-
1
-
-
39449110178
-
The immunology of multiple sclerosis
-
A thorough review of the evolving concepts of pathophysiology and immunology of MS
-
Bar-Or A. The immunology of multiple sclerosis. Semin Neurol 2008;28(1):29-45 •• A thorough review of the evolving concepts of pathophysiology and immunology of MS.
-
(2008)
Semin Neurol
, vol.28
, Issue.1
, pp. 29-45
-
-
Bar-Or, A.1
-
2
-
-
34548206670
-
Astrocytes-friends or foes in multiple sclerosis?
-
Williams A, Piaton G, Lubetzki C. Astrocytes-friends or foes in multiple sclerosis? Glia 2007;55(13):1300-1312
-
(2007)
Glia
, vol.55
, Issue.13
, pp. 1300-1312
-
-
Williams, A.1
Piaton, G.2
Lubetzki, C.3
-
3
-
-
34249781999
-
Pathogenesis of axonal and neuronal damage in multiple sclerosis
-
DOI 10.1212/01.wnl.0000275229.13012.32, PII 0000611420070529300005
-
Dutta R, Trapp BD. Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology 2007;68(22 Suppl 3):S22-31; discussion S43-54 (Pubitemid 46848608)
-
(2007)
Neurology
, vol.68
, Issue.22 SUPPL. 3
-
-
Dutta, R.1
Trapp, B.D.2
-
4
-
-
0037828315
-
Subpial demyelination in the cerebral cortex of multiple sclerosis patients
-
Bo L, Vedeler CA, Nyland HI, et al. Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J Neuropathol Exp Neurol 2003;62(7):723-732 (Pubitemid 36870458)
-
(2003)
Journal of Neuropathology and Experimental Neurology
, vol.62
, Issue.7
, pp. 723-732
-
-
Bo, L.1
Vedeler, C.A.2
Nyland, H.I.3
Trapp, B.D.4
Mork, S.J.5
-
5
-
-
34249700046
-
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
-
DOI 10.1093/brain/awm038
-
Magliozzi R, Howell O, Vora A, et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007;130(Pt 4):1089-1104 (Pubitemid 47355604)
-
(2007)
Brain
, vol.130
, Issue.4
, pp. 1089-1104
-
-
Magliozzi, R.1
Howell, O.2
Vora, A.3
Serafini, B.4
Nicholas, R.5
Puopolo, M.6
Reynolds, R.7
Aloisi, F.8
-
6
-
-
28744442319
-
Antigen-specific therapies in multiple sclerosis: Going beyond proteins and peptides
-
DOI 10.1080/08830180500379655
-
Fontoura P, Garren H, Steinman L. Antigen-specific therapies in multiple sclerosis: going beyond proteins and peptides. Int Rev Immunol 2005;24(5-6):415-446 (Pubitemid 41755155)
-
(2005)
International Reviews of Immunology
, vol.24
, Issue.5-6
, pp. 415-446
-
-
Fontoura, P.1
Garren, H.2
Steinman, L.3
-
7
-
-
47049096574
-
Autologous T-cell vaccination for multiple sclerosis: A perspective on progress
-
DOI 10.2165/00063030-200822040-00006
-
Vandenbark AA, Abulafia-Lapid R. Autologous T-cell vaccination for multiple sclerosis: a perspective on progress. BioDrugs 2008;22(4):265-273 •• A comprehensive review detailing the appeal and challenges of T-cell vaccine strategies in MS. (Pubitemid 351969834)
-
(2008)
BioDrugs
, vol.22
, Issue.4
, pp. 265-273
-
-
Vandenbark, A.A.1
Abulafia-Lapid, R.2
-
8
-
-
55349135951
-
Novel therapeutic strategies for multiple sclerosis-a multifaceted adversary
-
A fine review of novel therapies for MS that are currently under development
-
Lopez-Diego RS, Weiner HL. Novel therapeutic strategies for multiple sclerosis-a multifaceted adversary. Nat Rev Drug Discov 2008;7(11):909-925 • A fine review of novel therapies for MS that are currently under development.
