33
    • 0037331671 scopus 로고    scopus 로고
    • Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement
    • Steen V, Medsger TA Jr. Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum. 48(2), 516-522 (2003).
    • (2003) Arthritis Rheum , vol.48 , Issue.2 , pp. 516-522
    • Steen, V.1    Medsger Jr., T.A.2
  • 34
    • 38149040974 scopus 로고    scopus 로고
    • High N-terminal pro-brain natriuretic peptide levels and low diffusing capacity for carbon monoxide as independent predictors of the occurrence of precapillary pulmonary arterial hypertension in patients with systemic sclerosis
    • Allanore Y, Borderie D, Avouac J et al. High N-terminal pro-brain natriuretic peptide levels and low diffusing capacity for carbon monoxide as independent predictors of the occurrence of precapillary pulmonary arterial hypertension in patients with systemic sclerosis. Arthritis Rheum. 58(1), 284-291 (2008).
    • (2008) Arthritis Rheum , vol.58 , Issue.1 , pp. 284-291
    • Allanore, Y.1    Borderie, D.2    Avouac, J.3
  • 35
    • 33646113362 scopus 로고    scopus 로고
    • Right heart function in scleroderma: Insights from myocardial Doppler tissue imaging
    • Hsiao SH, Lee CY, Chang SM, Lin SK, Liu CP. Right heart function in scleroderma: insights from myocardial Doppler tissue imaging. J. Am. Soc. Echocardiogr. 19(5), 507-514 (2006).
    • (2006) J. Am. Soc. Echocardiogr , vol.19 , Issue.5 , pp. 507-514
    • Hsiao, S.H.1    Lee, C.Y.2    Chang, S.M.3    Lin, S.K.4    Liu, C.P.5
  • 36
    • 33846837374 scopus 로고    scopus 로고
    • Right heart function and scleroderma: Insights from tricuspid annular plane systolic excursion
    • Lee CY, Chang SM, Hsiao SH, Tseng JC, Lin SK, Liu CP. Right heart function and scleroderma: insights from tricuspid annular plane systolic excursion. Echocardiography 24(2), 118-125 (2007).
    • (2007) Echocardiography , vol.24 , Issue.2 , pp. 118-125
    • Lee, C.Y.1    Chang, S.M.2    Hsiao, S.H.3    Tseng, J.C.4    Lin, S.K.5    Liu, C.P.6
  • 37
    • 45349108255 scopus 로고    scopus 로고
    • Cardiac involvement in systemic sclerosis assessed by tissue-doppler echocardiography during routine care: A controlled study of 100 consecutive patients
    • Meune C, Avouac J, Wahbi K et al. Cardiac involvement in systemic sclerosis assessed by tissue-doppler echocardiography during routine care: a controlled study of 100 consecutive patients. Arthritis Rheum. 58(6), 1803-1809 (2008).
    • (2008) Arthritis Rheum , vol.58 , Issue.6 , pp. 1803-1809
    • Meune, C.1    Avouac, J.2    Wahbi, K.3
  • 38
    • 33745725935 scopus 로고    scopus 로고
    • Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma-associated pulmonary arterial hypertension
    • Williams MH, Handler CE, Akram R et al. Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma-associated pulmonary arterial hypertension. Eur. Heart J. 27(12), 1485-1494 (2006).
    • (2006) Eur. Heart J , vol.27 , Issue.12 , pp. 1485-1494
    • Williams, M.H.1    Handler, C.E.2    Akram, R.3
  • 39
    • 44949228252 scopus 로고    scopus 로고
    • Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension
    • Forfia PR, Mathai SC, Fisher MR et al. Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 177(12), 1364-1369 (2008).
    • (2008) Am. J. Respir. Crit. Care Med , vol.177 , Issue.12 , pp. 1364-1369
    • Forfia, P.R.1    Mathai, S.C.2    Fisher, M.R.3
  • 40
    • 33745637694 scopus 로고    scopus 로고
    • Systemic sclerosis associated pulmonary hypertension: Improved survival in the current era
    • Williams MH, Das C, Handler CE et al. Systemic sclerosis associated pulmonary hypertension: improved survival in the current era. Heart 92(7), 926-932 (2006).
