Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to complete in vivo biotransformation characterization: Demonstration with buspirone metabolite identification

Rapid Communications in Mass Spectrometry

Volumn 23, Issue 18, 2009, Pages 3003-3012

  Li, Austin C ^a,b   Ding, Jie ^a   Jiang, Xiangyu ^a   Denissen, Jon ^a  

^a 206 Carnegie Center   (United States)

^b CEPHALON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOMOLECULES; DATA ACQUISITION; DATA MINING; EXTRACTION; HYDROXYLATION; IONS; KNOWLEDGE BASED SYSTEMS; LIQUID CHROMATOGRAPHY; MATRIX ALGEBRA; OXIDATION; PARAFFINS;

HUMAN LIVER MICROSOMES; IN-VIVO; ION EXTRACTION; ION SCAN; LTQ ORBITRAP; MATRIX; METABOLITE IDENTIFICATION; N-DEALKYLATION; PRODUCT IONS; WORK-FLOWS;

METABOLITES;

EID: 69849089067     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.4207     Document Type: Article

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