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.11
, pp. 909-925
-
-
Lopez-Diego, R.S.1
Weiner, H.L.2
-
9
-
-
39049098224
-
Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes
-
DOI 10.1002/ana.21244
-
Banwell B, Bar-Or A, Cheung R, et al. Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes. Ann Neurol 2008;63(1):98-111 • An interesting article examining heightened T-cell reactivities in pediatric autoimmune diseases. (Pubitemid 351240556)
-
(2008)
Annals of Neurology
, vol.63
, Issue.1
, pp. 98-111
-
-
Banwell, B.1
Bar-Or, A.2
Cheung, R.3
Kennedy, J.4
Krupp, L.B.5
Becker, D.J.6
Dosch, H.-M.7
-
10
-
-
0021020031
-
Effect of treatment with copolymer 1 (Cop-1) on the in vivo and in vitro manifestations of experimental allergic encephalomyelitis (EAE)
-
Lisak RP, Zweiman B, Blanchard N, Rorke LB. Effect of treatment with Copolymer 1 (Cop-1) on the in vivo and in vitro manifestations of experimental allergic encephalomyelitis (EAE). J Neurol Sci 1983;62(1-3):281-293 (Pubitemid 14176255)
-
(1983)
Journal of the Neurological Sciences
, vol.62
, Issue.1-3
, pp. 281-293
-
-
Lisak, R.P.1
Zweiman, B.2
Blanchard, N.3
Rorke, L.B.4
-
11
-
-
0029082566
-
Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind placebo-controlled trial
-
The Copolymer 1 Multiple Sclerosis Study Group
-
Johnson KP, Brooks BR, Cohen JA, et al. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group. Neurology 1995;45(7):1268-1276
-
(1995)
Neurology
, vol.45
, Issue.7
, pp. 1268-1276
-
-
Johnson, K.P.1
Brooks, B.R.2
Cohen, J.A.3
-
12
-
-
0028340163
-
Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells-specificity and promiscuity
-
DOI 10.1073/pnas.91.11.4872
-
Fridkis-Hareli M, Teitelbaum D, Gurevich E, et al. Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells-specificity and promiscuity. Proc Natl Acad Sci USA 1994;91(11):4872-4876 (Pubitemid 24177752)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.11
, pp. 4872-4876
-
-
Fridkis-Hareli, M.1
Teitelbaum, D.2
Gurevich, E.3
Pecht, I.4
Brautbar, C.5
Oh Joong, K.6
Brenner, T.7
Arnon, R.8
Sela, M.9
-
13
-
-
34447299372
-
Glatiramer acetate in multiple sclerosis: A review
-
DOI 10.1111/j.1527-3458.2007.00010.x
-
Ruggieri M, Avolio C, Livrea P, Trojano M. Glatiramer acetate in multiple sclerosis: a review. CNS Drug Rev 2007 Summer;13(2):178-191 (Pubitemid 47052348)
-
(2007)
CNS Drug Reviews
, vol.13
, Issue.2
, pp. 178-191
-
-
Ruggieri, M.1
Avolio, C.2
Livrea, P.3
Trojano, M.4
-
14
-
-
0034041863
-
Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis
-
Duda PW, Schmied MC, Cook SL, et al. Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis. J Clin Invest 2000;105(7):967-976
-
(2000)
J Clin Invest
, vol.105
, Issue.7
, pp. 967-976
-
-
Duda, P.W.1
Schmied, M.C.2
Cook, S.L.3
-
15
-
-
0034255713
-
Characterization of T cell lines derived from glatiramer-acetate-treated multiple sclerosis patients
-
DOI 10.1016/S0165-5728(00)00263-0, PII S0165572800002630
-
Qin Y, Zhang DQ, Prat A, et al. Characterization of T cell lines derived from glatiramer-acetate-treated multiple sclerosis patients. J Neuroimmunol 2000;108(1-2):201-206 (Pubitemid 30438768)
