De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18)

Molecular Immunology

Volumn 41, Issue 12, 2004, Pages 1217-1224

  Bhakoo, Ashish ^a   Raynes, John G ^b   Heal, Jonathan R ^c   Keller, Michael ^d   Miller, Andrew D ^a,d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c Babraham Hall   (United Kingdom)

^d IC Vec Ltd   (United Kingdom)

Author keywords

Complementary peptides; Interleukin 18; Molecular recognition; Proteomic code

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ARGININE; CYTOKINE; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1BETA; PEPTIDE; RECEPTOR BLOCKING AGENT;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SOLUBILITY; X RAY ANALYSIS;

DRUG DESIGN; HUMANS; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; KINETICS; MOLECULAR MIMICRY; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-18; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 5144228627     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2004.05.011     Document Type: Article

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