Evaluation of mutagenicity and antimutagenicity of different fractions of Pterogyne nitens (Leguminosae), using Tradescantia pallida micronuclei assay;Avaliação de mutagenicidade e antimutagenicidade de diferentes frações de Pterogyne nitens (Leguminosae), utilizando ensaio de micronúcleo em Tradescantia pallida

Revista Brasileira de Farmacognosia

Volumn 19, Issue 1 A, 2009, Pages 61-67

  Ferreira, Fernanda G ^a   Regasini, Luis O ^a   De Oliveira, Aline M ^a   Campos, Juliana A D B ^a   Silva, Dulce H S ^a   Cavalheiro, Alberto J ^a   Dos Santos, Raquel A ^b   Bassi, Carmen L ^c   Bolzani, Vanderlan Da S ^a   Soares, Christiane P ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSIDADE FEDERAL DE MATO GROSSO   (Brazil)

Author keywords

Antimutagenicity; Leguminosae; Mutagenicity; Pterogyne nitens; Tradescantia pallida

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; ANTIMUTAGENIC AGENT; BUTANOL; PLANT EXTRACT; PTEROGYNE NITENS EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; LEGUME; MICRONUCLEUS; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; PLANT LEAF; PTEROGYNE NITENS; TRADESCANTIA; TRADESCANTIA PALLIDA;

EID: 69949086686     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2009000100014     Document Type: Article

References (36)