-
(2000)
Journal of Neuroimmunology
, vol.108
, Issue.1-2
, pp. 201-206
-
-
Qin, Y.1
Zhang, D.Q.2
Prat, A.3
Pouly, S.4
Antel, J.5
-
16
-
-
54049086976
-
CD4+CD25+FoxP3+PD1- Regulatory T cells in acute and stable relapsing-remitting multiple sclerosis and their modulation by therapy
-
Saresella M, Marventano I, Longhi R, et al. CD4+CD25+FoxP3+PD1- regulatory T cells in acute and stable relapsing-remitting multiple sclerosis and their modulation by therapy. FASEB J 2008;22(10):3500-3508
-
(2008)
FASEB J
, vol.22
, Issue.10
, pp. 3500-3508
-
-
Saresella, M.1
Marventano, I.2
Longhi, R.3
-
17
-
-
18144387626
-
+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3
-
DOI 10.1073/pnas.0502187102
-
Hong J, Li N, Zhang X, et al. Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3. Proc Natl Acad Sci USA 2005;102(18):6449-6454 (Pubitemid 40617463)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.18
, pp. 6449-6454
-
-
Hong, J.1
Li, N.2
Zhang, X.3
Zheng, B.4
Zhang, J.Z.5
-
18
-
-
33646879037
-
+ T cells in multiple sclerosis
-
Tennakoon DK, Mehta RS, Ortega SB, et al. Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis. J Immunol 2006;176(11):7119-7129 (Pubitemid 43787894)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 7119-7129
-
-
Tennakoon, D.K.1
Mehta, R.S.2
Ortega, S.B.3
Bhoj, V.4
Racke, M.K.5
Karandikar, N.J.6
-
19
-
-
34548510355
-
+ regulatory T cells contribute to the therapeutic effects of glatiramer acetate in experimental autoimmune encephalomyelitis
-
DOI 10.1016/j.clim.2007.05.020, PII S1521661607012284
-
Jee Y, Piao WH, Liu R, et al. CD4(+) CD25(+) regulatory T cells contribute to the therapeutic effects of glatiramer acetate in experimental autoimmune encephalomyelitis. Clin Immunol 2007;125(1):34-42 (Pubitemid 47374537)
-
(2007)
Clinical Immunology
, vol.125
, Issue.1
, pp. 34-42
-
-
Jee, Y.1
Piao, W.H.2
Liu, R.3
Bai, X.F.4
Rhodes, S.5
Rodebaugh, R.6
Campagnolo, D.I.7
Shi, F.D.8
Vollmer, T.L.9
-
20
-
-
2442698974
-
Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis
-
Kim HJ, Ifergan I, Antel JP, et al. Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis. J Immunol 2004;172(11):7144-7153 (Pubitemid 38669158)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
, pp. 7144-7153
-
-
Kim, H.J.1
Ifergan, I.2
Antel, J.P.3
Seguin, R.4
Duddy, M.5
Lapierre, Y.6
Jalili, F.7
Bar-Or, A.8
-
21
-
-
2942594278
-
Multiple sclerosis: Glatiramer acetate inhibits monocyte reactivity in vitro and in vivo
-
DOI 10.1093/brain/awh163
-
Weber MS, Starck M, Wagenpfeil S, et al. Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo. Brain 2004;127(Pt 6):1370-1378 (Pubitemid 38745515)
-
(2004)
Brain
, vol.127
, Issue.6
, pp. 1370-1378
-
-
Weber, M.S.1
Starck, M.2
Wagenpfeil, S.3
Meinl, E.4
Hohlfeld, R.5
Farina, C.6
-
22
-
-
34547699396
-
Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
-
Weber MS, Prod'homme T, Youssef S, et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med 2007;13(8):935-943
-
(2007)
