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Volumn 60, Issue 9, 2009, Pages 2644-2654

Tumor necrosis factor α and RANKL blockade cannot halt bony spur formation in experimental inflammatory arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; COLLAGEN; IMMUNOGLOBULIN FC FRAGMENT; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PEGSUNERCEPT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 69449086400     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24767     Document Type: Article
Times cited : (64)

References (49)
  • 1
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003;423:356-361
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 2
    • 34249720998 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of rheumatoid arthritis
    • McInnes I, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Immunol 2007;7:429-442
    • (2007) Nat Immunol , vol.7 , pp. 429-442
    • McInnes, I.1    Schett, G.2
  • 3
    • 33846972636 scopus 로고    scopus 로고
    • Eating bone or adding it: The Wnt pathway decides
    • DOI 10.1038/nm0207-133, PII NM0207133
    • Goldring SR, Goldring MB. Eating bone or adding it: the Wnt pathway decides. Nat Med 2007;13:133-134 (Pubitemid 46245758)
    • (2007) Nature Medicine , vol.13 , Issue.2 , pp. 133-134
    • Goldring, S.R.1    Goldring, M.B.2
  • 4
    • 34249800645 scopus 로고    scopus 로고
    • TNF blockers and structural remodeling in ankylosing spondylitis - What is reality and what is fiction?
    • Schett G, Landewe R, van der Heijde D. TNF blockers and structural remodeling in ankylosing spondylitis - what is reality and what is fiction? Ann Rheum Dis 2007;66:709-711
    • (2007) Ann Rheum Dis , vol.66 , pp. 709-711
    • Schett, G.1    Landewe, R.2    Van Der Heijde, D.3
  • 5
    • 0034523328 scopus 로고    scopus 로고
    • TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
    • Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL. TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 2000;106:1481-1488 (Pubitemid 32038586)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.12 , pp. 1481-1488
    • Lam, J.1    Takeshita, S.2    Barker, J.E.3    Kanagawa, O.4    Ross, F.P.5    Teitelbaum, S.L.6
  • 8
    • 52449116752 scopus 로고    scopus 로고
    • Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors
    • Tat SK, Pelletier JP, Lajeunesse D, Fahmi H, Duval N, Martel-Pelletier J. Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors. Bone 2008;43:284-291
    • (2008) Bone , vol.43 , pp. 284-291
    • Tat, S.K.1    Pelletier, J.P.2    Lajeunesse, D.3    Fahmi, H.4    Duval, N.5    Martel-Pelletier, J.6
  • 9
    • 0036892685 scopus 로고    scopus 로고
    • Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: Semiquantitative and quantitative analysis
    • DOI 10.1136/ard.61.12.1047
    • Crotti T, Smith MD, Weedon H, Ahern MJ, Findlay DM, Kraan M, et al. Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semiquantitative and quantitative analysis. Ann Rheum Dis 2002;61:1047-1054 (Pubitemid 35397349)
    • (2002) Annals of the Rheumatic Diseases , vol.61 , Issue.12 , pp. 1047-1054
    • Crotti, T.N.1    Smith, M.D.2    Weedon, H.3    Ahern, M.J.4    Findlay, D.M.5    Kraan, M.6    Tak, P.P.7    Haynes, D.R.8
  • 10
    • 42049110350 scopus 로고    scopus 로고
    • OPG and RANKL regulation of bone remodeling in health and disease
    • Kearns AE, Khosla S, Kostenuik PJ. OPG and RANKL regulation of bone remodeling in health and disease. Endocr Rev 2008;29:155-192
    • (2008) Endocr Rev , vol.29 , pp. 155-192
    • Kearns, A.E.1    Khosla, S.2    Kostenuik, P.J.3
  • 14
    • 0034972517 scopus 로고    scopus 로고
    • Tumor necrosis factor α induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-κB: Abrogation of the tumor necrosis factor α effect by proteasome inhibitors
    • Sakai T, Kambe F, Mitsuyama H, Ishiguro N, Kurokouchi K, Takigawa M, et al. Tumor necrosis factor α induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-κB: abrogation of the tumor necrosis factor α effect by proteosome inhibitors. J Bone Miner Res 2001;16:1272-1280 (Pubitemid 32574656)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.7 , pp. 1272-1280
