Cerebellar activity and disturbed time sense after THC

Brain Research

Volumn 797, Issue 2, 1998, Pages 183-189

  Mathew, Roy J ^a   Wilson, William H ^a   G Turkington, Timothy ^a   Coleman, R Edward ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Anterior cingulate; Cerebellum; Cerebral blood flow; Cerebral metabolism; Positron emission tomography; Temporal disintegration; Tetrahydrocannabinol

Indexed keywords

CANNABIS; ILLICIT DRUG; TETRAHYDROCANNABINOL;

ADULT; ARTICLE; BEHAVIOR; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN METABOLISM; CEREBELLUM; CINGULATE GYRUS; DEPERSONALIZATION; DRUG ABUSE; FEMALE; HUMAN; HUMAN EXPERIMENT; INTOXICATION; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ADULT; CEREBELLUM; CEREBROVASCULAR CIRCULATION; FEMALE; GYRUS CINGULI; HALLUCINOGENS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; REGRESSION ANALYSIS; TETRAHYDROCANNABINOL; TIME PERCEPTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032578001     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00375-8     Document Type: Article

References (51)

1. Abood, Martin B.R. Neurobiology of marijuana abuse. Trends Neurosci. 13:1992;201-206.
2. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 3rd edn., American Psychiatric Association, Washington, DC, 1987.
3. Beck A.T., Beck R.W. Screening depressed patients in family practice. Postgrad. Med. 52:1972;81-85.
4. H. Brill, G.G. Nahas, Cannabis intoxication and mental illness, in: G.G. Nahas (Ed.), Marijuana: Science and Medicine, Raven Press, New York, 1984.
5. Byrum C.E., MacFall J.R., Charles H.C.et al. Accuracy and reproducibility of brain and tissue volumes using a magnetic resonance segmentation method. Psychiatry Res. Neuroimaging. 67:1996;215-234.
6. Clark L.D., Hughes R., Nakashima E.N. Behavioral effects of marijuana: experimental studies. Arch. Gen. Psychiatry. 23:1970;193-198.
7. Daum I., Ackermann N. Cerebellar contributions to cognition. Behav. Brain Res. 67:1995;201-210.
8. DeCarli C., Maisog J., Murphy D.G.M.et al. Method for quantification for brain, ventricular, and subarachnoid CSF volumes from MR images. J. Comput. Assisted Tomogr. 16(2):1992;274-284.
9. J. Dichgans, H. Diener, Clinical evidence for functional compartmentalization of the cerebellum, in: J. Bloedel, J. Dichgans, W. Precht (Eds.), Cerebellar Functions, Springer, Berlin, 1984, pp. 126-147.
10. Dixon J.C. Depersonalization phenomena in a sample population of college students. Br. J. Psychiatry. 9:1963;371-375.
11. Eichling J.O., Raichle M.E., Grubb R.L.et al. Evidence of the limitations of water as a freely diffusible tracer in brain of monkey. Circ. Res. 35:1974;358-364.
12. 15O and positron emission tomography: theory, procedure and normal values J. Comput. Assisted Tomogr. 4:1980;727-736.
13. Hallett B., Shahani R., Young R. EMG analysis of patients with cerebellar deficits. J. Neurol. Neurosurg. Psychiatry. 38:1975;1163-1169.
14. A.J. Harris, Harris Test of Lateral Dominance, Psychological Corporation, New York, 1974.
15. Hollister L.E. Cannabis - 1988. Acta Psychiatr. Scand. Suppl. 345:1988;108-118.
16. 15O -water J. Cereb. Blood Flow Metab. 3:1983;141-153.
17. Institute of Medicine, Marijuana and health, Report of a Study by a Committee of the Institute of Medicine, Division of Health Sciences Policy, National Academy Press, Washington, DC, 1982.
18. Ivry R.B. Cerebellar involvement in the explicit representation of temporal information. Ann. New York Acad. Sci. 682:1993;214-230.
19. Ivry R.B., Keele S.W. Timing functions of the cerebellum. J. Cogn. Neurosci. 1:1989;136-152.
20. Ivry R.B., Keele S.W., Diener H.C. Dissociation of the lateral and medium cerebellum in movement timing and movement execution. Exp. Brain Res. 73:1988;167-180.
21. Johnson B.A. Psychopharmacological effects of cannabis. Br. J. Hosp. Med. 43:1990;114-122.
22. Keele S.W., Ivry R.B. Does the cerebellum provide a common computation for diverse tasks: a timing hypothesis. Ann. New York Acad. Sci. 608:1991;179-211.
23. Mathew R.J., Wilson W.H. Acute changes in cerebral blood flow after smoking marijuana. Life Sci. 52:1993;757-767.
24. R.J. Mathew, W.H. Wilson, Depersonalization and cerebral blood flow, Presented at the Royal College of Psychiatrists Regional Meeting, Hyderabad, India, November 28 to December 1, 1996.
25. Mathew R.J., Wilson W.H., Tant S.R. Acute changes in cerebral blood flow associated with marijuana smoking. Acta Psychiatr. Scand. 79:1989;118-128.
