Evaluation of vitreous levels of gatifloxacin after systemic administration in inflamed and non-inflamed eyes

Acta Ophthalmologica

Volumn 87, Issue 6, 2009, Pages 648-652

  Rajpal, T ^a   Srinivas, Ambatipudi ^a   Azad, Raj Vardhan ^a   Sharma, Yog Raj ^a   Kumar, Atul ^a   Satpathy, Gita ^a   Velpandian, Thirumurthy ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Endophthalmitis; Gatifloxacin; Intravitreal penetration

Indexed keywords

ANTIBIOTIC AGENT; GATIFLOXACIN;

ADULT; ARTICLE; CILIARY DISK; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG PENETRATION; ENDOPHTHALMITIS; EYE INFLAMMATION; FEMALE; HUMAN; MALE; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; SINGLE DRUG DOSE; VITRECTOMY; VITREOUS BODY;

ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPHTHALMITIS; FEMALE; FLUOROQUINOLONES; HUMANS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; TIME FACTORS; VITREOUS BODY;

EID: 69449098609     PISSN: 1755375X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2008.01323.x     Document Type: Article

References (33)

1. Affeldt JC, Flynn HW Jr., Forster RK, Mandelbaum S, Clarkson JG Jarus GD (1987 Microbial endophthalmitis resulting from ocular trauma. Ophthalmology 94 : 407 413.
2. Aguilar HE, Meredith TA, el-Massry A et al. (1995a Vancomycin levels after intravitreal injection. Effects of inflammation and surgery. Retina 15 : 428 432.
3. Aguilar HE, Meredith TA, Shaarawy A, Kincaid M Dick J (1995b Vitreous cavity penetration of ceftazidime after intravenous administration. Retina 15 : 154 159.
4. Anuradha S Feyi-Waboso A (2006 The use of control charts in monitoring endophthalmitis. Acta Ophthalmol Scand 84 : 440 441.
5. Barza M, Lynch E Baum JL (1993 Pharmacokinetics of newer cephalosporins after subconjunctival and intravitreal injection in rabbits. Arch Ophthalmol 111 : 121 125.
6. Bauernfeind A (1997 Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin. J Antimicrob Chemother 40 : 639 651.
7. Bearden DT Danziger LH (2001 Mechanism of action of and resistance to quinolones. Pharmacotherapy 21 (Suppl.) : 224 232.
8. Brown GC, Eagle RC, Shakin EP, Gruber M Arbizio VV (1990 Retinal toxicity of intravitreal gentamicin. Arch Ophthalmol 108 : 1740 1744.
9. Cekic O, Batman C, Yasar U, Basci NE, Bozkurt A Kayaalp SO (1999 Human aqueous and vitreous humour levels of ciprofloxacin following oral and topical administration. Eye 13 : 555 558.
10. Clark WL, Kaiser PK, Flynn HW Jr., Belford A, Miller D Meisler DM (1999 Treatment strategies and visual acuity outcomes in chronic postoperative Propionibacterium acnes endophthalmitis. Ophthalmology 106 : 1665 1670.
11. Cobo LM Forster RK (1981 The clearance of intravitreal gentamicin. Am J Ophthalmol 92 : 59 62.
12. D'Amico DJ Nourily SW (1994 Postoperative endophthalmitis. In : Albert DA Jacobiec FA (eds). Principles and Practice of Ophthalmology. Retina and Vitreous. Philadelphia : WB Saunders 1159 1169.
13. Donnenfeld ED, Perry HD, Snyder RW, Moadel R, Elsky M Jones H (1997 Intracorneal, aqueous humour, and vitreous humour penetration of topical and oral Ofloxacin. Arch Ophthalmol 115 : 173 176.
14. Ednie LM, Jacobs MR Appelbaum PC (1998 Activities of gatifloxacin compared to those of seven other agents against anaerobic organisms. Antimicrob Agents Chemother 42 : 2459 2462.