    • (2006) Heart , vol.92 , Issue.7 , pp. 926-932
    • Williams, M.H.1    Das, C.2    Handler, C.E.3
  • 41
    • 0028597038 scopus 로고
    • Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin
    • Barst RJ, Rubin LJ, McGoon MD, Caldwell EJ, Long WA, Levy PS. Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin. Ann. Intern. Med. 121(6), 409-415 (1994).
    • (1994) Ann. Intern. Med , vol.121 , Issue.6 , pp. 409-415
    • Barst, R.J.1    Rubin, L.J.2    McGoon, M.D.3    Caldwell, E.J.4    Long, W.A.5    Levy, P.S.6
  • 42
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Rubin LJ, Badesch DB, Barst RJ et al. Bosentan therapy for pulmonary arterial hypertension. N. Engl. J. Med. 346(12), 896-903 (2002).
    • (2002) N. Engl. J. Med , vol.346 , Issue.12 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 43
    • 0034107636 scopus 로고    scopus 로고
    • Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing
    • Miyamoto S, Nagaya N, Satoh T et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. Am. J. Respir. Crit. Care Med. 161(2 Pt 1), 487-492 (2000).
    • (2000) Am. J. Respir. Crit. Care Med , vol.161 , Issue.2 PART 1 , pp. 487-492
    • Miyamoto, S.1    Nagaya, N.2    Satoh, T.3
  • 44
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group
    • Barst RJ, Rubin LJ, Long WA et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N. Engl. J. Med. 334(5), 296-302 (1996).
    • (1996) N. Engl. J. Med , vol.334 , Issue.5 , pp. 296-302
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 45
    • 0037151645 scopus 로고    scopus 로고
    • Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival
    • Sitbon O, Humbert M, Nunes H et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J. Am. Coll. Cardiol. 40(4), 780-788 (2002).
    • (2002) J. Am. Coll. Cardiol , vol.40 , Issue.4 , pp. 780-788
    • Sitbon, O.1    Humbert, M.2    Nunes, H.3
  • 46
    • 34249302372 scopus 로고    scopus 로고
    • A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology
    • Macchia A, Marchioli R, Marfisi R et al. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am. Heart J. 153(6), 1037-1047 (2007).
    • (2007) Am. Heart J , vol.153 , Issue.6 , pp. 1037-1047
    • Macchia, A.1    Marchioli, R.2    Marfisi, R.3
  • 47
    • 34249294002 scopus 로고    scopus 로고
    • The value of approved therapies for pulmonary arterial hypertension
    • Rich S. The value of approved therapies for pulmonary arterial hypertension. Am. Heart J. 153(6), 889-890 (2007).
    • (2007) Am. Heart J , vol.153 , Issue.6 , pp. 889-890
    • Rich, S.1
  • 48
    • 3042595558 scopus 로고    scopus 로고
    • End points in pulmonary arterial hypertension: The way forward
    • Peacock A, Naeije R, Galie N, Reeves JT. End points in pulmonary arterial hypertension: the way forward. Eur. Respir. J. 23(6), 947-953 (2004).
    • (2004) Eur. Respir. J , vol.23 , Issue.6 , pp. 947-953
    • Peacock, A.1    Naeije, R.2    Galie, N.3    Reeves, J.T.4
  • 49
    • 2942604605 scopus 로고    scopus 로고
    • End points and clinical trial designs in pulmonary arterial hypertension: Clinical and regulatory perspectives
    • Hoeper MM, Oudiz RJ, Peacock A et al. End points and clinical trial designs in pulmonary arterial hypertension: clinical and regulatory perspectives. J. Am. Coll. Cardiol. 43(12 Suppl. S), S48-S55 (2004).
    • (2004) J. Am. Coll. Cardiol , vol.43 , Issue.12 SUPPL. S
    • Hoeper, M.M.1    Oudiz, R.J.2    Peacock, A.3
  • 50
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333(4), 214-221 (1995).
    • (1995) N. Engl. J. Med , vol.333 , Issue.4 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 51
    • 0033032949 scopus 로고    scopus 로고
    • Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
    • Tuder RM, Cool CD, Geraci MW et al. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am. J. Respir. Crit. Care Med. 159(6), 1925-1932 (1999).
    • (1999) Am. J. Respir. Crit. Care Med , vol.159 , Issue.6 , pp. 1925-1932
    • Tuder, R.M.1    Cool, C.D.2    Geraci, M.W.3
  • 52
    • 0027324745 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
    • Giaid A, Yanagisawa M, Langleben D et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 328(24), 1732-1739 (1993).