    • Sakai, T.1    Kambe, F.2    Mitsuyama, H.3    Ishiguro, N.4    Kurokouchi, K.5    Takigawa, M.6    Iwata, H.7    Seo, H.8
  • 16
    • 0026806992 scopus 로고
    • Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases
    • Cope AP, Aderka D, DohertyM, Engelmann H, Gibbons D, Jones AC, et al. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis Rheum 1992;35:1160-1169
    • (1992) Arthritis Rheum , vol.35 , pp. 1160-1169
    • Cope, A.P.1    Aderka, D.2    Doherty, M.3    Engelmann, H.4    Gibbons, D.5    Jones, A.C.6
  • 17
    • 0038131975 scopus 로고    scopus 로고
    • Therapeutic strategies for rheumatoid arthritis
    • Smolen JS, Steiner G. Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2003;2:473-488
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 473-488
    • Smolen, J.S.1    Steiner, G.2
  • 18
    • 0021021940 scopus 로고
    • The enthesopathy of ankylosing spondylitis
    • Ball J. The enthesopathy of ankylosing spondylitis. Br J Rheumatol 1983;22(4 Suppl 2):25-28
    • (1983) Br J Rheumatol , vol.22 , Issue.4 SUPPL. 2 , pp. 25-28
    • Ball, J.1
  • 19
    • 40549109246 scopus 로고    scopus 로고
    • Critical appraisal of assessment of structural damage in ankylosing spondylitis: Implications for treatment outcomes
    • [review]
    • Sieper J, Appel H, Braun J, Rudwaleit M. Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes [review]. Arthritis Rheum 2008;58:649-656
    • (2008) Arthritis Rheum , vol.58 , pp. 649-656
    • Sieper, J.1    Appel, H.2    Braun, J.3    Rudwaleit, M.4
  • 20
    • 20444478272 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis
    • DOI 10.1172/JCI23738
    • Lories RJ, Derese I, Luyten FP. Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 2005;115:1571-1579 (Pubitemid 40814665)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.6 , pp. 1571-1579
    • Lories, R.J.U.1    Derese, I.2    Luyten, F.P.3
  • 21
    • 0346220031 scopus 로고    scopus 로고
    • Reduction of Osteophyte Formation and Synovial Thickening by Adenoviral Overexpression of Transforming Growth Factor β/Bone Morphogenetic Protein Inhibitors during Experimental Osteoarthritis
    • DOI 10.1002/art.11328
    • Scharstuhl A, Vitters EL, van der Kraan PM, van den Berg WB. Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor β/bone morphogenetic protein inhibitors during experimental osteoarthritis. Arthritis Rheum 2003;48:3442-3451 (Pubitemid 37531910)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.12 , pp. 3442-3451
    • Scharstuhl, A.1    Vitters, E.L.2    Van Der Kraan, P.M.3    Van Den Berg, W.B.4
  • 26
    • 33847077596 scopus 로고    scopus 로고
    • Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis
    • DOI 10.1002/art.22372
    • Lories RJ, Derese I, De Bari C, Luyten FP. Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum 2007;56:489-497 (Pubitemid 46271975)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.2 , pp. 489-497
    • Lories, R.J.U.1    Derese, I.2    De Bari, C.3    Luyten, F.P.4
  • 28
    • 0742304737 scopus 로고    scopus 로고
    • Osteoclast Numbers in Lewis Rats with Adjuvant-induced Arthritis: Identification of Preferred Sites and Parameters for Rapid Quantitative Analysis
    • DOI 10.1354/vp.41-1-30
    • Bolon B, Morony S, Cheng Y, Hu YL, Feige U. Osteoclast numbers in Lewis rats with adjuvant-induced arthritis: identification of preferred sites and parameters for rapid quantitative analysis. Vet Pathol 2004;41:30-36 (Pubitemid 38146844)
    • (2004) Veterinary Pathology , vol.41 , Issue.1 , pp. 30-36
    • Bolon, B.1    Morony, S.2    Cheng, Y.3    Hu, Y.-L.4    Feige, U.5
  • 30
    • 0036068297 scopus 로고    scopus 로고
    • Kinetics of bone protection by recombinant osteoprotegerin therapy in Lewis rats with adjuvant arthritis
    • DOI 10.1002/art.10369
    • Campagnuolo G, Bolon B, Feige U. Kinetics of bone protection by recombinant osteoprotegerin therapy in Lewis rats with adjuvant arthritis. Arthritis Rheum 2002;46:1926-1936 (Pubitemid 34774526)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.7 , pp. 1926-1936
    • Campagnuolo, G.1    Bolon, B.2    Feige, U.3
  • 32
    • 20844434038 scopus 로고    scopus 로고
    • Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models
