Mitochondrial and sarcoplasmic protein changes in hearts from copper-deficient rats: up-regulation of PGC-1α transcript and protein as a cause for mitochondrial biogenesis in copper deficiency

Journal of Nutritional Biochemistry

Volumn 20, Issue 10, 2009, Pages 823-830

  Medeiros, Denis M ^a   Jiang, Yu ^a   Klaahsen, Darcey ^a   Lin, Dingbo ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Copper deficiency; Metabolic enzymes; PGC 1 ; Proteinomics; Rats

Indexed keywords

ACONITATE HYDRATASE 2; ALDEHYDE REDUCTASE 1; ALPHA CRYSTALLIN; BETA ENOLASE 3; CARBONATE DEHYDRATASE II; COPPER; CREATINE KINASE MM; DIHYDROLIPOAMIDE DEHYDROGENASE; GLUCOSE REGULATED PROTEIN 75; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN ALPHA; ISOCITRATE DEHYDROGENASE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MITOCHONDRIAL PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PHOSPHOFRUCTOSE KINASE; PREALBUMIN; PREPROAPOLIPOPROTEIN A1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TRANSFERRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COPPER DEFICIENCY; DOWN REGULATION; ENERGY METABOLISM; FATTY ACID OXIDATION; GLUCONEOGENESIS; GLYCOLYSIS; HEART MUSCLE METABOLISM; HEART VENTRICLE HYPERTROPHY; HEMATOCRIT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; COPPER; DNA PRIMERS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; MALE; MITOCHONDRIA, HEART; MUSCLE PROTEINS; POLYMERASE CHAIN REACTION; RATS; RATS, LONG-EVANS; RNA, MESSENGER; RNA-BINDING PROTEINS; SARCOPLASMIC RETICULUM; TRANSCRIPTION FACTORS; UP-REGULATION;

RATTUS;

EID: 69749107576     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.08.001     Document Type: Article

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