    • (1993) N. Engl. J. Med , vol.328 , Issue.24 , pp. 1732-1739
    • Giaid, A.1    Yanagisawa, M.2    Langleben, D.3
  • 53
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S, Kaufmann E, Levy PS. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N. Engl. J. Med. 327(2), 76-81 (1992).
    • (1992) N. Engl. J. Med , vol.327 , Issue.2 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 54
    • 20544448927 scopus 로고    scopus 로고
    • Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
    • Sitbon O, Humbert M, Jais X et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111(23), 3105-3111 (2005).
    • (2005) Circulation , vol.111 , Issue.23 , pp. 3105-3111
    • Sitbon, O.1    Humbert, M.2    Jais, X.3
  • 55
    • 33646269035 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in France: Results from a national registry
    • Humbert M, Sitbon O, Chaouat A et al. Pulmonary arterial hypertension in France: results from a national registry. Am. J. Respir. Crit. Care Med. 173(9), 1023-1030 (2006).
    • (2006) Am. J. Respir. Crit. Care Med , vol.173 , Issue.9 , pp. 1023-1030
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3
  • 57
    • 33746379082 scopus 로고    scopus 로고
    • Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension
    • Sanchez O, Sitbon O, Jais X, Simonneau G, Humbert M. Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension.Chest 130(1), 182-189 (2006).
    • (2006) Chest , vol.130 , Issue.1 , pp. 182-189
    • Sanchez, O.1    Sitbon, O.2    Jais, X.3    Simonneau, G.4    Humbert, M.5
  • 58
    • 0025334367 scopus 로고
    • Regulatory functions of the vascular endothelium
    • Vane JR, Anggard EE, Botting RM. Regulatory functions of the vascular endothelium. N. Engl. J. Med. 323(1), 27-36 (1990).
    • (1990) N. Engl. J. Med , vol.323 , Issue.1 , pp. 27-36
    • Vane, J.R.1    Anggard, E.E.2    Botting, R.M.3
  • 59
    • 0032576672 scopus 로고    scopus 로고
    • Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension
    • McLaughlin VV, Genthner DE, Panella MM, Rich S. Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N. Engl. J. Med. 338(5), 273-277 (1998).
    • (1998) N. Engl. J. Med , vol.338 , Issue.5 , pp. 273-277
    • McLaughlin, V.V.1    Genthner, D.E.2    Panella, M.M.3    Rich, S.4
  • 60
    • 0025356811 scopus 로고
    • Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial
    • Rubin LJ, Mendoza J, Hood M et al. Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial. Ann. Intern. Med. 112(7), 485-491 (1990).
    • (1990) Ann. Intern. Med , vol.112 , Issue.7 , pp. 485-491
    • Rubin, L.J.1    Mendoza, J.2    Hood, M.3
  • 61
    • 0031031440 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Rubin LJ. Primary pulmonary hypertension. N. Engl. J. Med. 336(2), 111-117 (1997).
    • (1997) N. Engl. J. Med , vol.336 , Issue.2 , pp. 111-117
    • Rubin, L.J.1
  • 62
    • 0037086133 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial
    • Simonneau G, Barst RJ, Galie N et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am. J. Respir. Crit. Care Med. 165(6), 800-804 (2002).
    • (2002) Am. J. Respir. Crit. Care Med , vol.165 , Issue.6 , pp. 800-804
    • Simonneau, G.1    Barst, R.J.2    Galie, N.3
  • 63
    • 33645119109 scopus 로고    scopus 로고
    • Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: A prospective, multicenter, open-label, 12-week trial
    • Tapson VF, Gomberg-Maitland M, McLaughlin VV et al. Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial. Chest 129(3), 683-688 (2006).
    • (2006) Chest , vol.129 , Issue.3 , pp. 683-688
    • Tapson, V.F.1    Gomberg-Maitland, M.2    McLaughlin, V.V.3
  • 64
    • 0036875131 scopus 로고    scopus 로고
    • Emerging medical therapies for pulmonary arterial hypertension
    • Galie N, Manes A, Branzi A. Emerging medical therapies for pulmonary arterial hypertension. Prog. Cardiovasc. Dis. 45(3), 213-224 (2002).
    • (2002) Prog. Cardiovasc. Dis , vol.45 , Issue.3 , pp. 213-224
    • Galie, N.1    Manes, A.2    Branzi, A.3
  • 65
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
    • Badesch DB, Tapson VF, McGoon MD et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann. Intern. Med. 132(6), 425-434 (2000).
