Metabolism and functions of highly unsaturated fatty acids: An update

Lipids

Volumn 36, Issue 9, 2001, Pages 961-964

  Nakaruma, Manabu T ^a   Cho, Hyekyung P ^b   Xu, Jing ^b   Tang, Zhongren ^b   Clarke, Steven D ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BIOSYNTHESIS; BRAIN; CLONING; ENZYME INHIBITION; FETAL MONITORING; GENES; METABOLISM; NUTRITION; OXIDATION; RNA; TISSUE; UNSATURATED COMPOUNDS;

ION-CHANNEL MODULATION;

FATTY ACIDS;

LINOLEOYL COENZYME A DESATURASE; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNSATURATED FATTY ACID;

ALPHA TOCOPHEROL DEFICIENCY; BODY FAT; DEGRADATION; ENDOCYTOSIS; ENZYME INDUCTION; ENZYME INHIBITION; ESSENTIAL FATTY ACID DEFICIENCY; EXOCYTOSIS; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; MOLECULAR CLONING; PEROXISOME; REVIEW;

ANIMALS; DIET; FATTY ACID DESATURASES; FATTY ACIDS, UNSATURATED; HUMANS; LINOLEOYL-COA DESATURASE; OXIDATION-REDUCTION; PEROXISOME PROLIFERATORS;

MAMMALIA;

EID: 0035165337     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-001-0806-5     Document Type: Review

References (41)

1. α-Linolenic acid: Functions and effects on linoleic acid metabolism and eicosanoid-mediated reactions
2. Cloning, expression, and nutritional regulation of the mammalian Δ-6 desaturase
3. Purification and partial characterization of linoleoyl-CoA desaturase from rat liver microsomes
4. Cloning, expression, and fatty acid regulation of the human Δ-5 desaturase
5. The majority of dietary linoleate in growing rats is β-oxidized or stored in visceral fat
6. 13C]linolenate utilization in the developing rat brain
7. Biosynthesis of Prostaglandins
8. Peroxisomal β-oxidation and polyunsaturated fatty acids
9. Lipid metabolism in peroxisomes in relation to human disease
10. Coordinate induction of peroxisomal acyl-CoA oxidase and UCP-3 by dietary fish oil: A mechanism for decreased body fat deposition
11. Comparative effects of perilla and fish oils on the activity and gene expression of fatty acid oxidation enzymes in rat liver
12. Dietary γ-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid β-oxidation in rats
13. Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene
14. Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor
15. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
16. Fatty acids and eicosanoids regulate gene expression through direct interaction with peroxisome proliferator-activated receptors α and γ
17. Peroxisome proliferators enhance linoleic acid metabolism in rat liver: Increased biosynthesis of ω6 polyunsaturated fatty acids
18. Increased hepatic Δ6-desaturase activity with growth hormone expression in the MG101 transgenic mouse
19. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
20. Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: Possible mechanisms
21. From studies of biochemical mechanism to novel biological mediators: Prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel lecture, 8 December 1982
22. Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid
23. Prevention of cardiac sudden death by n-3 fatty acids: A review of the evidence
24. Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro
25. Dietary polyunsaturated fatty acid regulation of gene transcription
26. Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α
27. Sterol regulatory element binding protein-1 (SREBP-1) expression is suppressed by dietary polyunsaturated fatty acids: A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fats
28. Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decay
29. Essential fatty acid deficiency
30. The effect of vitamin E and synthetic antioxidants on the growth in vitro of explanted rat embryos
31. Time-dependent effects of progressive γ-linolenate feeding on hyperphagia, weight gain, and erythrocyte fatty acid composition during growth of zucker obese rats
32. Lipid accumulation and body fat distribution is influenced by type of dietary fat fed to rats
33. Dietary fatty acid composition influences energy accretion in rats
34. Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults
35. Reduced adipose 18:3 ω3 with weight loss by very low calorie dieting
36. The body composition and lipid metabolic effects of long-term ethanol feeding during a high ω6 polyunsaturated fatty acid diet in micropigs
37. Abnormal polyunsaturated lipid metabolism in the obese zucker rat, with partial metabolic correction by γ-linolenic acid administration
38. Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter
39. Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
40. Regulation of hepatic Δ-6-desaturase expression and its role in the polyunsaturated fatty acid inhibition of fatty acid synthase gene expression in mice