Nat Med
, vol.13
, Issue.8
, pp. 935-943
-
-
Weber, M.S.1
Prod'Homme, T.2
Youssef, S.3
-
23
-
-
1842685039
-
Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients
-
DOI 10.1016/j.clim.2004.01.004, PII S1521661604000154
-
Kim HJ, Biernacki K, Prat A, et al. Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients. Clin Immunol 2004;111(1):38-46 (Pubitemid 38482080)
-
(2004)
Clinical Immunology
, vol.111
, Issue.1
, pp. 38-46
-
-
Kim, H.J.1
Biernacki, K.2
Prat, A.3
Antel, J.P.4
Bar-Or, A.5
-
24
-
-
14544294320
-
Current issues in the treatment of human diseases by mucosal tolerance
-
Weiner HL. Current issues in the treatment of human diseases by mucosal tolerance. Ann NY Acad Sci 2004;1029:211-224
-
(2004)
Ann NY Acad Sci
, vol.1029
, pp. 211-224
-
-
Weiner, H.L.1
-
25
-
-
0027467440
-
Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis
-
Weiner HL, Mackin GA, Matsui M, et al. Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis. Science 1993;259(5099):1321-1324 (Pubitemid 23100270)
-
(1993)
Science
, vol.259
, Issue.5099
, pp. 1321-1324
-
-
Weiner, H.L.1
Mackin, G.A.2
Matsui, M.3
Orav, E.J.4
Khoury, S.J.5
Dawson, D.M.6
Hafler, D.A.7
-
26
-
-
0027298445
-
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
-
DOI 10.1038/363156a0
-
Sloan-Lancaster J, Evavold BD, Allen PM. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 1993;363(6425):156-159 (Pubitemid 23147012)
-
(1993)
Nature
, vol.363
, Issue.6425
, pp. 156-159
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
27
-
-
0030973661
-
Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms
-
DOI 10.1016/S0165-5728(96)00220-2, PII S0165572896002202
-
Gaur A, Boehme SA, Chalmers D, et al. Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms. J Neuroimmunol 1997;74(1-2):149-158 (Pubitemid 27128990)
-
(1997)
Journal of Neuroimmunology
, vol.74
, Issue.1-2
, pp. 149-158
-
-
Gaur, A.1
Boehme, S.A.2
Chalmers, D.3
Crowe, P.D.4
Pahuja, A.5
Ling, N.6
Brocke, S.7
Steinman, L.8
Conlon, P.J.9
-
28
-
-
0033791462
-
Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial
-
DOI 10.1038/80525
-
Kappos L, Comi G, Panitch H, et al. Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebocontrolled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group. Nat Med 2000;6(10):1176-1182 (Pubitemid 30792199)
-
(2000)
Nature Medicine
, vol.6
, Issue.10
, pp. 1176-1182
-
-
Kappos, L.1
Comi, G.2
Panitch, H.3
Oger, J.4
Antel, J.5
Conlon, P.6
Steinman, L.7
Comi, G.8
Kappos, L.9
Oger, J.10
Panitch, H.11
Rae-Grant, A.12
Castaldo, J.13
Eckert, N.14
Guarnaccia, J.B.15
Mills, P.16
Johnson, G.17
Calabresi, P.A.18
Pozzilli, C.19
Bastianello, S.20
Giugni, E.21
Witjas, T.22
Cozzone, P.23
Pelletier, J.24
Pohlau, D.25
Przuntek, H.26
Hoffmann, V.27
Bever Jr., C.28
Katz, E.29
Clanet, M.30
Berry, I.31
Brassat, D.32
Brunet, I.33
Edan, G.34
Duquette, P.35
Radue, E.-W.36
Schott, D.37
Lienert, C.38
Taksaoui, A.39
Rodegher, M.40
Filippi, M.41
Evans, A.42
Bourgouin, P.43
Zijdenbos, A.44
Salem, S.45
Ling, N.46
Alleva, D.47
Johnson, E.48
Gaur, A.49
Crowe, P.50
Liu, X.-J.51
more..