    • (2000) Ann. Intern. Med , vol.132 , Issue.6 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 66
    • 0032939165 scopus 로고    scopus 로고
    • Pulmonary edema during acute infusion of epoprostenol in a patient with pulmonary hypertension and limited scleroderma
    • Farber HW, Graven KK, Kokolski G, Korn JH. Pulmonary edema during acute infusion of epoprostenol in a patient with pulmonary hypertension and limited scleroderma. J. Rheumatol. 26(5), 1195-1196 (1999).
    • (1999) J. Rheumatol , vol.26 , Issue.5 , pp. 1195-1196
    • Farber, H.W.1    Graven, K.K.2    Kokolski, G.3    Korn, J.H.4
  • 67
    • 0031983972 scopus 로고    scopus 로고
    • Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease
    • Palmer SM, Robinson LJ, Wang A, Gossage JR, Bashore T, Tapson VF. Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease. Chest 113(1), 237-240 (1998).
    • (1998) Chest , vol.113 , Issue.1 , pp. 237-240
    • Palmer, S.M.1    Robinson, L.J.2    Wang, A.3    Gossage, J.R.4    Bashore, T.5    Tapson, V.F.6
  • 68
    • 34248389766 scopus 로고    scopus 로고
    • Fibrous remodeling of the pulmonary venous system in pulmonary arterial hypertension associated with connective tissue diseases
    • Dorfmuller P, Humbert M, Perros F et al. Fibrous remodeling of the pulmonary venous system in pulmonary arterial hypertension associated with connective tissue diseases. Hum. Pathol. 38(6), 893-902 (2007).
    • (2007) Hum. Pathol , vol.38 , Issue.6 , pp. 893-902
    • Dorfmuller, P.1    Humbert, M.2    Perros, F.3
  • 69
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomised placebo-controlled study
    • Channick RN, Simonneau G, Sitbon O et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 358(9288), 1119-1123 (2001).
    • (2001) Lancet , vol.358 , Issue.9288 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3
  • 70
    • 33750344748 scopus 로고    scopus 로고
    • Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: A subgroup analysis of the pivotal clinical trials and their open-label extensions
    • Denton CP, Humbert M, Rubin L, Black CM. Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions. Ann. Rheum. Dis. 65(10), 1336-1340 (2006).
    • (2006) Ann. Rheum. Dis , vol.65 , Issue.10 , pp. 1336-1340
    • Denton, C.P.1    Humbert, M.2    Rubin, L.3    Black, C.M.4
  • 71
    • 25844531004 scopus 로고    scopus 로고
    • Long-term outcome of bosentan treatment in primary pulmonary hypertension and pulmonary arterial hypertension associated with the scleroderma spectrum of diseases
    • Girgis R, Mathai SC, Krishnan JA, Wigley FM, Hassoun PM. Long-term outcome of bosentan treatment in primary pulmonary hypertension and pulmonary arterial hypertension associated with the scleroderma spectrum of diseases. J. Heart Lung Transplant. 24(10), 1626-1631 (2005).
    • (2005) J. Heart Lung Transplant , vol.24 , Issue.10 , pp. 1626-1631
    • Girgis, R.1    Mathai, S.C.2    Krishnan, J.A.3    Wigley, F.M.4    Hassoun, P.M.5
  • 72
    • 10744230817 scopus 로고    scopus 로고
    • Sitaxsentan therapy for pulmonary arterial hypertension
    • Barst RJ, Langleben D, Frost A et al. Sitaxsentan therapy for pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 169(4), 441-447 (2004).
    • (2004) Am. J. Respir. Crit. Care Med , vol.169 , Issue.4 , pp. 441-447
    • Barst, R.J.1    Langleben, D.2    Frost, A.3
  • 73
    • 34948865560 scopus 로고    scopus 로고
    • Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease
    • Girgis RE, Frost AE, Hill NS et al. Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease. Ann. Rheum. Dis. 66(11), 1467-1472 (2007).
    • (2007) Ann. Rheum. Dis , vol.66 , Issue.11 , pp. 1467-1472
    • Girgis, R.E.1    Frost, A.E.2    Hill, N.S.3
  • 74
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan for the treatment of pulmonary arterial hypertension: Results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2
    • Galie N, Olschewski H, Oudiz RJ et al. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. Circulation 117(23), 3010-3019 (2008).
