The first pharmacophore model for potent NF-κB inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 19, 2009, Pages 5665-5669

  Tsai, Keng Chang ^a   Teng, Li Wei ^b,c   Shao, Yi Ming ^a   Chen, Yu Chen ^d   Lee, Yu Ching ^a   Li, Minyong ^e   Hsiao, Nai Wan ^b  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b NATIONAL CHANGHUA UNIVERSITY OF EDUCATION   (Taiwan)

^c Department Center For Biotechnology ^*  (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e SHANDONG UNIVERSITY   (China)

Author keywords

catalyst; NF B inhibitor; Pharmacophore; QSAR

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; PROTEIN;

ARTICLE; CATALYST; HYDROGEN BOND; HYDROPHOBICITY; PHARMACOPHORE; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; LIGANDS; MODELS, CHEMICAL; NF-KAPPA B; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE;

EID: 69949088308     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.08.021     Document Type: Article

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