    • DOI 10.1002/art.21021
    • Schett G, Middleton S, Bolon B, Stolina M, Brown H, Zhu L, et al. Additive bone-protective effects of anabolic treatment when used in conjuction with RANKL and tumor necrosis factor inhibition in two rat arthritis models. Arthritis Rheum 2005;52:1604-1611 (Pubitemid 40663953)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.5 , pp. 1604-1611
    • Schett, G.1    Middleton, S.2    Bolon, B.3    Stolina, M.4    Brown, H.5    Zhu, L.6    Pretorius, J.7    Zack, D.J.8    Kostenuik, P.9    Feige, U.10
  • 33
    • 0035188095 scopus 로고    scopus 로고
    • The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites
    • Benjamin M, McGonagle D. The anatomical basis for disease localization in seronegative spondylarthropathy at entheses and related sites. J Anat 2001;199:503-526 (Pubitemid 33094612)
    • (2001) Journal of Anatomy , vol.199 , Issue.5 , pp. 503-526
    • Benjamin, M.1    McGonagle, D.2
  • 34
    • 33749518855 scopus 로고    scopus 로고
    • Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
    • DOI 10.1016/j.bone.2006.05.006, PII S8756328206004856
    • Iwata K, Li J, Follet H, Phipps RJ, Burr DB. Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia. Bone 2006;39:1053-1058 (Pubitemid 44528380)
    • (2006) Bone , vol.39 , Issue.5 , pp. 1053-1058
    • Iwata, K.1    Li, J.2    Follet, H.3    Phipps, R.J.4    Burr, D.B.5
  • 36
    • 61649090805 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model
    • Kitaori T, Ito H, Schwarz EM, Tsutsumi R, Yoshitomi H, Oishi S, et al. Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. Arthritis Rheum 2009;60:813-823
    • (2009) Arthritis Rheum , vol.60 , pp. 813-823
    • Kitaori, T.1    Ito, H.2    Schwarz, E.M.3    Tsutsumi, R.4    Yoshitomi, H.5    Oishi, S.6
  • 37
    • 41949084084 scopus 로고    scopus 로고
    • Effects of long-term estrogen replacement therapy on bone turnover in periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys
    • Olson EJ, Lindgren BR, Carlson CS. Effects of long-term estrogen replacement therapy on bone turnover in periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys. Bone 2008;42:907-913
    • (2008) Bone , vol.42 , pp. 907-913
    • Olson, E.J.1    Lindgren, B.R.2    Carlson, C.S.3
  • 39
    • 34548235937 scopus 로고    scopus 로고
    • Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair
    • DOI 10.1359/jbmr.070318
    • Amanat N, McDonald M, Godfrey C, Bilston L, Little D. Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair. J Bone Miner Res 2007;22:867-876 (Pubitemid 351339747)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.6 , pp. 867-876
    • Amanat, N.1    McDonald, M.2    Godfrey, C.3    Bilston, L.4    Little, D.5
  • 40
    • 22244454036 scopus 로고    scopus 로고
    • Osteoprotegerin treatment impairs remodeling and apparent material properties of callus tissue without influencing structural fracture strength
    • DOI 10.1007/s00223-004-0126-9
    • Ulrich-Vinther M, Andreassen TT. Osteoprotegerin treatment impairs remodeling and apparent material properties of callus tissue without influencing structural fracture strength. Calcif Tissue Int 2005;76:280-286 (Pubitemid 40991399)
    • (2005) Calcified Tissue International , vol.76 , Issue.4 , pp. 280-286
    • Ulrich-Vinther, M.1    Andreassen, T.T.2
  • 41
  • 42
    • 1942532044 scopus 로고    scopus 로고
    • Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: A model of psoriatic arthritis
    • DOI 10.1136/ard.2003.013599
    • Lories RJ, Matthys P, de Vlam K, Derese I, Luyten FP. Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann Rheum Dis 2004;63:595-598 (Pubitemid 38530208)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.5 , pp. 595-598
    • Lories, R.J.U.1    Matthys, P.2    De Vlam, K.3    Derese, I.4    Luyten, F.P.5
  • 43
    • 0025238946 scopus 로고
    • Impact of NSAIDS on murine antigen induced arthritis. II. A light microscopic investigation of antiinflammatory and bone protective effects
    • De Vries BJ, van den Berg WB. Impact of NSAIDS on murine antigen induced arthritis. II. A light microscopic investigation of antiinflammatory and bone protective effects. J Rheumatol 1990;17:295-303.