1. Batalha JRF, Guimarães ET, Lobo DJA, Lichtenfels AJFC, Deur T, Carvalho HA, Alves ES, Domingos M, Rodrigues GS, Saldiva PHN 1999. Exploring the clastogenic effects of air pollutants in São Paulo (Brazil) using the Tradescantia micronuclei assay. Mutat Res 426: 229-232. (Pubitemid 29234177)
2. Bolzani VS, Gunatilaka AAL, Kingston DGI 1995. Bioactive guanidine alkaloids from Pterogyne nitens. J Nat Prod 58: 1683-1688.
3. Bukart A 1952. Las Leguminosas Argentinas. Aemé Agengy, Buenos Aires.
4. Carvalho PER 1994. Espécies florestais brasileiras: recomendações silviculturais, potencialidades e uso da madeira, p. 163.
5. Carvalho-Oliveira R, Pozo RMK, Lobo DJA, Lichtenfels AJFC, Martins-Junior HÁ, Bustilho JOWV, Saiki M, Sato IM, Saldiva PHN, 2005. Diesel emissions significantly influence composition and mutagenicity of ambient particles: a case study in São Paulo, Brazil. Environ Res 98: 1-7. (Pubitemid 40254938)
6. Corral RA, Orazi OO, Petruccelli MF 1969. Guanidine alkaloids of Pterogyne nitens. Experientia 25: 1020-1021.
7. Costa MM, Hilliou F, Duarte P, Pereira LG, Almeida I, Leech M, Memelink J, Barcelo AR, Sottomayor M 2008. Molecular cloning and characterization of a vacuolar class III peroxidase involved in the metabolismo of anticancer alkaloids in Catharanthus roseus. Plant Physiol 146: 403-417. (Pubitemid 351230770)
8. Crivos M, Martinez MR, Pochettino ML, Remorini C, Sy A, Teves L 2007. Pathways as "signatures in landscape": Towards an ethnography of mobility among the Mbya-Guaraní (Northeastern Argentina). J Ethnobiol Ethnomed 3: 2. (Pubitemid 46979443)
9. Do Nascimento WMO, Cruz ED, Moraes MHD, Menten JOM 2006. Qualidade sanitária e germinação de sementes de Pterogyne nitens Tull. (Leguminosae- Caesalpinioideae). Rev Bras Sementes 28: 149-153.
10. Ferguson LR, Denny WA 2007. Genotoxicity of non-covalent interactions: DNA intercalators. Mutat Res 623: 14-23.
11. Fernandes DC, Regasini LO, Vellosa JCR, Pauletti PM, Castro-Gamboa I, Bolzani VS, Oliveira OMM, Silva DHS 2008. Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens. Chem Pharm Bull 56: 723-726. (Pubitemid 351669446)
12. Flores LER, Madrigal-Bujaidar E, Salazar M, Chamorr G 2003. Anticlastogenic effect of Spirulina maxima extract on the micronuclei induced by maleic hydrazide in Tradescantia. Life Sci 72: 1345-1351. (Pubitemid 36084380)
13. Havelka AM, Berndtsson M, Olofsson MH, Shoshan MC, Linder S 2007. Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect?. Mini Rev Med Chem 7: 1035-1039.
14. Hazen MJ, Gutiérrez-Gonzálvez MG 1988. UV-mediated toxic bioactivity of harmine in the meristematic cells of Allium cepa. Mutagenesis 3: 333-337.
15. Hochhauser D 1997. Modulation of chemical chemosensitivity through altered expression of cell cycle regulatory genes in cancer. Anticancer Drug 8: 903-910. (Pubitemid 28027088)
16. Kaya B, Creus A, Velazquez A, Yanikoglu A, Marcos R 2002. Genotoxicity is modulated by ascorbic acid: studies using the wing spot test in Drosophila. Mutat Res 520: 93-101. (Pubitemid 35247577)
17. Kaur K, Arora S, Kumar S, Nagpal A 2002. Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna. Food Chem Toxicol 40: 1475-1482.
18. Klumpp A, Ansel W, Fomim A, Schnirring S, Pickl C 2004. Influence of climatic condition the mutations in pollen mother cells of Tradescantia clone 4430 and implications for the Trad-MCN bioassay protocol. Hereditas 141: 142-148. (Pubitemid 39642663)
19. aed., Instituto Plantarum de Estudos da Flora, 01:163.
20. Ma TH 1983. Tradescantia micronucleus (Trad-MCN) test for environmental clastogens. In: Kolber, Wong, Dewoskin & Hughes (Eds.). In vitro toxicity testing of environmental agents. Plenium Publishing Cooporation, Macomb, 191-214.
21. Madle E, Obe G, Hansen J, Ristow H 1981. Harman and norharmane: induction of sister-chromatid exchanges in human peripheral lymphocytes in vitro and interaction with isolated DNA, Mutat Res 90: 433-442.
22. Nakayasy M, Nakasato F, Sakamoto H, Terada M, Sugimura T 1983. Mutagenic activity of norharman and Harman in Chinese lung cells in assay with diphtheria toxin resistance as a marker, Cancer Lett 17: 249-255. (Pubitemid 13194039)
23. Oliveira AM, Caliri CM, Regasini LO, Talascrea M, Peron MCC, Silva DHS, Santos AG, Bolzani VS, Cabalheiro AJ, Soares CP 2007. Evaluation of micronuclei frequency in Tradescantia pallida pollen mother cells treated with ethanolic extracts isolated from Cryptocarya mandioccana, Cryptocarya moschata and Pterogyne nitens, Rev Bras Toxicol 20: 73-78.
24. Paolini M, Abdel-Rahman SZ, Sapone A, Pedulli GF, Perocco P, Cantelli-Forti G, Legator MS 2003. Beta-carotene: a cancer chemopreventive agent or a co-carcinogen? Mutat Res 543: 195-200. (Pubitemid 36645079)
25. Roth I 1964. Microtecnica vegetal. Caracas: Imprenta Universitá ria, p. 88.
26. Santos RA, Cabral TR, Cabral IR, Antunes LMG, Andrade CP, Santos PCC, Bahia MO, Pessoa C, Nascimento JLM, Burbano RR, Takahashi CS 2008. Genotoxic effect of Physalis angulata L. (solanaceae) extract on human lymphocytes treated in vitro. Biocell 32: 195-200.
27. Sasaki YF, Yamada H, Shimoi K, Kinae N, Tomita I, Matsumura H, Ohta T, Shirasu Y 1992. Enhancing effects of heterocyclic amines and β-carbolines on the induction of chromosome aberrations in culture mammalian cells. Mutat Res 269: 79-95.
28. Schedler DJA, Baker DC 2004. Fluorinated cyclitols as useful biological probes of phosphatidyeinositol metabolism. Carbohyd Res 339: 1585-1595.
29. Sirikantaramas S, Asano T, Sudo H, Yamazaki M, Saito K 2007. Camptothecin: therapeutic potential and biotechnology. Curr Pharm Biotechnol 8: 196-202.
30. Snijman PW, Swanevelder S, Joubert E, Green IR, Gelderblom WCA 2007. The antimutagenic activity of the major flavonoids of rooibos (Aspalathus linearis): Some dose-response effects on mutagen activation- flavonoid interactions, Mutat Res 631: 111-123. (Pubitemid 46929154)
31. Valadares MC, Rezende KR, Pereira ERT, Sousa MC, Gonçalves B, Assis JC, Kato MJ 2007. Protective effects of 4-nerolidylcatechol agaist genotoxicity induced by cyclophosphamide. Food Chem Toxicol 45: 1975-1978. (Pubitemid 47238212)
32. Van Der Merwe JD, Joubert E, Richards ES, Manley M, Snijman PW, Marnewick JL, Gelderblom WCA 2006. A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp (honeybush) and Camellia sinensis teas. Mutat Res 611: 42-53. (Pubitemid 44780180)
33. Vucenik I, Shamsuddin AM 2003. Cancer Inhition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. J Nutr 133: 3778S-3784S. (Pubitemid 37392600)
34. Weber CJ 1930. A modification of Sakaguchi's reaction for the quantitative determination of arginine. J Biol Chem 86: 217-222.
35. Wheate NJ, Brodie CR, Collins JG, Kemp S, Aldrich-Wright JR 2007. DNA intercalators in cancer therapy: organic and inorganic drugs and their spectroscopic tools of analysis, Med Chem 7: 627-648. (Pubitemid 47099183)
36. Zeiger E 2003. Illusions of safety: antimutagens can be mutagens, and anticarcinogens can be carcinogens. Mutat Res 543: 191-194. (Pubitemid 36645078)