26. Mathew R.J., Wilson W.H., Melges F.T. Temporal disintegration and its psychological and physiological correlates: changes in the experience of time after marijuana smoking. Ann. Clin. Psychiatry. 4:1992;235-245.
27. Mathew R.J., Wilson W.H., Humphreys D.F., Lowe J.V., Weithe K.E. Regional cerebral blood flow after marijuana smoking. J. Cereb. Blood Flow Metab. 12:1992;750-758.
28. Mathew R.J., Wilson W.H., Humphreys D.F., Lowe J.V., Weithe K.E. Changes in middle cerebral artery velocity after marijuana smoking. Biol. Psychiatry. 32:1992;164-169.
29. Mathew R.J., Wilson W.H., Humphreys D.F., Lowe J.V., Weithe K.E. Depersonalization after marijuana smoking. Biol. Psychiatry. 33:1993;431-441.
30. Mathew J., Wilson W.H., Coleman R.E., Turkington T.G., DeGrado T.R. Marijuana intoxication and brain activation in marijuana smokers. Life Sci. 60:1997;2075-2089.
31. D.M. McNair, M. Lorr, L.F. Doppleman, Manual for the Profile of Mood States, Educational and Industrial Testing Service, San Diego, 1971.
32. Melges F.T., Tinklenberg J.R., Hollister L.E., Gillespie H.K. Temporal disintegration and depersonalization during marijuana intoxication. Arch. Gen. Psychiatry. 23:1970;204-210.
33. Melges F.T., Tinklenberg J.R., Hollister L.E., Gillespie H.K. Marijuana and temporal disintegration. Science. 168:1970;118-120.
34. Melges F.T., Tinklenberg J.R., Hollister L.E., Gillespie H.K. Marijuana and the temporal span of awareness. Arch. Gen. Psychiatry. 24:1971;564-567.
35. Melges F.T., Tinklenberg J.R., Deardorff M., Davis M.H., Anderson R.E., Owen C.A. Temporal disorganization and delusional-like ideation. Arch. Gen. Psychiatry. 30:1974;855-861.
36. Perez-Reyes M., Timmons M.C., Lipton M.A., Davis K.H., Wall M.E. Intravenous injection in man of delta-9-tetrahydrocannabinol and 11-OH-delta-9-tetrahydrocannabinol. Science. 117:1972;633-634.
37. Raichle M.E., Grubb R.L., Gado M.H., Eichling J.O., Ter-Pogossian M.M. Correlations between regional cerebral blood flow and oxidative metabolism. Arch. Neurol. 33:1976;523-527.
38. Sasaki K., Gemba H. Compensatory motor function of the somatosensory cortex for dysfunction of the motor cortex following cerebellar hemispherectomy in the monkey. Exp. Brain Res. 56:1984;532-538.
39. Selzer M.L. The Michigan Alcoholism Screening Test: the quest for a new diagnostic instrument. AMJ Psychiatry. 127:1971;1653-1658.
40. Skinner H.A. The drug abuse screening test. Addict. Behav. 7:1983;363-371.
41. 11C deoxyglucose method for the measurement of local cerebral glucose utilization: the unconscious and anesthetized albino rat J. Neurochem. 28:1977;897-916.
42. C.D. Spielberger, R.L. Gorsuch, R.D. Lushene, STAI Manual, Consulting Psychologists Press, Palo Alto, CA, 1970.
43. Tinklenberg J.R., Kopell B.S., Melges F.T., Hollister L.E. Marijuana and alcohol: time production and memory functions. Arch. Gen. Psychiatry. 27:1972;812-815.
44. Tinklenberg J.R., Roth W.T., Kopell B.S. Marijuana and ethanol: differential effects on time perception, heart rate and subject response. Psychopharmacology. 49:1976;275-279.
45. Turkington T.G., Hoffman J.M., Jaszczak R.J.et al. Accuracy of surface fit registration for PET and MR brain images using full and incomplete brain surfaces. J. Comput. Assisted Tomogr. 19:1995;117-124.
46. Vachon L., Sulkowski A., Rich E. Marijuana effects on learning, attention and time estimation. Psychopharmacologia. 39:1974;1-11.
47. N.D. Volkow, J.S. Fowler, in: G.G. Nahas, C. Latour (Eds.), Cannabis; Physiopathology, Epidemiology, Detection, CRC Press, Boca Raton, FL, 1993.
48. 18F -2-fluoro-2-deoxyglucose Psychiatry Res. Neuroimaging. 40:1991;69-78.
49. N.D. Volkow, H. Gilllespie, N. Mullani, L. Tancredi, L. Hollister, M. Ivanovic, C. Grant, Use of positron emission tomography to investigate the action of marijuana in the human brain, in: G.G. Nahas, C. Latouri (Eds.), Orthophysiology of Illicit Drugs, Cannabis, Cocaine, Opiates, Pergamon, Oxford, 1991, pp. 3-12.
50. Volkow N.D., Gillespie H., Mullani N., Tancredi L., Grant C., Valentine A., Hollister L. Brain glucose metabolism in chronic marijuana users at baseline and during marijuana intoxication. Psychiatry Res. Neuroimaging. 67:1996;29-38.
51. Yesavage J.A., Leirer V.O., Denari M., Hollister L.E. Carry-over effects of marijuana Intoxication on aircraft pilot performance: a preliminary report. Am. J. Psychiatry. 142:1985;1325-1329.