-
29
-
-
0036046080
-
Persistence of immune responses to altered and native myelin antigens in patients with multiple sclerosis treated with altered peptide ligand
-
DOI 10.1006/clim.2002.5258
-
Kim HJ, Antel JP, Duquette P, et al. Persistence of immune responses to altered and native myelin antigens in patients with multiple sclerosis treated with altered peptide ligand. Clin Immunol 2002;104(2):105-114 (Pubitemid 35026220)
-
(2002)
Clinical Immunology
, vol.104
, Issue.2
, pp. 105-114
-
-
Kim, H.J.1
Antel, J.P.2
Duquette, P.3
Alleva, D.G.4
Conlon, P.J.5
Bar-Or, A.6
-
30
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
DOI 10.1038/80516
-
Bielekova B, Goodwin B, Richert N, et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med 2000;6(10):1167-1175 (Pubitemid 30792198)
-
(2000)
Nature Medicine
, vol.6
, Issue.10
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
Cortese, I.4
Kondo, T.5
Afshar, G.6
Gran, B.7
Eaton, J.8
Antel, J.9
Frank, J.A.10
McFarland, H.F.11
Martin, R.12
-
31
-
-
0033762708
-
NBI-5788, an altered MBP83-99 peptide, induces a T-helper 2-like immune response in multiple sclerosis patients
-
DOI 10.1002/1531-8249(200011)48:5<758::AID-ANA9>3.0.CO;2-2
-
Crowe PD, Qin Y, Conlon PJ, Antel JP. NBI-5788, an altered MBP83-99 peptide, induces a T-helper 2-like immune response in multiple sclerosis patients. Ann Neurol 2000;48(5):758-765 (Pubitemid 30823226)
-
(2000)
Annals of Neurology
, vol.48
, Issue.5
, pp. 758-765
-
-
Crowe, P.D.1
Qin, Y.2
Conlon, P.J.3
Antel, J.P.4
-
32
-
-
0032735735
-
Presence of CpG DNA and the local cytokine milieu determine the efficacy of suppressive DNA vaccination in experimental autoimmune encephalomyelitis
-
Lobell A, Weissert R, Eltayeb S, et al. Presence of CpG DNA and the local cytokine milieu determine the efficacy of suppressive DNA vaccination in experimental autoimmune encephalomyelitis. J Immunol 1999;163(9):4754-4762 (Pubitemid 29501237)
-
(1999)
Journal of Immunology
, vol.163
, Issue.9
, pp. 4754-4762
-
-
Lobell, A.1
Weissert, R.2
Eltayeb, S.3
Svanholm, C.4
Olsson, T.5
Wigzell, H.6
-
33
-
-
34848865834
-
Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial
-
DOI 10.1001/archneur.64.10.nct70002
-
Bar-Or A, Vollmer T, Antel J, et al. Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. Arch Neurol 2007;64(10):1407-1415 (Pubitemid 47572664)
-
(2007)
Archives of Neurology
, vol.64
, Issue.10
, pp. 1407-1415
-
-
Bar-Or, A.1
Vollmer, T.2
Antel, J.3
Arnold, D.L.4
Bodner, C.A.5
Campagnolo, D.6
Gianettoni, J.7
Jalili, F.8
Kachuck, N.9
Lapierre, Y.10
Niino, M.11
Oger, J.12
Price, M.13
Rhodes, S.14
Robinson, W.H.15
Shi, F.-D.16
Utz, P.J.17
Valone, F.18
Weiner, L.19
Steinman, L.20
Garren, H.21
more..
-
34
-
-
44849103664
-
Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
-
The results of the Phase II MBP DNA vaccine clinical trial
-
Garren H, Robinson WH, Krasulova E, et al. Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis. Ann Neurol 2008;63(5):611-620 • The results of the Phase II MBP DNA vaccine clinical trial.
