De novo synthesis of modified saxitoxins for sodium ion channel study

Journal of the American Chemical Society

Volumn 131, Issue 35, 2009, Pages 12524-12525

  Andresen, Brian M ^a   Du Bois, J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMOYL; CHANNEL PORE; CHEMICAL EQUATIONS; DE NOVO SYNTHESIS; ION CHANNEL; ION FLUXES; LIGAND-RECEPTOR; MOLECULAR ARCHITECTURE; PHOTOAFFINITY; SELECTIVE INHIBITORS; SODIUM ION CHANNELS;

BINDING ENERGY; CHEMICAL REACTIONS; METAL IONS;

BINDING SITES;

CARBAMIC ACID DERIVATIVE; CARBAMOYL; CARBON 13; LIGAND; SAXITOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING SITE; CARBAMOYLATION; CHEMICAL STRUCTURE; FEMALE; ION CURRENT; NONHUMAN; PHOTOAFFINITY LABELING; PROTEIN BINDING; PROTEIN FUNCTION; RECEPTOR AFFINITY; SYNTHESIS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; MODELS, MOLECULAR; POROSITY; PROTEIN CONFORMATION; RATS; SAXITOXIN; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 69849094291     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja904179f     Document Type: Article

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