    • (2008) Circulation , vol.117 , Issue.23 , pp. 3010-3019
    • Galie, N.1    Olschewski, H.2    Oudiz, R.J.3
  • 75
    • 36849073290 scopus 로고    scopus 로고
    • Sildenafil for pulmonary arterial hypertension associated with connective tissue disease
    • Badesch DB, Hill NS, Burgess G et al. Sildenafil for pulmonary arterial hypertension associated with connective tissue disease. J. Rheumatol. 34(12), 2417-2422 (2007).
    • (2007) J. Rheumatol , vol.34 , Issue.12 , pp. 2417-2422
    • Badesch, D.B.1    Hill, N.S.2    Burgess, G.3
  • 76
    • 20444501324 scopus 로고    scopus 로고
    • Lessons learned from cancer may help in the treatment of pulmonary hypertension
    • Adnot S. Lessons learned from cancer may help in the treatment of pulmonary hypertension. J. Clin. Invest. 115(6), 1461-1463 (2005).
    • (2005) J. Clin. Invest , vol.115 , Issue.6 , pp. 1461-1463
    • Adnot, S.1
  • 77
    • 26444540768 scopus 로고    scopus 로고
    • Reversal of experimental pulmonary hypertension by PDGF inhibition
    • Schermuly RT, Dony E, Ghofrani HA et al. Reversal of experimental pulmonary hypertension by PDGF inhibition. J. Clin. Invest. 115(10), 2811-2821 (2005).
    • (2005) J. Clin. Invest , vol.115 , Issue.10 , pp. 2811-2821
    • Schermuly, R.T.1    Dony, E.2    Ghofrani, H.A.3
  • 78
    • 40749109217 scopus 로고    scopus 로고
    • Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension
    • Moreno-Vinasco L, Gomberg-Maitland M, Maitland ML et al. Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension. Physiol. Genomics 33(2), 278-291 (2008).
    • (2008) Physiol. Genomics , vol.33 , Issue.2 , pp. 278-291
    • Moreno-Vinasco, L.1    Gomberg-Maitland, M.2    Maitland, M.L.3
  • 79
    • 25444484658 scopus 로고    scopus 로고
    • Imatinib for the treatment of pulmonary arterial hypertension
    • Ghofrani HA, Seeger W, Grimminger F. Imatinib for the treatment of pulmonary arterial hypertension. N. Engl. J. Med. 353(13), 1412-1413 (2005).
    • (2005) N. Engl. J. Med , vol.353 , Issue.13 , pp. 1412-1413
    • Ghofrani, H.A.1    Seeger, W.2    Grimminger, F.3
  • 80
    • 33746745449 scopus 로고    scopus 로고
    • Imatinib mesylate in the treatment of refractory idiopathic pulmonary arterial hypertension
    • Patterson KC, Weissmann A, Ahmadi T, Farber HW. Imatinib mesylate in the treatment of refractory idiopathic pulmonary arterial hypertension. Ann. Intern. Med. 145(2), 152-153 (2006).
    • (2006) Ann. Intern. Med , vol.145 , Issue.2 , pp. 152-153
    • Patterson, K.C.1    Weissmann, A.2    Ahmadi, T.3    Farber, H.W.4
  • 81
    • 33747041655 scopus 로고    scopus 로고
    • Long term imatinib treatment in pulmonary arterial hypertension
    • Souza R, Sitbon O, Parent F, Simonneau G, Humbert M. Long term imatinib treatment in pulmonary arterial hypertension. Thorax 61(8), 736 (2006).
    • (2006) Thorax , vol.61 , Issue.8 , pp. 736
    • Souza, R.1    Sitbon, O.2    Parent, F.3    Simonneau, G.4    Humbert, M.5
  • 82
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCRABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • Carroll M, Ohno-Jones S, Tamura S et al. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCRABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 90(12), 4947-4952 (1997).
    • (1997) Blood , vol.90 , Issue.12 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3
  • 83
    • 0033769794 scopus 로고    scopus 로고
    • Imbalance between platelet vascular endothelial growth factor and plateletderived growth factor in pulmonary hypertension. Effect of prostacyclin therapy
    • Eddahibi S, Humbert M, Sediame S et al. Imbalance between platelet vascular endothelial growth factor and plateletderived growth factor in pulmonary hypertension. Effect of prostacyclin therapy. Am. J. Respir. Crit. Care Med. 162(4 Pt 1), 1493-1499 (2000).
