Tolerance induction to myelin basic protein by intravenous synthetic peptides containing epitope P85 VVHFFKNIVTP96 in chronic progressive multiple sclerosis

Journal of the Neurological Sciences

Volumn 152, Issue 1, 1997, Pages 31-38

  Warren, K G ^a   Catz, I ^a   Wucherpfennig, K W ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

HLA DR2; MBP autoantibody; Multiple sclerosis; Peptide based tolerance

Indexed keywords

MYELIN BASIC PROTEIN;

ARTICLE; HUMAN; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; IMMUNOTHERAPY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0030856261     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(97)00130-5     Document Type: Article

References (30)

1. N.A. Mitchison Induction of immunological paralysis in two zones of dosage Proc. Roy. Soc. Lond. (Biol. Sci.) 161 1964 275 292
2. J.M. Critchfield M.K. Racke J.C. Zuniga-Pfluecker B. Cannella C.S. Raine J. Goverman M.J. Lenardo T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis Science 263 1994 1139 1143
3. M.J. Lenardo S. Boehme L. Chen B. Combadiere G. Fisher M. Freedman H. McFarland C. Pelfrey L. Zheng Autocrine feedback death and the regulation of mature T lymphocyte antigen responses Int. Rev. Immunol. 13 1995 115 134
4. R.S. Liblau C.I. Pearson K. Shokat R. Tisch X. Yang H.O. McDevitt High-dose soluble antigen: peripheral T cell proliferation or apoptosis Immunol. Rev. 142 1994 193 208
5. J.H. Russell C.L. White D.Y. Loh P. Meleedy-Rey Receptor-stimulated death pathway is opened by antigen in mature T cells Proc. Natl. Acad. Sci. USA 88 1991 2151 2155
6. L.G. Radvanyi G.B. Mills R.G. Miller Relegation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death J. Immunol. 150 1993 5704 5715
7. S.A. Boehme M.J. Lenardo Propriocidal apoptosis of mature T lymphocytes occurs at S phase in the cell cycle Eur. J. Immunol. 23 1993 1552 1560
8. L. Zheng G. Fisher R.E. Miller J. Peschon D.H. Lynch M.J. Lenardo Induction of apoptosis in mature T cells by tumour necrosis factor Nature 377 1995 348 351
9. H.K. Sytwu R.S. Liblau H.O. McDevitt The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice Immunity 5 1996 17 30
10. M.R. Alderson T.W. Tough T. Davis-Smith S. Braddy B. Falk K.A. Schooley R.G. Goodwin C.A. Smith F. Ramsdell D.H. Lynch Fas ligand mediates activation-induced cell death in human T lymphocytes J. Exp. Med. 181 1995 71 77
11. K.M. Shokat C.C. Goodnow Antigen-induced B-cell death and elimination during germinal-centre immune responses Nature 375 1995 334 338
12. B. Pulendran G. Kannourakis S. Nouri K.G.C. Smith G.J.V. Nossal Soluble antigen can cause enhanced apoptosis of germinal-centre B cells Nature 375 1995 331 334
13. T. Tsubata J. Wu T. Honjo B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T cell signal through CD4O Nature 364 1993 645 648
14. M.K. Racke J.M. Critchfield L. Quigley B. Cannella C.S. Raine H. McFarland M.J. Lenardo Intravenous antigen administration as a therapy for autoimmune demyelinating diseases Ann. Neurol. 39 1996 46 56
15. D. Elias T. Reshef O.S. Birk R. van der Zee M.D. Walker I.R. Cohen Vaccination against autoimmune mouse diabetes with a T cell epitope of the human 65-kDa heat shock protein Proc. Natl. Acad. Sci. USA 88 1991 3088 3091
16. M.A. Cremer A.D. Hernandez A.S. Townes J.M. Stuart A.H. Kang Collagen-induced arthritis in rats: antigen-specific suppression of arthritis and immunity by intravenously injected native type II collagen J. Immunol. 131 1983 2995 3000
17. A. Gaur B. Wiers A. Liu J. Rothbard C.G. Fathman Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy Science 258 1992 1491 1494
18. S. Brocke K. Gijbels M. Allegretta I. Ferber C. Piercy T. Blankenstein R. Martin U. Utz N. Karin D. Mitchell T. Veromaa A. Waisman A. Gaur P. Conlon N. Ling P.J. Fairchild D.C. Wraith A. O'Garra G. Fathman L. Steinman Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein Nature 379 1996 343 346
19. M. Pette K. Fujita D. Wilkinson D.M. Altmann J. Trowsdale G. Giegerich A. Hinkkanen J.T. Epplen L. Kappos H. Wekerle Myelin autoreactivity in multiple sclerosis: Recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple sclerosis patients and healthy donors Proc. Natl. Acad. Sci. USA 87 1990 7968 7972
20. K. Ota M. Matsui E.L. Milford G.A. Mackin H.L. Weiner D.A. Hafler T cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis Nature 346 1990 183 187
21. R. Martin D. Jaraquemada M. Flerlage J. Richert J. Whitaker E.O. Long D.E. McFarlin H.F. McFarland Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals J. Immunol. 145 1990 540 548
22. K.W. Wucherpfennig H.L. Weiner D.A. Hafler T cell recognition of myelin basic protein Immunol. Today 12 1991 277 282
23. K.W. Wucherpfennig A. Sette S. Southwood C. Oseroff M. Matsui J.L. Strominger D.A. Hafler Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones J. Exp. Med. 179 1994 279 290
24. K.G. Warren I. Catz Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid J. Neuroimmunol. 39 1992 81 90
25. K.G. Warren I. Catz Increased synthetic peptide specificity of tissue-CSF bound anti-MBP in multiple sclerosis J. Neuroimmunol. 43 1993 87 96
26. K.G. Warren I. Catz L. Steinman Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: The minimal B-cell epitope and a model of its features Proc. Natl. Acad. Sci. USA 92 1995 11061 11065
27. A. Valli A. Sette L. Kappos C. Oseroff J. Sidney G. Miescher M. Hochberger E.D. Albert L. Adorini Binding of myelin basic protein peptides to human histocompatibility leucocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients J. Clin. Invest. 91 1993 616 628
28. R. Martin M.D. Howell D. Jaraquemada M. Flerlage J. Richert S. Brostoff E.O. Long D.E. McFarlin H.F. McFarland A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis J. Exp. Med. 173 1991 19 24
29. K.G. Warren I. Catz Administration of myelin basic protein synthetic peptides to multiple sclerosis patients J. Neurol. Sci. 133 1995 85 94
30. C.P. Genain K. Abel N. Belmar F. Villinger D.P. Rosenberg C. Linington C.S. Raine S.L. Hauser Late complications of immune deviation therapy in a nonhuman primate Science 274 1996 2054 2057