    • (1990) J Rheumatol , vol.17 , pp. 295-303
    • De Vries, B.J.1    Van Den Berg, W.B.2
  • 44
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
    • DOI 10.1038/319516a0
    • Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factor. Nature 1986;319:516-518 (Pubitemid 16212936)
    • (1986) Nature , vol.319 , Issue.6053 , pp. 516-518
    • Bertoli, D.R.1    Nedwin, G.E.2    Bringman, T.S.3
  • 45
    • 0023542724 scopus 로고
    • Effects of tumor necrosis factor on bone formation in vitro
    • Canalis E. Effects of tumor necrosis factor on bone formation in vitro. Endocrinology 1987;121:1596-1604 (Pubitemid 18012760)
    • (1987) Endocrinology , vol.121 , Issue.5 , pp. 1596-1604
    • Canalis, E.1
  • 46
    • 42949084641 scopus 로고    scopus 로고
    • Inhibition of osteoclasts does not prevent joint ankylosis in a mouse model of spondyloarthritis
    • DOI 10.1093/rheumatology/ken082
    • Lories RJ, Derese I, Luyten FP. Inhibition of osteoclasts does not prevent joint ankylosis in a mouse model of spondyloarthritis. Rheumatology (Oxford) 2008;47:605-608 (Pubitemid 351619197)
    • (2008) Rheumatology , vol.47 , Issue.5 , pp. 605-608
    • Lories, R.J.U.1    Derese, I.2    Luyten, F.P.3
  • 47
    • 8444242547 scopus 로고    scopus 로고
    • The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis
    • for the Health, Aging and Body Composition Study
    • Carbone LD, Nevitt MC, Wildy K, Barrow KD, Harris F, Felson D, et al, for the Health, Aging and Body Composition Study. The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum 2004;50:3516-3525
    • (2004) Arthritis Rheum , vol.50 , pp. 3516-3525
    • Carbone, L.D.1    Nevitt, M.C.2    Wildy, K.3    Barrow, K.D.4    Harris, F.5    Felson, D.6
  • 48
    • 33344469853 scopus 로고    scopus 로고
    • Denosumab in postmenopausal women with low bone mineral density
    • for the AMG 162 Bone Loss Study Group
    • McClung MR, Lewiecki EM, Cohen SB, Bolognese MA, Woodson GC, Moffett AH, et al, for the AMG 162 Bone Loss Study Group. Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 2006;354:821-831
    • (2006) N Engl J Med , vol.354 , pp. 821-831
    • McClung, M.R.1    Lewiecki, E.M.2    Cohen, S.B.3    Bolognese, M.A.4    Woodson, G.C.5    Moffett, A.H.6
  • 49
    • 4544255312 scopus 로고    scopus 로고
    • Impact of degenerative spinal diseases on bone mineral density of the lumbar spine in elderly women
    • DOI 10.1007/s00198-004-1600-y
    • Muraki S, Yamamoto S, Ishibashi H, Horiuchi T, Hosoi T, Orimo H, et al. Impact of degenerative spinal diseases on bone mineral density of the lumbar spine in elderly women. Osteoporos Int 2004;15:724-728 (Pubitemid 39222655)
    • (2004) Osteoporosis International , vol.15 , Issue.9 , pp. 724-728
    • Muraki, S.1    Yamamoto, S.2    Ishibashi, H.3    Horiuchi, T.4    Hosoi, T.5    Orimo, H.6    Nakamura, K.7


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