-
(2008)
Ann Neurol
, vol.63
, Issue.5
, pp. 611-620
-
-
Garren, H.1
Robinson, W.H.2
Krasulova, E.3
-
35
-
-
0030856261
-
96 in chronic progressive multiple sclerosis
-
DOI 10.1016/S0022-510X(97)00130-5, PII S0022510X97001305
-
Warren KG, Catz I, Wucherpfennig KW. Tolerance induction to myelin basic protein by intravenous synthetic peptides containing epitope P85 VVHFFKNIVTP96 in chronic progressive multiple sclerosis. J Neurol Sci 1997;152(1):31-38 (Pubitemid 27469708)
-
(1997)
Journal of the Neurological Sciences
, vol.152
, Issue.1
, pp. 31-38
-
-
Warren, K.G.1
Catz, I.2
Wucherpfennig, K.W.3
-
36
-
-
0033754799
-
Kinetic profiles of cerebrospinal fluid anti-MBP in response to intravenous MBP synthetic peptide DENP(85)VVHFFKNIVTP(96)RT in multiple sclerosis patients
-
Warren KG, Catz I. Kinetic profiles of cerebrospinal fluid anti-MBP in response to intravenous MBP synthetic peptide DENP(85)VVHFFKNIVTP(96)RT in multiple sclerosis patients. Mult Scler 2000;6(5):300-311
-
(2000)
Mult Scler
, vol.6
, Issue.5
, pp. 300-311
-
-
Warren, K.G.1
Catz, I.2
-
37
-
-
33746446276
-
Intravenous synthetic peptide MBP8298 delayed disease progression in an HLA Class II-defined cohort of patients with progressive multiple sclerosis: Results of a 24-month double-blind placebo-controlled clinical trial and 5 years of follow-up treatment
-
DOI 10.1111/j.1468-1331.2006.01533.x
-
Warren KG, Catz I, Ferenczi LZ, Krantz MJ. Intravenous synthetic peptide MBP8298 delayed disease progression in an HLA class II-defined cohort of patients with progressive multiple sclerosis: results of a 24-month double-blind placebo-controlled clinical trial and 5 years of follow-up treatment. Eur J Neurol 2006;13(8):887-895 (Pubitemid 44124687)
-
(2006)
European Journal of Neurology
, vol.13
, Issue.8
, pp. 887-895
-
-
Warren, K.G.1
Catz, I.2
Ferenczi, L.Z.3
Krantz, M.J.4
-
38
-
-
37149039794
-
Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis
-
An interesting article exploring trivalent T-cell receptor vaccine mechanisms
-
Vandenbark AA, Culbertson NE, Bartholomew RM, et al. Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis. Immunology 2008;123(1):66-78 • An interesting article exploring trivalent T-cell receptor vaccine mechanisms.
-
(2008)
Immunology
, vol.123
, Issue.1
, pp. 66-78
-
-
Vandenbark, A.A.1
Culbertson, N.E.2
Bartholomew, R.M.3
-
39
-
-
0019487117
-
Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein
-
DOI 10.1038/292060a0
-
Ben-Nun A, Wekerle H, Cohen IR. Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein. Nature 1981;292(5818):60-61 (Pubitemid 11048545)
-
(1981)
Nature
, vol.292
, Issue.5818
, pp. 60-61
-
-
Ben-Nun, A.1
Wekerle, H.2
Cohen, I.R.3
-
40
-
-
0034710361
-
T cell vaccination in secondary progressive multiple sclerosis
-
DOI 10.1016/S0165-5728(00)00235-6, PII S0165572800002356
-
Correale J, Lund B, McMillan M, et al. T cell vaccination in secondary progressive multiple sclerosis. J Neuroimmunol 2000;107(2):130-139 (Pubitemid 30347418)
