CK2 negatively regulates Gαs signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 33, 2009, Pages 14096-14101

  Rebholz, Heike ^a   Nishi, Akinori ^b   Liebscher, Sabine ^a   Nairn, Angus C ^c   Flajolet, Marc ^a   Greengard, Paul ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine A2A receptor; Casein kinase 2; Dopamine 1 receptor; GPCR; Striatum

Indexed keywords

ADENOSINE A2A RECEPTOR; CASEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR;

ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; RNA INTERFERENCE;

ANIMALS; APIGENIN; BRAIN; CASEIN KINASE II; CELL LINE; CELL LINE, TUMOR; CYCLIC AMP; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS; HUMANS; KINETICS; MICE; MODELS, BIOLOGICAL; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 69549083221     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906857106     Document Type: Article

References (39)

1. Alexander SP, Mathie A, Peters JA (2005) Guide to receptors and channels, 1st edition (2005 revision). Br J Pharmacol 144:S1-S128. (Pubitemid 44289011)
2. Premont RT, Gainetdinov RR (2007) Physiological roles of G protein-coupled receptor kinases and arrestins. Annu Rev Physiol 69:511-534.
3. Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacol Rev 53:1-24.
4. Budd DC, Willars GB, McDonald JE, Tobin AB (2001) Phosphorylation of the Gq/11-coupled m3-muscarinic receptor is involved in receptor activation of the ERK-1/2 mitogen-activated protein kinase pathway. J Biol Chem 276:4581-4587. (Pubitemid 37371338)
5. Greengard P (2001) The neurobiology of slow synaptic transmission. Science 294:1024-1030.
6. Gerfen CR (2003) D1 dopamine receptor supersensitivity in the dopamine-depleted striatum animal model of Parkinson's disease. Neuroscientist 9:455-462.
7. Sidhu A, Fishman PH (1990) Identification and characterization of functional D1 dopamine receptors in a human neuroblastoma cell line. Biochem Biophys Res Commun 166:574-579. (Pubitemid 20049882)
8. Kimura K, White BH, Sidhu A (1995) Coupling of human D-1 dopamine receptors to different guanine nucleotide binding proteins. Evidence that D-1 dopamine receptors can couple to both Gs and G(o). J Biol Chem 270:14672-14678.
9. Pagano MA, et al. (2004) 2-Dimethylamino-4,5,6,7-tetrabromo-1H- benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2. Biochem Biophys Res Commun 321:1040-1044. (Pubitemid 39044414)
10. Stipanovich A, et al. (2008) A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature 453:879-884. (Pubitemid 351832565)
11. Girault JA, Hemmings HC, Jr, Zorn SH, Gustafson EL, Greengard P (1990) Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II. J Neurochem 55:1772-1783. (Pubitemid 20351110)
12. Singh TJ, Huang KP (1985) Glycogen synthase (casein) kinase-1: Tissue distribution and subcellular localization. FEBS Lett 190:84-88. (Pubitemid 16251325)
13. Herve D, et al. (1993) G(olf) and Gs in rat basal ganglia: Possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase. J Neurosci 13:2237-2248.
14. Greene JG (2006) Gene expression profiles of brain dopamine neurons and relevance to neuropsychiatric disease. J Physiol 575:411-416.
15. Tateyama M, Kubo Y (2006) Dual signaling is differentially activated by different active states of the metabotropic glutamate receptor 1alpha. Proc Natl Acad Sci USA 103:1124-1128. (Pubitemid 43212232)
16. Torrecilla I, et al. (2007) Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2. J Cell Biol 177:127-137. (Pubitemid 46588407)
17. Hanyaloglu AC, et al. (2001) Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to beta-arrestin-dependent internalization. J Biol Chem 276:18066-18074. (Pubitemid 37411371)
18. Gaudreau R, Le Gouill C, Venne MH, Stankova J, Rola-Pleszczynski M (2002) Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization. J Biol Chem 277:31567-31576. (Pubitemid 34968959)
19. Niefind K, Guerra B, Ermakowa I, Issinger OG (2001) Crystal structure of human protein kinase CK2: Insights into basic properties of the CK2 holoenzyme. EMBO J 20:5320-5331. (Pubitemid 32959451)
20. Kusk M, Bendixen C, Duno M, Westergaard O, Thomsen B (1995) Genetic dissection of intersubunit contacts within human protein kinase CK2. J Mol Biol 253:703-711.
21. Meggio F, Brunati AM, Pinna LA (1987) Polycation-dependent, Ca2+-antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase FEBS Lett 215:241-246.
22. Quelo I, Gauthier C, St-Arnaud R (2005) Casein kinase II phosphorylation regulates alphaNAC subcellular localization and transcriptional coactivating activity. Gene Expr 12:151-163. (Pubitemid 41186015)
23. Vickery RG, von Zastrow M (1999) Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. J Cell Biol 144:31-43.
24. Raman C, Kuo A, Deshane J, Litchfield DW, Kimberly RP (1998) Regulation of casein kinase 2 by direct interaction with cell surface receptor CD5. J Biol Chem 273:19183-19189. (Pubitemid 28366316)
25. Poletto G, et al. (2008) The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide. Biochemistry 47:8317-8325.
26. Lin FT, et al. (2002) Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors. Biochemistry 41:10692-10699.
27. Kim YM, Barak LS, Caron MG, Benovic JL (2002) Regulation of arrestin-3 phosphorylation by casein kinase II. J Biol Chem 277:16837-16846. (Pubitemid 34967707)
28. Svenningsson P, et al. (2000) Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proc Natl Acad Sci USA 97:1856-1860. (Pubitemid 30118533)
29. Chung HJ, Huang YH, Lau LF, Huganir RL (2004) Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand. J Neurosci 24:10248-10259.
30. Greenwood JA, Scott CW, Spreen RC, Caputo CB, Johnson GV (1994) Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert. Identification of threonine 39 as the primary phosphate acceptor. J Biol Chem 269:4373-4380. (Pubitemid 24237803)
31. Wong EV, Schaefer AW, Landreth G, Lemmon V (1996) Casein kinase II phosphorylates the neural cell adhesion molecule L1. J Neurochem 66:779-786. (Pubitemid 26036710)
32. Lin JM, et al. (2002) A role for casein kinase 2alpha in the Drosophila circadian clock. Nature 420:816-820. (Pubitemid 36019629)
33. Ryu MY, et al. (2008) Localization of CKII beta subunits in Lewy bodies of Parkinson's disease. J Neurol Sci 266:9-12.
34. Lee G, et al. (2004) Casein kinase II-mediated phosphorylation regulates alphasynuclein/synphilin-1 interaction and inclusion body formation. J Biol Chem 279:6834-6839. (Pubitemid 38248825)
35. Okochi M, et al. (2000) Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein. J Biol Chem 275:390-397. (Pubitemid 30038997)
36. Loerch PM, et al. (2008) Evolution of the aging brain transcriptome and synaptic regulation. PLoS ONE 3:e3329.
37. Blanquet PR (2000) Casein kinase 2 as a potentially important enzyme in the nervous system. Prog Neurobiol 60:211-246.
38. Flajolet M, et al. (2003) Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3. Proc Natl Acad Sci USA 100:16006-16011. (Pubitemid 38021105)
39. Nishi A, et al. (2000) Amplification of dopaminergic signaling by a positive feedback loop. Proc Natl Acad Sci USA 97:12840-12845. (Pubitemid 30840503)