Does dietary DHA improve neural function in children? Observations in phenylketonuria

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 81, Issue 2-3, 2009, Pages 159-164

  Koletzko, Berthold ^a   Beblo, Skadi ^a   Demmelmair, Hans ^a   Müller Felber, Wolfgang ^a   Hanebutt, Fabienne L ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID; ICOSAPENTAENOIC ACID; PHENYLALANINE; PHOSPHOLIPID;

AGE; ARTICLE; BLOOD ANALYSIS; CHILD; CHILD HEALTH; CHILD NUTRITION; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENERGY METABOLISM; EVOKED VISUAL RESPONSE; FATTY ACID METABOLISM; FEMALE; HUMAN; LATENT PERIOD; MALE; MOTOR COORDINATION; NERVOUS SYSTEM FUNCTION; OMNIVORE; PHENYLKETONURIA; PRESCHOOL CHILD; PRIORITY JOURNAL; RATING SCALE; SCHOOL CHILD; TREATMENT OUTCOME;

CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; EVOKED POTENTIALS, VISUAL; FEMALE; FISH OILS; HUMANS; MALE; MOTOR SKILLS; PHENYLKETONURIAS; PHOSPHOLIPIDS;

EID: 69449101503     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2009.06.006     Document Type: Article

References (44)