-
(2000)
Journal of Neuroimmunology
, vol.107
, Issue.2
, pp. 130-139
-
-
Correale, J.1
Lund, B.2
McMillan, M.3
Ko, D.Y.4
McCarthy, K.5
Weiner, L.P.6
-
41
-
-
0036169323
-
T cell vaccination in multiple sclerosis: Results of a preliminary study
-
Zhang JZ, Rivera VM, Tejada-Simon MV, et al. T cell vaccination in multiple sclerosis: results of a preliminary study. J Neurol 2002;249(2):212-218 (Pubitemid 34143478)
-
(2002)
Journal of Neurology
, vol.249
, Issue.2
, pp. 212-218
-
-
Zhang, J.Z.1
Rivera, V.M.2
Tejada-Simon, M.V.3
Yang, D.4
Hong, J.5
Li, S.6
Haykal, H.7
Killian, J.8
Zang, Y.C.Q.9
-
42
-
-
0021080641
-
Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of myelin basic protein. Vaccination is determinant specific
-
Holoshitz J, Frenkel A, Ben-Nun A, Cohen IR. Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of myelin basic protein. Vaccination is determinant specific. J Immunol 1983;131(6):2810-2813 (Pubitemid 14208125)
-
(1983)
Journal of Immunology
, vol.131
, Issue.6
, pp. 2810-2813
-
-
Holoshitz, J.1
Frenkel, A.2
Ben Nun, A.3
Cohen, I.R.4
-
43
-
-
33747038380
-
Anti-ergotypic immunoregulation
-
Quintana FJ, Cohen IR. Anti-ergotypic immunoregulation. Scand J Immunol 2006;64(3):205-210
-
(2006)
Scand J Immunol
, vol.64
, Issue.3
, pp. 205-210
-
-
Quintana, F.J.1
Cohen, I.R.2
-
44
-
-
0034002679
-
Th2 immune regulation induced by T cell vaccination in patients with multiple sclerosis
-
DOI 10.1002/1521-4141(200003)30:3<908::AID-IMMU908>3.0.CO;2-1
-
Zang YC, Hong J, Tejada-Simon MV, et al. Th2 immune regulation induced by T cell vaccination in patients with multiple sclerosis. Eur J Immunol 2000;30(3):908-913 (Pubitemid 30216265)
-
(2000)
European Journal of Immunology
, vol.30
, Issue.3
, pp. 908-913
-
-
Zang, Y.C.Q.1
Hong, J.2
Tejada-Simon, M.V.3
Li, S.4
Rivera, V.M.5
Killian, J.M.6
Zhang, J.Z.7
-
45
-
-
63749125437
-
Autologous attenuated T-cell vaccine (Tovaxin (R)) dose escalation in multiple sclerosis relapsing-remitting and secondary progressive patients nonresponsive to approved immunomodulatory therapies
-
The most recent data evaluating the autologous attenuated T-cell vaccine in MS
-
Loftus B, Newsom B, Montgomery M, et al. Autologous attenuated T-cell vaccine (Tovaxin (R)) dose escalation in multiple sclerosis relapsing-remitting and secondary progressive patients nonresponsive to approved immunomodulatory therapies. Clin Immunol 2009;131(2):202-215 • The most recent data evaluating the autologous attenuated T-cell vaccine in MS.
-
(2009)
Clin Immunol
, vol.131
, Issue.2
, pp. 202-215
-
-
Loftus, B.1
Newsom, B.2
Montgomery, M.3
-
46
-
-
57349172905
-
Recombinant T cell receptor ligands: Immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis
-
A comprehensive review focusing on recombinant T-cell ligands
-
Offner H, Sinha S, Wang C, et al. Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis. Rev Neurosci 2008;19(4-5):327-339 •• A comprehensive review focusing on recombinant T-cell ligands.