15. Endophthalmitis Vitrectomy Study Group (1995 Results of the Endophthalmitis Vitrectomy Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis: Endophthalmitis Vitrectomy Study Group. Arch Ophthalmol 113 : 1479 1496.
16. Fiscella RG, Nguyen TK, Cwik MJ et al. (1999 Aqueous and vitreous penetration of levofloxacin after oral administration. Ophthalmology 106 : 2286 2290.
17. Garcia-Saenz MC, Arias-Puente A, Fresnadillo-Martinez MJ Carrasco-Font C (2001 Human aqueous humour levels of oral ciprofloxacin, levofloxacin, and moxifloxacin. J Cataract Refract Surg 27 : 1969 1974.
18. Grasela DM (2000 Clinical pharmacology of gatifloxacin, a new fluoroquinolone. Clin Infect Dis 31 (Suppl.) : 51 58.
19. Han DP, Wisniewski SR, Wilson LA, Barza M, Vine AK, Doft BH Kelsey SF (1996 Spectrum and susceptibilities of microbiologic isolates in the Endophthalmitis Vitrectomy Study. Am J Ophthalmol 122 : 1 17. (Pubitemid 26230889)
20. Hariprasad SM, Mieler WF Holz ER (2002 Vitreous penetration of orally administered gatifloxacin in humans. Trans Am Ophthalmol Soc 100 : 153 159.
21. Hariprasad SM, Mieler WF Holz ER (2003 Vitreous and aqueous penetration of orally administered gatifloxacin in humans. Arch Ophthalmol 121 : 345 350.
22. Kresloff MS Castellarin AA (1998 Endophthalmitis - major review. Surv Ophthalmol 43 : 193 224.
23. Lesk MR, Ammann H, Marcil G, Vinet B, Lamer L Sebag M (1993 The penetration of oral ciprofloxacin into the aqueous humour, vitreous, and subretinal fluid of humans. Am J Ophthalmol 115 : 623 628.
24. Levine C, Hiasa H Marians KJ (1998 DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities. Biochem Biophys Acta 1400 : 29 43.
25. Lindland A Slagsvold JE (2007 Binocular endogenous Clostridium septicum endophthalmitis. Acta Ophthalmol Scand 85 : 232 234.
26. el-Massry A, Meredith TA, Aguilar HE, Shaarawy A, Kincaid M, Dick J Mahmoud MI (1996 Aminoglycoside levels in the rabbit vitreous cavity after intravenous administration. Am J Ophthalmol 122 : 684 689.
27. Ness T, Pelz K Hansen LL (2007 Endogenous endophthalmitis: micro-organisms, disposition and prognosis. Acta Ophthalmol Scand 85 : 852 856.
28. Oshika T, Hatano H, Kuwayama Y et al. (2007 Incidence of endophthalmitis after cataract surgery in Japan. Acta Ophthalmol Scand 85 : 848 851.
29. Oum BS, D'Amico DJ, Kwak HW Wong KW (1992 Intravitreal antibiotic therapy with vancomycin and aminoglycoside: examination of the retinal toxicity of repetitive injections after vitreous and lens surgery. Graefes Arch Clin Exp Ophthalmol 230 : 56 61.
30. Seawright AA, Bourke RD Cooling RJ (1996 Macula toxicity after intravitreal amikacin. Aust N Z J Ophthalmol 24 : 143 146.
31. Shaarawy A, Meredith TA, Kincaid M, Dick J, Aguilar E, Ritchie DJ Reichley RM (1995 Intraocular injection of ceftazidime. Effects of inflammation and surgery. Retina 15 : 433 438.
32. Yalvac IS, Basci NE, Bozkurt A Duman S (2003 Penetration of topically applied ciprofloxacin and ofloxacin into the aqueous humour and vitreous. J Cataract Refract Surg 29 : 487 491.
33. Zhao X, Xu C, Domagala J Drlica K (1997 DNA topoisomerase targets of the fluoroquinolones: a strategy for avoiding bacterial resistance. Proc Natl Acad Sci U S A 94 : 13991 13996.