1. Clandinin M.T., Jumpsen J., and Suh M. Relationship between fatty acid accretion, membrane composition, and biologic functions. J. Pediatr. 125 (1994) S25-S32
2. Sellmayer A., and Koletzko B. Long-chain polyunsaturated fatty acids and eicosanoids in infants-physiological and pathophysiological aspects and open questions. Lipids 34 (1999) 199-205
3. Salem Jr. N., Litman B., Kim H.Y., and Gawrisch K. Mechanisms of action of docosahexaenoic acid in the nervous system. Lipids 36 (2001) 945-959
4. Cetin I., and Koletzko B. Long-chain omega-3 fatty acid supply in pregnancy and lactation. Curr. Opin. Clin. Nutr. Metab. Care 11 (2008) 297-302
5. Crawford M.A., Costeloe K., Ghebremeskel K., Phylactos A., Skirvin L., and Stacey F. Are deficits of arachidonic and docosahexaenoic acids responsible for the neural and vascular complications of preterm babies?. Am. J. Clin. Nutr. 66 (1997) 1032S-1041S
6. Calder P.C. Fatty acids and gene expression related to inflammation. Nestle Nutr Workshop Ser Clin Perform Programme 7 (2002) 19-36 discussion 36-40
7. Sprecher H. Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim. Biophys. Acta 1486 (2000) 219-231
8. Sauerwald T.U., Hachey D.L., Jensen C.L., and Heird W.C. New insights into the metabolism of long chain polyunsaturated fatty acids during infancy. Eur. J. Med. Res. 2 (1997) 88-92
9. Nakamura M.T., Cho H.P., Xu J., Tang Z., and Clarke S.D. Metabolism and functions of highly unsaturated fatty acids: an update. Lipids 36 (2001) 961-964
10. Burdge G.C., and Calder P.C. Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod. Nutr. Dev. 45 (2005) 581-597
11. Rosell M.S., Lloyd-Wright Z., Appleby P.N., Sanders T.A., Allen N.E., and Key T.J. Long-chain n-3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan men. Am. J. Clin. Nutr. 82 (2005) 327-334
12. Koletzko B., Rodriguez-Palmero M., Demmelmair H., Fidler N., Jensen R., and Sauerwald T. Physiological aspects of human milk lipids. Early Hum. Dev. 65 (2001) S3-S18
13. Brenna J.T., Varamini B., Jensen R.G., Diersen-Schade D.A., Boettcher J.A., and Arterburn L.M. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am. J. Clin. Nutr. 85 (2007) 1457-1464
14. Geppert J., Kraft V., Demmelmair H., and Koletzko B. Docosahexaenoic acid supplementation in vegetarians effectively increases omega-3 index: a randomized trial. Lipids 40 (2005) 807-814
15. Harris W.S., Pottala J.V., Sands S.A., and Jones P.G. Comparison of the effects of fish and fish-oil capsules on the n 3 fatty acid content of blood cells and plasma phospholipids. Am. J. Clin. Nutr. 86 (2007) 1621-1625
16. Schaeffer L., Gohlke H., Muller M., et al. Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum. Mol. Genet. 15 (2006) 1745-1756
17. Koletzko B., Lien E., Agostoni C., et al. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J. Perinat. Med. 36 (2008) 5-14
18. Atkinson S.A., and Koletzko B. Determining life-stage groups and extrapolating nutrient intake values (NIVs). Food Nutr. Bull. 28 (2007) S61-S76
19. Christ S.E. Asbjorn Folling and the discovery of phenylketonuria. J. Hist. Neurosci. 12 (2003) 44-54
20. Erlandsen H., and Stevens R.C. The structural basis of phenylketonuria. Mol. Genet. Metab. 68 (1999) 103-125
21. Eisensmith R.C., and Woo S.L. Molecular basis of phenylketonuria and related hyperphenylalaninemias: mutations and polymorphisms in the human phenylalanine hydroxylase gene. Hum. Mutat. 1 (1992) 13-23
22. Scriver C.R., Eisensmith R.C., and Woo S.L.C. The hyperphenylalaninemias. The Metabolic and Molecular Bases of Inherited Disease. 7th ed. (1995), McGraw-Hill, New York 1015-1075
23. Bickel H., Gerrard J., and Hickmans E.M. Influence of phenylalanine intake on phenylketonuria. Lancet 265 (1953) 812-813
24. MacDonald A. Diet and compliance in phenylketonuria. Eur. J. Pediatr. 159 (2000) S136-S141
25. Sanjurjo P., Perteagudo L., Rodriguez Soriano J., Vilaseca A., and Campistol J. Polyunsaturated fatty acid status in patients with phenylketonuria. J. Inherit. Metab. Dis. 17 (1994) 704-709
26. Galli C., Agostoni C., Mosconi C., Riva E., Salari P.C., and Giovannini M. Reduced plasma C-20 and C-22 polyunsaturated fatty acids in children with phenylketonuria during dietary intervention. J. Pediatr. 119 (1991) 562-567
27. Giovannini M., Biasucci G., Agostoni C., Luotti D., and Riva E. Lipid status and fatty acid metabolism in phenylketonuria. J. Inherit. Metab. Dis. 18 (1995) 265-272
28. Poge A.P., Baumann K., Muller E., Leichsenring M., Schmidt H., and Bremer H.J. Long-chain polyunsaturated fatty acids in plasma and erythrocyte membrane lipids of children with phenylketonuria after controlled linoleic acid intake. J. Inherit. Metab. Dis. 21 (1998) 373-381
29. van Gool C.J., van Houwelingen A.C., and Hornstra G. The essential fatty acid status in phenylketonuria patients under treatment. J. Nutr. Biochem. 11 (2000) 543-547
30. Burgard P., Schmidt E., Rupp A., Schneider W., and Bremer H.J. Intellectual development of the patients of the German Collaborative Study of children treated for phenylketonuria. Eur. J. Pediatr. 155 (1996) S33-S38
31. Stemerdink B.A., Kalverboer A.F., van der Meere J.J., et al. Behaviour and school achievement in patients with early and continuously treated phenylketonuria. J. Inherit. Metab. Dis. 23 (2000) 548-562
32. Koletzko B., Sauerwald T., Demmelmair H., et al. Dietary long-chain polyunsaturated fatty acid supplementation in infants with phenylketonuria: a randomized controlled trial. J. Inherit. Metab. Dis. 30 (2007) 326-332
33. Agostoni C., Harvie A., McCulloch D.L., et al. A randomized trial of long-chain polyunsaturated fatty acid supplementation in infants with phenylketonuria. Dev. Med. Child. Neurol. 48 (2006) 207-212
34. Agostoni C., Riva E., Biasucci G., et al. The effects of n-3 and n-6 polyunsaturated fatty acids on plasma lipids and fatty acids of treated phenylketonuric children. Prostaglandins Leukot Essent. Fatty Acids 53 (1995) 401-404
35. Innis S.M., Nelson C.M., Rioux M.F., and King D.J. Development of visual acuity in relation to plasma and erythrocyte omega-6 and omega-3 fatty acids in healthy term gestation infants. Am. J. Clin. Nutr. 60 (1994) 347-352
36. Luukkainen P., Salo M.K., Visakorpi J.K., Raiha N.C., and Nikkari T. Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. J. Pediatr. Gastroenterol. Nutr. 23 (1996) 229-234
37. Cleary M.A., Feillet F., White F.J., et al. Randomised controlled trial of essential fatty acid supplementation in phenylketonuria. Eur. J. Clin. Nutr. 60 (2006) 915-920
38. Agostoni C., Massetto N., Biasucci G., et al. Effects of long-chain polyunsaturated fatty acid supplementation on fatty acid status and visual function in treated children with hyperphenylalaninemia. J. Pediatr. 137 (2000) 504-509
39. Henderson R.M., McCulloch D.L., Herbert A.M., Robinson P.H., and Taylor M.J. Visual event-related potentials in children with phenylketonuria. Acta Paediatr. 89 (2000) 52-57
40. Leuzzi V., Rinalduzzi S., Chiarotti F., Garzia P., Trasimeni G., and Accornero N. Subclinical visual impairment in phenylketonuria. a neurophysiological study (VEP-P) with clinical, biochemical, and neuroradiological (MRI) correlations. J. Inherit. Metab. Dis. 21 (1998) 351-364
41. Beblo S., Reinhardt H., Muntau A.C., Mueller-Felber W., Roscher A.A., and Koletzko B. Fish oil supplementation improves visual evoked potentials in children with phenylketonuria. Neurology 57 (2001) 1488-1491
42. Beblo S., Reinhardt H., Demmelmair H., Muntau A.C., and Koletzko B. Effect of fish oil supplementation on fatty acid status, coordination, and fine motor skills in children with phenylketonuria. J. Pediatr. 150 (2007) 479-484
43. Decsi T., and Koletzko B. Fatty acid composition of plasma lipid classes in healthy subjects from birth to young adulthood. Eur. J. Pediatr. 153 (1994) 520-525
44. E. Kurth, Motometrische Rostock-Oseretzky-Skala, Psychodiagnostisches Zentrum, Berlin, Deutschland, Sektion Psychologie der Humbld-Universität, 1985.