-
(2008)
Rev Neurosci
, vol.19
, Issue.4-5
, pp. 327-339
-
-
Offner, H.1
Sinha, S.2
Wang, C.3
-
47
-
-
0043136755
-
Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation
-
Wang C, Mooney JL, Meza-Romero R, et al. Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation. J Immunol 2003;171(4):1934-1940 (Pubitemid 36966477)
-
(2003)
Journal of Immunology
, vol.171
, Issue.4
, pp. 1934-1940
-
-
Wang, C.1
Mooney, J.L.2
Meza-Romero, R.3
Chou, Y.K.4
Huan, J.5
Vandenbark, A.A.6
Offner, H.7
Burrows, G.G.8
-
48
-
-
36248944158
-
A promising therapeutic approach for multiple sclerosis: Recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS
-
DOI 10.1523/JNEUROSCI.3599-07.2007
-
Sinha S, Subramanian S, Proctor TM, et al. A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS. J Neurosci 2007;27(46):12531-12539 (Pubitemid 350127826)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.46
, pp. 12531-12539
-
-
Sinha, S.1
Subramanian, S.2
Proctor, T.M.3
Kaler, L.J.4
Grafe, M.5
Dahan, R.6
Huan, J.7
Vandenbark, A.A.8
Burrows, G.G.9
Offner, H.10
-
49
-
-
33748129891
-
Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE
-
DOI 10.1111/j.1471-4159.2006.04081.x
-
Wang C, Gold BG, Kaler LJ, et al. Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE. J Neurochem 2006;98(6):1817-1827 (Pubitemid 44313640)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.6
, pp. 1817-1827
-
-
Wang, C.1
Gold, B.G.2
Kaler, L.J.3
Yu, X.4
Afentoulis, M.E.5
Burrows, G.G.6
Vandenbark, A.A.7
Bourdette, D.N.8
Offner, H.9
-
50
-
-
34447109557
-
Bone marrow transplantation: Does it stop MS progression?
-
Freedman MS. Bone marrow transplantation: does it stop MS progression? J Neurol Sci 2007;259(1-2):85-89
-
(2007)
J Neurol Sci
, vol.259
, Issue.1-2
, pp. 85-89
-
-
Freedman, M.S.1
-
51
-
-
49949093283
-
Autologous haematopoietic stem-cell transplantation in multiple sclerosis
-
Mancardi G, Saccardi R. Autologous haematopoietic stem-cell transplantation in multiple sclerosis. Lancet Neurol 2008;7(7):626-636
-
(2008)
Lancet Neurol
, vol.7
, Issue.7
, pp. 626-636
-
-
Mancardi, G.1
Saccardi, R.2
-
52
-
-
33745875004
-
Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis
-
DOI 10.1212/01.wnl.0000219816.44094.f8, PII 0000611420060627000034
-
Chen JT, Collins DL, Atkins HL, et al. Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis. Neurology 2006;66(12):1935-1937 (Pubitemid 44049833)
-
(2006)
Neurology
, vol.66
, Issue.12
, pp. 1935-1937
-
-
Chen, J.T.1
Collins, D.L.2
Atkins, H.L.3
Freedman, M.S.4
Galal, A.5
Arnold, D.L.6
-
53
-
-
1642482932
-
Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation
-
Inglese M, Mancardi GL, Pagani E, et al. Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation. J Neurol Neurosurg Psychiatry 2004;75(4):643-644 (Pubitemid 38406670)
-
(2004)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.75
, Issue.4
, pp. 643-644
-
-
Inglese, M.1
Mancardi, G.L.2
Pagani, E.3
Rocca, M.A.4
Murialdo, A.5
Saccardi, R.6
Comi, G.7
Filippi, M.8
-
54
-
-
34249749383
-
Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis
-
DOI 10.1093/brain/awl370
-
Metz I, Lucchinetti CF, Openshaw H, et al. Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain 2007;130(Pt 5):1254-1262 (Pubitemid 47355940)
-
(2007)
Brain
, vol.130
, Issue.5
, pp. 1254-1262
-
-
Metz, I.1
Lucchinetti, C.F.2
Openshaw, H.3
Garcia-Merino, A.4
Lassmann, H.5
Freedman, M.S.6
Atkins, H.L.7
Azzarelli, B.8
Kolar, O.J.9
Bruck, W.10
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