Isolated pulmonary hypertension in systemic sclerosis with diffuse cutaneous involvement: Association with serum anti-U3RNP antibody

Journal of Rheumatology

Volumn 23, Issue 4, 1996, Pages 639-642

  Sacks, Disa G ^b   Okano, Yutaka ^b   Steen, Virginia D ^b   Curtiss, Edward ^b   Shapiro, L Lee ^b   Medsger Jr , Thomas A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Pulmonary hypertension; Scleroderma; U3RNP antibody

Indexed keywords

AUTOANTIBODY; FIBRILLARIN;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SCHOOL CHILD; SYSTEMIC SCLEROSIS;

ADULT; AUTOANTIBODIES; CHROMOSOMAL PROTEINS, NON-HISTONE; FEMALE; HUMANS; HYPERTENSION, PULMONARY; MALE; PRECIPITIN TESTS; RETROSPECTIVE STUDIES; RIBONUCLEOPROTEINS; SCLERODERMA, SYSTEMIC; SKIN; SKIN DISEASES; SURVIVAL RATE;

EID: 0029920461     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Medsger TA Jr. Systemic sclerosis (scleroderma), localized forms of scleroderma and calcinosis. In: McCarty DJ, ed. Arthritis and Allied Conditions, 12th edition. Philadelphia: Lea and Febiger, 1992:1253-92.
2. Leroy EC, Black C, Fleischmajer R, et al: Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
3. Steen VD: Pulmonary involvement in systemic sclerosis. In: Cannon GW, Zimmerman GA, eds. The Lung In Rheumatic Disease New York: Marcel Deklcer, 1990:279-302.
4. Stupi AM, Steen VD, Medsger TA Jr, Owens G, Barnes EL. Rodnan GP. Pulmonary hypertension (PHT) in the CREST syndrome variant of progressive systemic sclerosis (PSS). Arthritis Rheum J 986:29:515-24
5. Medsger TA Jr, Steen VD, Ziegler GL, Rodnan GP: The natural history of skin involvement in progressive systemic sclerosis (PSS). Arthritis Rheum 1980;23:720-1.
6. Douvas AS, Achten M, Tan EM: Identification of a nuclear protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma. J Biol Chem 1979;254:10514-22.
7. Tan EM, Rodnan GP, Garcia I, Moroi Y, Fritzler MJ, Peebles C: Diversity of antinuclear antibodies in progressive systemic sclerosis: Anticentromere antibody and its relationship to CREST syndrome. Arthritis Rheum 1980;21:125-31.
8. Okano Y, Steen VD, Medsger TA Jr: Autoantibody reactive with RNA polymerase III in systemic sclerosis. Ann Intern Med 1993;119:1005-13.
9. Okano Y, Steen VD, Medsger TA Jr: Autoantibody to U3 nucleolar nbonucleoprotein (fibrillarin) in patients with systemic sclerosis. Arthritis Rheum 1992;35:95-100.
10. Salerni R, Rodnan GP, Leon DF, Shaver JA: Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (scleroderma). Ann Intern Med 1977;86:394-9
11. Steen VD, Graham G, Owens G, Medsger TA Jr: Isolated diffusing capacity reduction in systemic sclerosis. Arthritis Rheum 1992;35:765-70.
12. Steen VD, Conte C, Owens GR, Medsger TA Jr: Severe restrictive lung disease in systemic sclerosis. Arthritis Rheum 1994;37:1283-9