    • (2000) Am. J. Respir. Crit. Care Med , vol.162 , Issue.4 PART 1 , pp. 1493-1499
    • Eddahibi, S.1    Humbert, M.2    Sediame, S.3
  • 84
    • 40849083461 scopus 로고    scopus 로고
    • Grigoryev DN, Mathai SC, Fisher MR et al. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Transl. Res. 151(4), 197-207 (2008).
    • Grigoryev DN, Mathai SC, Fisher MR et al. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Transl. Res. 151(4), 197-207 (2008).
  • 85
    • 33845526777 scopus 로고    scopus 로고
    • Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
    • McLaughlin VV, Oudiz RJ, Frost A et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 174(11), 1257-1263 (2006).
    • (2006) Am. J. Respir. Crit. Care Med , vol.174 , Issue.11 , pp. 1257-1263
    • McLaughlin, V.V.1    Oudiz, R.J.2    Frost, A.3
  • 86
    • 33847368988 scopus 로고    scopus 로고
    • Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
    • Hoeper MM, Leuchte H, Halank M et al. Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur. Respir. J. 28(4), 691-694 (2006).
    • (2006) Eur. Respir. J , vol.28 , Issue.4 , pp. 691-694
    • Hoeper, M.M.1    Leuchte, H.2    Halank, M.3
  • 87
    • 54549125950 scopus 로고    scopus 로고
    • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
    • Simonneau G, Rubin LJ, Galie N et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann. Intern. Med. 149(8), 521-530 (2008).
    • (2008) Ann. Intern. Med , vol.149 , Issue.8 , pp. 521-530
    • Simonneau, G.1    Rubin, L.J.2    Galie, N.3
  • 88
    • 33847743922 scopus 로고    scopus 로고
    • Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension
    • Mathai SC, Girgis RE, Fisher MR et al. Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension. Eur. Respir. J. 29(3), 469-475 (2007).
    • (2007) Eur. Respir. J , vol.29 , Issue.3 , pp. 469-475
    • Mathai, S.C.1    Girgis, R.E.2    Fisher, M.R.3
  • 89
    • 10444246635 scopus 로고    scopus 로고
    • Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension
    • Hoeper MM, Faulenbach C, Golpon H, Winkler J, Welte T, Niedermeyer J. Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension. Eur. Respir. J. 24(6), 1007-1010 (2004).
    • (2004) Eur. Respir. J , vol.24 , Issue.6 , pp. 1007-1010
    • Hoeper, M.M.1    Faulenbach, C.2    Golpon, H.3    Winkler, J.4    Welte, T.5    Niedermeyer, J.6
  • 90
    • 0024449294 scopus 로고
    • Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry
    • Pietra GG, Edwards WD, Kay JM et al. Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry. Circulation 80(5), 1198-1206 (1989).
    • (1989) Circulation , vol.80 , Issue.5 , pp. 1198-1206
    • Pietra, G.G.1    Edwards, W.D.2    Kay, J.M.3
  • 91
    • 0021193273 scopus 로고
    • Primary pulmonary hypertension: Natural history and the importance of thrombosis
    • Fuster V, Steele PM, Edwards WD, Gersh BJ, McGoon MD, Frye RL. Primary pulmonary hypertension: natural history and the importance of thrombosis. Circulation 70(4), 580-587 (1984).
    • (1984) Circulation , vol.70 , Issue.4 , pp. 580-587
    • Fuster, V.1    Steele, P.M.2    Edwards, W.D.3    Gersh, B.J.4    McGoon, M.D.5    Frye, R.L.6
  • 92
    • 33845660778 scopus 로고    scopus 로고
    • Lung transplantation in scleroderma compared with idiopathic pulmonary fibrosis and idiopathic pulmonary arterial hypertension
    • Schachna L, Medsger TA Jr, Dauber JH et al. Lung transplantation in scleroderma compared with idiopathic pulmonary fibrosis and idiopathic pulmonary arterial hypertension. Arthritis Rheum. 54(12), 3954-3961 (2006).
    • (2006) Arthritis Rheum , vol.54 , Issue.12 , pp. 3954-3961
    • Schachna, L.1    Medsger Jr, T.A.2    Dauber, J.H.3


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