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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 27, 2009, Pages 2989-2995

Simultaneous determination of OZ277, a synthetic 1,2,4-trioxolane antimalarial, and its polar metabolites in rat plasma using hydrophilic interaction chromatography

(5) Bhamidipati, Ravi K a Morizzi, Julia a Chiu, Francis C K a Shackleford, David M a Charman, Susan A a

a MONASH UNIVERSITY (Australia)

Author keywords

1,2,4 trioxolane; HILIC MS; OZ277; Rat plasma; RBx11160

Indexed keywords

BIOMOLECULES; BODY FLUIDS; ELECTROSPRAY IONIZATION; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PRECIPITATION (CHEMICAL); SILICA;

1,2,4-TRIOXOLANE; HILIC/MS; OZ277; RAT PLASMA; RBX11160;

RATS;

ACETONITRILE; ANTIMALARIAL AGENT; DRUG METABOLITE; OZ 277; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; STORAGE; VALIDATION STUDY;

RATTUS;

EID: 69749120711 PISSN: 15700232 EISSN: None Source Type: Journal
DOI: 10.1016/j.jchromb.2009.07.015 Document Type: Article

Times cited : (9)

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